FEATURES OF REGULATION OF ERYTHROPOIESIS IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 5D by E. S. Lapina, M. M. Batjushin, R. A. Belovolova, I. V. Sarvilina, V. N. Poganeva

“…The aim: to study features of the cytokine profile in patients with chronic kidney disease receiving treatment by programmed hemodialysis. Materials and methods: the study included 100 patients aged 53,4 ± 15,8 years with chronic kidney disease stage 5D, receiving hemodialysis. …”
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Assessment of ambulance interventions; proposal of a performance measurement framework for healthcare improvement in EMS response to patient collapse by Kamran Idris, Zainab Mubeen, Zeeshan Noor Shaikh, Aswad Latif, Shaheryar Hasan, Arshia Khan

“…The framework was pilot-tested for one year from January to December 2023, where its use was limited to the cases of patient collapse in ambulances, also referred to as out-of-hospital deaths. …”
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Too young to pour: the global crisis of underage alcohol use by Susanna Esposito, Beatrice Rita Campana, Alberto Argentiero, Marco Masetti, Valentina Fainardi, Nicola Principi

“…Although various prevention strategies have demonstrated short-term benefits (particularly those involving active parental involvement and skill-based school programs), long-term effectiveness is limited due to inconsistent implementation, lack of standardization, and inadequate policy enforcement. …”
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The Prevalence of Toxoplasma gondii in Saudi Arabia (1994–2023): A Systematic Review and Meta-Analysis by Hassan N. Moafa, Abdullah H. Altemani, Ali Alaklabi, Khalid Y. Ghailan, Alkhansa Alshabi, Majid Ahmed Darraj, Hammad Ali Fadlalmola

“…Targeted educational programs and public health interventions are essential to raise awareness and reduce the risk of T. gondii infection. …”
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Gender-specific differences in mental health literacy and influencing factors among residents in Foshan City, China: a cross-sectional study by Zhaosong Chu, Jianling Xie, Rui Liu, Liqin Ou, Zheng Lan, Guojun Xie

“…When developing relevant policies as well as measures, it is imperative to take into account gender differences and implement tailored programs aimed at enhancing MHL among both male and female residents.…”
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Understanding and Practice of AWaRe Among Healthcare Professionals in a Tertiary Care Hospital in Nepal; Implications for Antimicrobial Resistance: A Comparative Study by Sitaram Khadka, Suchit Thapa Chhetri, Reshu B. K., Krishna Kumar Sah, Arav Mehra, Rinku Joshi

“…Targeted educational programs could address existing knowledge gaps and strengthen antimicrobial stewardship efforts in resource‐limited settings like Nepal.…”
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Management Practices and Financial Performance of Church of Uganda-Founded Private Secondary Schools in Greater Ankole Dioceses by Mwebembezi, Atheria.K

“…Recommendations include capacity-building programs for school administrators, the adoption of participative leadership models, and the development of diversified funding streams through community engagement and partnerships. …”
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Generative AI/LLMs for Plain Language Medical Information for Patients, Caregivers and General Public: Opportunities, Risks and Ethics by Pal A, Wangmo T, Bharadia T, Ahmed-Richards M, Bhanderi MB, Kachhadiya R, Allemann SS, Elger BS

“…There could be a risk that people may share their medical information with AI/LLMs, which could get into the wrong hands. To make sure these programs really help people, they need to be clear about how they work, and they must have good rules to follow and take advice from doctors and patients to improve performance. …”
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Balancing ethics and conservation: Assessing short‐term behavioral impacts of biopsy sampling in a recovering whale population by Leena Riekkola, Simon Childerhouse, Rochelle Constantine, Ros Cole, Robert Harcourt, Dorothea Heimeier, Dave Lundquist, Catherine Meyer, Mike Ogle, Debbie Steel, Esther Stuck, Aimee van derReis, Emma L. Carroll

“…Abstract Long‐term monitoring programs based on individual identification have provided a sound basis for monitoring the status of endangered and recovering species. …”
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Exploring gender dynamics in climate-smart agriculture adoption: a study in semi-arid Dodoma, Tanzania by Mahlet Degefu Awoke, Mahlet Degefu Awoke, Mahlet Degefu Awoke, Katharina Löhr, Katharina Löhr, Anthony A. Kimaro, Marcos Lana, Boris D. Soh Wenda, Kwabena Buabeng, Kwabena Buabeng, Johannes Michael Hafner, Johannes Michael Hafner, Stefan Sieber, Stefan Sieber

“…Female-headed households face unique barriers, such as smaller landholdings, labor constraints, and limited access to credit, training, and group membership. …”
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Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models by Jian Ye, Brian A Belt, Shuyang S Qin, Rachel Jewell, Laura M Calvi, Bradley N Mills, Tara G Vrooman, Carl J Johnston, Scott A Gerber, Angela L Hughson, Gary Hannon, Maggie L Lesch, Jim Eyles, Nadia Luheshi, Noah A Salama, Sidney Lesser, Sarah L Eckl, Lauren Benoodt, Edith Lord, David Linehan

“…Anti-LIF antibody therapy has demonstrated safety and tolerability but limited efficacy in phase 1 clinical trial in advanced solid tumors. …”
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Census of Lyα Emission from ∼600 Galaxies at z = 5–14: Evolution of the Lyα Luminosity Function and a Late Sharp Cosmic Reionization by Yuta Kageura, Masami Ouchi, Minami Nakane, Hiroya Umeda, Yuichi Harikane, Shintaro Yoshiura, Kimihiko Nakajima, Hidenobu Yajima, Tran Thi Thai

“…We present the statistical properties of Ly α emission in 586 galaxies at z  = 4.5–14.2, observed by multiple JWST/NIRSpec spectroscopy projects, including the JADES, GLASS, CEERS, and GO/DDT programs. We obtain Ly α equivalent width (EW), Ly α escape fraction, and ionizing photon production efficiency measurements or upper limits for these galaxies, and confirm that the Ly α -emitting galaxy fraction decreases toward higher redshifts. …”
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dCas9-SPO11-1 locally stimulates meiotic recombination in rice by Léo Herbert, Aurore Vernet, Aurore Vernet, Julien Frouin, Julien Frouin, Anne Cécile Meunier, Anne Cécile Meunier, Jeremy Di Mattia, Minghui Wang, Gaganpreet K. Sidhu, Luc Mathis, Alain Nicolas, Alain Nicolas, Emmanuel Guiderdoni, Emmanuel Guiderdoni, Ian Fayos

“…DiscussionThese results open new avenues to locally stimulate meiotic recombination in crop genomes and paves the way for a future implementation in plant breeding programs.…”
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Molecular and serological evidence of chikungunya virus among dengue suspected patients in Sri Lanka by Mya Myat Ngwe Tun, Maurine Mumo Mutua, Shingo Inoue, Yuki Takamatsu, Satoshi Kaneko, Takeshi Urano, Rohitha Muthugala, Lakkumar Fernando, Menaka Hapugoda, YINS Gunawardene, Kouichi Morita

“…Despite its potential for severe long-term effects, surveillance for CHIKV remains limited, especially in dengue-endemic region like Sri Lanka. …”
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Consistent trends from different methods for monitoring SARS-CoV-2 in urban wastewater during a 29-month longitudinal study by Janine McCalder, Janine McCalder, Jangwoo Lee, Jangwoo Lee, Judy Qiu, Qiaozhi Li, Linnet Immaraj, Nicole Acosta, María A. Bautista, Melissa Wilson, Barbara Waddell, Kristine Du, Aito Ueno, Rhonda Clark, Rhonda Clark, Alexander Krusina, Danielle A. Southern, Tyler Williamson, Tyler Williamson, Chloe Papparis, Paul Montesclaros, Lance Non, September Stefani, Gail Visser, Puja Pradhan, Norma Ruecker, John Conly, John Conly, John Conly, John Conly, John Conly, John Conly, Steve Hrudey, Kevin Frankowski, Bonita Lee, Bonita Lee, Michael D. Parkins, Michael D. Parkins, Michael D. Parkins, Xiaoli Pang, Xiaoli Pang, Casey R. J. Hubert

“…Multiple studies have compared different protocols but have been limited by short periods of observation or low numbers of test sites. …”
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Immunogenic Properties of a Novel Hepatitis A Vaccine Candidate Based on a Fast-Growing Viral Strain by Maria Isabel Costafreda, Malén Massot-Cladera, Gemma Chavarria-Miró, Alba Arrebola, Àngels Franch-Masferrer, Maria J. Rodríguez-Lagunas, Adán Martínez-Velázquez, Albert Blanco, Albert Bosch, Susana Guix, Margarida Castell, Rosa Maria Pintó

“…The novel HM175-HP-based vaccine would therefore facilitate mass vaccination programs and prevent vaccine shortages.…”
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Pre-treatment peripheral blood TCR repertoire as a predictor of response in patients with NSCLC treated with immunochemotherapy by Yong Yang, Hui-yu Jiang, Yuan Li, Fang Wu, Zhao-yang Chen, Guo-ping Zheng, Wen-Zhong Su, Hai-long Wang, Min Pang

“…Methods Blood samples were collected from patients with advanced NSCLC before initiating anti-programmed cell death 1 (anti-PD-1) antibody treatment in combination with chemotherapy. …”
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Genomic and Transcriptomic Analysis to Explore the Biological Characteristics of <i>Cyclocybe chaxingu</i> by Qiang Yang, Haiyan Song, Ge Su, Xuncheng Wang, Haijing Hu, Zhijun Zhai, Minghui Chen, Jianping Zhou, Hua Yin, Yang Gao, Dianming Hu

“…Despite its importance, molecular and genetic breeding studies on <i>C. chaxingu</i> have been limited by the lack of comprehensive genomic information. …”
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Diabetes Fact Sheets in Korea 2024 by Se Eun Park, Seung-Hyun Ko, Ji Yoon Kim, Kyuho Kim, Joon Ho Moon, Nam Hoon Kim, Kyung Do Han, Sung Hee Choi, Bong Soo Cha

“…Therefore, early intervention programs, education, and strategies tailored to younger populations are urgently required.…”
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Trends of malaria incidence, prevalence, mortality, and disability-adjusted life years in Eastern Africa region from 1990 to 2021: a systematic analysis from Global Burden of Disea... by Taye Abuhay Zewale, Leltework Yismaw Wondmagegn, Habtamu Abebe Getahun, Mengistie Kassahun Tariku, Anemaw Asrat Achamyeleh, Mulusew Andualem Asemahagn, Wondemagegn Enbiale, Tesfaye B. Mersha, Essey Kebede Muluneh, Awoke Misganaw Temesgen

“…Despite extensive control efforts, ineffective programs, limited treatment access, and low distribution of artemisinin-based combination therapy, contribute to the persistent challenges. …”
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