Genetic assessment of farmed Oreochromis mossambicus populations in South Africa by Mahlatse Fortunate Mashaphu, Gordon Craig O’Brien, Colleen Thelma Downs, Sandi Willows-Munro

“…The study suggests that select farmed populations may have the potential for use in breeding and broodstock supplementation programs but emphasizes the importance of thorough genetic monitoring. …”
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TMTP1-modified polymeric micelles for the inhibition of ovarian cancer metastasis and recurrence through enhanced photothermal-immunotherapy by Ling Wang, Jie Li, Danya Zhang, Songwei Tan, Guiying Jiang, Xueqian Wang, Fei Li, Ying Zhou, Pingbo Chen, Rui Wei, Ling Xi

“…Moreover, PTT with TP1-IM nanomicelles in combination with programmed cell death ligand 1 (PD-L1) checkpoint blockade could induce strong anti-tumor immune responses, relieve the immunosuppressive tumor microenvironment, and thus effectively inhibit the metastasis of OC. …”
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Thrombosis, Translational Medicine, and Biomarker Research: Moving the Needle by Joseph R. Shaw, Stephan Nopp, Benedicte Stavik, Kimberley Youkhana, Alison L. Michels, Soetkin Kennes, Janusz Rak, Hugo ten Cate

“…Dedicated translational science training programs geared toward educating physicians on the appropriate measurement, interpretation, and integration of biomarker data in clinical practice should foster endorsement by frontline physicians. …”
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A core curriculum for pediatric lung ultrasound: an expert consensus by Anna Maria Musolino, Lorenzo Di Sarno, Danilo Buonsenso, Paolo Tomà, Gian Luigi Natali, Caterina Bock, Maria Alessia Mesturino, Simona Scateni, Antonio Corsello, Antonio Chiaretti, Alberto Villani, Rino Agostiniani

“…However, unlike some other medical specialties, structured ultrasound training is not consistently integrated into pediatric residency programs, resulting in variable skill acquisition among national practitioners. …”
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Sensory acceptance and biological implications of volatile compounds in Mexican soybean germplasm by Mónica López-Fernández, Octelina Castillo-Ruíz, Benjamín Abraham Ayil-Gutiérrez, Homar Rene Gill-Langarica

“…However, consumer acceptance of these products is limited by undesirable flavors, largely attributed to lipoxygenase activity. …”
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Tricuspid Valve Replacement in a Patient with a Leadless Cardiac Pacemaker: Current Guidelines and Recommendations for Perioperative Management by River Hames, J. W. Awori Hayanga, Diane Schmidt-Krings, Timothy Goldhardt, John Bozek, Donald Siddoway, Stanley Schmidt, John Lobban, Heather K. Hayanga

“…The perioperative management of patients with these devices has been underreported; we thus seek to add to the limited body of knowledge of perioperative management of patients with leadless cardiac pacemakers. …”
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Smoking attitudes, self-reported practices, and COPD knowledge among adults aged 20–59 years: Insights from a Japanese sample by Yolanda De Fatima De Oliveira Graca, Liu Yang, Cui Mingyu, Afsari Banu Alpona, Taeko Watanabe, Yuko Sawada, Emiko Tanaka, Tokie Anme

“…Among smokers who attempted to quit, 27.7% expressed willingness to quit, but only 3.0% were interested in cessation programs. Conclusions A proportion of participants had a smoking history, highlighting tobacco use prevalence. …”
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Enhanced recovery after surgery-guided strategies in single-incision laparoscopic totally extraperitoneal hernioplasty for inguinal hernia: a narrative review by Yi Jin, Hongqun Zhang, Yuping Chen, Chunyan Zhang, Yan Lin, Zhuoyin Wang

“…Standardized training programs and AI-assisted surgical systems may address existing technical barriers to widespread adoption.…”
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EgoFall: Real-Time Privacy-Preserving Fall Risk Assessment With a Single On-Body Tracking Camera by Chiao-Yi Wang, Faranguisse Kakhi Sadrieh, Yi-Ting Shen, Giovanni Oppizzi, Li-Qun Zhang, Yang Tao

“…Therefore, real-time individual fall risk assessment is essential for designing more effective fall prevention programs and developing advanced home-based training solutions. …”
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Development of genome-wide insertion/deletion markers and genetic diversity in Sipunculus nudus along the Beibu Gulf of China by Yuzhu Ni, Chunli Han, Yating Liu, Manman Li, Weijie He, Jialin Yang, Jie Zou, Huijing Peng, Pengliang Wang

“…This delineation of population substructure provides critical insights for optimizing selective breeding programs and formulating germplasm conservation strategies in S. nudus.…”
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Factors associated with knowledge in African immigrants with personal experiences of dementia by Manka Nkimbeng, Truphosa (Posa) Aswani, Elle Albers, Wynfred N. Russell, Tetyana P. Shippee, Joseph E. Gaugler

“…African immigrants who seek community care only have limited dementia knowledge.…”
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Advancing Knowledge on Machine Learning Algorithms for Predicting Childhood Vaccination Defaulters in Ghana: A Comparative Performance Analysis by Eliezer Ofori Odei-Lartey, Stephaney Gyaase, Dominic Asamoah, Thomas Gyan, Kwaku Poku Asante, Michael Asante

“…Integrating such models into routine immunization programs could enable data-driven targeting of high-risk groups, supporting policymakers in strategies to close vaccination coverage gaps.…”
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Designing Green Architecture Building that Blend with the Nature by Sunil Kumar, Gaurav Shukla, Nimesh Raj, Shikhar Gupta, Swarna Swetha Kolaventi, Esther Kiruba, Trilochan Jena

“…Government regulations pertaining to energy and water use as well as CO2 emissions will need to include mandatory limitations. The performance of existing buildings can be enhanced by a number of important sustainability improvements, in addition to energy and water efficiency, such as structural evaluation, resource use, disaster resilience, waste reduction through recycling programs, sustainable procurement and purchasing practices, and continuing operations and maintenance practices. …”
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Smoking during pregnancy; an epidemiologic study of knowledge and behavior in Caucasian women by Victoria Maria Ruta, Teodora Gabriela Alexescu, Nicoleta Stefania Motoc, Roxana Constantin, Daisy Vaida-Voevod, Milena Adina Man

“…Both passive and active smoking during pregnancy is a serious health problem that must be addressed through rigorous health programs, which must include (but not necessarily be limited to) behavioral therapy.…”
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Disaster vulnerability hotspots in the Portland metro-region: Converging indices for equitable resilience by Idowu Ajibade, Matthew Walter, Jason Sauer, Aswatha Raghunathasami, James M. Done, Paul Loikith, Chris Lower, Heejun Chang, Arun Pallathadka, Mae E. Sowards, Ming Ge

“…In Clackamas, vulnerability was due to limited hospital access, weak infrastructure and institutions, mobile homes, and inadequate community resources. …”
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Biology, Ecology, and Management of Prevalent Thrips Species (Thysanoptera: Thripidae) Impacting Blueberry Production in the Southeastern United States by Rosan Adhikari, David G. Riley, Rajagopalbabu Srinivasan, Mark Abney, Cera Jones, Ashfaq A. Sial

“…However, the brief flowering period limits the establishment of biological control agents. …”
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Prodrug-based combinational nanomedicine remodels lipid metabolism for reinforced ferroptosis and immune activation by Ling Lin, Zaixiang Fang, Guohao Liu, Yiwei Liu, Zhiqian Li, Dayi Pan, Yunkun Li, Hemi Kang, Xiaoding Shen, Jingyao Zhang, Qiyong Gong, Kui Luo, Jing Jing

“…Ferroptosis is a form of programmed cell death characterized by overwhelmed lipid oxidation, and it has emerged as a promising strategy for cancer therapy. …”
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Evaluating bioassay efficacy of extremophile bacillus species for environmentally safe control of Aedes aegypti larvae by Alaa A. Alnahari, Abdulaziz M. Kusa, Ahmad K. AL-Ghamdi, Basim Algashgari, Shatha I. Alqurashi, Jazem A. Mahyoub, Mohammed N. Baeshen

“…In contrast, B. licheniformis and B. stercoris exhibited limited efficacy, requiring significantly higher doses to achieve comparable results. …”
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STS2 deficiency revives CD8+T cells from exhaustion and augments checkpoint blockade efficacy in cancer immunotherapy by Chunxiao Li, Fei Ma, Ying Zhang, Ting Wang, Hongnan Mo, Ning Zhong, Dongkui Xu, Fangzhou Sun, Yantong Zhou, Jianbin Guo, Zhenguo Zhao, Xiaoqi Yang, Haili Qian

“…Background T-cell exhaustion is a major barrier to effective antitumor immunity and limits the efficacy of cancer immunotherapies. This study investigates the role of suppressor of T-cell signaling 2 (STS2, also known as UBASH3A) in regulating CD8+ T-cell exhaustion within the tumor microenvironment.Methods We used genetic ablation of STS2 in mouse models to assess tumor control and responses to anti-programmed cell death protein 1 (PD-1) checkpoint blockade therapy. …”
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Quantitative systems toxicology modeling in pharmaceutical research and development: An industry‐wide survey and selected case study examples by Kylie A. Beattie, Meghna Verma, Richard J. Brennan, Diana Clausznitzer, Valeriu Damian, Derek Leishman, Mary E. Spilker, Britton Boras, Zhenhong Li, Elias Oziolor, Theodore R. Rieger, Anna Sher

“…The survey suggests high demand for QST models and resource limitations were indicated as a common obstacle to broader use and impact. …”
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