Practical experience and clinical results of reconstructive surgical correction of primary and secondary mitral regurgitation by V. V. Osaulenko, V. O. Hubka, K. O. Chmul, S. Yu. Nakonechnyi, R. I. Budahov

“…Mitral valve surgery is indicated in symptomatic patients with severe insufficiency and asymptomatic individuals with left ventricular systolic dysfunction, pulmonary hypertension, or atrial fibrillation. …”
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The Impact of Age and Pathogens Type on the Gut Microbiota in Infants with Diarrhea in Dalian, China by Qingjie Fan, Ming Yi, He Liu, Yushuang Wang, Xinke Li, Jieli Yuan, Lili Wang, Binbin Hou, Ming Li

“…Diarrhea in infants is a serious gastrointestinal dysfunction characterized by vomiting and watery bowel movements. …”
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Utilization of dexrazoxane in patients treated with doxorubicin: a retrospective, propensity matched analysis of cardiac function and toxicity by Zachary M. Neiman, Carlo S. Legasto, Alan K. Chin, Tiffany Guan, Brian C. Schulte, Brian C. Schulte

“…IntroductionDexrazoxane (DZR) has been used to prevent cardiotoxicity from doxorubicin (DOX), particularly in younger patients with cancer and those with pre-existing cardiac dysfunction. Herein, we sought to further define the role of DZR by evaluating its capacity to mitigate cardiotoxicity in patients actively receiving DOX, while also assessing concomitant toxicities.Materials and methodsWe conducted a retrospective, propensity-matched cohort study at a single academic center, comparing outcomes between patients treated with DZR plus DOX and those who received DOX alone. …”
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The Effectiveness of Acth Therapy According to Etiology in Patients with West Syndrome and Its Long-Term Effects on Bone Mineral Metabolism and Adrenal Pathway by Mesut Güngör, Mine Düzgöl, Hülya Maraş Genç, Emek Uyur Yalçın, Filiz Mine Çizmecioğlu Jones, Bülent Kara

“…It was demonstrated that there is no risk in terms of bone metabolism and adrenal dysfunction in the subacute-chronic period after ACTH treatment.…”
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A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Saïda, Algeria by Lamia Abir Tazi, Yasmina Benabdesslem, Sabrina Amara, Kadda Hachem

“…These disorders involve persistent digestive symptoms indicative of digestive tract dysfunction.Materials and Methods: A survey examining the utilisation of probiotics and medicinal plants as supplementary treatments was conducted on 160 patients with GI disorders at healthcare institutions in Saïda from March to April 2023 using questionnaires that had been previously adapted and tested for reliability with Cronbach’s alpha test. …”
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Comparative Pathomorphological Characteristics of Placental Vessels from Pregnancies with High and Low Risk of Preeclampsia by Kamilya Makhambetova, Yevgeniy Kamyshanskiy, Olga Ponamareva, Zhanna Amirbekova, Nazerke Oshakhtiyeva

“…The large variability and inconsistency of histomorphometric changes in placental vessels as markers of placental dysfunction emphasize the need for their further research using standardized methods of morphometric analysis. …”
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Non-immune diabetes mellitus in children due to heterozygous mutations in the glucokinase gene (GCK-MODY): data of 144 patients by E. A. Sechko, T. L. Kuraeva, L. I. Zilberman, D. N. Laptev, O. B. Bezlepkina, V. A. Peterkova

“…BACKGROUND: Monogenic diabetes mellitus (MDM) is a rare form of diabetes mellitus (DM) which caused by one or more mutations in one of the genes that cause pancreatic β-cell dysfunction. Despite the sufficient knowledge of the most common subtypes of MODY, cases of MDM are undiagnosed and classified as type 1 diabetes mellitus and type 2 diabetes mellitus.AIM: To study the clinical, laboratory characteristics, as well as age-related features of GCK-MODY in children.MATERIALS AND METHODS: The studied population is patients with GCK-MODY under the age of 18 years. …”
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Treatment of overactive bladder symptoms in women with Diunorm®: preliminary results report by S. V. Shkodkin, M. V. Pokrovsky, S. S. Krasnyak, A. V. Polichuk, S. V. Chirkov, O. V. Churikova, N. A. Kpavtsova

“…To assess the effectiveness and safety of the drug Diunorm® (in caps.) in the prevention and treatment of OAB in women.Materials and methods. The statistical analysis includes the results of a survey of 28 women with symptoms of OAB, whose average age was 35.3 years. …”
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Beclin-1 as a potential prognostic marker in correlation with E-cadherin in oral lichen planus and oral squamous cell carcinoma: an immunohistochemical analysis by Heba N. Shalash, Radwa R. Hussein, Fatma Seragel-Deen

“…Beclin-1 happens to be one of the proteins regulating autophagy, where its dysfunction has been involved in various disorders. …”
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The influence of the interaction of right ventricle and pulmonary artery system on the development of adverse outcomes in acute decompensation of chronic heart failure by Madina R. Islamova, Ayten F. Safarova, Zhanna D. Kobalava

“…To determine the frequency and prognostic significance of right ventricular-pulmonary artery (RV-PA) uncoupling, in the development of cardiovascular complications in patients with acute decompensation of chronic heart failure (ADCHF). Materials and methods. The prospective single-center observational study included 171 patients with ADCHF. …”
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Comparative Effectiveness of Myofascial Release and Instrument Assisted Soft-tissue Mobilisation in Improving Flexibility of the Hamstring Muscle: An Experimental Study by Haritima Wadhwa, Megha Nijhawan

“…This tightness is commonly linked with movement dysfunction in the lumbar spine, pelvis, and lower limbs, which can result in low back pain, gait abnormalities, and other issues. …”
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SURGICAL TREATMENT CHOICE FOR PATIENTS WITH NON-RESECTABLE PANCREATIC HEAD CANCER by Borys H. Bezrodnyi, Ihor V. Kolosovych, Yevhenii O. Nesteruk

“…With a Karnofsky index <80, it is advisable to perform stenting of the common bile duct with SEMS, with a Karnofsky index >80, double biliodigestive and prophylactic gastrodigestive bypass surgery should be performed. When multiorgan dysfunction and cholangitis develop against the obstructive jaundice, the treatment consists of two stages, the first – transpapillary biliary drainage with plastic stents, the second – elective surgical intervention.…”
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Assessment of association between the Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications by S. O. Ostafiichuk

“…Aim – to determine the association between Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications. Materials and methods. A total of 97 women with normal prepregnancy weight, singleton pregnancy, delivery at 37 weeks or more and without chronic diseases with follow-up of pregnancy and 1 year after delivery at antenatal clinics. …”
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Global longitudinal strain and its dynamics after replacement of aortal valve in patients with severe aortic stenosis by N.V. Ponych, O.O. Nemchyna, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…The aim – to determine factors that may influence the global longitudinal strain (GLS) and its dynamics after replacement aortic valve (RAV) in patients with severe aortic stenosis (AS). Materials and methods. In a one-center prospective study, 30 patients with severe AS were sequentially screened for RAV surgery. …”
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Mobile-phone-based e-diary derived patient reported outcomes: Association with clinical disease activity, psychological status and quality of life of patients with multiple scleros... by Daniel Golan, Smadar Sagiv, Lea Glass-Marmor, Ariel Miller

“…Secondary objectives were to evaluate the construct and predictive validity of e-diary derived PROs and to explore the various factors that were associated with changes in PROs over time.<h4>Materials and methods</h4>In this observational cohort study patients downloaded an MS tailored e-diary into their personal smartphones. …”
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Immunohistochemical study of the brain glutamine synthetase expression in the rat septic model by T. V. Shulyatnikova, V. O. Tumanskiy

“…Severe sepsis is accompanied by multiple organ dysfunction where acute liver failure (ALF) plays one of the most critical roles. …”
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Relationship of cardiac and carotid arteries remodeling in women with arterial hypertension by I. M. Zubko

“…Significant and reliable negative relationship between media thickening, inner diameter of carotid arteries index and left ventricle EF has been established; it may indicate new peculiarities of the initial impact of vascular remodeling onLV systolic dysfunction development.…”
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Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity by Abdulla A. Albishtue, Aqeel Mohsin Al-Mahmmodi, Hasan A. Almamoori, Mustafa Ali Alahmer

“…These findings suggest PRO as a promising candidate for mitigating heavy metal-induced reproductive dysfunction.…”
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One-stage buccal two-flap urethroplasty using the Kulkarni technique for extended anterior urethral strictures by M. I. Katibov, M. M. Alibekov, Z. M. Magomedov, A. M. Abdulkhalimov, V. G. Aydamirov

“…The use of this technique for recurrent forms of the urethral stricture (recurrence after the previous urethroplasty) is the most significant risk factor for treatment failure. 1 (5.6%) case of erectile dysfunction and stress urinary incontinence has taken place of the late postoperative complications.Conclusions. …”
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The diagnostic value of brain natriuretic peptide in men with comorbid essential arterial hypertension and type 2 diabetes mellitus by Ya. O. Antoniuk, A. F. Humeniuk, Yu. P. Pashkova, O. O. Sakovych, V. M. Zhebel

“…The aim of the work is to investigate the diagnostic informativeness of brain natriuretic peptide (BNP) in men with left ventricular (LV) diastolic dysfunction (DD) and initial stages of chronic heart failure (CHF) in comorbid stage 2 essential hypertension (EH 2) and type 2 diabetes mellitus (T2DM). …”
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