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Markers of endothelial damage in children with diabetic ketoacidosis
Published 2025-06-01“…DKA can lead to endothelial dysfunction (ED), but the diagnostic criteria for this condition have not been well studied in this urgent condition. …”
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2262
Pathogenesis of Cardiac Depression in Acute Destructive Pancreatitis
Published 2016-02-01“…Objective is to identify the pathogenic factors for progression of pancreatogenic cardiac failure in the nearest and remote periods.Materials and methods. The study was carried out on 130 male Wistar rats (292±4.0 g) divided into 4 groups. …”
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2263
The approaches to prevention and therapy of cardiovascular disorders in children with chronic bronchopulmonary pathology
Published 2018-06-01“…It has been established that there is a structural and functional left ventricular myocardium rearrangement on the background of left ventricular diastolic dysfunction development, sympathetic branch of the autonomic nervous system functional impairment, myocardium electrical instability and endothelium-depended vasodilation disturbance in children with chronic bronchopulmonary diseases. …”
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2264
Adverse events that occurred in patients with rheumatoid arthritis during long-term follow-up
Published 2023-10-01“…As the prospective long-term follow-up shows, despite the decrease in RA activity, the number of patients with ankylosis, joint dysfunction and concomitant diseases increased. In the structure of concomitant diseases coronary heart disease and arterial hypertension dominated. …”
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2265
What does not Kill You Makes You Stronger: An Online Survey into Healthcare Providers’ Mental Health during Corona Pandemic
Published 2022-03-01“…Conclusions: High unmet mental health needs of HCPs are evident in increased burden of sleep dysfunction, medical morbidity, and reluctance to disclose about psychological issues. …”
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2266
Laser confocal microscopy of corneal nerve fibers in patients with burning eye syndrome and dry eye disease
Published 2024-03-01“…The criterion for exclusion from the study was the presence of clinical signs of blepharitis and dysfunction of the meibomian glands in patients and individuals of the control group. …”
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2267
Characteristics of the Autonomic Nervous System State in Patients with Systemic Lupus Erythematosus with the Different Activity Degree According to the Indices of Heart Rate Variab...
Published 2015-03-01“…Regarding the pathogenesis of the autonomic nervous system (NS) dysfunction in the presence of systemic lupus erythematosus (SLE), there are several hypotheses: the occurrence of vasculitis with the involvement of vessels of the nerves, or secondary amyloidosis; the influence of immunological factors, in particular, circulating antibodies to the structures of the NS were detected. …”
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2268
Advances in research on biomaterials and stem cell/exosome-based strategies in the treatment of traumatic brain injury
Published 2025-07-01“…This review also examines the utilization of endogenous bioactive materials in the treatment of TBI.…”
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2269
The prognostic significance of BRCA1 gene expression in patients with breast cancer
Published 2019-07-01“…Of particular interest is the assessment of the deficit of homologous recombination, which may include various dysfunctions of the BRCA1 gene. Moreover, it has been shown that a decrease in the functional activity of BRCA1 is reflected in the sensitivity of the tumor to DNA damaging agents, and the prognosis of the disease becomes more favorable.Objective: assessment of the association of BRCA1 gene expression in a breast tumor with the prognosis of the disease.Materials and methods. …”
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2270
Pain Associated with Endometriosis. A Review of Quality of Life. Psychological Aspects, Career Development, Sexual Health, and Intimate Partner Relationships
Published 2025-02-01“…The main symptoms include severe pain, reduced fertility, and sexual dysfunction. Treatment includes pharmacotherapy and surgical interventions, depending on the severity of symptoms, the location of lesions, and their extent. …”
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2271
Sensory integration disorders - a problem for children in the modern world
Published 2024-04-01“…Abstract The aim of the article is to present the function and importance of sensory integration in everyday human functioning. Material and methods Analysis of the literature on the subject Results On the basis of scientific studies, a concise characterization of sensory integration processes and their dysfunctions was made. …”
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2272
In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease
Published 2025-05-01“…<b>Conclusions:</b> Our findings have profound implications for genetic disorder therapies, highlighting the potential of nano-engineered materials for silencing mutant genes and facilitating molecular transfection across cellular barriers. …”
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2273
Physical Activity vs. Pharmacotherapy in PCOS Treatment: A relief of Clinical Evidence on Exercise and Metformine Efficacy
Published 2025-08-01“… Introduction Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, characterized by hormonal imbalance, insulin resistance, and ovulatory dysfunction. It presents with a wide range of symptoms, including menstrual irregularities, hyperandrogenism, and metabolic disturbances, often leading to infertility and increased long-term cardiometabolic risk. …”
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Expert consensus on the management of pharmacodynamic breakthrough-hemolysis in treated paroxysmal nocturnal hemoglobinuria
Published 2024-12-01“…Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, non-malignant hematologic disease characterized by complement-mediated hemolysis (with or without hemoglobinuria), fatigue, increased susceptibility to thrombosis, and bone marrow dysfunction. The development of complement inhibitors has transformed outcomes for patients with PNH, but patients may still experience pharmacodynamic breakthrough hemolysis (BTH), which can be caused by exposure to a complement amplifying condition (CAC), such as vaccination, infection, or surgery.Materials and methods: A 13-member expert panel used a validated methodology (a RAND/UCLA modified Delphi panel) to develop consensus on how to classify pharmacodynamic BTH in patients with complement-inhibitor treated PNH. …”
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2276
To study the prevalence of metabolic-associated fatty liver disease in a tertiary hospital in Bundelkhand region
Published 2025-06-01“…Background: Metabolic-associated fatty liver disease (MAFLD) is a growing global health concern associated with metabolic dysfunction, including obesity, type 2 diabetes mellitus, and dyslipidemia. …”
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2277
<i>FABP4</i> gene expression in subcutaneous and visceral adipose tissue in patients with obesity and type 2 diabetes mellitus
Published 2022-07-01“…The expression level of FABP4 gene in AT can act as a marker of AT dysfunction in obesity.…”
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2278
To Increase the Practice of Hand Washing with the Correct 7-Step Technique for 2 Minutes for Doctors Conducting Vaginal Deliveries from Baseline to 80 % in 4 Weeks
Published 2022-10-01“…Local problem: In the labour room, it was found that doctors who are conducting deliveries are not doing hand washing with the correct steps for 2 minutes as often as they should. Materials and Methods: A quality improvement team was formed. …”
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2279
Radiofrequency Electromagnetic and Pulsed Magnetic Fields Protected the Kidney Against Lipopolysaccharide-Induced Acute Systemic Inflammation, Oxidative Stress, and Apoptosis by Re...
Published 2025-01-01“…<i>Materials and methods</i>: Forty female Wistar albino rats were randomly divided into five groups (each containing eight rats): control, LPS, RF-EMF, PMF, and RF-EMF + PMF groups. …”
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The ADVanced Organ Support (ADVOS) Hemodialysis System in Postoperative Cardiogenic Shock and Multiple Organ Failure: First Results in Cardiac Surgery Patients
Published 2025-06-01“…A multimodal approach at targeting organ dysfunction seems to be a promising strategy, encompassing both hemodynamic support as well as differentiated organ replacement therapy. …”
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