Research the therapeutic, physicochemical, and pharmaceutical properties of the active compounds found in Tribulus terrestris (TT) by Roohallah Yousefi, Ali Jamshidi

“…The physicochemical and pharmacological characteristics of Tribulus terrestris are currently being studied.Methods and Materials: We utilized the PubChem database to gather data on the studied compounds, including their formulas and structures. …”
Get full text

Pathogenic effects of plasma thiols in patients with psoriasis on background of arterial hypertension by G. I. Makurina

“…These changes characterize the progression of endothelial dysfunction in these patients. Conclusion. Formation of psoriasis progression was significantly associated with low functional capacity glutathione link of antioxidant system and with the inability to adequately replenish the pool of reduced glutathione. …”
Get full text

Evaluation of serum vascular cell adhesion marker-1 in β- thalassemia major patients by Nuha Abd Ali Al-Sarai, Subh Salim Al-Mudallal, Rana Rai’d Najm

“…OBJECTIVES: The aim of this study was to evaluate the level of soluble VCAM-1 in β-thalassemia major patients and to correlate its level with the clinical parameters. PATIENTS, MATERIALS AND METHODS: This case–control study was enrolled on 40 patients with β-thalassemia major. …”
Get full text

LEFT VENTRICLE FUNCTIONAL STATUS DYNAMICS THROUGH VARIOUS ISCHEMIA CLINICAL COURSES AFTER AN ENDURED ACUTE CORONARY SYNDROME by D. A. Shvets, S. V. Povetkin

“…As a result of the comparison of clinical instrumental parameters a global and a segmental LV dysfunctions were discovered among the patients with the aggravated IHD clinic course 24 months after an endured ACS.…”
Get full text

Assessing sexual function and vulvovaginal symptoms in young patients with vulvar dystrophy by A. G. Solopova, E. E. Achkasov, A. D. Makatsariya, I. V. Khamani, T. A. Blbulyan, V. S. Moskvichyova

“…Results. Severe sexual dysfunction (FSFI score 2) was detected in 14 % of cases (n = 8) in group 1 (sclerotic lichen vulva) and 17 % (n = 11) in group 2 (mixed dystrophy). …”
Get full text

Left Atrial Strain by 2D Speckle Tracking Echocardiography in Patients with Systemic Hypertension in Babylon Province by Ali Hamid Abbas Al-Murib, Hassan Salim Al-Jumaily, Zainab Falah Hassan, Shokry F. Al-Saad

“…Earlier detection and treatment of dysfunction can delay or even prevent complications.…”
Get full text

Levothyroxine therapy in pregnancy: Are we overtreating patients? by Vesselina Yanachkova, Radiana Staynova, Daniela Grekova-Kafalova, Valentina Petkova

“…A lack of consensus in current guidelines on diagnosing thyroid dysfunction during pregnancy and administering levothyroxine raises concerns regarding treatment efficacy. …”
Get full text

Echocardiographic Changes in Patients with End-Stage Renal Disease at Initiation of Dialysis by Shabana Nazneen, Muzamil Latief, Manjusha Yadla

“…Patients with chronic kidney disease have a tremendous burden of cardiovascular disease (CVD), and patients with end-stage renal disease (ESRD) are at a greater risk of CVD and deaths. Materials and Methods: In this study, 245 incident dialysis patients were included, and none of the patient was on erythropoietin. …”
Get full text

Laboratory manifestations of fetal inflammatory response syndrome in extremely premature newborns by V.V. Bila

“…Fetal inflammatory response syndrome (FIRS) is a pathological response to changes in the chorion and is manifested by inadequate cytokine production and endothelial dysfunction. Objective of the study: to investigate laboratory changes in extremely premature newborns depending on the presence of FIRS criteria. …”
Get full text

Kencur Supplementation Modulates Interleukin-6 (IL-6) and C-Reactive Protein (CRP) in Response to Muscle Damage Following Eccentric Exercise by Roy Januardi Irawan, Joesoef Roepajadi, Heri Wahyudi, Noortje Anita Kumaat, Abdul Rohim Tualeka, Nanda Rimawati, Adi Wijayanto

“…Intense or unaccustomed exercise can cause muscle damage and tissue injury, leading to temporary muscle dysfunction and the release of pro-inflammatory cytokines and free radicals. …”
Get full text

Aspects of cytomegalovirus reactivation in critically ill patients by V. V. Gorbachev, T. I. Dmitrachenko, V. M. Semenov, S. K. Egorov

“…Despite the available evidence, data on reactivation in this group of patients are limited by the relatively small sample size, the variety of patient groups studied, the differences in study methodology, and the variability in reported results, which excludes the possibility of summarizing the results.This study aimed to determine the frequency of reactivation of cytomegalovirus infection in critically ill patients and to identify its main clinical features.Materials and methods. The study included 118 critically ill patients with severe bacterial and viral-bacterial infections accompanied by multiple organ dysfunction. …”
Get full text

Management of Adverse Effects in Testosterone Replacement Therapy by Basheer Basheer, Vishal Ila, Rodrigo Barros, Francesco Mesquita, Leonardo Seligra Lopes, Victor Fernandes Negris Lima, Luciano A. Favorito, Ranjith Ramasamy

“…ABSTRACT Purpose: This narrative review aims to provide the most updated knowledge regarding the treatment of adverse effects secondary to testosterone replacement therapy (TRT), such as gynecomastia, cardiovascular and hematologic risks, prostate health risk, and liver dysfunction risks. Materials and Methods: An extensive literature review was conducted, incorporating guidelines from the American Urological Association and the Endocrine Society. …”
Get full text

Effect of 8 weeks of high-intensity functional training (HIFT) on previous vascular factors and exercise enjoyment in women suffering from metabolic syndrome by Mina Behari Kia, Bahman Hasanvand

“…Introduction: Individuals with metabolic syndrome face a higher risk of developing cardiovascular disease compared to healthy individuals, attributed to endothelial dysfunction, increased blood lipids, and insulin resistance. …”
Get full text

Mental disorders in patients with cystic fibrosis by A. A. Klimenko, A. Yu. Aleksandrova

“…Cystic fibrosis (CF) is a genetic disease that leads to dysfunction of internal organs and significantly increases the risk of respiratory infections. …”
Get full text

Neglected and Large Defect of Extensor Hallucis Longus Tendon Injuries reconstructed by Double looping with Extensor Digitorum Longus by an Improvised Surgical Method by Makesh Ram Sriraghavan, Poornima Kumararja, Pavalan Louis

“…But in chronic cases or neglected EHL injuries, the patient develops EHL dysfunction causing a flexion deformity of the great toe at the level of the IP joint. …”
Get full text

Protein growth factors and myocardial remodeling in hypertension in men with psoriasis by V. A. Razin, Yu. N. Kurganova, A. S. Nesterov, I. M. Vorotnikov

“…Protein growth factors such as vascular endothelial growth factor and insulin-like growth factor are involved in the pathogenesis of hypertension and psoriasis, and endothelial dysfunction is also noted in these diseases. Despite extensive studies of these nosologies, there is still insufficient information about the nature of remodeling of the cardiovascular system in the case of a combination of these pathologies.Objective. …”
Get full text

Assessment of cardiac hemodynamics indicators in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor A1166C gene p... by O. Ya. Babak, M. M. Zaitseva

“…According to our study results, no differences in left ventricular diastolic dysfunction were found depending on angiotensin II type 1 receptor (A1166C) gene polymorphism in the examined patients. …”
Get full text

A study of serum calcium, phosphorous and magnesium level in hypothyroid cases by Arun Dhungana, Naveen Shreevastva, Subash Pant, Baburam Pokharel

“…Conclusions: Our study, suggests that there was a significant change in the levels of serum calcium, phosphorous, and magnesium in thyroid dysfunction. Assessing the level of serum calcium and phosphorous can be fairly used as an index of bone resorption. …”
Get full text

The patient with cognitive impairment in practice of the general practitioner by Margarita A. Morozova, Elizaveta K. Kucherova, George E. Rupchev, Andrey A. Alekseev

“…The formulation of the seven items of the MCI 7 questionnaire was based on patients' complaints about those aspects of cognitive dysfunction that are found in MCI. The linguistic form of the questions was as close as possible to everyday speech, each question had to be answered either ”Yes” or ”No”. …”
Get full text

Vaginal Vault Prolapse by Azubuike Uzoma, K. A. Farag

“…Vault prolapse repair rely on either the use of patient's tissue or synthetic materials and can be carried out abdominally or vaginally. …”
Get full text