Epigenetic Signatures in Ovarian Cancer to Determine Potential Diagnostic/Prognostic Biomarkers by Tuba Gunel, Maurice Jansen, Samet Topuz, Jean Helmijr, Servet Tunoğlu, Tugce Senturk Kirmizitas

“…Integration with The Cancer Genome Atlas (TCGA) data identified differentially expressed genes (DEGs) for functional analysis.Results: The analysis revealed significant alterations in DNA methylation patterns, with 62 hypermethylated and 2 hypomethylated DMRs in OC compared with HBDs. …”
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Simultaneous dual-target magnetic resonance-guided focused ultrasound treatment for patients with tremor-dominant Parkinson’s disease by Rezida M. Galimova, Sergey N. Illarioshkin, Gulnara N. Akhmadeeva, Dinara I. Nabiullina, Felix F. Kashapov, Shamil M. Safin, Igor V. Buzaev, Dinara R. Teregulova, Yulia A. Sidorova, Olga V. Kachemaeva

“…Outcomes of ablation with dual targeting of two subcortical nuclei to improve functional treatment results are yet to be explored. …”
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Comparison of primary and secondary stability of a one-piece compressive conometric implant system in the posterior upper and lower jaws by Thabat R. Al-Hity, Thabat R. Al-Hity, Thabat R. Al-Hity, Bilal El-Dhuwaib, Abdulsalam R. Al-Zahawi, Sarhang Sarwat Gul, Sarhang Sarwat Gul

“…BackgroundImplant stability plays a key role in establishing implant osseointegration and is a crucial factor in determining the appropriate timing for functional loading with a fixed prosthesis. This study aims to investigate the primary and secondary stability of a one-piece compressive conometric implant system in the posterior upper and lower jaws.Materials and methodsA total of 46 compressive one-piece dental implants (DIs) from ROOTT Trade Company were placed in the upper and lower jaws. …”
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Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions by Magdalena Rosa-Bończak Rosa, Patrycja Marta, Filip Maciej Huzarski, Klaudia Anna Pawełek, Gabriela Monika Ferfecka, Agata Ossolińska, Natalia Morawiecka, Lucyna Stolarska, Oliver Carlton, Weronika Kłosowicz

“…Chronic stress, obesity, and other factors accompanying sleep disturbances can impair the functioning of hormonal axes, ultimately leading to oxidative stress—a metabolic basis for fertility issues. …”
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Automated protocol templates with efficient schedule of activities table generation for healthy volunteer trials by Kyongeun Shin, Sungpil Han, Hyerim Choe, Suein Choi, Seunghoon Han

“…Additionally, a web-based SoA generator (developed with React.js) was created, featuring user-friendly functions for flexible start day adjustments, trial parameter settings, and automatic annotations. …”
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Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microbiota by Yunjiao Shen, Yunjiao Shen, Yansong Gao, Ge Yang, Zijian Zhao, Yujuan Zhao, Lei Gao, Shengyu Li

“…Total minor ginsenosides (TMG) were obtained through the fermentation of major ginsenosides with Lactiplantibacillus plantarum, and potential anticancer effects of TMGs on the mouse colon cancer cell line CT26.WT, in vitro and in vivo, were investigated.Materials and MethodsWe employed the Cell Counting Kit-8 (CCK-8), TdT-mediated dUTP nick end labeling (TUNEL), and Western blot analysis in vitro to explore the anti-proliferative and pro-apoptotic functions of TMG in CT26.WT cells. …”
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Antimicrobial and prebiotic properties of Weissella confuse B4-2 exopolysaccharide and its effects on matrix metalloproteinase genes expression by Maryam Firoozi, Mahdieh Shirzad, Elahe Motevaseli, Razieh Dalirfardouei, Mohammad Hossein Modarresi, Rezvan Najafi

“…FT-IR, SEM, and HPTLC analyzed functional groups, spatial structure, and EPS units. …”
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Optimized non-toxic double absorber perovskite solar cell with efficiency beyond 33% by Sheikh Hasib Cheragee, Jannatul Afroj Akhi, Mishion Dev, Md. Mahfuzul Haque, Md. Alomgir Kabir, Tamim Hossain, Mohammad Tahsin Alam, Mohammad Jahangir Alam

“…To address these issues, this study explores a double absorber solar cell (DASC) composed of Cs2TiBr6 and La2NiMnO6 as an alternative to lead-based perovskite absorbers. These materials offer both safety and stability advantages. …”
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DETERMINATION OF THE STABILITY OF A LOCAL ANESTHETIC BROMOKAIN TRANSDERMAL THERAPEUTIC SYSTEM by V. A. Ryzhikova, E. G. Kuznetsova, V. Yu. Belov, L. A. Salomatina, V. I. Sevastianov

“…Unlike the samples containing 50 mg of bromokain, TTS with 100 mg of the anesthetic demonstrated changes in the physical confi guration and deterioration of the functional properties after the 6th month of storage. …”
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Ocular Toxicity Associated with Tamoxifen Administration in Patients with Breast Cancer: A Systematic Review by Tejaswi Vadde, Neha Narayan, Amulya Varshini Banka, Shravani Divity, Yethindra Vityala

“…The analysis revealed that TAM-induced ocular toxicity results in diverse structural and functional changes within eye tissues, including retinal degeneration, macular thinning, alterations in choroidal thickness, and vascular modifications. …”
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Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles by O. A. Puchenkova, O. V. Shheblykina, D. A. Kostina, A. A. Bolgov, P. R. Lebedev, V. V. Molchanov, T. G. Pokrovskaya, M. V. Korokin, E. A. Nikiforov, N. F. Vaskina, T. A. Idrisov, T. D. Moseev, V. V. Melekhin, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin

“…To study the acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles.Materials and methods. The study was performed on white laboratory female BALB/c mice (n=57) and male C57Bl/6 mice (n=66). …”
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Effects of fish meal replacement with composite proteins source on growth performance, antioxidant capacity and swim bladder quality of chu’s croaker (Nibea coibor) by Chunsheng Liu, Xin Liu, Jiarong Cai, Yuping Wang, Shuqi Wang, Xiaobo Wen, Hua Rong, Lanfei Xiao, Fan Lin

“…Collagen, as a commercial functional protein, is widely applied in food, cosmetics, biomedicine and other industries, and swim bladder is regarded as an ideal source of raw materials due to its rich collagen content. …”
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Research of tomatoes Solanum lycopersicum L. originating from different climatic-geographical regions and identification of metabolites by tandem mass spectrometry by O. A. Chunikhina, M. P. Razgonova, A. M. Zakharenko, K. S. Golokhvast

“…The findings will help to intensify future research into the development and production of various functional food products containing targeted extracts of Solanum lycopersicum L.…”
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The impact of mobilization protocols on the length of postoperative hospitalization among cardiac surgery patients by V. V. Vitomskyi, O. B. Lazarieva, E. Yu. Doroshenko, M. V. Vitomskа, T. М. Kovalenko, A. М. Hertsyk, S. V. Gavreliuk

“…To determine the impact of implementing the extra early mobilization protocol (EEM) on the length of intensive care unit (LICU) stay and postoperative unit (LPOU) stay and to assess the role of age, heart contractility, functional class and surgical outcomes. Materials and methods. …”
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Surgical Treatment of Distal Radius Fractures Using Minimally Invasive Plate Osteosynthesis or Open Reduction and Internal Fixation: A Five-Year Comparative Follow-Up Study by Giuseppe Rovere, Pierfrancesco Pirri, Gianmarco Murgante, Vincenzo De Luna, Aurelio Testa, Giovanna Fidone, Francesco Liuzza, Pasquale Farsetti, Fernando De Maio

“…VLP fixation allowed better short-term recovery and anatomical restoration, but long-term functional outcomes were comparable.…”
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Smart Drug Delivery Systems Based on Cyclodextrins and Chitosan for Cancer Therapy by Larisa Păduraru, Alina-Diana Panainte, Cătălina-Anișoara Peptu, Mihai Apostu, Mădălina Vieriu, Tudor Bibire, Alexandru Sava, Nela Bibire

“…The majority of the cited references focus on the most notable research, studies of novel applications, and scientific advancements in the field of nanostructures and functional materials employed in oncological therapies over the last six years. …”
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Advancements in chondrocyte 3-dimensional embedded culture: Implications for tissue engineering and regenerative medicine by Yu-Ying Chu, Atsuhiko Hikita, Yukiyo Asawa, Kazuto Hoshi

“…However, in 2D culture, chondrocytes tend to lose their distinctive phenotypes and functionalities after serial passage, thereby limiting their efficacy for tissue engineering purposes.The mechanism of dedifferentiation in 2D culture can be attributed to various factors, including abnormal nuclear strength, stress-induced mitochondrial impairment, chromatin remodeling, ERK-1/2 and the p38/mitogen-activated protein kinase (MAPK) signaling pathway. …”
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COMPARATIVE ASSESSMENT OF PAIN AND LIFE QUALITY IN THE PATIENTS AFTER OPEN AND VIDEO-ASSISTED LOBECTOMY FOR LUNG CANCER by R. I. Yurin, E. V. Levchenko, V. A. Gluscheko, A. E. Mikhnin, S. M. Ergnyan, L. V. Gorokhov, N. E. Levchenko, N. V. Khandogin

“…When using the questionnaires of SF-36 (U = 8,742.50; p < 0.05) and EORTC QLQ-C30 (U = 3,759.00; p < 0.05) and the special module of QLQ-LC13 for lung cancer (U = 4,243.00; p < 0.05), the obtained data also indicated the better life quality and functions, reduction of pathologic manifestations versus open surgical access. …”
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Research Progress on Extraction, Isolation, Purification, Structure Characterization, and Bioactivities of Polysaccharides from Sugarcane Leaves and Bagasse by Jinhua LU, Qingxia YUAN, Zhenzhen YANG, Chunxiu HUANG, Ling Tang Pei, Zheng LI, Yaowen LIAO, Jian ZHANG, Longyan ZHAO, Xiaotao HOU, Jiagang DENG

“…The leaves and bagasse of sugarcane, an important food and economically significant crop, are recognized as two major residues. These materials are abundant in resources and rich in bioactive compounds, and their significant potential for the development of functional foods and health products is acknowledged. …”
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Utilization of Ultrasonic-Assisted Extraction for Bioactive Compounds from Floral Sources by Sepidar Seyyedi-Mansour, Pauline Donn, Maria Carpena, Franklin Chamorro, Paula Barciela, Ana Perez-Vazquez, Ana Olivia S. Jorge, Miguel A. Prieto

“…The increasing use of floral sources in manufacturing dietary supplements and functional foods, coupled with rapid advancements in these sectors, indicates significant potential for the application of UAE. …”
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