Heart rate-lowering therapy in gout patients with stable coronary artery disease: focus on ivabradine by N. N. Kushnarenko, T. A. Medvedeva, M. Yu. Mishko, T. M. Karavaeva

“…To study the effect of ivabradine and bisoprolol on cardiac hemodynamics and diastolic remodeling in gout patients with coronary artery disease and hypertension and without left ventricular systolic dysfunction.Material and methods. The open randomized parallel clinical trial of 35 men with intercritical gout at the age of 41,4±3,3 years, with class II-III stable angina, hypertension and sinus rhythm without data suggestive of heart failure was performed. …”
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Mildronate effectiveness in post-hospital rehabilitation of patients with myocardial infarction by V. P. Mikhin, O. N. Koltsova

“…Two types of diastolic dysfunction (DD) were defined: Type I (E/A <1; DTE >0,220 ms) and Type II (E/A >1,5; DTE <0,150 ms). …”
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Associations of circulating biomarkers with the presence and severity of coronary, carotid and femoral arterial atherosclerosis by V. A. Metelskaya, M. V. Zhatkina, N. E. Gavrilova, E. B. Yarovaya, N. L. Bogdanova, V. A. Kutsenko, B. A. Rudenko, O. M. Drapkina

“…According to the data obtained, the determinants of coronary and CA atherosclerosis are endothelial dysfunction (concentration of nitric oxide metabolites <36,0 μmol/L) and an increased level of creatinine (≥73,0 μmol/L). …”
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The Effects of Botulinum Toxin A Injections on Patients with Radiogenic Lower Urinary Tract Symptoms by Anke K. Jaekel, Ann-Christin Brüggemann, John Bitter, Franziska Knappe, Ruth Kirschner-Hermanns, Stephanie C. Knüpfer

“…Botulinum toxin A (BTX-A) injection into the detrusor vesicae is an established therapy for neurogenic lower urinary tract dysfunction as well as idiopathic overactive bladder. …”
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Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes by A. A. Khorlampenko, V. N. Karetnikova, A. M. Kochergina, Yu. S. Ignatova, E. V. Belik, O. V. Gruzdeva, N. K. Brel, A. N. Kokov, O. L. Barbarash

“…The obtained correlations between VAI and clinical and metabolic parameters confirm the practicability of using it to determine adipose tissue dysfunction in patients with/without CMD. The effect of increased VAI on the cardiovascular risk in high-risk patients requires further study.…”
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Comparative effectiveness of spirapril and enalapril in patients with coronary heart disease-caused chronic heart failure by S, Yu. Volkova, V. V. Ragozina, V. A. Balina, M. A. Pushnikova, V. A. Shchupletsova, S. V. Shalaev

“…During prospective 6-month follow-up, to compare spirapril and enalapril effectiveness in patients with coronary heart disease (CHD)-caused chronic heart failure (CHF). Material and methods. In total, 61 patients with CHD-caused CHF, according to inclusion/exclusion criteria, were divided into spirapril group (n=29; mean dose 5±1.3 mg/d) and enalapril group (n=32, mean dose 18.3±9.0 mg/ d). …”
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ROLE OF PULMONARY HYPERTENSION IN THE DEVELOPMENT OF CIRRHOTIC CARDIOMYOPATHY by M. V. Chistyakova, A. V. Govorin, E. V. Radaeva

“…To investigate the presence of pulmonary hypertension (PH) in patients with viral liver cirrhosis (LC) and its impact on some indicators of portal hemodynamics, and echocardiographic parameters.Material and methods. The study included 95 patients with viral LC. …”
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Kidney functional changes over time in liver recipients by E. D. Kosmacheva, A. E. Babich

“…Monitoring the glomerular filtration rate and preventing the progression of renal dysfunction in liver recipients…”
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Psychosomatic correlations in mentally ill and mentally healthy women with infertility by A. O. Nikolaevskaya, N. A. Tyuvina, V. D. Morozova, E. P. Kesler

“…In women with mental disorders, menstrual dysfunction together with psychopathological symptoms of illness (decrease in libido, communication, emotional numbness), decrease in social and family adaptation leads to impairment of reproductive function.…”
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MICROCIRCULATORY RESERVES AND TISSUE METABOLISM REACTIVITY IN VARIOUS STAGE ISCHEMIC CONGESTIVE HEART FAILURE by A. S. Klinkova, O. V. Kamenskaya

“…To assess microcirculatory reserves and tissue metabolism reactivity in patients with coronary heart disease (CHD) with various stages of chronic heart failure (CHF).Material and methods. Totally, 112 CHD patients included. …”
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Clinical efficacy of a fixed-dose combination of amlodipine/indapamide/perindopril in patients with hypertension and multiple risk factors by A. A. Pirozhenko, A. S. Ryabtsev, S. V. Shlyk, N. V. Drobotya, V. V. Kaltykova

“…To evaluate the antihypertensive and organ protective efficacy of the triple fixed-dose combination of amlodipine/indapamide/perindopril in patients with hypertension (HTN) who did not achieve target blood pressure (BP) on previous antihypertensive therapy (AHT).Material and methods. The study included 47 patients with HTN and multiple risk factors who did not achieve target blood pressure during previous AHT. …”
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Clinical effectiveness of eprosartan and hydroxyzine in patients with mild to moderate arterial hypertension and coexisting anxiety by G. V. Pogosova, E. E. Koltunov, E. Yu. Spivak, Yu. S. Belova, A. V. Karpova

“…No significant changes in cognitive dysfunction severity, according to Munsterberg test results, were observed. …”
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Measurement properties of sexual function assessment questionnaires in women with endometriosis: A systematic review following COSMIN guidelines by Anne Oppenheimer, Florence Boitrelle, Alba Nicolas‐Boluda, Arnaud Fauconnier

“…Different properties of PROMs used for sexual dysfunction were assessed according to the COnsensus‐based Standards for the selection of health Measurement Instruments (COSMIN) recommendations. …”
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ACTIVITY OF NITRO-OXIDATIVE PROCESSES IN PREGNANT WOMEN WITH IDIOPATHIC ARTERIAL HYPOTENSION by Leonid Markin, Olena Popovych, Alla Popovych

“…Significant increase in peroxynitrite is one of the causes of endothelial dysfunction. In pregnant women with IAH due to the low content of H2S - its vasoconstrictive effects are prevalent, which may indicate an indirect interaction between both of these systems of vasoregulation.…”
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Exploring the association between sleep quality, internet addiction, and related factors among adolescents in Dakshinkali Municipality, Nepal. by Sophiya Acharya, Anisha Chalise, Nirmal Raj Marasine, Shishir Paudel

“…This study aimed to explore the prevalence and contributing factors of poor sleep quality and internet addiction along with the relationship between sleep quality-related attributes and internet addiction.<h4>Material and methods</h4>A cross-sectional study was conducted among 243 adolescents of Dakshinkali Municipality, Nepal. …”
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Changes in Post-COVID Syndrome Manifestations and Bulbar Conjunctival Angioscopy Results in a Patient Undergoing Treatment after Mild COVID-19 by V. V. Arkhipov, T. S. Kheilo, E. G. Gladysheva, Yu. A. Danilogorskaya, M. R. Dzhavatkhanova, S. V. Snytko, I. V. Samorukova, M. V. Zhuravleva

“…Microcirculation dysfunction plays a significant role in the development of post-COVID syndrome caused by SARS-CoV-2. …”
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Features of eyelid microcirculation in chronic mixed blepharitis and type 2 diabetes mellitus by T. N. Safonova, G. V. Zaitseva, N. P. Kintyukhina, E. I. Timoshenkova

“…The presence of microcirculatory disorders is established in eyelids in chronic blepharitis and meibomian gland dysfunction. The article presents the results of the study concerning the peculiarities of neoangiogenesis as a mechanism of development of chronic blepharitis and meibomian gland dysfunction in diabetes mellitus (DM).AIM: to reveal the peculiarities of microcirculatory disorders of the eyelid in chronic mixed blepharitis in patients with type 2 diabetes mellitus (T2DM).MATERIALS AND METHODS: The study was conducted in 57 patients: 37 patients with chronic mixed bilateral blepharitis and a verified diagnosis of T2DM (group 1, n=74 eyes, average age 69.5 ± 7.5 years; subgroup 1a, n=38 eyes — patients with T2DM and glycated hemoglobin average level (HbA1с) 6.7±1.2; subgroup 1b, n=36 eyes — patients with T2DM and HbA1с average level 8.2±1.3) and 20 patients with chronic mixed bilateral blepharitis without signs of DM (group 2, n=40 eyes, mean age 67.2±4.3 years). …”
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Autonomic nervous system in pregnant women under martial law: the impact of forced relocation and stress on the functioning of autonomous regulation by M.Y. Malachynska

“…Autonomic nervous system (ANS) dysfunction is an important factor determining the course of pregnancy and maternal health. …”
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Myocardial Perfusion Imaging with Cardiovascular Magnetic Resonance in Nonischemic Cardiomyopathies: An In-Depth Review of Techniques and Clinical Applications by Ilir Sharka, Giorgia Panichella, Chrysanthos Grigoratos, Matilda Muca, Carmelo De Gori, Petra Keilberg, Giovanni Novani, Valerio Barra, Hana Hlavata, Matteo Bianchi, Denisa Simona Zai, Francesca Frijia, Alberto Clemente, Giancarlo Todiere, Andrea Barison

“…The aim of this review is to provide an up-to-date overview of CMR techniques for studying myocardial perfusion and their applications to nonischemic cardiomyopathy, not only to rule out an underlying ischemic aetiology but also to investigate the pathophysiological characteristics of microcirculatory dysfunction in these patients. <i>Materials and Methods</i>: We performed a structured review of the literature focusing on first-pass gadolinium perfusion sequences, stress protocols, and emerging pixel-wise perfusion mapping approaches. …”
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A COMPARATIVE ANALYSIS OF BIOEQUIVALENCE, CLINICAL EFFICACY AND SAFETY OF GENERIC VERSUS ORIGINAL CYCLOSPORINE AFTER KIDNEY TRANSPLANTATION by E. S. Stolyarevich, S. V. Badaeva, N. A. Tomilina, I. G. Kim, L. Y. Artyukhina, N. D. Fedorova, I. A. Bukharina

“…The aim of the study was the evaluation of pharmacokinetic parameters and clinical efficacy of generic cyclosporine (Ecoral) and Sandimmune Neoral. Materials and methods’. The pharmacokinetic parameters of different cyclosporine formulations. …”
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