Study design and procedures for a hybrid effectiveness-implementation incomplete stepped-wedge cluster-randomized trial to evaluate a differentiated point-of-care HIV diagnosis and... by Michael E. Herce, Caitlin Cassidy, Alexandra Munson, Jessie K. Edwards, Sarah E. Rutstein, Mitch Matoga, Chimwemwe Kumwenda, Katherine R. Simon, Joep J. van Oosterhout, Carrie M. Cox, Funny Kamanga, Wiza Kumwenda, Sam Phiri, Ethel Rambiki, Agness Thawani, Jacqueline Huwa, Bridget Malewezi, Tisu Mvalo, Agatha Bula, Lameck Chinula, Irving Hoffman, Madeleine A. Squibb, Rose K. Nyirenda, Friday Saidi, Mina C. Hosseinipour, Maganizo B. Chagomerana

“…Pregnant and breastfeeding women (PBFW) living with HIV frequently go without viral load (VL) monitoring and their infants miss key HIV testing milestones for early infant HIV diagnosis (EID). …”
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Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc by Tomoya Matsuo, Yoshiki Takeoka, Takashi Yurube, Takeru Tsujimoto, Yutaro Kanda, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Naotoshi Kumagai, Kohei Kuroshima, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani

“…In vivo study: The WB displayed sustained decreases in TRPV4 protein expression 2, 28, and 56 days after injection. Under the loaded condition, TRPV4 siRNA‐injected discs presented radiographic height loss ([−31.7, −7.75]), histomorphological damage ([0.300, 4.70]), and immunofluorescent suppression of autophagy ([1.61, 20.5]) and ECM metabolism ([−25.2, −6.41]) compared to control siRNA‐injected discs at 56 days. …”
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Prevalence of acquired resistance to antiretrovirals in children and adolescents living with HIV under clinical follow-up at the Roosevelt Hospital in Guatemala by S. Alonso, E. Salazar, N. Gálvez, J. Navas, C. Quintana, N. Orózco, L. Prieto, M.L. Navarro, S. Guillén, J.M. Gómez-Alba, C. Medina-Sánchez, J. Juarez, A. Holguín

“…Seventy-nine (79.8%) harbored viruses with DRM: 61 (61.6%) to NRTIs, 70 (70.7%) to NNRTIs and 6 (6.3%) to PIs (major DRMs). Half (52.5 %) presented dual resistance (NRTI+NNRTI) and 5.3 % triple (NRTI+NNRTI+PI). …”
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Challenges and Lessons Learned from a Field Trial on the Understanding of the Porcine Respiratory Disease Complex by Elisa Crisci, Andrew R. Kick, Lizette M. Cortes, John J. Byrne, Amanda F. Amaral, Kim Love, Hao Tong, Jianqiang Zhang, Phillip C. Gauger, Jeremy S. Pittman, Tobias Käser

“…NanoString was used to quantify 21 pathogens within the bronchoalveolar lavage (BAL) at the time of necropsy (51 dpv). PRRSV-2 was present in 53 out of 55 pigs, and the other five pathogens (PCMV, PPIV, <i>B. bronchiseptica</i>, <i>G. parasuis</i>, and <i>M. hyorhinis</i>) were detected in BAL samples. …”
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Antimicrobial activity and mechanistic insights of AMP-17 against drug-resistant Pseudomonas aeruginosa and its efficacy in wound infection management by Ruyu Tao, Ruyu Tao, Ruyu Tao, Chunren Tian, Chunren Tian, Chunren Tian, Chunren Tian, Ting Su, Ting Su, Ruxia Cai, Ruxia Cai, Ruxia Cai, Dongxu Song, Dongxu Song, Dongxu Song, Dongxu Song, Na Zhao, Na Zhao, Na Zhao, Na Zhao, Yuansan Lei, Yuansan Lei, Yuansan Lei, Zhenlong Jiao, Zhenlong Jiao, Zhenlong Jiao, Zhenlong Jiao, Guo Guo, Guo Guo, Guo Guo

“…In a murine wound infection model, AMP-17 displayed potent in vivo antimicrobial activity, significantly reducing bacterial load and downregulating pro-inflammatory cytokine expression, thereby effectively promoting wound healing. …”
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Anticholinergic drug exposure is associated with prevalence, worsening and incidence of dysphagia among hospitalized older adults by Lucia Muglia, Alessia Beccacece, Luca Soraci, Ramona Caloiero, Franco Arturi, Paolo Fabbietti, Mirko Di Rosa, Jacopo Sabbatinelli, Giada Ida Greco, Elvira Filicetti, Mara Volpentesta, Alberto Montesanto, Ersilia Paparazzo, Antonio Cherubini, Massimiliano Fedecostante, Chiara Chinigò, Maria Capalbo, Andrea Corsonello, Fabrizia Lattanzio

“…Results: Out of 4,005 patients included, 1,070 (30%) presented dysphagia at hospital admission. High anticholinergic burden was associated with increased prevalence of dysphagia at hospital admission (p < 0.001). …”
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Análisis tridimensional del proceso de granallado utilizando un modelo de múltiples impactos. // 3d shot peening process analysis using multiple impacts model. by M. A. Calle Gonzales, D. Benítez Barrios, E. Ângelo, E. Gonçalves

“…Esto trae como consecuencia positiva la reducción de los valores de las tensiones de tracción, principales<br />responsables por la propagación de eventuales fisuras presentes en el material del elemento de máquina o estructura. …”
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Optimal 2D Placement of Virtual Objects in Physical Space for Augmented Reality Applications by M. V. Alpatova, Yu. V. Rudyak

“…The solution was tested on gadgets in peak load mode for 5, 10, 15, 20, 25, 35, 40, 45, and 50 objects. 1.8 thousand devices were used for experiments. …”
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Evaluation of Cold Plasma on Physicochemical Properties of Rose Water by Zeinab Rahmani, Pasha Ahmadi, Reza Sharafati Chaleshtori

“…This research was designed to investigate the effect of atmospheric pressure cold plasma on the physicochemical properties and microbial load of rose water. Materials and MethodsIn this experimental research, a dielectric barrier discharge system was designed. …”
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Isolation and characterization of a protective monoclonal antibody targeting outer membrane protein (OmpA) against tuberculosis by Huoming Li, Jiahong Ji, Mengjin Qu, Xiuling Ma, You Zuo, Minghui Tang, Lingyuan Zeng, Hao Li

“…The abundant surface antigens present on the cell wall of Mtb can induce protective antibodies; however, its full characterization remains incomplete. …”
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Engineering of CD8+ T cells with an HIV-specific synthetic notch receptor to secrete broadly therapeutic antibodies for combining antiviral humoral and cellular immune responses by Lina Meng, Haichi Zhao, Shangkun Chang, Weiting Li, Yinghui Tian, Ruihong Wang, Libian Wang, Tiejun Gu, Jiaxin Wu, Bin Yu, Chu Wang, Xianghui Yu

“…The synNotch receptor-expressing cells can sense the viral antigen presented on both HIV-1 particles and the surface of target cells. …”
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Comparación de dos dispositivos de medición de potencia y trabajo durante ejercicio de fuerza con tecnología inercial flywheel (Comparison of two power and work data acquisition sy... by Luis Manuel Martínez Aranda, Rodrigo Fernández Gonzalo

“… El objetivo del presente estudio fue comparar los valores de potencia y trabajo obtenidos en tiempo real mediante los sistemas BlueBrainTM y SmartCoachTM, durante ejercicio de fuerza en una prensa de piernas equipada con tecnología inercial flywheel, usando diferentes inercias (cargas). …”
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Un Nuevo Método de Identificación Basado en la Respuesta Escalón en Lazo Abierto de Sistemas Sobre-amortiguados by Luis A. Mora, Jhon E. Amaya

“…Abstract: In this paper a new process identification method based in open loop step response of overdamped systems is presented. Initially the transient behavior of transfer functions with multiple real poles is analyzed, establishing analytical formulas to estimate the time it takes for these systems to reach certain points of his reaction curve to stimuli of the step type, including settling time for error criteria of 2% and 5%. …”
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Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions by Nurlan Zhangabay, Aizhan Zhangabay, Kenzhebek Akmalaiuly, Akmaral Utelbayeva, Bolat Duissenbekov

“…In this connection, this study presents a parametric assessment of the influence of climatic and geometric factors on the aerodynamic characteristics of the air cavity, which affect the heat exchange process in the ventilated layer of curtain wall systems. …”
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Environmental Contamination and Mining Impact: Physico-Chemical and Biological Characterization of Propolis as an Indicator of Pollution in the Roșia Montană Area, Romania by Mirel Glevitzky, Roxana Bostan, Mihaela Laura Vică, Gabriela-Alina Dumitrel, Mihai-Teopent Corcheş, Maria Popa, Ioana Glevitzky, Horea-Vladi Matei

“…Contamination with heavy metal ions from mining activities presents a major environmental issue. This study investigates pollution caused by heavy metals from mining, with a particular emphasis on toxic ions and essential ions for living organisms. …”
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Monkeypox virus (MPXV) isolation from longitudinal samples of 11 patients to infer risk of onwards transmission by Dr Helen Callaby, Dr Janie Olver, Ms Kirsty Emery, Dr Kevin Richards, Dr Marian Killip, Dr Natalie Groves, Dr Jake Dunning, Professor Malcolm G Semple, Professor J Kenneth Baillie, Dr Tommy Rampling, Dr Catherine F Houlihan

“…The sample was from a 40-50 year old man with poorly controlled HIV CD4+ T-lymphocyte count 57 cells/mm3. HIV viral load 52,800 copies/ML) who presented with an ulcerating rash affecting limbs and a necrotic tongue lesion. …”
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Pádel: una mirada compleja, dinámica y no lineal en la iniciación deportiva y el entrenamiento (Paddle-tennis: a complex, dynamic and non-linear approach for teaching-learning pro... by Enrique Lacasa Claver, Cristòfol Salas Santandreu, Carlota Torrents Martin

“…By comparing the workload of the small-sided situation vs. regular game, it is suggested that physical load can even be increased. The benefits of these proposals are discussed, considering the differences with approaches based on isolating the player from the key and specific perception-action links of padel. …”
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Introduction by Jerzy F. Latka

“…Water causes the bonds between the fibre molecules to break, thus turning paper into pulp, which will lose the physical properties essential for load-bearing structures, such as strength and stiffness. …”
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A Single-Chain Mpox mRNA Vaccine Elicits Protective Immune Response in Mice by Qian Xu, Rong-Rong Zhang, Mei Wu, Jie Zhang, Zu-Xin Wang, Hang Chi, Chao Zhou, Xiao-Chuan Xiong, Hai-Tao Liu, Cheng-Feng Qin, Qing Ye

“…The protective efficacy of the candidate vaccines was evaluated based on body weight monitoring and tissue viral load measurement after challenge with vaccinia virus (VACV). …”
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Neuroprotective Effects of Inhaled Xenon for Sedation Compared With Propofol Intravenous Sedation in Severe Ischemic Stroke by O. A. Grebenchikov, A. K. Evseev, V. V. Kulabuchov, A. N. Kuzovlev, S. S. Petrikov, G. R. Ramazanov, Sh. Gh. Khusainov, R. A. Cherpakov, A. K. Shabanov, A. I. Spichko

“…Long-lasting motor and cognitive impairments, a decrease in the level of consciousness over time aggravate the course of the disease, leading to immobilization syndrome and comorbidity load, which contributes to the development of life-threatening conditions in this category of patients. …”
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