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2401
Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells
Published 2016-04-01“…Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg) cells. Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. …”
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2402
Boosting Hydroxyl Radical Generation with Nitrogen Vacancy–Modified Carbon Nitride for Triggering Dual Damage of Cancer Nucleus DNA–Mitochondria against Hypoxic...
Published 2025-07-01“…Under illumination, NV-PCN generates a burst of •OH around the nuclei and mitochondria of Cal-27 cells, which effectively kills the cells via synchronously leading to DNA damage and mitochondrial dysfunction. Compared to the conventional photosensitizer chlorin e6, NV-PCN–based PDT exhibits excellent anticancer performance in vitro and in vivo, highlighting its potential as a next-generation therapeutic agent.Conclusion: Collectively, the high •OH-generation efficiency, strong anticancer activity, and overall safety of the O2-independent nanoparticle opens up new avenues for in-depth study on carbon nitride-based cancer PDT strategies. …”
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2403
The contribution of modifiable risk factors to the formation of cardiovascular remodelling and vegetative balance in patients with essential hypertension
Published 2017-12-01“…The addition of any single RF in patients with EH is associated with an increase in the size of left atrium, left ventricular myocardial mass index mainly due to thickening of the interventricular septum, diastolic dysfunction of the left ventricle. The addition of any RF in the examined patients is accompanied by a tendency to decrease in blood flow in all vessels basins, but mainly in the common carotid arteries. …”
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2404
Impact of cognition and psychoemotional status on falls in multiple sclerosis
Published 2020-12-01“…More than 50% of multiple sclerosis patients experience falls associated with accumulating disability, bladder dysfunction, and imbalance. However, impact of psychoemotional factors, including depression, anxiety, and cognition, on the risk of falling has not been studied in Lithuania so far. …”
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2405
Harnessing natural polymers and nanoparticles: Synergistic scaffold design for improved wound healing
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2406
Cardioprotective effects of the estrogen receptors modulators in the conditions of experimental acute myocardial infarction
Published 2017-12-01“…Aim of study – to evaluate the SERM cardioprotective effects in the conditions of acute myocardial infarction modelling with the use of the ST2 marker. Materials and methods: The experimental part of the work was performed on 120 mature rats - males weighing 190–230 grams. …”
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2407
Application of T1 MRI in takotsubo cardiomyopathy
Published 2025-07-01“…Introduction: Takotsubo cardiomyopathy is a temporary and severe left ventricular dysfunction caused by extreme emotional or physical stress, which confers significant mortality and morbidity.1 Cardiac magnetic resonance (CMR) sequences have been analysed to determine their diagnostic abilities in takotsubo patients. …”
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2408
Frequency of detection and factors of elevated levels of diabetes-associated autoantibodies in the blood of patients with clinical type 2 diabetes mellitus
Published 2025-04-01“…The purpose of the study: to assess the frequency of detecting elevated GADA autoantibodies in patients with a clinical course of T2DM and to determine their association with clinical, metabolic, and social characteristics. Materials and methods. The study included 48 participants with clinically diagnosed T2DM, 30 (62.5 %) men and 18 (37.5 %) women. …”
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2409
Relation between Uric Acid Levels, Creatinine and Body Mass Index in Hypertensive Women and Men
Published 2014-09-01“…Materials and methods. The study involved 74 patients with hypertension (37 females and 37 males) aged 30–78 years (mean age – 59.7 ± 1.7 years). …”
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2410
Ustilaginoidin D Induces Acute Toxicity and Hepatotoxicity in Mice
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2411
The influence of intermittent venovenous hemodiafiltration on the course of acute kidney injury in multiple trauma victims
Published 2024-11-01“…The purpose was to study the effect of intermittent venovenous hemodiafiltration (HDF) on indicators of renal function, hemodynamics, homeostasis and inflammation in multiple trauma victims with rhabdomyolysis and AKI. Materials and methods. Fifty victims with multiple trauma complicated by rhabdomyolysis and AKI were examined. …”
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2412
Anxiety and depression in patients with head and neck cancer: 6-month follow-up study
Published 2016-04-01“…The results showed that depression was predicted by sticky saliva (P<0.001) and trouble with social contact (P<0.001) at 3 months, and trouble with social eating (P<0.001) at 6 months.Conclusion: Patients with HNC experienced different changes in anxiety and depression in the first 6 months of treatment. Dysfunction in salivation, problems with eating, and problems with social contacts were major risk factors for depression.Keywords: depression, anxiety, quality of life…”
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2413
Salivary Biomarkers as a Predictive Factor in Anxiety, Depression, and Stress
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2414
Hemostasis in pregnant, parturient and puerperal women with preeclampsia
Published 2020-10-01“…As a result, vascular microthrombosis in diverse organs with developing endothelial dysfunction, impaired utero-placental blood circulation emerge that leads to adverse perinatal outcomes.Aim: to study status of coagulation arm in pregnant women with moderate and severe PE, after delivery by cesarean section, to optimize management of the postoperative period.Materials and Methods. …”
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2415
Oxidative stress pattern of patients with abnormal thyroid function in Southern Nigeria
Published 2025-01-01“…A key finding from this study is that thyroid dysfunction may not cause oxidative stress through lipid peroxidation. …”
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2416
Low Serum Cholinesterase Levels Predict Poor Prognosis in Patients with Ovarian Cancer
Published 2025-02-01“…This study aimed to evaluate the clinical significance of serum ChE levels as a prognostic biomarker in ovarian cancer.Materials and Methods: A retrospective cohort analysis was conducted on 168 patients diagnosed with epithelial ovarian cancer at the Suzhou Ninth People’s Hospital from 2019 to 2020. …”
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2417
Prevalence of fibrosis and steatosis determined by transient elastography and controlled attenuation parameter (Fibroscan®) in diabetic patients
Published 2025-04-01“…Introduction and Objectives: Globally, a higher prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) has been reported in diabetics (55.5%) compared to the general population (25%). …”
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2418
Current State And Trends In The Incidence Of Chronic Kidney Disease Among Adult Population And Opportunities For Its Prevention And Treatment In Moscow Healthcare Organizations
Published 2024-11-01“…Showing no symptoms at early stages, chronic kidney disease (CKD) is closely related to diabetes mellitus, hypertension, obesity and kidney dysfunction in older age, which requires long-term and expensive treatment. …”
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2419
Septal alcohol ablation in patients with hypertrophic cardiomyopathy and left ventricular outflow tract obstruction
Published 2025-01-01“…BACKGROUND: Hypertrophic cardiomyopathy is a primarily genetically determined myocardial disease characterized by pronounced, often asymmetric, myocardial hypertrophy that results in diastolic dysfunction and left ventricular outflow tract obstruction. …”
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2420
Long-term Patient-reported Functional Outcome after Pelvic Ring Injuries: Analysis using Two Different Types of Outcome Scores
Published 2025-06-01“…We evaluated long-term (>1 year) functional outcome of these patients using patient-reported outcome measures) using both generic health-specific and disease-specific outcome instruments. Materials and Methods: Pelvic ring injury patients seen between 2015 and 2020 were called for a follow-up visit. …”
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