Machine learning-based new classification for immune infiltration of gliomas. by Feng Yuan, Yingshuai Wang, Lei Yuan, Lei Ye, Yangchun Hu, Hongwei Cheng, Yan Li

“…Then, use DAVID to perform functional enrichment analysis for different immune subtypes. …”
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Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH by Tobias Obermann, Teri Sakshaug, Vishnu Vignesh Kanagaraj, Andreas Abentung, Mirta Mittelstedt Leal de Sousa, Lars Hagen, Antonio Sarno, Magnar Bjørås, Katja Scheffler

“…Our data identified moderate enrichment of OG in the genome that is mainly dependent on the genomic context and not affected by DNA glycosylase-initiated repair. …”
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Genome-Wide Identification, Evolution and Expression Analysis of <i>GRAS</i> Transcription Factor Gene Family Under Viral Stress in <i>Nicotiana benthamiana</i> by Keyan Yao, Shuhao Cui, Songbai Zhang, Hao Cao, Long He, Jie Chen

“…The <i>GRAS</i> gene family not only performs a variety of regulatory functions in plant growth and development but also plays a key role in the defense mechanisms of plants in response to environmental stresses. …”
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THE IMPACT OF ECONOMIC INFRASTRUCTURE INVESTMENT ON FOREIGN TRADE FLOWS: THE CASE OF SOUTH AFRICA by Nomfundo Portia Vacu-Ngqila

“…A well-functioning economic infrastructure is fundamental for sustainable economic growth in both developing and developed countries. …”
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Novel Cross-Species Salivary Gland-Parasympathetic Neuron Coculture System by Hsueh- Wu, Mohamed Ishan, Md Rashid, Hong- Liu, Nadja Zeltner

“…The parasympathetic nervous system is essential for salivary gland development and functionality. Parasympathetic neuron (parasymN) innervation is the main neural network that controls salivary secretion. …”
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Identification and expression analysis of TALE superfamily genes explore their key roles in response to abiotic stress in Brassica napus by Meili Xie, Xiaojuan Zhang, Kexin Liu, Zhixian Qiao, Xiaohui Cheng

“…Results In this study, we identified 74 TALE family genes distributed on 19 chromosomes in the B. napus genome using bioinformatics methods. …”
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Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction by Xue Han, Ruyi Zheng, Jiajia Zhang, Yanan Liu, Ze Li, Guoxuan Liu, Jianing Zheng, Weiqi Li, Zijun Liang, Mengyang Wang, Jie Yu, Qiaojuan Shi, Huazhong Ying, Guang Liang

“…We find a significantly increased OTUD1 expression in diabetic mouse hearts, and single-cell RNA sequencing shows OTUD1 mainly distributing in cardiomyocytes. Cardiomyocyte-specific OTUD1 knockout prevents cardiac hypertrophy and dysfunction in both type 2 and type 1 diabetic male mice. …”
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Protective Role of γδ T Cells in Different Pathogen Infections and Its Potential Clinical Application by Yueshui Zhao, Ling Lin, Zhangang Xiao, Mingxing Li, Xu Wu, Wanping Li, Xiaobing Li, Qijie Zhao, Yuanlin Wu, Hanyu Zhang, Jianhua Yin, Lingling Zhang, Chi Hin Cho, Jing Shen

“…In this review, we will focus on the various subgroups of γδ T cells (mainly Vδ1 T cells and Vδ2 T cells) which can induce multiple immune responses or effective functions to fight against common pathogen infections, such as Mycobacterium tuberculosis, Listeria monocytogenes, influenza viruses, HIV, EBV, and HBV. …”
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Target oxidative stress-induced disulfidptosis: novel therapeutic avenues in Parkinson’s disease by Junshi Zhang, Tingting Liu, Haojie Wu, Jianshe Wei, Qiumin Qu

“…Subsequently, the distribution of target genes with AUC > 0.7 in different cell types of the brain was analyzed. …”
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STATE STIMULATION OF TRANSFORMATION OF POWER INDUSTRY by V. A. Zubakin

“…In this article questions of transformation of architecture of power industry, and also the main restrictions are considered: absence in regulatory base of new opportunities for consumers; general system inefficiency; impossibility “to legalize” appearance of new subjects (active consumers and prosumers, operators of micropower supply systems and aggregators of the distributed power objects, various service organizations), and also to deregulate the relations between them, to standardize interaction interfaces with EEC, to transform the energy markets.In article it is offered for transition to new digital power to make corresponding changes to the legislation: to enter new type of participants of the market (the active consumer, an active power complex), operated intellectual connection carrying out the standard with the electrical power system, completely responsible for management of the power supply and thus having the minimum regulatory restrictions on organizational model of the work; to improve rules of functioning of trade systems for creation of the markets of the distributed power providing an effective exchange of goods and services between traditional participants of the markets and participants of new type; to enter possibility of application of technologies of the coordinated management of the distributed sources and consumers of energy, systems of storage of energy, means of regulation of loading (“aggregators”) for the purpose of increase of efficiency of their use and participation in the electric power and power markets, including rendering system services and performance of other functions in these markets (the pilot project of such system is realized under the leadership of the author of the present article by subsidiary PAO “Lukoil” “Energy and gas of Romania”); to increase technological and economic flexibility of conditions on reliability and quality of power supply, creation of possibility of a choice by the consumer of conditions of power supply necessary for him and the account them in cost; to enter the accounting of the opportunities given by “new” decisions, at an assessment, formation and implementation of investment programs of the adjustable companies (including introduction of a technique of an assessment of investment projects at possession cost on all life cycle of the decision); to replace cross subsidizing of the population by industrial consumers with mechanisms of address social support and / or with system of restriction of volumes of consumption on reduced rates (“соцнорма”); to refuse further deployment of system of subsidizing of power supply of one regions at the expense of consumers of other regions (as it leads to growth of inefficient power consumption in the subsidized regions, not provided with available generation and infrastructure); to change norms of technical regulation, norms of design on the basis of new technologies; to make changes to programs of development of the infrastructure organizations of power industry taking into account trends of diversification, decentralization, decarbonization and a digitalization; to provide possibility of stimulation, including tariff, implementation of regional programs (pilot and regular), aimed at the complex development of power industry on the basis of new approaches, technologies and the practician, and also the hi-tech companies of small and medium business providing development.…”
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FORMALIZATION OF THE PROBLEM OF TRANSPORT LOGISTICS OPTIMIZATION NETWORKS AT THE STAGE OF REENGINEERING by Vladimir Beskorovainyi, Lyudmyla Kolesnyk, Dmytro Yevstrat

“…The following tasks are solved in the article: review and analysis of the current state of the problem of supporting decision-making in the tasks of optimizing logistics networks at the stage of their reengineering; decomposition of the problem of optimization of logistics networks at the main stages of their life cycles; selection of a logical scheme of the reengineering process of the logistics network as a territorially distributed object; development of a mathematical model of the general problem of multi-criteria optimization of logistics networks according to indicators of economy, efficiency, reliability and survivability; selection of models for scalar multi-criteria evaluation of reengineering options, taking into account factors that are difficult to formalize, knowledge and experience of the decision-maker. …”
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Biocomposite Active Whey Protein Films with Thyme Reinforced by Electrospun Polylactic Acid Fiber Mat by Andreea (Lanciu) Dorofte, Iulia Bleoanca, Florentina Ionela Bucur, Gabriel Mustatea, Daniela Borda, Felicia Stan, Catalin Fetecau

“…The bi-layer films obtained were characterized by SEM, showing the distribution of the electrospun fiber mat and an increased thickness of the PLA layer from WF/G1 to WF/G4, while FTIR spectra showed the structural vibrations of the functional groups. …”
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Overview of Effects of Motor Learning Strategies in Neurologic and Geriatric Populations: A Systematic Mapping Review by Li-Juan Jie, PhD, Melanie Kleynen, PhD, Guus Rothuizen, MSc, Elmar Kal, PhD, Andreas Rothgangel, PhD, Susy Braun, PhD

“…Objective: To provide a broad overview of the current state of research regarding the effects of 7 commonly used motor learning strategies to improve functional tasks within older neurologic and geriatric populations. …”
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Explainable AI-driven assessment of hydro climatic interactions shaping river discharge dynamics in a monsoonal basin by Prashant Parasar, Akhouri Pramod Krishna

“…Leveraging hydroclimatic inputs from five coupled model intercomparison project phase 6 (CMIP6) general circulation models (GCM) under the high emissions shared socioeconomic pathway (SSP585) scenario, the model was trained and evaluated across four active gauging stations: Muri, Adityapur, Jamshedpur, and Ghatsila covering the period 1980 to 2022, with projections extending to 2100. The main findings of this study are (1) KAN demonstrated high predictive performance with root mean squared error (RMSE) values ranging from 42.7 to 58.3 m3/s, Nash–Sutcliffe efficiency (NSE) between 0.80 and 0.87, mean absolute error (MAE) between 28.9 to 52.7 and R2 values between 0.84 and 0.90 across stations. (2) SHAP based feature contribution analysis identified Relative humidity (hurs), specific humidity (huss), and temperature (tas) as key predictors, while (pr) showed limited contribution due to spatial inherent inconsistencies in GCM precipitation data. (3) The bootstrapped SHAP distributions highlighted substantial variability in feature importance, particularly for humidity variables, revealing station specific uncertainty patterns in model interpretation. (4) The KAN framework results indicate strong temporal alignment and physical realism, confirming KAN’s robustness in capturing seasonal discharge dynamics and extreme flow events under monsoon influence environments. (5) In this study KAN with SHAP (SHapley additive exPlanations) is implemented for hydrological modeling under monsoon-influenced and data-limited regions such as SRB, offering improved accuracy, functional precision and efficiency compared to traditional models. …”
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UKRAINE’S GLOBAL STATUS AS AN INDICATOR OF ITS CURRENT PROBLEMS AND OPPORTUNITIES by T. Deyneka, O. Shkurupii, N. Pedchenko, S. Tul, K. Verhal

“…The global status is defined as the relative position of countries in the system of international relations. The main factors that determine the global status of countries are economic development; achievements in science, technology and innovation; development of social spheres (health care, education, social protection); the outcome of distributing and exercising power within the state (domestic policy) as well as between states (foreign policy); the effectiveness of institutions; and governance efficiency in the field of environmental management. …”
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A COMPOSITION PATCH ANTENNA by S. A. Pogarsky, D. V. Mayboroda, S. M. Mykhaliuk

“…The optimal values of the main parameters of the structure, affecting the functionality of the antenna have been determined, including form factors of the slits (cut-ins), angular characteristics of the triangle-shaped slit, the dielectric constant of the substrate, and the separation from the ground level. …”
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Genome-wide identification and analysis of the FLA gene family in maize (Zea mays L.) and its expression in response to abiotic stresses by Yongyan Cao, Xuanxuan Chen, Bo Wei, Tuo Zeng, Hongcheng Wang, Bin Zhu, Xuye Du, Lei Gu

“…They were unevenly distributed across ten maize chromosomes, forming 14 pairs of fragment replication with no tandem duplication, revealing that segmental duplication might be the main driving force of the family expansion. …”
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Features of the species composition based on the trophic analysis of artificial woody plantations of the Kryvyi Rih mining and industrial district by Maksym Kvitko, Olena Lykholat, Tetyana Lykholat, Mykhailo Holubiev, Yuriy Lykholat

“…Woody ecosystems on the territory of the Kryvyi Rih mining and metallurgical region are very unevenly distributed. They are concentrated mainly in river banks, forest protection plantations, and artificial plantations of protective territories of settlements. …”
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Research progress in effects of biochar on transport of inorganic pollutants in soil by ZHANG Dong, LIU Xingyuan, ZHAO Hongting

“…The biomass for preparation of biochar had extensive sources, and the treatment is usually easy-operation, mainly thermochemical decomposition under a poor-oxygen condition. …”
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Exploring the Role of Bifenthrin in Recurrent Implantation Failure and Pregnancy Loss Through Network Toxicology and Molecular Docking by Shengyuan Jiang, Yixiao Wang, Haiyan Chen, Yuanyuan Teng, Qiaoying Zhu, Kaipeng Xie

“…Molecular docking analysis using AutoDock Vina was conducted to evaluate the binding affinity between BF and the four hub proteins, as well as several hormone-related receptors. Functional enrichment results indicated that the candidate genes were mainly involved in apoptotic and oxidative stress-related pathways. …”
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