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161
Inhibition of MERS-CoV papain-like protease by sunitinib: In vitro and in silico investigations
Published 2025-04-01“…Middle East Respiratory Syndrome Coronavirus (MERS-CoV) remains a significant public health threat, with high mortality rates and no approved antiviral therapies. The papain-like protease (PLpro) of MERS-CoV plays a critical role in viral replication and immune evasion, making it a key target for drug discovery. …”
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162
Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis
Published 2025-02-01“…The expression of TNFAIP6 in human RA fibroblast-like synovial cell line MH7A was detected by RT-qPCR and Western blotting under simulated inflammatory environment. …”
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163
Mathematical simulation of railway track and trackside contamination with silt
Published 2015-04-01“…Transportation of ores suggests partial entrainment of dust particles from the top granular layer 10 - 15 cm thick; electrified lines add dust-like particles of copper contact wires, which turn to a fixed form as hydroxides. …”
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164
Simulation of a multimaterial model for modified auxetic structures
Published 2023-10-01“… Auxetic structures, which is a term used to describe materials with a negative Poisson’s ratio, show beneficial properties like a low density, a high energy absorption capacity and an increased indentation resistance. …”
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165
Fuzzy Pheromone Potential Fields for Virtual Pedestrian Simulation
Published 2016-01-01“…The study of collective movement of pedestrians is crucial in various situations, such as evacuation of buildings, stadiums, or external events like concerts or public events. In such situations and under panic conditions, several incidents and disasters may arise, resulting in loss of human lives. …”
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166
Similarities and Differences Between Natural and Simulated Slow Earthquakes
Published 2024-07-01“…We use spatio‐temporal slip potency rate data derived from Global Navigation Satellite System (GNSS) position time series in the Cascadia subduction zone and numerical simulations intended to reproduce their pulse‐like behavior and scaling laws. …”
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167
Magnetic domain walls interacting with dislocations in micromagnetic simulations
Published 2024-11-01“…Here, we implement dislocation stress fields in micromagnetic simulations through the induced anisotropy fields by inverse magnetostriction. …”
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168
Modular and extendable 1D-simulation for microfluidic devices
Published 2024-11-01“…There is a need for a more versatile and adaptable tool that covers novel applications, like mixing and the addition of membranes, and allows easy extension, resulting in one comprehensive 1D simulation tool for microfluidic devices. …”
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169
Simulation of open quantum systems on universal quantum computers
Published 2025-06-01“…In this work, we present an innovative and scalable method to simulate open quantum systems using quantum computers. …”
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170
Atomistic simulations of out-of-equilibrium quantum nuclear dynamics
Published 2025-04-01“…We benchmark the method with both a simple one-dimensional model to test its accuracy and a realistic 40-atom cell of SrTiO3 under THz laser pump, paving the way for simulations of ultrafast THz-Xray pump-probe spectroscopy like those performed in synchrotron facilities.…”
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171
Nonlocality of Tropical Cyclone Activity in Idealized Climate Simulations
Published 2017-12-01“…This low is modified by an SST‐induced change of a Walker‐like planetary circulation.…”
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172
Persistence and Burn-in in Solar Coronal Magnetic Field Simulations
Published 2025-01-01“…A challenge to quantifying simulation burn-in is that the underlying solar processes and data, like many physical phenomena, are non-Markovian and exhibit long memory or persistence and, therefore, their analysis evades standard statistical approaches. …”
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173
Design and Simulation of a Solar Thermal Dryer for Fruits.
Published 2024“…The write-up presented in this report focused on the design and manufacture of a solar thermal dryer for fruits that dries 5Kg of fruit slices, 5mm thick per batch, and can be used for small-scale farmers that grow fruits in western Uganda following a challenge they face like pests and disease infestation during open sun drying, nutrient loss and among others. …”
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174
Elevator Control Simulation Using Fuzzy Logic Management
Published 2024-12-01“…Detent force, one issue with stabilization systems, will be examined in terms of how well it functions under a fuzzy logic controller using a nonlinear test like changes in load and distance to obtain a policy suitable for application in the industrial sector or other human endeavors. …”
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175
Strategy Analysis of Seamlessly Resolving Turbulent Flow Simulations
Published 2025-06-01“…This paper presents a strict analysis of strategies for the design of seamlessly resolving turbulent flow simulations for a wide class of turbulence models. The essential conclusions obtained are the following ones: First, by construction, usually applied methods like DES are incapable of systematically spanning the range from modeled to resolved flow simulations, which implies significant disadvantages. …”
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176
Hydrogen Diffusion in Garnet: Insights From Atomistic Simulations
Published 2025-02-01“…Tracer simulations focusing on H alone highlight the vital role of atomic vibrations of heavier atoms like Mg on the release of H atoms. …”
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177
The calculus simulation to predict reliably heat transfer coefficient
Published 2025-06-01“…The corrugated tube is like straight tube, consists of short straight section and corrugated section, which can strengthen effect of the heat transfer because of changing fluid field resulting from the corrugated section. …”
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178
Experiences of student nurses with the booking and use of a multidisciplinary clinical simulation laboratory for self-directed simulation learning at a higher education institution
Published 2025-01-01“…However, student nurses’ access to a clinical teaching and learning facility like a multidisciplinary clinical simulation laboratory is hindered by several factors that impact negatively on the use of this teaching and learning facility for self-directed simulation-based learning (SSL). …”
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179
The Transition to Double‐Celled Circulations in Mock‐Walker Simulations
Published 2024-07-01“…The transition is associated with the development of a mid‐tropospheric minimum in the radiative‐subsidence velocity over the cold pool of the simulations, and is likely reinforced by zonal moisture and temperature fluxes between the warm and cold pools. …”
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180
LLM-based robot personality simulation and cognitive system
Published 2025-05-01“…Based on the proposed methods, our designed robot, Mobi, is enable to chat based on its own personality, handle social conflicts and understand user’s intent. Such simulations can achieve a high degree of human likeness, characterized by conversations that are flexible and imbued with intention.…”
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