Effect of tocilizumab on pulmonary gas exchange function in patients with severe COVID-19 by D. A. Lebedev, Yu. Kh. Dolya, G. E. Savkov, M. A. Godkov, E. V. Klychnikova, А. P. Shakotko, D. A. Kosolapov, S. N. Kuznetsov, A. M. Kvasnikov, Yu. N. Vrabiy, K. V. Kiselev, V. B. Poluektova, S. S. Petrikov, K. A. Popugaev

“…COVID-19 causes cytokine storm and acute respiratory distress syndrome, which can lead to severe lung damage and multiple organ dysfunction. Early use of monoclonal antibodies has shown promising results in cytokine storm therapy, but the effects on lung gas exchange function have not yet been studied.Aim. …”
Get full text

Results of qualitative test on fatty acid binding cardiac protein in suspected acute coronary syndrome and various kidney function level by V. A. Kokorin, E. A. Kochmareva, M. N. Arefiev, I. G. Gordeev

“…To evaluate diagnostic properties of qualitative tests for cardiac fraction of the fatty acid binding protein (cFABP) in patients hospitalized with suspected acute coronary syndrome (ACS), depending on glomerular filtration rate (GFR) level.Material and methods. Totally, 465 patients included, admitted with ACS within 24 hours from onset. …”
Get full text

Problems of using phenol (hydroxybenzene) and parabens as pharmaceutical stabilizers: analysis using machine learning methods by I. Yu. Torshin, O. A. Gromova

“…Despite their widespread use, the long-term toxicological effects of phenol and parabens remain largely unexplored.Objective: To conduct an analysis of the results of basic and clinical studies on chronic toxicity of phenol and parabens.Material and methods. The study included 544 articles found using the query “Preservatives, Pharmaceutical [MeSH Terms] AND Phenol [MeSH Terms]” in the PubMed/MEDLINE biomedical publications database. …”
Get full text

Galectin-3 as a Marker of Cardiorenal Syndrome in Patients with Chronic Heart Failure by V. I. Podzolkov, N. A. Dragomiretskaya, A. V. Kazadaeva, Yu. G. Belyaev, A. V. Tolmacheva

“…To assess the effect of renal dysfunction on the galectin-3 level in patients with chronic heart failure (HF) with preserved, intermediate and reduced left ventricular ejection fraction (EF).Material and methods. …”
Get full text

First experience of using two-dimensional speckle-tracking echocardiography to assess the association of left atrial strain with atrial fibrillation after coronary artery bypass... by K. G. Ganaev, E. E. Vlasova, A. A. Avalyan, M. A. Saidova, R. S. Akchurin

“…AF after CABG is probably associated with the existing subclinical LA dysfunction as a result of structural abnormalities due to coronary artery disease. …”
Get full text

ASSOCIATION OF THE METABOLIC SYNDROME CONSTITUENTS WITH MARKERS OF SUBCLINICAL TARGET ORGAN DAMAGE DURING FOLLOW-UP OF INTELLECTUAL LABORERS by O. P. Rotar, M. A. Boyarinova, E. V. Moguchaya, E. P. Kolesova, A. M. Erina, V. N. Solntsev, A. O. Konradi

“…In 2 years of observation there was markedly decreased number of patients with LVH and kidney dysfunction at the background of BP pattern improvement, and increase of the number of patients with thicker CIM, regardless of a decrease of the hypercholesterolemia patients. …”
Get full text

Prevention of Air Embolism in Extracorporeal Membrane Oxygenation Systems: An In Vitro Study on Protection of Central Venous Catheter Lumen by Danilo Franco, Nejc Krasna, Robert Novak, Giovanni Esposito, Raffaele Izzo, Jan Belohlavek, Marko Noc, Tomaz Goslar

“…The primary goal was to assess the impact of different air volumes on ECMO circuit performance at varying pump speeds. <i>Material and Methods:</i> The study utilized a circuit model to simulate ECMO conditions and evaluate the potential entry points of air, specifically through the unprotected lumen of the CVC. …”
Get full text

Peculiarities of cardiovascular remodeling in hypertensive patients at high additional risk with concomitant subclinical hypothyroidism by V. V. Syvolap, Ye. V. Novikov

“…Therefore, there is a need to study the influence of subclinical hypothyroidism on the cardiovascular remodeling peculiarities in patients with arterial hypertension (AH). Material and methods. The study involved 124 patients with AH stage II divided into two groups. …”
Get full text

Enhanced risk stratification scale for predicting death and non-fatal cardiovascular events in patients of the PROGNOZ IBS registry by S. N. Tolpygina, S. Yu. Martsevich, A. D. Deev

“…To develop a risk stratification scale for predicting cardiovascular events (CVEs) in patients with chronic coronary artery disease (CAD) based on the data from the PROGNOZ IBS registry.Material and methods. The PROGNOZ IBS registry included 641 patients (men, 500; women, 141) living in Moscow and the Moscow Region, who were routinely admitted to the National Medical Research Center for Therapy and Preventive Medicine from January 1, 2004 to December 31, 2007 with a preliminary diagnosis of CAD. …”
Get full text

Differentiating Maternal Angiogenesis Factors between Early and Late Onset Preeclampsia: Higher sflt-1 in Early Onset Preeclampsia, Lower PlGF and Higher sflt-1/PlGF Ratio in Late... by Joserizal Serudji, vaulinne Basyir, Tara Fadhillah

“…Background: Early onset preeclampsia (PE) is considered a fetal disorder that is associated with placental dysfunction. While late onset preeclampsia is considered a maternal disorder that associated with a normal placenta. …”
Get full text

Marker profile of myocardial remodeling in different etiopathogenetic forms of arterial hypertension in the experiment by Yu. M. Kolesnyk, M. I. Isachenko

“…The aim was to determine the morphodensitometric parameters of cardiomyocytes and features of the marker profile of remodeling in the left ventricular myocardium of rats with experimental hypertension of different etiopathogenetic forms. Materials and methods. The experiment was conducted on 20 male Wistar rats and 10 SHR which were divided into two groups of 10 animals each: the 1st –control; the 2nd – rats of the SHR line (EAH); the 3rd – 10 male Wistar rats with endocrine-salt arterial hypertension. …”
Get full text

Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description) by Avagimyan Ashot A., Mkrtchyan Lusine G.

“…However, acute cardiac dysfunction may also reflect the damage of myocytes, which may ultimately develop into early or late cardiotoxicity. …”
Get full text

Itopride hydrochloride efficacy in the management of delayed gastric emptying in type 1 diabetis mellitus patients in the presence of autonomic neuropathy by Irina Yur’evna Budennaya, Irina Vladimirovna Glinkina, Aleksey Vadimovich Zilov, Valeriy Mikhaylovich Makhov, Galina Afanas'evna Mel'nichenko

“…Materials and Methods. The total of 34 patients with T1DM, GMF dysfunction and DAN were selected for randomized, prospective, open-label, comparative study. …”
Get full text

Pathogenic and therapeutic roles of extracellular vesicles in sepsis by Benshuai You, Yang Yang, Jing Wei, Chenglin Zhou, Surong Dong

“…Sepsis is a systemic injury resulting in vascular dysfunction, which can lead to multiple organ dysfunction, even shock and death. …”
Get full text

The level of vasoactive intestinal polypeptide in patients with hypothyroidism and impaired intestinal function, and its association with markers of visceral hypersensitivity by V.H. Mishchuk, H.V. Kozinchuk, O.Z. Venhrovych, U.P. Shalamai, T.I. Salyzhyn

“…The mechanisms linking thyroid dysfunction with intestinal symptoms remain complex and incompletely understood. …”
Get full text

Correlation of Arterial Stiffness with Left Ventricular Global Longitudinal Strain and Diastolic Function in Hypertensive Patients by Ethar Saad Abbas, Oday J. Al-Salihi, Abdulhadi Hameed Alkaaby

“…Objectives: To detect subclinical involvement of left ventricular (LV) systolic and diastolic dysfunction in hypertensive patients in whom arterial stiffness is high. …”
Get full text

Documenting Visual Outcome of Descemet’s Stripping Endothelial Keratoplasty in A Tertiary Care Setting From Gujarat by Ami Tank, Falguni Mehta, Deepika Singhal, Anand Shah, Shivani Acharya

“…Objective:- To document Visual Outcomes Post Descemet Stripping Endothelial Keratoplasty (DSEK) amongst patients with endothelial dysfunction. Materials and Methods:- DSEK as a part of treatment was performed on 50 eyes of 50 subjects with endothelial pathology at a tertiary eye care institute in Gujarat. …”
Get full text

COMBINING OF DENTAL DEFECTS WITH DENTITION DEFORMATION AND DISEASES OF THE TEMPOROMANDIBULAR JOINT by I.A. Dmytrenko

“…Depending on the type of dentition defect, should be mentioned that the highest percentage of patients with a combination of TMJ dysfunction syndrome was discovered at presence unilateral distal unlimited defects of dentition - in 66.2% of patients with limited distal defects was discovered the syndrome of pain dysfunction in 64.3% of patients and in 62.2% of patients - with bilateral distal unlimited defects. …”
Get full text

Correlation of Impression Cytology and Tear Film Status with The Metabolic Control and Duration of Type 2 Diabetes Mellitus by Sharanyaa Krishnamoorthy, Rajalakshmi Selvaraj, Vanaja Vaithianathan

“…Materials and Methods: A cross sectional clinical study which includes 200 patients of type 2 Diabetes mellitus. …”
Get full text

Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Aim of the study: to reduce cognitive impairment during laparoscopic cholecystectomy by perioperative administration of drugs with antihypoxic and antioxidant effects under the control of stabilography.   Materials and methods. We studied the effect of general anesthesia and antioxidants on cognitive, static and locomotor functions during laparoscopic cholecystectomy. …”
Get full text