SPECIAL ASPECTS OF IMPLANTATION OF A HEART PUMP SUPPORT SYSTEM AVK-N AS A «BRIDGE» TO HEART TRANSPLANTATION by T. A. Khalilulin, V. M. Zacharevich, V. N. Poptsov, G. P. Itkin, A. O. Shevchenko, R. Sh. Saitgareev, A. M. Goltz, A. R. Zakiryanov, N. N. Koloskova, N. N. Abramova, N. Y. Zacharevich, E. A. Nikitina, M. A. Danilina, S. V. Gautier

“…Aim: to develop an optimal surgical tactic for implantation of “AVK-N” system as a “bridge” to heart transplantation.Materials and methods. 17 patients were included. They were operated in the period from 2012 to October 2017 in Federal State Budgetary Institution «V.I. …”
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Meningococcal infection in children in the period 2012–2021. Main results of a retrospective multicenter study, issues of the day by A. A. Vilnits, Yu. V. Lobzin, N. V. Skripchenko, L. N. Mazankova, O. I. Klimova, A. Yu. Rtishchev, I. M. Osmanov, K. V. Markova, N. H. Tkhakushinova, G. P. Martinova, A. U. Sabitov, R. K. Babik, I. Ya. Izvekova, V. V. Krasnov, E. V. Sidorenkova, O. V. Borisova, N. M. Bochkareva, O. V. Samodova, V. V. Sokolovskaya, A. A. Girina, A. Yu. Kurganskaya, E. M. Simovanyan, M. A. Kim, O. A. Rychkova, L. V. Khanipova, S. G. Grigorev

“…At the time of discharge from the hospital, 30% of children had complications associated with meningococcal infection: organ dysfunction/ failure in 13.2% of patients (severe in 1.3%), cerebral insufficiency in 19.6%; severe psycho-neurological deficits, sensorineural hearing loss, problems associated with the need for orthopedic/surgical interventions accounted for 0.7%, 0.6% and 0.8%, respectively.Conclusion. …”
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Efficacy and Safety of First-Line Nivolumab Plus Ipilimumab in Patients with Postoperative Recurrent and Inoperable Non-Small Cell Lung Cancer: A Real-World Retrospective Observati... by Yuhei Kurata, Atsuto Mouri, Hisao Imai, Satoshi Endo, Kasumi Tsukamoto, Kenji Masaki, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Junichi Nakagawa, Kyoichi Kaira, Kunihiko Kobayashi, Hiroshi Kagamu

“…The incidence of grade ≥ 3 adverse events in the postoperative group included lung injury (13.3%), liver dysfunction (10.0%), adrenal insufficiency (6.7%), and colitis (6.7%). …”
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The Characteristic of Muscle Function for Sarcopenia in Patients with Rheumatoid Arthritis: A Large-Scale Real-World Cross-Sectional Study by Pei-Wen Jia, Jian-Zi Lin, Yao-Wei Zou, Zhi-Ming Ouyang, Ying Yang, Kui-Min Yang, Liu-Hong Liang, Jin-Yuan Han, Ze-Hong Yang, Jian-Da Ma, Lie Dai

“…It underscores the critical need for early identification and intervention of muscle dysfunction to improve their quality of life.…”
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First Russian experience in liver and kidney transplantation from donors with out-of-hospital cardiac arrest: 3 years’ results by O. N. Reznik, A. E. Skvortsov, V. S. Daineko, I. V. Loginov, A. A. Kutenkov, S. S. Komedev, V. M. Teplov, D. O. Kuzmin, A. N. Ananiev, I. V. Uliankina, D. V. Gogolev, A. A. Kukushkin, M. E. Malyshev, A. A. Boykov, V. E. Savello, A. N. Morozov, S. F. Bagnenko

“…In 1 (20%) case, there was severe liver allograft dysfunction for 33 days with subsequent complete restoration of function. …”
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Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial by Nick Daneman, Tony Mazzulli, Rob Stenstrom, Gail Klein, Ruxandra Pinto, Lisa Burry, Sheldon Cheskes, Jim Christenson, Damon C. Scales, Anna Rogowsky, Ian R. Drennan, Morgan Hillier, Sandra Jenneson, Philip Moran, Andrew M. Morris, Laurie J. Morrison, Gordon D. Rubenfeld, Christopher W. Seymour, P. Richard Verbeek

“…The final results will be disseminated to participating paramedic services through educational materials, presentations and interactive training. …”
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Upstream therapy of reperfusion disorders of hemodynamics, rhythm and conduction in patients with acute myocardial infarction with diabetes mellitus and metabolic syndrome (second... by M.I. Shved, I.O. Yastremska, R.M. Ovsiychuk, L.P. Martyniuk, O.A. Prokopovych, Ya.M. Kitsak

“…In patients with STEMI combined with T2DM and MS, hyperglycemia, insulin resistance and severe abnormalities of morphological and functional parameters of the heart with its systolic-diastolic dysfunction are observed at baseline, which are triggers of the complicated course of this pathology, with the deve­lopment of heart failure syndrome, rhythm and conduction disorders. …”
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The Clinical Presentation, Electrocardiogram and Echocardioscopy Features in Case of Acute Coronary Syndrome without ST Elevation Patients of Different Gender with Essential Arteri... by Shved M.

“…The Helicobacter pylori infection is one of the most common infections worldwide and there is an evidence about extra abdominal manifestation of this infection including coronary artery disease due to the systemic inflammation that leads to the endothelium damage with the consequent dysfunction and enhances coagulation and atherogenesis. …”
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Relationship between vitamin D and osteoarthritis by Natalia G. Kashevarova, Liudmila I. Alekseeva, Elena A. Taskina, Ekaterina A. Strebkova, Evgenia P. Sharapova, Natalya M. Savushkina, Kirill M. Mikhaylov, Svetlana I. Glukhova, Olga G. Alekseeva, Danil M. Kudinsky, Nikolay V. Demin, Elena Yu. Samarkina, Aleksander M. Lila

“…To evaluate the relationship of vitamin D levels with clinical and instrumental parameters in OA in a cross-sectional study. Materials and methods. The study included 171 patients aged 40–75 with confirmed knee OA according to the American College of Rheumatology (ACR) classification, stage I–III (according to Kellgren and Lawrence). …”
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Pirfenidone Prevents Myocarditis by Restoring Metabolic Hormone Levels in a Mouse MASH Model and its Effect on H9c2 Myoblast Viability under Glucolipotoxicity by Daniel López-Cifuentes, Ana S. Sandoval-Rodríguez, Ángel O. Vázquez-Esqueda, Jonathan S. Rodríguez-Sanabria, Juan Armendáriz-Borunda, Jorge Gutiérrez-Cuevas

“…Introduction and Objectives: Obesity, global epidemic, can cause metabolic dysfunction-associated steatohepatitis (MASH) and cardiovascular diseases. …”
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PERINATAL ASPECTS OF DELIVERY OF WOMEN WITH OBESITY AND GESTATIONAL DIABETES by О. Железняков, В. Лазуренко, І. Васильєва, Т. Фролова, Р. Сафонов, О. Лященко, О. Овчаренко

“…The aim of the study was to determine the characteristics of the delivery of women with obesity and gestational diabetes mellitus and to optimize the provision of obstetric care to them in order to reduce perinatal complications. Materials and methods of the study. Examination, antepartum preparation and delivery of 136 pregnant women were performed, including 33 (24.3%) obese women (group 1), 35 (25.7%) obese women and GDM (group 2), 38 (27.9%) with GDM (group 3) and 30 (22.1%) women with physiological pregnancy formed the 4th (control) group. …”
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FACTORS ASSOCIATED WITH HEARING IMPAIRMENT IN INFANTS WHO RECEIVED THERAPEUTIC HYPOTHERMIA by М. Соломенко, О. Харитонова

“…Principal risk factors for hearing dysfunction included severity of birth asphyxia, degree of postnatal clinical compromise, extent of cerebral tissue injury, and occurrence of postnatal infectious complications. …”
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Characteristics of the Respiratory System Status in Patients with Liver Cirrhosis and the Dependence of its Syntropic Lesions on the Severity of the Disease due to C. G. Child – R.... by Tolopko S. Ya.

“…Child – R. N. Pugh class. Materials and research methods. In a randomized way with preliminary stratification by the presence of respiratory dysfunction, caused by birth defects, hereditary diseases of respiratory system, infectious, autoimmune, allergic, neoplastic, toxic and occupational factors, identified as syntropic, we have involved into the study 93 cirrhotic patients (45.4 % of all surveyed persons [29 women (31.2 %) and 64 men (68.8 %) aged 27 to 73 years, the most able-bodied population category]) and divided them by the severity classes of LC (criteria of C. …”
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Correlation of Cardiovascular Risk Score with Alterations in Carotid Intima-Media Thickness in Patients with MASLD by José L. Vargas-Basurto, Ana D. Cano-Contreras, Héctor R. Ordaz-Alvarez, Genesis P. Martinez-Perez, Kevin D. Gonzalez-Gomez, Jose M. Remes-Troche

“…Introduction and Objectives: MASLD is associated with cardiovascular disease due to systemic inflammation and endothelial dysfunction. Carotid intima-media thickness (CIMT) and atherosclerosis are considered markers of generalized atherosclerosis and increased cardiovascular risk (CVR). …”
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Aspartate Aminotransferase to Alanine Aminotransferase Ratio and Arterial Stiffness in Persian Cohort Study by Sahar Sobhani, Sara Raji, Fatemeh Roudi, Mohamad Amin Bakhshali, Dina Javidjam, Effat Saghi, Zahra Ataee, Saeed Eslami Hasan Abadi

“…Introduction Liver function tests such as AST/ALT ratio may play an important role in the progression of nonalcoholic fatty liver disease (NAFLD) and its related cardiovascular dysfunctions. The study aims to assess whether AST/ALT was associated with arterial stiffness in a large population-based cohort of apparently healthy Persian women and men.Material and Methods: To evaluate arterial stiffness non-invasively, Pulse Wave Velocity (PWV) and Augmentation Index (AI) were measured in 5031 healthy adults. …”
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Epidemiological characteristics of brucellosis in the Omsk Region (2008-2019) by A. H. Nurpeysova, N. V. Rudakov, Yu. A. Pnevskiy, G. V. Berezkina, O. Yu. Starostina, S. Yu. Zelikman, V. V. Silaeva

“…Examination of contacts in dysfunctional foci of brucellosis revealed 8 cases of latent brucellosis. …”
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Polyvinyl alcohol improves resistance of epoxy-treated bovine pericardium to calcification in vitro by A. E. Kostyunin, M. A. Rezvova, T. V. Glushkova, D. K. Shishkova, A. G. Kutikhin, T. N. Akentieva, E. A. Ovcharenko

“…Around half of bioprosthetic heart valves become dysfunctional 15 years postimplantation because of structural valve deterioration notable for the degradation and calcification of the prosthetic tissue. …”
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Impact of chronic obstructive pulmonary diseases on static and dynamic balance by Hayam A. Hussien Abd Allah, Akram Abdelaziz Sayed, Alaa Rashad Mahmoud, Yasser Ramzy Lasheen, Saif Mehmed

“…Patients with chronic obstructive pulmonary disease exhibit dysfunctions in the peripheral muscular system as well as to the respiratory as well as circulatory systems. …”
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Hypertensive disease after moderate coronavirus infection. The results of six-month follow-up by D. О. Fedoseeva, I. M. Sokolov, Yu. G. Shvarts

“…This study aims to assess the clinical specificity of course of hypertensive disease (HD) during the first 6 months after new coronavirus infection (COVID-19) and to investigate prognostic significance of laboratory and instrumental parameters for organ dysfunctions in acute period of COVID-19 in patients with HD.Material and methods. …”
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Functional analyses of splice site variants in TCF12 by Angela Borst, Tilmann Schweitzer, Denise Horn, Erdmute Kunstmann, Eva-Maria König, Natalie Pluta, Eva Klopocki

“…Malfunctions during this process can lead to dysfunctional proteins and thus, to a variety of different human diseases. …”
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