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GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR IN ADULTS WITH ARTERIAL HYPERTENSION
Published 2015-04-01“…The level of growth factor and its effector — insulin-like growth factor was lower (p<0,05) and body mass index was higher (p<0,001) in patients with increased blood pressure than in controls. …”
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Response of the tegument of Fasciola hepatica to infection and immunization sera in vitro
“…Concurrent release of microvesicles may also serve to both divert the immune response away from the fluke itself and permit delivery of immunomodulatory cargo to immune effector cells. …”
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Research on Automated On-Site Construction of Timber Structures: Mobile Construction Platform Guided by Real-Time Visual Positioning System
Published 2025-05-01“…In recent years, the AEC industry has increasingly sought sustainable solutions to enhance productivity and reduce environmental pollution, with wood emerging as a key renewable material due to its excellent carbon sequestration capability and low ecological footprint. …”
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Ability of protein epitope-containing constructs associated with melanoma to stimulate the cytotoxic activity of peripheral blood mononuclear cells against melanoma cells
Published 2019-02-01“…The aim of the study was to evaluate the ability of pMEL-TCI and pMEL-A0201 DNA-constructs encoding artificial polyepitope melanoma antigens to induce antitumor T cell immune response ex vivo. material and methods. Dendritic cells were obtained from peripheral blood mononuclear cells of HLA-A02:01-positive donors; DCs transfected with target DNA vaccine constructions were co-cultured with autologous T lymphocytes to stimulate anti-tumor effector T cells. …”
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The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer
Published 2020-10-01“…The study material included whole peripheral blood, blood plasma, and supernatants of suspension cultures of mononuclear leukocytes. …”
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Characterization of Shifts of the Cellular Component the Immune Status of Patients with Long-Term Course of Chronic Post-Traumatic Uveitis
Published 2021-04-01“…The most interesting, in our opinion, results were obtained by analyzing the relative number of effector cytotoxic cells of adaptive and nonspecific immunity. …”
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Navigating contradictions in enteric chemotactic stimuli
Published 2025-08-01“…The principal reservoir of intestinal indole is fecal matter, a complex biological material that contains both attractant and repellent stimuli. …”
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The Effect Components and Mechanisms of Action of Cimicifugae Rhizoma in the Treatment of Acute Pneumonia
Published 2024-12-01“…Jing Zhu,1 Yiming Huang,1,2 Chao Ye,3 Xiaoxia Deng,1,2 Yuxuan Zou,1,2 En Yuan,2 Qi Chen2 1Research Center for Chinese Medicine Resources and Ethnic Minority Medicine, Jiangxi University of Chinese Medicine, Nanchang, People’s Republic of China; 2School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, People’s Republic of China; 3The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, People’s Republic of ChinaCorrespondence: Jing Zhu, Research Center for Chinese Medicine Resources and Ethnic Minority Medicine, Jiangxi University of Chinese Medicine, Nanchang, People’s Republic of China, Tel +86-13755654318, Email 277836041@qq.comObjective: The main objective of this study was to elucidate the effector material basis of Cimicifugae Rhizoma (CR) for the treatment of acute pneumonia (AP) and to explore the potential mechanisms underlying the anti-AP effects of these active components in a lipopolysaccharide (LPS)-induced inflammation model of lung epithelial cells.Methods: Chemical components were identified using ultra-performance liquid chromatography-quadrupole-time-of-flight tandem mass spectrometry (UPLC-TOF-MS), and a CR component library was subsequently established based on a combination of databases and available literature. …”
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CHANGES IN THE MOLECULAR GENETIC PROFILE OF INNATE IMMUNE MOLECULES IN INDIVIDUALS WHO HAVE HAD COVID-19 DISEASE
Published 2019-08-01“…To study characteristics of expression and genetic factors of innate immunity in patients who have had COVID-19. Materials and methods. Material (scrapings from the mucous membranes and venous blood) from 148 patients was studied. …”
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Resistome, virulome, anti-defense mechanisms, and prophages in Helicobacter pylori strains in Asia
Published 2025-09-01“…The 191 H. pylori genomes harbor 20,626 virulence factors (VFs) that belong to the adherence, effector delivery system, motility, exotoxin, immune modulation and stress survival. …”
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Dendritic cells and type I and II interferon production in the local microenvironment of sinonasal tumors
Published 2024-09-01“…The subpopulations of dendritic cells and their functional potential determined by endogenous interferon status in tumor microenvironment is an important stage in tumor-specific T-lymphocytes effector reactions development. In this regard, understanding the patterns of sinonasal neoplasms immune cells changes is important in the context of the search for biomarkers of the tumor process which may open up new opportunities for targeted therapy. …”
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Development of in vitro laboratory models of the tumor immune microenvironment to evaluate quality parameters and specific efficacy of the dendritic cell vaccine
Published 2023-02-01“…The subpopulation composition of effector T-lymphocytes was determined by flow cytometry.Results. …”
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The Junction of Allergic Inflammation and Atherosclerosis: Pathways and Clinical Implications—A Review
Published 2025-06-01“…<b>Material and Method</b>: A literature search was conducted in PubMed, Google scholar; ScienceDirect, Scopus, and studies published between 2014–2024 were taken into consideration. …”
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The clinicopathological implications of serum IL-33 and sST2 as cancer biomarkers: A narrative review
Published 2025-05-01“…Conversely, it can also bolster anti-tumor immunity by recruiting and activating immune effector cells. IL-33 plays a role in multiple aspects of cancer biology, such as promoting immune evasion, tumor growth, and metastasis. …”
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Pathomorphological analysis of the qualitative composition of the inflammatory infiltrate around the pilosebaceous unit of the scalp in perifolliculitis capitis abscedens et suffod...
Published 2025-04-01“…The aim of the work is to investigate the peculiarities of the location and number of CD20+, CD3+ cells and their populations of CD4+ / CD8+ T-lymphocytes of the inflammatory infiltrate around the pilosebaceous unit of the scalp in PCAS. Materials and methods. In the work, the material of 12 male patients with a diagnosis of undermining abscessing perifolliculitis of the head (Hoffman’s disease), aged from 20 to 51 years, the average age was 35.50 ± 11.54 years, and 5 samples of clean resection edges (conditional norm) of benign nevi of the scalp were examined. …”
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Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production
Published 2025-12-01“…Antibodies used for cancer therapy are monoclonal IgGs, but tumor-targeting IgE antibodies have shown enhanced effector cell potency against cancer in preclinical models. …”
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Topical TLR7 agonist and radiotherapy in patients with metastatic breast cancer
Published 2025-04-01“…No post-treatment activation of immune-effector functions was observed in stable and progressing lesions.Conclusions Our findings support the safety and clinical efficacy of combining topical IMQ with local RT for recurrent breast cancer, with evidence of local and occasional systemic antitumor activity.Trial registration number NCT01421017.…”
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Expression characteristics and transcriptional regulation analysis of VlCKX5 gene in grape
Published 2025-01-01“…. × V. labrusca L.) as the experimental material. The young berries were treated with 10 mg·L-1 of cytokinin-like growth regulator CPPU 5 days after anthesis. …”
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Microbead‐based synthetic niches for in vitro expansion and differentiation of human naïve B‐cells
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