Surgical Remodeling of the Left Ventricle in Patients with Post-Infarction Dilation and Heart Failure by P. V. Chernyavsky, M. Kh. Mazanov, I. A. Argir, N. M. Bikbova, S. Yu. Kambarov, M. A. Sagirov, A. V. Dublev, A. V. Timerbaev, N. I. Kharitonova

“…The absence of readmission to the hospital due to recurrent angina pectoris, mitral valve dysfunction and progression of heart failure (HF) was 72% among surviving patients.CONCLUSION Surgical remodeling reduces the volume of the dilated left ventricle and restores its elliptical shape in patients with CAD after anterior myocardial infarction. …”
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Morphological features of changes in peripheral olfactory structures in SARS-COV-2 coronavirus infection by I. S. Shponka, V. I. Popovych, О. М. Usova, O. O. Bondarenko, Yu. V. Haman, H. Z. Shchuruk

“…The aim is to identify the morphological features of olfactory structural elements in patients with coronavirus disease (COVID-19) for a better understanding of the mechanisms of olfactory disorders development in coronavirus infection. Materials and methods. The basis of the work is a retrospective analysis of autopsy material, namely the mucous membrane of the upper parts of the nasal cavity (olfactory epithelium) and olfactory bulbs of nine deceased (4 women and 5 men) aged from 53 to 79 years with a laboratory-confirmed diagnosis of COVID-19 and anosmia in anamnesis. …”
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Rationale and population-based prospective cohort protocol for the disadvantaged populations at risk of decline in eGFR (CO-DEGREE) by Antonio Bernabe-Ortiz, Neil Pearce, Hans Kromhout, Pablo Perel, Liam Smeeth, Cristina O’Callaghan-Gordo, Jason Glaser, Kristina Jakobsson, Dorothea Nitsch, Ben Caplin, Nalika Gunawardena, Adeera Levin, Vidhya Venugopal, Marvin Gonzalez-Quiroz, Sophie Hamilton, Cristina O'Callaghan Gordo, Rajiv Saran, Ricardo Correa-Rotter, Ajay Singh, Giuseppe Remuzzi, Emmanuel Burdmann, Rick Johnson, Phabdheep Kaur, Pronpimolk Kongtip, Magdalena Madero Rovalo, Moffat Nyirenda, Dorairaj Prabhkaran, Narayan Prasad, Nalika Gunawardenan

“…In this paper, we propose a standardised minimum protocol for cohort studies in high-risk communities aimed at investigating the incidence of, and risk factors for, early kidney dysfunction.Methods and analysis This generic cohort protocol provides the information to establish a prospective population-based cohort study in low-income settings with a high prevalence of CKDu. …”
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CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 2 by I. D. Strazhesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, N. V. Sharashkina, O. Yu. Isaykina, V. A. Vygodin, S. A. Boytsov

“…Such lesions include: arterial wall thickening, increased rigidity, endothelial dysfunction development. However, the role of traditional CVD risk factors in the development of individual arterial wall lesions in CVD-free people is understudied. …”
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Algorithm for the provision of comprehensive psychotherapeutic support to women experiencing neuropsychiatric symptoms during rehabilitation following the treatment of malignant ne... by D. V. Blinov, A. G. Solopova, E. E. Achkasov, E. S. Akarachkova, O. V. Kotova, S. A. Akavova, V. N. Galkin, G. K. Bykovshchenko, L. N. Sandzhieva, D. I. Korabelnikov, T. A. Blbulyan, D. A. Petrenko, A. Yu. Vlasina

“…Chronic pain syndrome, distress, anxiety and depression, decreased self-esteem, sexual dysfunction and social maladjustment reduce quality of life (QoL) and require psychotherapeutic support.Objective: to create an algorithm for the provision of comprehensive psychotherapeutic support during rehabilitation following the treatment of reproductive system MNs and to evaluate its effect on QoL indicators in women with neuropsychiatric disorders.Material and methods. …”
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The Influence of Non-Alc oholic Fatty Liver Disease on Indicators of Arterial Stiffness and Risk of Cardiovascular Complications in Patients with Arterial Hypertension by M. E. Statsenko, A. M. Streltsova, M. I. Turovets

“…Comorbid patients have pronounced endothelial dysfunction, which is confirmed by a significant increase in the post-occlusion rate of the pulse wave. …”
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Effect of visceral obesity on main artery elasticity and vascular age in patients with hypertension, obesity, and type 2 diabetes by M. E. Statsenko, M. V. Derevyanchenko

“…To assess the effect of visceral obesity on main artery elasticity and vascular age in patients with hypertension (HTN), obesity, and type 2 diabetes (T2D).Material and methods. A total of 320 patients with stage II-III HTN aged 4570 years were divided into 4 groups: isolated HTN (group 1), HTN and obesity (group 2), HTN, obesity and T2D (group 3), HTN and T2D without obesity (group 4). …”
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Neuroprotective Effects of Inhaled Xenon for Sedation Compared With Propofol Intravenous Sedation in Severe Ischemic Stroke by O. A. Grebenchikov, A. K. Evseev, V. V. Kulabuchov, A. N. Kuzovlev, S. S. Petrikov, G. R. Ramazanov, Sh. Gh. Khusainov, R. A. Cherpakov, A. K. Shabanov, A. I. Spichko

“…The paper presents the effect of inhaled xenon for sedation in patients with severe ischemic stroke on the level of consciousness and severity of neurological disorders, and also shows its effect on S100B protein, a marker for blood brain barrier damage.AIM OF STUDY To evaluate the effect of inhaled xenon for sedation in comparison with propofol intravenous sedation on the dynamics of the level of consciousness, the severity of neurological dysfunction and changes in the concentration of astroglial-derived S100B protein in severe ischemic stroke.MATERIAL AND METHODS The research was conducted on two groups of patients comparable in age, gender, comorbid background, as well as the severity of the underlying disease. …”
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What is the role of non-surgical clinicians in the assessment and management of degenerative cervical myelopathy? – Insights from the RECODE-DCM peri-operative rehabilitation incub... by Rohil V. Chauhan, Andreas K. Demetriades, Timothy F. Boerger, Justin M. Lantz, Caroline Treanor, Sukhvinder Kalsi-Ryan, Vishal Kumar, Lianne Wood, Joshua Plener, Nicky Wilson, Maryse Fortin, Carlo Ammendolia, Annalena Paus, Rana S. Dhillon, Benjamin Davies, Michael G. Fehlings, David B. Anderson

“…While predictors of postoperative outcomes, such as disease severity, gait dysfunction and smoking, are known, evidence on preoperative optimization and prehabilitation remains limited. …”
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Impact of long-distance (up to 3.500 km) deceased donor liver transportation on cold ischemia time, initial graft function and transplant outcomes by A. I. Sushkov, K. K. Gubarev, V. L. Vinogradov, V. S. Rudakov, D. S. Svetlakova, A. A. Fedyunin, M. Krstich, A. I. Zakhlevnyy, A. I. Artemiev, S. E. Voskanyan

“…Despite the tendency to increases in the incidence of the early allograft dysfunction (6/41 in group 1, 9/31 in group 2; p = 0.155), primary graft non-function (1/41 in group 1, 3/31 in group 2; p = 0.308), and the graft loss incidence during the first 6 weeks (4/41 in group 1; 7/31 in group 2; p = 0.189), these differences did not reach the statistical significance.Conclusion. …”
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Predictors of rethrombosis and death in patients with COVID-19 after lower limb arterial thrombectomy for acute ischemia by M. V. Afonkina, O. Yu. Martynova, S. S. Nazarova, A. V. Korotkikh, O. V. Lebedev, S. V. Artyukhov, O. Sh. Mukhtorov, R. Yu. Lider, Sh. Van, T. Sh. Ramazanova, L. V. Roshkovskaya, A. S. Zharova, V. S. Trishin, G. Yu. Kargatova, E. Ya. Yakhnis, A. A. Pivovarov, M. A. Khetagurov, V. M. Unguryan, A. N. Kazantsev, Yu. B. Belov

“…In 65,6% of patients, a death was established due to multiple organ dysfunction. Among them, limb amputation was performed in 103 patients. …”
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Safety and Effectiveness of Pharmacologic Conversion of Atrial Fibrillation and Flutter: Results of Multicenter Trial. Part II: Assessment of Safety by N. Yu. Mironov, Yu. A. Yuricheva, V. V. Vlodzyanovskiy, S. F. Sokolov, Kh. M. Dzaurova, S. P. Golitsyn, Yu. V. Shubik, M. V. Berman, M. M. Medvedev, A. E. Rivin, D. S. Parkhomchuk, A. E. Barybin, D. А. Balandin, R. E. Batalov, D. V. Terekhov, I. V. Evstifeev, I. R. Kildeev, O. V. Pyataeva, S. A. Zenin

“…We aimed to assess safety and effectiveness of class III antiarrhythmic drug Refralon for conversion of atrial fibrillation (AFib) and flutter (AFl) in post-registration trial and to compare data of primary center (National medical research center in cardiology) with data of other hospitals.Material and Methods. We performed retrospective cohort study in 727 patients (451 enrolled in primary center and 276 enrolled in other hospitals) admitted between June 24, 2014 and June 24, 2019. …”
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Brown adipose tissue: a potential therapeutic target for preventing cardiovascular disease in metabolic disorders by Tamara Egan Beňová, Matúš Sýkora, Katarína Ondreják Andelová, Veronika Farkašová, Marek Lepáček, Marta Šoltésová Prnová, Pavel Babál, Dávid Janko, Natália Andelová, Miroslav Ferko, Barbara Szeiffová Bačová

“…Echocardiography revealed diastolic dysfunction in T2D rats, which was attenuated by Cemtirestat. …”
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Intestinal Oxygenotherapy of Critical Conditions by V. A. Mazurok, A. S. Golovkin, I. I. Gorelov, A. E. Bautin, I. N. Menshugin, O. A. Slivin, D. S. Tarnovskaya, V. V. Ivanov, V. G. Nikiforov, K. A. Morozov, A. O. Marichev

“…To determine the effect of intestinal oxygenotherapy in patients with enteropathies of critical conditions on the dynamics of biomarkers of the intestinal wall permeability and ischemia.Materials and methods. An open prospective descriptive study of 12 critically ill patients (7 adults, 5 children) with multiple organ failure and evident or saspected dysfunction of the gastrointestinal tract. …”
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ENDOCRINE DISFUNCTION IN WOMEN WITH PRE-ECLAMPSIA AND ALIMENTARY OBESITY by A. N. Rymashevskii, S. S. Tumanyan, E. M. Frantsiyants, S. V. Tumanyan

“…Stimulating the RAAS aggravates the inflammatory response and endothelial dysfunction in women with PE and AO. Elevated concen-trations of leptin in these women have a direct damaging impact on the kidney tubules.…”
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COMPREHENSIVE MARKETING STUDY OF THE RUSSIAN PHARMACEUTICAL MARKET DRUGS FOR PREVENTION AND TREATMENT OF DISEASES OF THE THYROID GLAND by V. I. Zvereva, O. A. Semkina, E. I. Gribkova

“…Medicinal plant raw materials is a promising source for the development of drugs used for the prevention and treatment of thyroid dysfunction. …”
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Integrating the Interleukins in the Biomarker Panel for the Diagnosis and Prognosis of Patients with Acute Coronary Syndromes: Unraveling a Multifaceted Conundrum by Amalia-Stefana Timpau, Egidia-Gabriela Miftode, Irina-Iuliana Costache-Enache, Antoniu-Octavian Petris, Ionela-Larisa Miftode, Ivona Mitu, Radu-Stefan Miftode

“…GDF-15 is representative of a multivalent biomarker involved in inflammation, heart failure, and renal dysfunction.…”
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Exercise and the Aging Endothelium by Saeid Golbidi, Ismail Laher

“…The endothelium plays a critical role in the maintenance of cardiovascular health by producing nitric oxide and other vasoactive materials. Aging is associated with a gradual decline in this functional aspect of endothelial regulation of cardiovascular homeostasis. …”
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Application of Damage Control tactics in the treatment of patients with generalized peritonitis and septic shock by A. Е. Demko, S. A. Shlyapnikov, I. M. Batyrshin, A. V. Оsipov, J. S. Оstroumova, D. S. Sklizkov, D. V. Fomin

“…The role and place of the Damage control technique in this category of patients remain debatable.The OBJECTIVE was to analyze the use of tactics of staged surgical treatment in patients with peritonitis and septic shock.METHODS AND MATERIALS. On the base of the Saint-Petersburg I. I. …”
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Effect of Cananga odorata modulates cholinergic, purinergic enzymes, and elevates antioxidant markers in diabetes-induced cognitive disorder rat brain by Jamiyu A. Saliu, Olajide R. Ojo, Idowu S. Oyeleye, Ganiyu Oboh

“…Introduction: In the folklore of Chinese traditional medicine, therapeutic materials like Cananga odorata have several attributes that ameliorate non-communicable diseases. …”
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