Seasonal dynamics of nutrients concentration and dissolved oxygen content in the rivers of southern Primorye by Anna S. Vazhova

“…However, natural seasonal variation of nutrients is distorted by anthropogenic load for some rivers with industrial and agricultural activity in the basins, including the territories of P.R. …”
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Synthesis and properties of 3-(ethylthio)-9-methyl-6-(alkylthio)pyrazolo[1,5-d][1,2,4]triazolo[3,4-f][1,2,4]triazines by S. O. Fedotov, A. S. Hotsulia

“…Taking into account the presented facts, the creation of new compounds in a number of pyrazolo-triazole condensed systems is scientifically attractive with endowed features of practical significance and relevance. …”
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Disulfidptosis related immune genes drive prognostic model development and tumor microenvironment characterization in bladder urothelial carcinoma by Shenchao Guo, Guangjia Lv, Hengyue Zhu, Yangyang Guo, Ke Yin, Haibo Yu, Hewei Zhang

“…Immune checkpoints, cell infiltration, and tumor mutation load were assessed. Differential gene enrichment analysis was conducted. …”
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Likelihood of Leveraging Augmented Reality Technology to Promote HIV Prevention and Treatment Among Adolescent Girls and Young Women in Cameroon: Cross-Sectional Survey by Zhao Ni, Intan Maharani Sulistyawati Batubara, Jackson Jr Nforbewing Ndenkeh, Georges Bediang, Habakkuk Yumo, Xuehong Zhang, Sunyong Oh, Yuchen Zhao, LaRon E Nelson

“…Future research should focus on exploring the preferred features of AR-based digital health interventions and consider methods of implementing them in the context of Cameroon or SSA.…”
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A reduced-carbohydrate and lactose-free formulation for stabilization among hospitalized children with severe acute malnutrition: A double-blind, randomized controlled trial. by Robert H J Bandsma, Wieger Voskuijl, Emmanuel Chimwezi, Greg Fegan, André Briend, Johnstone Thitiri, Moses Ngari, Laura Mwalekwa, Victor Bandika, Rehema Ali, Fauzat Hamid, Betty Owor, Neema Mturi, Isabel Potani, Benjamin Allubha, Anneke C Muller Kobold, Rosalie H Bartels, Christian J Versloot, Marjon Feenstra, Deborah A van den Brink, Patrick F van Rheenen, Marko Kerac, Celine Bourdon, James A Berkley

“…Secondary outcomes included in-hospital mortality, diarrhea, and biochemical features of malabsorption and refeeding syndrome. The trial was registered at clinicaltrials.gov (NCT02246296). …”
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Morphological and immunohistochemical analysis of tumor-infiltrating lymphocytes, M2 macrophages, BCL 6 and SOX10 in the tumor microenvironment of nodular cutaneous melanoma by K. S. Titov, A. A. Markin, E. I. Schurygina, N. S. Karnaukhov, D. A. Zaryanov, D. N. Bubenko

“…This fact can be explained by immunogenicity of cutaneous melanoma, high mutational load, as well as features of its tumor microenvironment, where in most cases high infiltration by immunocompetent cell is observed. …”
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Engineered NiO/TiO2 and CuO/NiO/TiO2 heterojunctions for sustainable direct photocatalytic epoxidation of propylene using molecular oxygen by Nicola Morante, Katia Monzillo, Alessandro Padua, Andrea Muscatello, Diana Sannino, Serena Esposito, Vincenzo Vaiano

“…Among the NiO/TiO2 series, the NiO(1.1%)/TiO2 composite exhibited the lowest photoluminescence intensity, indicating reduced electron–hole recombination, while UV–Vis DRS analysis revealed a red shift in the absorption onset and a reduction in the band gap energy. These features resulted in enhanced light absorption and facilitated charge transfer, leading to superior photocatalytic performance compared to lower and higher NiO loadings. …”
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From detection to intervention: An end-to-end system for recognizing the “signal for help” gesture in real-time by Federico Buccellato, Eleonora Vacca, Sarah Azimi, Corrado De Sio, Luca Sterpone

“…Despite its potential, its effectiveness has been impeded by limited public awareness, the risk of misinterpretation, and the lack of reliable automated detection systems.To address these challenges, this paper introduces a framework consisting of two interconnected components: a real-time detection system of the “Signal for Help” gesture using a machine learning-based recognition system and a custom mobile application that receives notifications from the detection system and alerts security personnel in real-time.During the development process, we faced several challenges, including detecting the gesture in crowded environments and keeping the computational load low to ensure the system could run efficiently on edge devices.We overcame these challenges by designing a system that combines hand tracking and feature extraction, using tools such as MediaPipe and DeepSORT, followed by a final classification step. …”
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Comparative life cycle assessment of alternative scenarios for municipal solid waste management (case study: Babol, Iran) by Gholamreza Nabi Bidhendi, Maryam Rabiee Abyaneh, Omid Hassanzadeh Moghimi

“…The comparative analysis of the six scenarios underscores the fact that the lower potential environmental loads were related to the 4th scenario in all the impact categories. …”
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2′-Fucosyllactose mitigates cognitive deficits in Alzheimer models: targeting amyloid pathology, oxidative stress, and synaptic plasticity by Yeasmin Akter Munni, Khoa Nguyen Tran, Seon-Min Jeon, Meeyul Hwang, Jong-Won Yoon, Young-Ha Song, Tae Woo Oh, Tae Woo Oh, Sang Il Gum, In-Jun Yang

“…These findings indicate that 2′-FL modulates multiple pathological features relevant to AD in preclinical models.…”
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Key Characteristics and Examples of Digital Educational Content for an International Online Platform by Olesya V. Berseneva, Elena G. Doroshenko, Pavel S. Lomasko, Irina V. Trusey

“…As well as the limitations of cognitive load in terms of the number of semantic units on the screen and the inclusion of the social component as an opportunity to communicate with real native speakers through audio and video messages in the forum. …”
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ECM-mimicking composite hydrogel for accelerated vascularized bone regeneration by Guanglong Li, Fei Gao, Donglei Yang, Lu Lin, Weijun Yu, Jiaqi Tang, Ruhan Yang, Min Jin, Yuting Gu, Pengfei Wang, Eryi Lu

“…Furthermore, functional aptamers (Apt19S and AptV) are readily attached to the DNA network to recruit bone marrow mesenchymal stem cells (BMSCs) and achieve sustained release of loaded vascular endothelial growth factor towards angiogenesis. …”
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Pathology-inspired collagen-binding thermosensitive micelle drops enable prolonged and efficient treatment of fungal keratitis by Maoyu Cai, Haiping Zhong, Xindi Wang, Liangpin Li, Xueyan Zhou, Yan Wang, Xia Hua, Shutao Guo, Xiaoyong Yuan

“…Inspired by the unique pathological features of corneal ulcers, we report a thermosensitive multifunctional eye drop, designated PX-TA, based on a poloxamer (PX) and a collagen-adhesive tannic acid (TA), for prolonged and efficient treatment of FK. …”
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The MHC-I-dependent neoantigen presentation pathway predicts response rate to PD-1/PD-L1 blockade by Yuchen Zhang, Chen Yang, Yanchao Xu, Xiang Jiang, Jiajun Shi, Binghua Li, Decai Yu

“…Importantly, combining antigen expression, processing, presentation, and recognition features provides superior predictive power compared to TMB alone. …”
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Machine learning algorithms to predict the risk of admission to intensive care units in HIV-infected individuals: a single-centre study by Jialu Li, Yi Ding, Yiwei Hao, Chengyu Gao, Jinjing Xiao, Ying Liu, Yining Zhao, Qinlan Li, Lulu Xing, Hongyuan Liang, Liang Ni, Fang Wang, Sa Wang, Di Yang, Guiju Gao, Jiang Xiao, Hongxin Zhao

“…The ANN model performed best in internal validation (Brier score = 0.034, ROC-AUC = 0.961, PR-AUC = 0.895) to predict the risk of ICU admission for PLWHs. 11 important features were identified to predict predict ICU admission risk by the Shapley plot: respiratory failure, multiple opportunistic infections in the respiratory system, AIDS defining cancers, baseline viral load, PCP, baseline CD4 cell count, and unexplained infections. …”
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A Novel Dynamic Growth Rod Inducing Spinal Growth Modulation for the Correction of Spinal Deformities by Yangyang Xu, Da Lu, Le Zhang, Shijia Zhang, Yong Wu, Heng Li, Baoqing Pei, Xueqing Wu

“…We applied a compressive load of 400 N to test axial stiffness and a moment of 1 NM to assess bending stiffness under six different conditions. …”
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The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism by Mai-dong Li, Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan, Yue-yin Pan

“…BackgroundBreast cancer is characterized as highly heterogenous and is a representative model to understand how molecular features of tumor biology determine therapeutic strategy. …”
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Use of murine model to study virulence of epidemically significant Mycobacterium tuberculosis genotypes and to evaluate effectiveness of chemotherapy by Dr Igor Mokrousov, Prof. Tatiana Vinogradova, Dr. Marine Dogonadze, Dr. Natalia Zabolotnykh, Dr. Marina Dyakova, Dr. Dilyara Esmedlyaeva, Dr. Maria Vitovskaya, Dr Olga Rubtsova, Dr Sergei Chekrygin, Dr Anna Vyazovaya, Prof. Boris Ariel

“…After 2 and 5.5 months of therapy, groups of mice were euthanized and studied for bacterial load, histology, lung pathology, and biochemical markers of liver damage. …”
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Spatial variations in PM2.5 composition and source apportionment across six cities of Jiangxi, China: insights from the 2023–2024 new year haze episode by Qineng Wang, Qineng Wang, Wei Deng, Xiang Tu, Jiao Wang, Dan He, Yuanjun Gong, Zhaofeng Tan, Keding Lu

“…Based on local emission patterns and topographic features and the component concentration differences of PM2.5, we speculate that there are three regional patterns: (1) Northern cities, characterized by high loadings of NO3− (industrial), OM (VOCs-derived), and SO42− (promoted by lake air masses with high humidity); (2) Central cities, dominated by local agricultural NH4+ and conversion from industrial gaseous sources precursors enhanced by local photochemistry; (3) Southern Jiangxi, where vehicular NOx-to-NO3− conversion predominated, exacerbated by topographic stagnation from the Nanling Mountains. …”
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Anti-hyperglycemic and toxicological effects of a traditional polyherbal formulation, Athamathurot, used at Bantakhun hospital, Thailand by Acharaporn Issuriya, Palika Wetchakul, Surasak Limsuwan, Siriwimol Jiwpraditkul, Patcharawalai Jaisamut, Thammarat Kaewmanee, Jo Aan Goon, Sineenart Sanpinit

“…Atha-D was given daily at doses of 50–500 mg/kg p.o. for 28 days to investigate its cumulative toxic effect. Histopathological features of internal organs and hematological and biochemical parameters were examined. …”
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