The Predictive Value of Cystatin C for AKI in Patients with COVID-19 by M. O. Magomedaliev, D. I. Korabelnikov, S. E. Khoroshilov

“…AKI was diagnosed in 21 (17.9%) patients, kidney dysfunction without AKI was found in 22 (18.8%) patients with severe and extremely severe pneumonia associated with COVID-19. s-CysC and u-CysC levels in the group of patients with AKI were statistically significantly higher compared to the levels in the group of patients without AKI. …”
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Experience of using combined thermal and low-frequency stimulation in patients with lumbar sciatica by R. A. Bodrova, A. A. Ismagilova, A. R. Kamaleeva

“…To investigate the effectiveness of combined hardware thermal and low-frequency therapy in medical rehabilitation of patients with lumbar sciatica.   Materials and methods. A retrospective analysis of statistical data was carried out on 90 patients in the department of medical rehabilitation of patients with dysfunction of the peripheral nervous system and the musculoskeletal system of the treatment and rehabilitation center of the State Autonomous Healthcare Institution "City Clinical Hospital No. 7 named after M. …”
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The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier by Yu M, Jiang WJ, Yu M, Zhou Z, Wang M, Li L

“…However, the relationship between CDDP-induced inflammation and BLB dysfunction remains elusive.Materials and Methods: In vivo and in vitro BLB models were used to explore the inflammatory mechanisms underlying CDDP ototoxicity. …”
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Thyroid stimulating hormone (TSH) level variations in early pregnancy and feto-maternal outcome; retrospective study by N. Al-Husban, A. Hababeh, M. Al-Kasasbeh, R. Odeh, M. Shaheen, D. Moughrabi, D. Zabalawi

“…Conclusions: In singleton pregnancies of women without thyroid dysfunction and with negative anti-thyroid antibodies, variations of the TSH level in early pregnancy up to 4.0 mIU/L were not associated with a significant difference in most of the fetomaternal outcomes. …”
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P-69 EFFECTS OF POPULATIONAL-RELEVANT DOSES OF CARBOXYMETHYLCELLULOSE AND POLYSORBATE 80 EMULSIFIERS ON MASLD-ASSOCIATED HEPATOCARCINOGENESIS by GABRIEL BACIL PRATA, Julia Noveti Oliveira, Heloiza Ferreira Alves, Guilherme Romualdo Ribeiro, Luis Fernando Barbisan

“…Conflict of interest: No Introduction and Objectives: Hepatocellular carcinoma is the 3rd deadliest type of cancer worldwide and metabolic dysfunction-associated steatotic liver disease is the fast-growing cause of liver disease. …”
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The influence of a fentanyl and dexmedetomidine combination on external respiratory functions in acute hemorrhage model by Nikolay G. Vengerovich, Michael A. Yudin, Alexander S. Nikiforov, Georgiy S. Sagalov, Elina A. Ruzanova, Natalya V. Shperling, Alexander I. Vengerovskii, Igor A. Shperling, Alexander S. Makacheev

“…Four intramuscular injections of fentanyl 15 min, 30, 45 and 60 min after hemorrhage caused a severe respiratory dysfunction, accompanied by apnea periods and Biot’s respiration. …”
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Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse by G. B. Dikke, A. D. Makatsariya, A. M. Ziganshin, E. A. Shaikhieva, V. O. Bitsadze

“…Altering integrity of the specified muscle complex (rupture, in-labour overstretching) or its structural degradation characterized by loss of tone and contraction force, results in failed closing genital fissure, increased distance between the medial parts of m. levator ani in the lower third of the vagina and the loss of supporting and closing functions of the pelvic floor as well as POP development. Moreover, dysfunction of the constrictor muscles anatomically associated with neighbouring organs due to their common embryonic development, contributes to emergence of urinary and anal incontinence, despite the integrity of relevant sphincters.Conclusion. …”
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Risk factors for mild cognitive impairment in type 2 diabetes: a systematic review and meta-analysis by Yi Zhao, Hanlin Wang, Guanghao Tang, Leilei Wang, Xuewen Tian, Ran Li

“…This study synthesizes T2DM-MCI risk factors across clinical, lifestyle, and biochemical dimensions to support early identification and intervention of cognitive dysfunction in T2DM populations.Materials and MethodsThis systematic review and meta-analysis, following PRISMA guidelines, searched five databases for articles published from January 1, 2014, to December 31, 2024. …”
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Beneficial Role of Imeglimin as Add-on Drug with other Oral Hypoglycaemic Agents for Patients with Type 2 Diabetes: A Single centre Prospective Interventional Study by Naima Parveen, Sachin Chittawar

“…By addressing insulin resistance and β-cell dysfunction, imeglimin emerges as a dual-action therapy tailored for patients who are hesitant to initiate insulin. …”
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Spontaneous Fungal Peritonitis versus Fungiascites by Carlos F. Fajardo – Felix, Elda V. Rodríguez – Negrete, Patricia Manzano – Gallosso, Francisca Hernandez – Hernandez

“…Describe the characteristics of the patients with spontaneous fungal peritonitis or fungiascites. Materials and Patients: Three cases are presented. …”
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Saline nasal irrigation and gargling in COVID-19: Part II. Outcomes in Omicron and risk–benefit for self-care by S. Huijghebaert, C. Fabbris, C. Fabbris, A. L. Baxter, S. Parviz, U. S. Chatterjee, D. Rabago

“…If clean water and irrigation materials are provided, SNI can reasonably be recommended as early self-care for COVID-19, as it is for the common cold. …”
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A Comparative Study of Regional Cerebral Blood Flow Asymmetry Index in Stroke Patients with or without Poststroke Depression Using 99mTc-ECD Single-Photon Emission Computed Tomogra... by Pradeep Kumar Maurya, Abdul Qavi, Satyawati Deswal, Ajai Kumar Singh, Dinkar Kulshreshtha, Anup Kumar Thacker

“…This may reflect the dysfunction of the limbic system and contribute to the occurrence of PSD.…”
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Design, Synthesis, and Biological Evaluation of Novel Hydroxytyrosol Derivatives as Protectors for Vascular Endothelium Against Lipid Overload by Hou XX, Wang S, Ma XX, Wen Y, Li ZJ, Liu XY, Zhang X, Zhang Y, Qin XY

“…The aim of the study was to design and synthesize novel hybrid molecules to improve HT’s biological efficiency.Materials and Methods: A pharmacophore connection strategy was used to design and synthesize novel hybrid molecules by combining HT or its analogues with adamantane (ADM). …”
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HDL-C and BMI levels as parameters for MASLD detection by Stefanny Cornejo-Hernández, Esly Esquivel-Alarcón, Reyna Hernández-Espinoza, J. Salvador García-Hernández, Trinidad Baldovinos-Hernández, Javier Bastida-Alquicira, Eira Cerda-Reyes, Adriana Martinez-Cuazitl

“…Introduction and Objectives: Hepatic Steatosis Associated with Metabolic Dysfunction (MASLD) has a prevalence of 30% worldwide and 80% of these patients do not present alterations in liver biochemistry, therefore it is important to know if there is any biochemical parameter that helps us identify this population. …”
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Efficacy of Corticosteroid Therapy in Severe Community-acquired Pneumonia: A Monocentric Single-blinded Randomized Placebo-controlled Trial from a Tertiary Care Center in North Ind... by Anurag Dahra, Vidiyala Sai Sandeep, Kamal Singh, Pritam Singh, Mandeep Singla

“…Aim and background: A dysregulated immune response can produce acute lung injury and worsen clinical status of patient by causing organ dysfunction and severe pneumonia. Modulating the immune response can improve the outcome of illness and avoid treatment failures. …”
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HISTOGENETIC ASPECTS OF PNEUMOFIBROSIS DURING CONIOTIC CHANGES IN KUZBASS MINERS by Олег Иванович Бондарев, Сергей Николаевич Филимонов

“…The aim of the study was to identify trigger morphological mechanisms of the development of oncological pathology in miners with signs of pneumofibrosis, based on pathomorphological, immunohistochemical studies of changes in the tissue of the airways during epithelial-mesenchymal transformation, apoptotic activity, proliferation of smooth muscle cells (MMC) and endothelial dysfunction. Materials and methods. Histological, morphometric and immunohistochemical studies of pulmonary histione obtained during 60 autopsy operations of a group of Kuzbass miners. …”
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Laser technologies in surgery for benign prostate hyperplasia by S. A. Rakhimov, I.  V. Feofilov, I. A. Arbuzov

“…To compare the effectiveness and safety of laser technologies using the example of the use of diode and thulium lasers in BPH surgery.Materials & methods. The study included 89 men with BPH who underwent surgery from 2020 to 2022. …”
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Prognostic significance of the biomarker NT-proBNP in the surgical treatment of aortic stenosis (pilot study) by I. A. Kozlov, L. A. Krichevsky, V. Yu. Rybakov

“…The objective was to study the relationship between the preoperative blood levels of the N-terminal segment of B-type natriuretic peptide precursor (NT-proBNP) and ultrasound and thermodilution indicators of cardiac function before and after on-pump surgery for aortic stenosis, as well as to evaluate the prognostic significance of the biomarker in relation to postoperative myocardial dysfunction.Materials and methods. The study involved 27 patients aged 57.7±2.5 years who underwent aortic valve replacement. …”
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Structural and functional neural correlates of sensorimotor deficits in progression of hepatic encephalopathy by Guanchen Sha, Yuefan Liu, Yutong Cao, Qi Zhang, Yining Zhang, Yuanyuan Chen, Qiuyun Fan, Yue Cheng

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Enhancing personalised care in COPD exacerbation: the role of cardiac/inflammatory biomarkers by Pouria Khashayar, Kenneth Spearpoint, Patricia Khashayar, Manivannan Srinivasan, Thida Win

“…The relationship between COPD and cardiovascular diseases (CVD) is well established, with many studies confirming comorbidities, such as coronary artery disease, heart failure and diabetes mellitus, to significantly impact their prognosis.2,3 Thus, the role of cardiac dysfunction in increasing the mortality rate (between 30% and 60%) in COPD individuals is well documented and known to be closely linked to advancing age as well as long-term disabilities and, therefore, is a tremendous burden on society.4 Materials and Methods: A systematic literature review in PubMed and Web of Science using keywords including ‘Exacerbated COPD’, cardiovascular events such as ‘cardiovascular mortality’, ‘coronary heart disease’, ‘CVD’, ‘myocardial ischemia’ and ‘heart failure’ and cardiac/inflammatory biomarkers (‘Troponin’, ‘B-Type Natriuretic Peptide (BNP)’ and ‘C-Reactive Protein (CRP)’) was undertaken to help provide a better picture of this association. …”
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