The impact of chronic heart failure on heart remodeling in patients with atrial fibrillation by V. А. Lysenko, V. V. Syvolap

“…AF patients with signs of CHF had decreased LV EF (55.58 ± 14.65 % vs. 65.44 ± 10.87 %; P = 0.006), systolic velocity of the medial fibrous ring of the mitral valve S (6.92 ± 2.41 cm/s vs. 8.40 ± 2.03 cm/s; P = 0.015), and significantly higher values of TEI RV (0.58 ± 0.16 c. u. vs. 0.48 ± 0.11 c. u.; P = 0.011), but decreased TAPSE values (16.22 ± 4.60 mm vs. 19.54 ± 5.00 mm; P = 0.067), indicating more pronounced systolic dysfunction of both ventricles. Conclusions. Comorbidity of CHF and AF in patients is accompanied by the increased percentage of eccentric hypertrophy (49 %; P = 0.027), more pronounced systolic dysfunction of the left and right ventricles, increased LVEDP, PCWP, systolic pressure in the pulmonary artery, dilation of the inferior vena cava.…”
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Рrediction risk factors of gastroesophageal reflux disease in children and adolescents with chronic gastroduodenal pathology by L. M. Boiarskа, К. А. Ivanova

“…The main risk factors of its development are acid-peptic factor, Н.pylori, the autonomic nervous system dysfunction, rapid growth, heredity, burdened perinatal history, dysplasia of connective tissue structures (DCTS), environmental factors and lifestyle. …”
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Clinical Features and Inhospital Outcomes of Takotsubo (Stress) Cardiomyopathy: Ten Years’ Experience from a Tertiary Care Center in South India by Amit Mandal, John Jose, Oommen K. George, Paul V. George, Viji Samuel Thomson, George Joseph

“…Background: Takotsubo cardiomyopathy is a syndrome which is characterized by transient regional systolic dysfunction, principally, of the left ventricle (LV), mimicking myocardial infarction (MI), but in the absence of angiographic evidence of obstructive coronary artery disease or acute plaque rupture. …”
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Clinical efficacy of gliclazide with modified release after myocardial infarction in patients with concomitant type 2 diabetes by N. S. Mykhailovska

“…Objective: to study the effectiveness of gliclazide modified release in patients with Q- myocardial infarction with concomitant type 2diabetes mellitus by its effect on the clinical course of the disease, glucometabolic control and humoral parameters during 12 months of observation. Materials and Methods: we examined 99 patients with Q- myocardial infarction with metabolic syndrome and concomitant type 2diabetes mellitus, 52 men (52.53%) and 47 women (47.47%), average age (62,9 ± 2, 05) years. …”
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Optimizing the treatment for gastroesophageal reflux disease in young people: the role and place of rebamipide by I.M. Skrypnyk, I.M. Gorodnytska, G.S. Maslova, B.M. Fylenko

“…Objective: to evaluate the effect of rebami­pide on the restoration of the esophageal protective barrier in the presence of erosive or non-erosive forms of gastroesophageal reflux disease in young patients. Materials and methods. Thirty young patients with GERD aged 18 to 45 years were examined. …”
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Analysis of probable predictors of aggressive multiple sclerosis by N. N. Spirin, E. V. Kiseleva, N. N. Spirina

“…Objective: to study the probable laboratory predictors of aggressive multiple sclerosis.Materials and methods. Antibodies to myelin oligodendrocyte glycoprotein (MOG), antibodies to thyroperoxidase and markers of endothelial dysfunction in blood serum were determined in patients with multiple sclerosis (MS). …”
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Interrelationship between endotoxicosis and syndrome of intraabdominal hypertension in pathogenesis of abdominal sepsis. by N. A. Valiyev

“…Studying of mutual role of the main pathogenetic factors of abdominal sepsis – the inflammation origin and intraabdominal hypertension, from the one side, endotoxicosis and the abdominal compression syndrome (ACS), from the other side. Materials and methods. Into the investigation 196 patients with abdominal sepsis were included, in whom after the certain preliminary preparation the operative procedure was done. …”
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Advances in diagnostic imaging of the glial lymphatic system in Alzheimer's Disease by Feiyue Mi, Xiaoyan Yang, Xueyan Huang, Gaoqiang Xu, Dongfeng Pan, Changyin Yu

“…Dysfunction in this system can result in the abnormal accumulation of amyloid-beta (Aβ) and tau proteins, leading to cognitive impairments. …”
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Rational Fabrication of Copper Nanoclusters and In Vitro Study of Antioxidant Property by Jiale Zhang, Xiao Liang, Mijia Yan, Qiuhong Zhang, Hangrong Chen

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Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus by Olga Leonidovna Barbarash, Aleksey Nikolaevich Sumin, Olesya Evgen'evna Avramenko, Anastasia Vyacheslavovna Osokina, Aleksey Vladimirovich Veremeev

“…Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. …”
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The Emerging Roles of Vacuolar-Type ATPase-Dependent Lysosomal Acidification in Cardiovascular Disease by Yan-Yan Chen, Cai-Xia Liu, Hai-Xin Liu, Shi-Yuan Wen

“…By controlling the pH within lysosomes, V-ATPase contributes to overall cellular homeostasis, helping to maintain a balance between the degradation and synthesis of cellular components. Dysfunction of V-ATPase impairs lysosomal acidification, leading to the accumulation of undigested materials and contributing to various diseases, including cardiovascular diseases (CVDs) like atherosclerosis and myocardial disease. …”
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A low-cost simulation model for priapism detumescence training by Sachin Garach, Hanlie Dreyer, Ahmed Adam, Abdullah Laher

“…Ischaemic priapism is a urological emergency requiring prompt intervention to prevent complications such as erectile dysfunction. Because of its low incidence, opportunities for hands-on training are limited, particularly in resource-constrained settings. …”
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Advancements in State-of-the-Art Ankle Rehabilitation Robotic Devices: A Review of Design, Actuation and Control Strategies by Asna Kalsoom, Muhammad Faizan Shah, Muhammad Umer Farooq

“…Neurological disorders like stroke are one of the main causes of motor dysfunction and gait function disabilities in humans. …”
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Semiology and clinical development of cystopathy in patients with type 2 diabetes mellitus by Igor Valentinovich Kuz'min, Natalya Olegovna Shabudina, A S Al'-Shukri

“…To investigate clinical peculiarities of cystopathy in correlation with duration of type 2 diabetes mellitus (T2DM). Materials and Methods. 70 patients with T2DM (26 male and 44 female; mean age 63.3?…”
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Early diagnosis and treatment of splenic artery steal syndrome after liver transplantation by А. А. Kirshin, А. Yu. Teregulov, A. R. Kirshina

“…SASS remains a severe vascular complication of LTx, which can lead to graft dysfunction and possible loss. Timely detection and treatment prevent severe consequences for the liver recipient.…”
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The Role of Leu-Enkephalin Synthetic Analogue in Regulation of Systemic Inflammatory Response and Prevention of ARDS in Severe Combined Injury by A. Y. Ryzhkov, V. V. Antonova, R. A. Cherpakov, E. A. Chernevskaya, A. K. Shabanov, D. A. Ostapchenko, M. A. Magomedov, O. A. Grebenchikov

“…To study the effect of ley-enkephalin synthetic analogue on the dynamics of inflammatory response markers and organ dysfunction in patients with severe combined trauma.Materials and methods. …”
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TRANSFORMING GROWTH FACTOR 1 IN CHILDREN OF EARLY AGE WITH LIVER TRANSPLANTATION by R. M. Kurabekova, O. P. Shevchenko, O. M. Tsiroulnikova, I. E. Tsiroulnikova, G. A. Olefirenko, S. V. Gautier

“…A correlation (r = –0,23, p < 0,05) between level of TGF-β1 prior to transplantation and the development of graft dysfunction was observed: in recipients with graft dysfunction (16 cases) cytokine level prior to surgery was lower (p = 0,047) than in other recipients.Conclusion. …”
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Experimental faecal peritonitis alters response to 5-hydroxytryptamine in mesenteric lymphatic vessels by A. A. Egorova, E. A. Avramenko

“…In experimental faecal peritonitis, alterations in lymphatic vessels are reminiscent of those in blood vessels. Endothelial dysfunction disturbs the response of lymphatic vessels to 5-HT.…”
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Heart Rate Variability in Young Adults with Bronchial Asthma with and without Previous COVID-19 Infection: A Cross-sectional Study by Gunaseelan Deivendran, Thamarai Selvi Kanagaraj, Bhavisha Sreenivasan Leelabai, Nalini Jayanthi, Saravanan Ayyavoo

“…Aim: To compare HRV parameters between young adult bronchial asthma patients with and without a history of COVID-19, and assess the extent of autonomic dysfunction attributable to COVID-19. Materials and Methods: This cross-sectional study included 100 bronchial asthma patients aged 20-40 years, equally divided into two groups based on COVID-19 history. …”
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Strategy for prophylactic application of peripheral va-ecmo in transplantation involving expected extremely prolonged ischemia time by V. N. Poptsov, V. M. Zakharevich, E. A. Spirina, A. I. Skokova, A. K. Solodovnikova, A. S. Ignatkina, A. A. Kuznetsova, G. B. Glinkin

“…Heart transplantation (HT) with extremely prolonged (>6 hours) graft ischemia is associated with severe cardiac graft dysfunction. The high efficiency of prophylactic (preoperative initiation) veno-arterial extracorporeal membrane oxygenation (VA-ECMO) to prevent severe hemodynamic disorders during cardiac surgery has been demonstrated. …”
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