Extracellular Vesicles with Possible Roles in Gut Intestinal Tract Homeostasis and IBD by Xin Chang, Shu-Ling Wang, Sheng-Bing Zhao, Yi-Hai Shi, Peng Pan, Lun Gu, Jun Yao, Zhao-Shen Li, Yu Bai

“…Various studies have found that the dysfunction of intestinal homeostasis contributes to the pathogenesis of inflammatory bowel disease (IBD). …”
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Clinical case of liver transplantation in a kidney transplant recipient with hepatocellular cancer and сoronary artery disease by A. V. Shabunin, Z. A. Bagatelia, P. A. Drozdov, A. G. Komarova, S. A. Bliznyuk, G. S. Michailyants, E. Yu. Astapovich, S. A. Astapovich, V. A. Tsurkan, Yu. I. Mitchenko, P. E. Pazenko

“…Our treatment experience has shown the effectiveness and necessity of a multidisciplinary approach, early diagnosis, therapy modification during transplantation and further treatment of patients with end-stage multiple organ dysfunction.…”
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P-96 LONG-TERM PIOGLITAZONE TREATMENT AND LIVER STIFFNESS IN MASLD PATIENTS: INSIGHTS FROM A MULTICENTRIC STUDY by Mario Guimarães Pessoa, ISABEL VELOSO ALVES PEREIRA, Patricia Momoyo Yoshimura Zitelli, Mísia Joyner de Sousa Dias Monteiro, Claudia Couto, Juliana Souza de Oliveira, Ana Beatriz Souza de Oliveira, José Tadeu Stefano, Renato Altikes, Ana Luiza Gomes Reis, Ana Carolina Ferreira Netto Cardoso, Cláudio de Figueiredo Mendes, Lais Arrivabene Barbieri, Nathalie C. Leite, Cristiane A. Villela-Nogueira, Claudia P Oliveira

“…This study aims to evaluate whether sustained consumption of pioglitazone over 12-24 months can improve liver stiffness in individuals diagnosed with biopsy- proven metabolic dysfunction-associated steatohepatitis (MASH). Patients / Materials and Methods: Retrospective data from 56 MASLD patients who received pioglitazone treatment for 12-24 months (15-30 mg daily) were gathered from three public hospitals in Brazil. …”
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Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics by Ping Wang, Francesco Petrella, Luca Nicosia, Massimo Bellomi, Stefania Rizzo

“…Finally, we discuss theranostic imaging for stem cells transplantation for liver dysfunction and future opportunities afforded by theranostic imaging.…”
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Development and Validation of Tadalafil Determination in Human Plasma by HPLC-MS Method by D. S. Bogdanova, T. N. Komarov, I. E. Shohin, E. S. Melnikov, O. A. Miskiv, Yu. V. Medvedev

“…Tadalafil is a drug used to treat erectile dysfunction. For the quantitative determination of tadalafil in human plasma are used methods of high performance liquid chromatography with ultraviolet and tandem mass spectrometric detection, during the analytical part of pharmacokinetic studies. …”
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Unusual Benign Middle Ear Tumors: How Does the Presentation Differ from Otitis Media? by Krutika Sonvane, Navnit Makwana, Rahul Gupta, Hardik Patel, R G Aiyer

“…As these tumors are histologically benign, they are only locally destructive causing vestibular/facial dysfunction. Materials and Methods: In this case series, we have included 5 cases of rare middle ear tumors, who presented to our hospital in period of 2020-2023. …”
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Association Between Skin Findings and Ocular Signs in Rosacea by Francisco Lucero Saá, Federico Cremona, Pablo Chiaradia

“…Objectives:To report the most frequent signs in ocular rosacea and evaluate their association with skin findings.Materials and Methods:Fifty-one patients diagnosed with rosacea by a trained dermatologist were evaluated by an ocular surface specialist. …”
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Research progress on the microecological strategies of root caries management by WU Lijing, TAO Yiwei, ZENG Bo, CAI Yanling

“…Root caries is primarily caused by core microbiome-induced dysbiosis and has multiple risk factors, including gingival recession, root surface exposure, and salivary dysfunction. The traditional preventive measures and treatments such as fluoride, mineralizing agents, and restorative materials, are unable to restore or maintain oral microecological homeostasis. …”
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Risk factors, criteria and biomarkers of acute kidney injury in the perioperative period by M. I. Neimark, A. A. Burenkin, S. E. Elchaninova, V. M. Raevsky, I. D. Raikin

“…The  study of both biomarkers that surpass creatinine and diuresis in the timing and accuracy of detecting kidney damage/dysfunction, as well as tools for  a comprehensive assessment and risk stratification of perioperative acute kidney injury, have not yet been completed with evidence-based conclusions.  …”
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VESSEL DISEASES IN INFECTION COVID-19 IN PATIENTS WITHFATAL CASES by Зинаида Александровна Хохлова, Раиса Алексеевна Гилева, Татьяна Васильевна Середа, Юлия Михайловна Кириллова

“…Nearly all of the patients have got the comorbid conditions: hypertensive disease, diabetes mellitus, the chronic nervous system disorders (cerebral dysfunction, cerebrovascular disease, encephalopathy), obesity, chronic heart disease and others. …”
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Challenges of Diagnosis and Treatment Choice in Riedel‘s Fibrosing Thyroiditis: Clinical Case Examples by M. G. Davydovich, R. V. Ipaeva, K. P. Derevyanko

“…Riedel’s fibrosing thyroiditis can be reluctant to diagnosis due to asymptomatic thyroid dysfunction, the lack of strict radiological diagnostic criteria and rarity in clinical practice. …”
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Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites by Yu. V. Khoronko, M. A. Kozyrevskiy, A. V. Dmitriev, A. A. Volokhova, G. Yu. Spiridenko, K. R. Bogomolova

“…No variceal bleeding was observed in cohort 2, with 7 patients having the portosystemic shunt dysfunction.Conclusion. The TIPS procedure is justified in cirrhotic PH patients with RA for reducing the mortality rate in a one year follow-up.…”
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Design and experimentation of the nested pneumatic soft actuator for hand exoskeleton by Yi Lv, Zaiming Geng, Hao Wu, Yigang He, Zhongming Lv

“…Abstract Frequent repetitive manual tasks in the manufacturing industry have contributed to a rise in hand motor dysfunction, negatively affecting both health and work efficiency. …”
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Neuropsychiatric Manifestations of Lyme Disease: A Literature Review of Psychiatric and Cognitive Impacts by Gabija Šegždaitė, Odeta Aliukonytė, Kamilė Pociūtė

“…This paper examines the connection between Lyme disease and neuropsychiatric outcomes to improve diagnosis and treatment.Materials and Methods: The PubMed database was searched for scientific literature sources. …”
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Methemoglobinemia in a child with congenital epidermolysis bullosa by Ya. A. Lezhepekova, K. V. Pshenisnov, Y. S. Aleksandrovich

“…Methemoglobinemia is a rather rare cause of hypoxemia and hypoxia, however, with a severe course of the disease and an increase in the concentration of methemoglobin in the blood of more than 20 %, this can cause the development of multi-organ dysfunction and death.The objective was to descript the case of methemoglobinemia in a child with congenital epidermolysis bullosa with the use of a combined drug containing benzocaine.Materials and methods.  …”
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Therapeutic Effects of Rosemary Leaf Extract on Liver and Kidney Parameters of Rats Treated with Cypermethrin by Somda, Marius K.

“…Conclusion: Rosemary extract ameliorated cypermethrininduced hepatic and renal dysfunction, likely due to its antioxidant and anti-inflammatory properties, highlighting its potential as a therapeutic adjunct against pesticide toxicity…”
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The clinical signifi cance of urethral sphincter hyperkinesis in the treatment of benign prosta???? c hyperplasia by I. I. Belousov

“…Exactly this fact, that these patients had urethral sphincter dysfunction in 14.5% of cases made for poor effect of surgical treatment of BPH. …”
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Morphological rearrangement of the metabolic link of the microcirculatory bed of guinea pigs lungs after sensitization with ovalbumin by S. S. Popko

“…The aim is to study the morphological changes in the vessels of the metabolic link of the microcirculation in the lungs of guinea pigs sensitized with ovalbumin. Materials and methods. We have studied the lungs of 48 guinea pigs, using histological and morphometric methods, under conditions of experimental ovalbumin-induced allergic inflammation, simulated by three-time subcutaneous sensitization and subsequent 8-day intranasal inhalation of ovalbumin. …”
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Acute Kidney Injury Secondary to Trauma Brain Injury (TBI) and the Role of Angiotensin-1-7 by Mehdi Jahantigh, Abolfazl Parsi-Moud, Hamede Damani, Mohammad Ali Mirshekar, Ilia Mirzaei, Hossein Bagheri, Elham Shoghi, Tahereh Safari

“…Results: Traumatic brain injury induced significant renal dysfunction, evidenced by elevation in serum Cr levels in TBI group compared to vehicle group, P<0.05. …”
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Deranged liver among Sudanese Patients with Dengue Virus Infection in Port Sudan Teaching Hospital by Bashir Abdrhman Bashir Mohamed

“…ConclusionThis study demonstrated that hepatic dysfunction may be attributed to dengue virus infection which evident by prolongation in PT and PTT as well as hypofibrinogenemia and factor deficiencies.…”
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