Dynamic Electroneurostimulation in Rehabilitation: a Prospective Randomized Study of 60 Patients after Surgical Treatment of Colorectal Malignancies by Victor A. Drobyshev, Lubov A. Shpagina, Andrey A. Vlasov, Marina V. Umnikova, Tatyana M. Smarzh

“…To evaluate the effectiveness of incorporating dynamic electroneurostimulation in the rehabilitation of patients after surgicaltreatment for colorectal cancer to correct pain syndrome, autonomic dysfunction and quality of life indices. MATERIAL AND METHODS. 60 male and female patients aged between 35 and 65 with a verified diagnosis of the colon and rectummalignant neoplasms after surgical treatment were examined in the conditions of the outpatient oncological care center at the StateMedical Institution “City Clinical Hospital No. 2” (Novosibirsk). …”
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Pd Icosahedral Nanoparticles Promote Skin Wound Healing by Enhancing SP1-HBEGF Axis-Mediated Keratinocytes Proliferation by He F, Li M, Zhao H, Zhao H, Meng X, Zhang Y, Tang Y, Huang H, Li J, Xie H, Wang B

“…Fanping He,1– 3,* Mengfan Li,4,* Han Zhao,1,3 He Zhao,1,3 Xin Meng,1,3 Yiya Zhang,1,3,5 Yan Tang,1,3,5 Hongwen Huang,4,6 Ji Li,1,3,5 Hongfu Xie,1,3 Ben Wang1,3,5 1Department of Dermatology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 2Department of Plastic and Reconstructive Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 4College of Materials Science and Engineering, Hunan University, Changsha, Hunan, 410082, People’s Republic of China; 5National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People’s Republic of China; 6Shenzhen Research Institute of Hunan University, Shenzhen, Guangdong, 518055, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ben Wang, Email wangben@csu.edu.cn Hongfu Xie, Email xiehongfu@csu.edu.cnIntroduction: Impaired wound healing leads to compromised cutaneous barrier and dysfunction, which still remains a challenging problem. …”
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STUDY OF LONG-TERM CLINICAL AND PATHOGENETIC EFFECTS OF FAVIPIRAVIR-BASED ANTI-VIRAL DRUG IN PATIENTS WITH METABOLIC SYNDROME IN POST-COVID PERIOD by O. A. Radaeva, L. A. Balykova, K. Ya. Zaslavskaya, A. V. Taganov, P. A. Bely, Yu. A. Kostina, E. V. Negodnova, S. V. Mashnina, D. D. Bessheinov, M. S. Iskandyarova, V. V. Eremeev, N. M. Chumakov

“…It helps to correct the pro-inflammatory vector of the immune response at the post-COVID stage and, accordingly, reduces the risk of progression of atherosclerosis, transient cerebrovascular accidents with a cognitive decline, an endothelial dysfunction, and can be considered a secondary prevention of life-threatening cardiovascular complications.…”
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Protocol for the development of Polish clinical guidelines for the management of patients with systemic lupus erythematosus by Joanna Makowska, Brygida Kwiatkowska, Magdalena Krajewska-Włodarczyk, Bogdan Batko, Marcin Stajszczyk, Jerzy Świerkot, Zbigniew Żuber, Piotr Leszczyński, Agata Sebastian, Magdalena Władysiuk, Irena Walecka, Michał Chmielewski, Mariusz Stasiołek, Maria Maślińska

“…Left untreated or inadequately managed, SLE can lead to severe organ dysfunction, disability, and reduced quality of life. …”
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PATHOMORPHOLOGICAL DYNAMIC DUST CHANGES OF LUNG VESSELS IN KUZBASS MINERS WITH DIFFERENT WORK EXPERIENCE by Олег Иванович Бондарев, Арнольд Михайлович Сурков, Павел Алексеевич Азаров, Сергей Николаевич Филимонов

“…Hypertrophy of the muscular layer of blood vessels, perivascular fibrosis and endothelial dysfunction cause tissue and cellular changes in the vascular system of the lungs with the development of pulmonary hypertension and can serve as a marker of the pneumoconiotic (PC) process. …”
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Acute Kidney Injury in Patients with Novel Coronavirus Infection <i>COVID</i>-19 After Cardiac Surgery by G. A. Berdnikov, S. I. Rey, M. A. Sagirov, V. S. Selyaev, A. I. Kovalev, D. A. Kosolapov

“…To study the experience of using RRT and ECHC methods.   MATERIAL AND METHODS. We examined 23 patients with a confirmed diagnosis of COVID-19 who were treated in the Infectious Diseases Department of the N. …”
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CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH ISCHEMIC HEART DISEASE RESISTANT TO ACETYLSALICYLIC ACID IN PERIOPERATIVE PERIOD OF CORONARY ARTERY BYPASS GRAFT: RESULTS O... by Yu. I. Grinshtein, A. A. Kosinova, I. Yu. Grinshtein, A. V. Kovalev, V. G. Sukhovol'skiy, A. A. Savchenko

“…Cardiopulmonary bypass, COX-2 inhibitors, renal dysfunction, the inflammatory response, may be possible reasons of the ASA-resistance after CABG. …”
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Atrial fibrillation and chronic kidney disease: main clinical characteristics of patients in selected subjects of the Russian Federation by M. A. Druzhilov, T. Yu. Kuznetsova, O. Yu. Druzhilova, U. D. Arustamova, D. V. Gavrilov, A. V. Gusev

“…This emphasizes the need to optimize risk stratification, ACT and algorithms for the prevention of athero­thrombotic events, as well as the development of nephro­protective strategies to reduce the rate of progression of renal dys­function in this cohort of patients.…”
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Associations of Cardiovascular Risk Factors and Genetic Markers with Development of Arterial Hypertension in the Population of Mountain Shoriya by T. A. Mulerova, S. A. Maksimov, M. Yu. Ogarkov, O. V. Gruzdeva, A. V. Ponasenko, V. N. Maksimov, M. I. Voyevoda, E. S. Filimonov, G. V. Artamonova

“…To study the combined effect of cardiovascular risk factors and genetic markers that encode the proteins of the main components of neurophysiological systems (renin-angiotensin-aldosterone, sympathetic-adrenal systems, endothelial dysfunction) on the development of arterial hypertension among the indigenous and non-indigenous population of Mountain Shoriya.Material and methods. …”
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THE ANALYSIS OF THE PREVALENCE OF DENTAL ANOMALIES IN UZHHOROD SCHOOLCHILDREN by V.S. Melnyk, L.F. Horzov, O.Yu. Rivis, M.E. Izay

“…The purpose of the study is to analyze the prevalence of dentoalveolar anomalies in schoolchildren of Uzhgorod. Material and methods. The study involved 339 schoolchildren in Uzhgorod. …”
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ANTIHYPERTENSIVE TREATMENT WITH COMBINED DRUG OF LOSARTAN AND HYDROCHLOROTHIAZIDE by R. M. Linchak, K. M. Shumilova, A. D. Martinyuk, T. A. Gusaim, E. V. Semyonova, L. G. Zhirova, S. A. Boitsov

“…Treatment resulted in reduction of number of patients with myocardial hypertrophy (from 50% to 30%, p&lt;0.01), and of patients with diastolic dysfunction of left ventricle (from 43.3% to 30%, p&lt;0.05). …”
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Eliminating Heavy Metals from Water with Nano-Sheet Minerals as Adsorbents by Shaoxian Song

“…<br />Nano-sheet molybdenite is a novel two-dimensional material with single or several layers of MoS2 sheets. …”
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Mixed connective tissue disease with juvenile onset: results of a retrospective single-center study by M. I. Kaleda, I. P. Nikishina, A. N. Latypova, N. N. Yudkina, Zh. G. Verizhnikova, A. N. Shapovalenko, T. N. Pachkoria

“…The diagnosis is often delayed and confirmed only at an advanced stage of organ dysfunction with the development of irreversible changes.Objective: to identify a group of patients fulfilling the criteria for MCTD in an open, single-center, continuous retrospective study among anti-ribonucleoprotein (anti-RNP) antibody-positive patients and to analyze their demographic, clinical and laboratory characteristics and therapy.Material and methods. …”
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Protective role of 3-oxypyridine derivatives in rats’ steroid-induced osteoporosis associated with reduced oxidative stress and recovery of nitric oxide formation by A. P. Danilenko, K. S. Trunov, M. V. Pokrovsky, L. M. Danilenko, M. V. Korokin, O. S. Gudyrev, A. A. Khentov, N. P. Masalytina, I. A. Tatarenkova, A. V. Cherednichenko, E. V. Boeva, I. S. Koklin, E. I. Taran

“…From the point of view of the mechanisms for the implementation of pathogenetic links in the development of steroid-induced osteoporosis considered in the paper, the increased risk of the oxidative stress in osteoblasts, as well as the development of the vessels endothelial dysfunction of the microcirculatory bloodstream in the bone tissue, are of particular interest. …”
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Usefulness of the Córdoba Equation for Estimating Body Fat When Determining the Level of Risk of Developing Diabetes Type 2 or Prediabetes by Marta Marina Arroyo, Ignacio Ramírez Gallegos, Hernán Paublini, Ángel Arturo López-González, Pedro J. Tárraga López, Cristina Martorell Sánchez, Tomás Sastre-Alzamora, José Ignacio Ramírez-Manent

“…However, recent evidence suggests that the adipose tissue composition and distribution play a more critical role in metabolic dysfunction than the total body weight or body mass index (BMI). …”
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Pharmacological effects of a new soluble guanylate cyclase stimulator in experimental pulmonary arterial hypertension by V. V. Bykov, A. V. Bykova, S. A. Stankevich, O. I. Aliev, A. V. Sidekhmenova, O. I. Dunaeva, V. A. Khazanov, A. I. Vengerovskii, V. V. Udut

“…GRS also alleviated endothelial dysfunction in animals with experimental PAH.…”
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Peripheral blood heat shock protein 27 correlates with information processing speed and executive function, potentially serving as a marker for mild cognitive impairment in patient... by Shufang Yang, Haoqiang Zhang, Wenwen Zhu, Tong Niu, Huzaifa Fareeduddin Mohammed Farooqui, Jue Wang, Mingyue Yang, Enlin Liu, Shaohua Wang

“…Abstract Background and aims Previous study found that interleukin 1β (IL-1β) is associated with diabetic cognitive dysfunction. Heat shock protein 27 (HSP27) is one of the factors related to IL-1β associated inflammation. …”
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Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure by Xiao Jin, Yi Ren, Li Wang, Hao Xie, Lu Huang, Juan Zhang, Zuo-Ying Hu

“…This study aims to investigate whether Pim3 is involved in DM-induced cardiac hypertrophy and HF and to elucidate its underlying mechanisms.Materials and Methods: DM was induced in mice by intraperitoneal injection of streptozotocin. …”
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The Impact of Acquired Hypothyroidism on the Growth and Metabolic Profiles of Pediatric Patients: A Retrospective Monocentric Study by Elena Malavolta, Ignazio Cammisa, Giulia Rotunno, Lucia Celeste Pane, Federica Arzilli, Giorgio Sodero, Donato Rigante, Clelia Cipolla

“…Additionally, we examined possible differences in lipid and glucose metabolism between the two groups. <b><i>Materials and Methods</i>:</b> We collected and analyzed data from the electronic medical records of 108 patients who were regularly followed up for thyroid dysfunction at the Pediatric Endocrinology Unit of the <i>Fondazione Policlinico Universitario A. …”
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Evaluation of Chlorogenic Acid in Parkinson’s Disease Model: An In-vitro Study in 6-OHDA Induced SH-SY5Y Cell Line by Sunprakathi Alwarsamy Perumalsamy, Kranthi Karunai Kadal, Gowri Viswanathan, Kavitha Ramasamy

“…Introduction: Parkinson’s Disease (PD) is the most common neurodegenerative movement disorder. Mitochondrial dysfunction is a key pathological driver of PD. Pharmacological agents used in PD are not disease-modifying therapies and do not influence mitochondrial activity. …”
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