Mechanisms of alleviating sepsis-induced rat lung and kidney damage by inhibiting expression of miRNA-939 by Anwaier Apizi, Jian Li, Yan Li, Zhaoxia Yu, Ruifeng Chai

“…These findings highlight the therapeutic potential of targeting miRNA-939 in the management of sepsis-induced organ dysfunction.…”
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Clinical features and mutational frequency of renal cell carcinoma from patients undergoing kidney transplant evaluation by Corbin J. Eule, Junxiao Hu, Kurtis D. Davies, Alkesh Jani, Alkesh Jani, Thomas Pshak, Elaine T. Lam

“…Despite increased understanding of genomic alterations in clear cell and papillary RCC, the most common subtypes, little is known about the effects of renal dysfunction on RCC pathogenesis.Materials and methodsThis retrospective study analyzed electronic medical records and pathology data from adult patients with renal cell carcinoma (RCC) who were evaluated for or received a kidney transplant at a single institution between 1995 and 2021. …”
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Renal transplant pathology and factors determining the rate of its progression by Е. S. Stoliarevich, E. T. Egorova, N. P. Mozheiko, D. A. Saydulaev

“…Objective: to evaluate the factors influencing the rate of nephropathy progression depending on the nature of dysfunction. Materials and methods. The study included 189 kidney transplant recipients with morphologically verified renal graft dysfunction. …”
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Heart transplantation in patients undergoing extracorporeal cardiopulmonary resuscitation in in‑hospital cardiac arrest by V. N. Poptsov, E. A. Spirina, A. K. Solodovnikova, A. S. Epremyan, A. A. Kuznetsova, A. S. Ignatkina, G. B. Glinkin, S. A. Budagaev

“…Five (19.2%) recipients developed severe dysfunction, which required continuation of peripheral VA-ECMO in the postperfusion period. …”
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Pulmonary Vascular Thrombosis in COVID-19: Clinical and Morphological Parallels by O. Ya. Porembskaya, V. N. Kravchuk, M. I. Galchenko, R. V. Deev, M. Sh. Chesnokov, A. V. Avanesyan, K. V. Lobastov, S. N. Tsaplin, L. A. Laberko, V. S. Ermakov, O. V. Pashovkina, I. V. Schastlivtsev, S. A. Sayganov

“…The D-dimer level correlates with lung, renal dysfunction, patients' mortality and doesn't show any correlation with ACT and can be accepted as a criterion of lung vessel thrombotic progression.…”
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Efficacy and safety of prolonged-release hyaluronic acid derivative vaginal application in the postpartum period: a prospective randomised clinical trial by Claudio Gustavino, Paolo Sala, Nadia Cusini, Brunella Gravina, Cecilia Ronzini, Diletta Marcolin, Valerio Gaetano Vellone, Michele Paudice, Rossella Nappi, Sergio Costantini, Simone Ferrero, Fabio Barra

“…Introduction In puerperium, the hypoestrogenic state induced by delivery and subsequently sustained by lactation may lead to vaginal dryness, burning, and itching sensation, contributing to the onset of sexual dysfunction.Material and methods This was a prospective, randomized, controlled, open-label study (NCT04560283) for evaluating the effects of application of a prolonged-release hyaluronic acid derivative vaginal gel in restoring sexual function during the postpartum period. …”
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Preemptive Analgesia with Nonsteroidal Anti-Inflammatory Drugs in the Perioperative Period by M. S. Danilov, I. S. Simutis, D. S. Salygina, E. G. Polovtsev, A. A. Syrovatsky, V. A. Ratnikov, A. A. Bogatikov, A. E. Karelov

“…More rare occurrence of renal dysfunction in Group 1 patients is indicative of lower nephrotoxicity of ibuprofen.…”
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Impact on the Quality of Erections after Completing a Low-Intensity Extracorporeal Shock Wave Treatment Cycle on a Group of 710 Patients by Héctor A. Corredor Ayala, José Pablo Saffon Cuartas, Diana Cerquera Cleves

“…The aim of this study is to evaluate the response to low-intensity extracorporeal shock wave therapy in a group of patients with organic vascular erectile dysfunction. Materials and Methods. This is an observational retrospective study. …”
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The Triglyceride–Glucose Index, a Marker of Insulin Resistance, Is Associated with the Myocardial Performance Index in Asymptomatic Subjects by Necip Nas, Muzaffer Aslan, Semih Saglik, Hafize Uzun

“…The MPI provides a comprehensive view of the overall efficiency of the heart’s pumping ability, making it a valuable tool for detecting early signs of heart dysfunction, even in the absence of overt symptoms. …”
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STRUCTURAL AND FUNCTIONAL FEATURES OF LEFT VENTRICLE IN PATIENTS WITH HEART FAILURE, CORONARY HEART DISEASE AND THYROTOXICOSIS by E. V. PASHCHENKO, A. I. CHESNIKOVA, V. P. TERENTYEV, V. I. KUDINOV, E. A. DEVETYAROVA

“…This study was designed to determine the structural and functional features of left ventricle in patients with heart failure, coronary heart disease and thyrotoxicosis.Materials and methods. 85 patients aged 58.3±5.6 years were divided into 3 groups: the main one – 25 patients with coronary  heart disease (CHD), chronic heart failure (CHF) II-III functional  classes (FC) and thyrotoxicosis, average age –59.23±3.81; the 1st  comparison group – 30 patients with CHD and CHF FC II-III without  thyroid dysfunction, the average age – 57.6±2.73; the 2nd  comparison group – 30 patients with thyrotoxicosis without  concomitant cardiovascular diseases (CVD), the average age –  45.4±3.51. …”
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Translation and validation of the brief version of the questionnaire of olfactory disorders-negative statements to Portuguese by Francisco Teixeira-Marques, Clara Pedro Mota, Adriana Cunha, Teresa Bernardo, Cristiana Coimbra, Conceição Fernandes, Roberto Estêvão, Paulo Moreira Gonçalves, João Pimentel, João Subtil, Nuno Lousan

“… Purpose: Olfactory dysfunction can lead to anxiety and depressive symptoms. …”
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Characterization of the gut microbiota and systemic inflammation in HIV-exposed uninfected infants from a resource-limited setting at 6 weeks of age by P. Munjoma, A. Mazhandu, J. Wyss, S. Ulrich Jordi, L. Katsidzira, B. Yilmaz, B. Misselwitz, K. Duri

“…Notably, several significant positive correlations were observed between inflammatory and endothelial dysfunction biomarker levels (p<0.05). However, no significant associations were found between gut microbial taxa relative abundances and plasma inflammatory or endothelial dysfunction biomarker levels. …”
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Clinical Outcomes in Diabetic Females Presenting with STEMI: A Cohort Study by Anjana Ajith Beena, Priya Shanmukhan, Veena Felix, Alummoottil George Koshy, Kunjukrishnapilla Sivaprasad

“…Conclusion: Despite a high rate of revascularisation and fewer procedure-related complications, outcomes remain grim, with a higher incidence of heart failure, cardiogenic shock, renal dysfunction and mortality. A worse clinical profile, left ventricular dysfunction and renal dysfunction were significant predictors of mortality.…”
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LONG-TERM AND LATE EFFECTS OF CHEMOTHERAPY IN CHILDHOOD ACLEUKEMIA AND THEIR MANAGEMENT SINGLE INSTITUTION OBSERVATIONUTE LYMPHOBLASTIC by Konul Baghirova

“…These adverse effects include cardiotoxicity, secondary malignancies, endocrine dysfunction, and neurological damage. Given the limitations of conventional treatment protocols, exploring less toxic and more effective therapeutic strategies is of critical importance. …”
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Fournier’s gangrene: the current state of the problem and our treatment experience by S. A. Aliev, E. S. Aliev

“…The OBJECTIVE of the study was to analyze the results of treatment of patients with lightning scrotal gangrene (Fournier’s gangrene).METHODS AND MATERIAL. The work is based on the analysis of the results of treatment of 31 patients with Fournier’s gangrene aged 32 to 82 years. …”
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Non-immunogenic staphylokinase in the high-risk pulmonary embolism treatment with subdural hematoma by S. L. Konstantinov, Zh. Yu. Chefranova, G. I. Stryabkova, S. A. Pribylov, I. B. Kovalenko, E. V. Gavrilyuk, S. V. Ivanov, S. S. Markin

“…To evaluate the safety and efficacy of the non-immunogenic staphylokinase in a patient with a massive high-risk pulmonary embolism (PE) with subdural hematoma.Material and methods. Non-immunogenic staphylokinase (Fortelyzin®, LLC “SuperGene”, Russia) is an original thrombolytic drug with high fibrin selectivity and minimal risk of bleeding. …”
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Diagnostic capabilities of instrumental methods for studying early cardiovascular adverse events in patients with lymphoproliferative disorders, quality and safety issues by G. R. Gimatdinova, O. E. Danilova, I. L. Davydkin, U. L. Dzhulakyan, E. V. Usenko

“…To study the possibilities of instrumental research methods in relation to the earliest detection of cardiovascular events in oncohematological patients receiving antitumor immunochemotherapy, as well as to deter­mine the requirements for documenting adverse events.Material and methods. For the study, 63 patients were prospectively selected with a diagnosis of indolent non-Hodgkin lymphoma, who were indicated for antitumor immunochemotherapy. …”
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Risk factors for myocardial infarction during carotid endarterectomy in high-risk patients with coronary artery disease by A. N. Vachev, O. V. Tereshina, O. V. Dmitriev, Yu. S. Belkin, P. A. Lebedev

“…In high-risk patients with CAD, severe impairment of local LV contractility and global LV systolic dysfunction are the most significant risk factors for perioperative MI during CEA.…”
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Synthesis, Characterization, and Antioxidant Activity of a New Copper(II)-imidazole Derivative Complex by Ariel Colaço de Oliveira, Ana Claudia Pedrozo da Silva, Antônio Gustavo Sampaio de Oliveira FIlho, Lilian Tatiani Dusman Tonin, André Luiz Tessaro, Felipe Nicolussi Pereira, Jonas de Arruda Leite Júnior, Rafael Block Samulewski

“…Degenerative diseases such as cancer, cataract, and cerebral dysfunction are increasingly associated with free radicals. …”
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Heart failure in cancer patients by A. F. Khalirakhmanov, A. Z. Sharafeev, G. D. Gatiyatullina, S. V. Zinchenko, R. F. Gaifullina, A. A. Rizvanov

“…The purpose of the study was to conduct a systematic review of data on the role of heart failure (HF) in the development of cancer, as well as to discuss problems dealing with diagnosis and treatment of heart failure in cancer patients. Material and methods. A literature search was conducted using the Cochrane library, elibrary, medline, and embase databases over the past 7 years. …”
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