Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses. by Andres Kriete, William J Bosl, Glenn Booker

“…This model is iteratively extended towards an adaptive response model by incorporating protective negative-feedback loop circuits. Time-lapse simulations of the adaptive response model uncover how transcriptional and translational changes, mediated by stress sensors NF-kappaB and mTOR, counteract accumulating damage and dysfunction by modulating mitochondrial respiration, metabolic fluxes, biosynthesis, and autophagy, crucial for cellular survival. …”
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A novel pulse-modulated closed-loop artificial pancreas based on intravenous administration of insulin and glucagon by Simon L. Goede, Victor H. Snels, Willem-Jan W. J. H. Berghuis, Jan P. C. Bernards, Urs Wyder

“…In most semi and closed loop control systems to mimic the action of a normal pancreas in diabetes patients, insulin is administered subcutaneously. …”
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Closed-loop rehabilitation of upper-limb dyskinesia after stroke: from natural motion to neuronal microfluidics by Honggang Wang, Junlong Guo, Yangqi Zhang, Ze Fu, Yufeng Yao

“…Abstract This review proposes an innovative closed-loop rehabilitation strategy that integrates multiple subdomains of stroke science to address the global challenge of upper-limb dyskinesia post-stroke. …”
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Formation of Fiber Tapers by Chemical Etching for Application in Chaotic Correlation Fiber Loop Ring Down Sensing by Tianlong Wu, Lingzhen Yang, Jun Tian, Jie Chen, Zhuang Liu, Linlin Fan, Weijie Ding, Juanfen Wang, Pingping Xue

“…In contrast to the previous demonstrations by using mode-locked fiber laser, this work is demonstrated to use chaotic laser combined with fiber loop ring down sensor. The formation and performance of fiber tapers was monitored by combining chaotic fiber ring down technology on line and in real time. …”
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Establishment and Evaluation of a Loop-Mediated Isothermal Amplification Assay for Detection of Raccoon Dog in Meat Mixtures by Jinhua Liu, Yanyu Shi, Siying Teng, Lianpeng Wu, Xinmin Zhang

“…In this study, we developed an easily applicable, rapid, and economically feasible method for identifying the presence of raccoon dog in meat mixtures based on loop-mediated isothermal amplification (LAMP). Four sets of LAMP primers were tested at different temperatures, and the primers that worked best at 62°C (set 2) were determined. …”
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Development of Au-Nanoprobes Combined with Loop-Mediated Isothermal Amplification for Detection of Isoniazid Resistance in Mycobacterium tuberculosis by Jutturong Ckumdee, Thongchai Kaewphinit, Kosum Chansiri, Somchai Santiwatanakul

“…Novel loop-mediated isothermal amplification (LAMP) can also detect drug resistance, which is a one-point mutation, by designing inner primers of 5′ end specific with the mutant. …”
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Wireless Optogenetic Microsystems Accelerate Artificial Intelligence–Neuroscience Coevolution Through Embedded Closed-Loop System by Sungcheol Hong

“…Furthermore, AI-driven real-time analysis facilitates closed-loop control, allowing experimental setups across a diverse range of scenarios. …”
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SCMAS: an IMU-based 6-DOF closed-loop permanent magnet actuation system for magnet agent by Yutan Chen, Dingwen Tong, Yiqun Zhao, Tao Chen, Xinjian Fan

“…In this paper, we present a three-degree-of-freedom (3-DOF) semi-open closed-loop magnetic actuation system (SCMAS) for generating static gradient magnetic fields and dynamic rotating magnetic fields. …”
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Spatiotemporal orchestration of calcium-cAMP oscillations on AKAP/AC nanodomains is governed by an incoherent feedforward loop. by Lingxia Qiao, Michael Getz, Ben Gross, Brian Tenner, Jin Zhang, Padmini Rangamani

“…In this work, we develop computational models of the Ca2+/cAMP pathway and AKAP/AC nanodomain formation that give rise to the two important predictions: instead of an arbitrary phase difference, the out-of-phase Ca2+/cAMP oscillation reaches Ca2+ trough and cAMP peak simultaneously, which is defined as inversely out-of-phase; the in-phase and inversely out-of-phase oscillations associated with Ca2+-cAMP dynamics on and away from the nanodomains can be explained by an incoherent feedforward loop. Factors such as cellular surface-to-volume ratio, compartment size, and distance between nanodomains do not affect the existence of in-phase or inversely out-of-phase Ca2+/cAMP oscillation, but cellular surface-to-volume ratio and compartment size can affect the time delay for the inversely out-of-phase Ca2+/cAMP oscillation while the distance between two nanodomains does not. …”
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CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops by Johannes W. Dietrich, Nina Siegmar, Jonas R. Hojjati, Oliver Gardt, Bernhard O. Boehm

“…Feedback loops and other types of information processing structures play a pivotal role in maintaining the internal milieu of living organisms. …”
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Detection of <i>Klebsiella pneumoniae</i> in Veterinary and Food Matrices Using Loop-Mediated Isothermal Amplification by Icía Bermúdez-Fornos, Alberto Cepeda, Alejandro Garrido-Maestu, Alexandre Lamas

“…This novel method was based on loop-mediated isothermal amplification (LAMP) and evaluated in real-time LAMP, as well as in end-point colorimetric LAMP. …”
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Improved cohesin HiChIP protocol and bioinformatic analysis for robust detection of chromatin loops and stripes by Karolina Buka, Zofia Parteka-Tojek, Abhishek Agarwal, Michał Denkiewicz, Sevastianos Korsak, Mateusz Chiliński, Krzysztof H. Banecki, Dariusz Plewczynski

“…Using comprehensive bioinformatic analysis, we show that a dual chromatin fixation method compared to the standard formaldehyde-only method, results in a substantially better signal-to-noise ratio, increased ChIP efficiency and improved detection of chromatin loops and architectural stripes. Additionally, we propose an automated pipeline called nf-HiChIP ( https://github.com/SFGLab/hichip-nf-pipeline ) for processing HiChIP samples starting from raw sequencing reads data and ending with a set of significant chromatin interactions (loops), which allows efficient and timely analysis of multiple samples in parallel, without requiring additional ChIP-seq experiments. …”
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Optimization of loop mediated isothermal amplification assay (LAMP) for detection of chloroquine resistance in P. vivax malaria by Davinder Kaur, Upninder Kaur, Chandra Kanta Bhusal, Vibhor Tak, Rakesh Sehgal

“…Molecular methods that are currently in use for detecting single nucleotide polymorphisms in resistant genes including Polymerase chain reaction (PCR), Realtime-Polymerase chain reaction require highly sophisticated labs and are time consuming. So, with this background the study has been designed to optimize Loop Mediated Isothermal Amplification Assay to detect single nucleotide polymorphisms in chloroquine resistance gene of Plasmodium vivax in field settings. …”
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A quite sensitive fluorescent loop-mediated isothermal amplification for rapid detection of respiratory syncytial virus by Yihong Hu, Zhenzhou Wan, Yonglin Mu, Yi Zhou, Jia Liu, Ke Lan, Chiyu Zhang

“…Methodology: Here, we established a highly sensitive and specific reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assay for the rapid detection of A and B group hRSV simultaneously. …”
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Closed-Loop Spinal Cord Stimulation in Chronic Pain Management: Mechanisms, Clinical Evidence, and Emerging Perspectives by Nicholas Mangano, Andrew Torpey, Catherine Devitt, George A. Wen, Christopher Doh, Abhishek Gupta

“…Closed-loop spinal cord stimulation represents a significant advancement by utilizing evoked compound action potentials to continuously modulate stimulation intensity in real-time, ensuring more stable and effective pain management. …”
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Lattice oxygen activity regulation by alkaline earth metals in iron oxides for biomass chemical looping gasification by Guangyao Yang, Wenjie Xu, Jingbo Jia, Changfu You, Haiming Wang

“…Biomass chemical looping gasification (BCLG) represents a highly promising approach for syngas production. …”
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Development and Verification of Sampling Timing Jitter Noise Suppression System for Phasemeter by Tao Yu, Ke Xue, Hongyu Long, Mingzhong Pan, Zhi Wang, Yunqing Liu

“…The heterodyne interference signal first passes through the quadrant photoelectric detector (QPD) to achieve photoelectric conversion, then passes through the analog-to-digital converter (ADC) to achieve analog and digital conversion, and finally passes through the digital phase-locked loop (DPLL) for phase locking. The sampling timing jitter of the heterodyne interference signal caused by the ADC is the main noise affecting the phase measurement performance and must be suppressed. …”
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Oscillations in First-Order, Continuous-Time Systems via Time-Delay Feedback by Abimael Salcedo, Joaquin Alvarez

“…A technique to generate (periodic or nonperiodic) oscillations systematically in first-order, continuous-time systems via a nonlinear function of the state, delayed by a certain time d, is proposed. …”
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Robust Stability Analysis and Synthesis for Switched Discrete-Time Systems with Time Delay by Liguo Zhang, Hongfeng Li, Yangzhou Chen

“…The problems of robust stability analysis and synthesis for a class of uncertain switched time-delay systems with polytopic type uncertainties are addressed. …”
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Controller Design for Continuous-Time Linear Control Systems with Time-Varying Delay by Hongli Yang, Lijuan Yang, Ivan Ganchev Ivanov

“…Furthermore, these criteria guarantee that the reachable set of the closed-loop system remains bounded within a prescribed ellipsoid under zero initial conditions. …”
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