Huanglian Jiedu Decoction Treats Ischemic Stroke by Regulating Pyroptosis: Insights from Multi-Omics and Drug–Target Relationship Analysis by Yixiao Gu, Zijin Sun, Tao Li, Xia Ding

“…<b>Background:</b> Ischemic stroke (IS) is a severe condition with limited therapeutic options. Pyroptosis, a type of programmed cell death linked to inflammation, is closely associated with IS-related damage. …”
Get full text

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy. by Deepika Dogra, Van Anh Phan, Sinan Zhang, Cezar Gavrilovici, Nadia DiMarzo, Ankita Narang, Kingsley Ibhazehiebo, Deborah M Kurrasch

“…SLC13A5 individuals respond poorly to treatment options; yet drug discovery programs are limited due to a paucity of animal models that phenocopy human symptoms. …”
Get full text

Outlook of Present Organic Agriculture Policies and Future Needs in Sri Lanka by S.H. Pushpa Malkanthi

“…Current organic farming programs need to be revised in order to formulate policies covering all areas related to production, handling, processing, certification, labeling and marketing, in order to bring the benefits of organic agriculture to farmers, marketers and consumers in a fair manner.…”
Get full text

Studying how state health services delivery policies can mitigate the effects of disasters on drug addiction treatment and overdose: Protocol for a mixed-methods study. by Matthew D Eisenberg, Alexander McCourt, Elizabeth A Stuart, Lainie Rutkow, Kayla N Tormohlen, Michael I Fingerhood, Luis Quintero, Sarah A White, Emma Elizabeth McGinty

“…In response to the COVID-19 pandemic, U.S. states implemented multiple policies designed to mitigate disruptions to addiction treatment and overdose prevention services, for example policies expanding access to addiction treatment delivered via telehealth and policies designed to support continuity of naloxone distribution programs. There is limited evidence on the effects of these policies on addiction treatment and overdose. …”
Get full text

Innovative approaches in physical education: leveraging cognitive activation to boost student outcomes by Haoran Zha, Xia Ding, Wenye Li

“…Educational programs should therefore integrate CATS to boost classroom success while also developing comprehensive, multi-faceted interventions to cultivate emotional skills and promote the transfer of healthy habits beyond the school setting.…”
Get full text

Effect of depression and empowerment on medication adherence in patients with breast cancer: a descriptive survey by Sookyung Jeong, Eun Jeong Kim

“…However, comprehensive studies remain limited, especially in Korea. This study explores the effects of depression and empowerment on medication adherence among patients with breast cancer undergoing anti-hormonal therapy. …”
Get full text

ChatGPT for Univariate Statistics: Validation of AI-Assisted Data Analysis in Healthcare Research by Michael R Ruta, Tony Gaidici, Chase Irwin, Jonathan Lifshitz

“…ConclusionsChatGPT shows promise as a tool for exploratory data analysis, particularly for researchers with some statistical knowledge and limited programming expertise. However, its application requires careful prompt construction and human oversight to ensure accuracy. …”
Get full text

Characteristics and antibiotic resistance patterns of urinary tract isolates in hospitalized and non-hospitalized patients: a cross-sectional study in Khartoum, Sudan by Samah El-Arifi, Eltayeb AbdAlla, El Sheikh Mahgoub, Bothyna Fadol, Rashida Elmubarak

“…Continuous monitoring, development of local antibiograms, and implementation of surveillance programs are essential for guiding empirical antibiotic use and managing UTIs effectively, especially in resource-limited settings like Sudan.…”
Get full text

Awareness of colon cancer screening among the general population: Community-based study from the Qassim Region of Saudi Arabia by Mohammed D. Aldakhil, Abdullah S. Alayaaf, Nibras M. Alamro, Omar K. Aljubaili

“…Although a substantial proportion of participants demonstrated knowledge about the risk factors, symptoms, and prevention of CRC, there is limited knowledge about screening programs in the region. …”
Get full text

Drivers of hygienic menstrual practices among reproductive-age women: evidence from Nepal demographic health survey-2022 by Nihal Hasan, Pradeep Kumar, Rahul Rajak

“…Abstract Background Exclusive use of hygienic methods during menstruation has not received adequate attention in Nepal, with limited research utilizing nationally representative data. …”
Get full text

Primary care pediatricians’ involvement in influenza vaccination campaign in Italy by Rosaria Indaco, Francesca Leoni, Costantino Panza, Paolo Giorgi Rossi

“…Future strategies should focus on strengthening logistical support, tailored training and parent communication, and promoting shared models of care to enhance effectiveness and sustainability of vaccination programs.…”
Get full text

A METHOD OF COMPUTER SIMULATION MODELING OF USER AND BOT BEHAVIOR IN A RECOMMENDATION SYSTEM USING THE GRAPH DATABASE NEO4J by Yelyzaveta Meleshko, Mykola Yakymenko, Viktor Bosko

“…The methods used are: graph theory, theory of complex networks, statistics theory, probability theory, methods of object-oriented programming and methods of working with graph databases. …”
Get full text

Immunotherapy in cervical cancer: an innovative approach for better treatment outcomes by Treshita Dey, Sushma Agrawal

“…Checkpoint inhibitors targeting programmed death-1 (PD-1) and its ligand (PD-L1) have shown promising results in patients with advanced or recurrent cervical cancer. …”
Get full text

Nurses’ Experiences of Providing Dysphagia Services Through the Internet+Nursing Service Care Model: Qualitative Study by Zhifang Ren, Ling Tong, Shuojin Fu, Shuai Jin, Yanling Wang, Qian Xiao

“…While nurses acknowledge the value of this care model, addressing staffing shortages, improving training programs, and strengthening regulatory frameworks are essential for optimizing service delivery. …”
Get full text

Therapeutic Potential of Injectable Supramolecular Hydrogels With Neural Stem Cell Exosomes and Hydroxypropyl Methylcellulose for Post-Stroke Neurological Recovery by Zhang Q, Wang Y, Zhu Z, Ahmed W, Zhou D, Chen L

“…Behavioral assessments and immunofluorescence staining demonstrated that exosomes significantly promoted angiogenesis and nerve regeneration in stroke-affected areas, thereby reversing programmed cell death.Conclusion: The Exo-HPMC nanohydrogel presents a groundbreaking approach for stroke therapy. …”
Get full text

Digital transformation in start-ups: a bibliometric analysis by Aswathy Sreenivasan, M. Suresh

“…Design/methodology/approach – The research only looked into account papers that mentioned the ((“Digital transformation”) AND (“Startups”) OR (“Entrepreneurship”) OR (“Entrepreneur”)) for the title, abstract and keywords. The R programming language's Biblioshiny package was considered for thoroughly examining the papers. …”
Get full text

Healthcare professionals face ethical challenges in managing care for neurodevelopmental disorders: a qualitative study in Lebanon by Mustafa Saleh, Hani Chanbour, Lara Saoudi, Ingrid Nader, Maryse Hayek

“…Further research is needed to develop training programs for HCPs that address these ethical challenges and promote patient-centred decision-making.…”
Get full text

Group Stable Matching Problem in Freight Pooling Service of Vehicle–Cargo Matching Platform by Linlin Kong, Min Huang

“…Since this model is a mixed-integer linear programming model with relatively few decision variables but a large number of constraints, this paper introduces the cutting-plane algorithm. …”
Get full text

Cumulative Risk Assessment of Dietary Exposure to Pesticide Residues in Brown Rice (Oryza sativa L.) from the Three Main Rice-Growing Regions in China during 2016–2020 by Zhenzhen Cao, Xiaolong Zheng, Meiyan Guan, Wanyue Zhang, Xiaoyan Lin, Xiaohua Zhao, Mingxue Chen

“…The overall detection rate and over the maximum residue limit (MRL) rate of pesticides in brown rice decreased from 39.15% and 3.59% in 2016 to 34.11% and 1.53% in 2020, respectively. …”
Get full text

Patient Experiences with Hearing Aids in South African Public Healthcare by Katijah Khoza-Shangase, Theresa-Joy Munyembate

“…Furthermore, policy interventions that incorporate tele-audiology, community-based maintenance programs, and integrated healthcare approaches are crucial in ensuring sustainable hearing healthcare outcomes.…”
Get full text