Ambulance attendances involving personality disorder – investigation of crisis-driven re-attendances for mental health, alcohol and other drug, and suicide-related events by JH Broadbear, RP Ogeil, M McGrath, DS Scott, Z Nehme, F Moayeri, D Lubman, S Rao

“…Methods: We conducted a retrospective study of coded electronic patient care records from the Victorian-arm of the National Ambulance Surveillance System between January 2012 and May 2019. …”
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The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima. by Ariel D Chipman, David E K Ferrier, Carlo Brena, Jiaxin Qu, Daniel S T Hughes, Reinhard Schröder, Montserrat Torres-Oliva, Nadia Znassi, Huaiyang Jiang, Francisca C Almeida, Claudio R Alonso, Zivkos Apostolou, Peshtewani Aqrawi, Wallace Arthur, Jennifer C J Barna, Kerstin P Blankenburg, Daniela Brites, Salvador Capella-Gutiérrez, Marcus Coyle, Peter K Dearden, Louis Du Pasquier, Elizabeth J Duncan, Dieter Ebert, Cornelius Eibner, Galina Erikson, Peter D Evans, Cassandra G Extavour, Liezl Francisco, Toni Gabaldón, William J Gillis, Elizabeth A Goodwin-Horn, Jack E Green, Sam Griffiths-Jones, Cornelis J P Grimmelikhuijzen, Sai Gubbala, Roderic Guigó, Yi Han, Frank Hauser, Paul Havlak, Luke Hayden, Sophie Helbing, Michael Holder, Jerome H L Hui, Julia P Hunn, Vera S Hunnekuhl, LaRonda Jackson, Mehwish Javaid, Shalini N Jhangiani, Francis M Jiggins, Tamsin E Jones, Tobias S Kaiser, Divya Kalra, Nathan J Kenny, Viktoriya Korchina, Christie L Kovar, F Bernhard Kraus, François Lapraz, Sandra L Lee, Jie Lv, Christigale Mandapat, Gerard Manning, Marco Mariotti, Robert Mata, Tittu Mathew, Tobias Neumann, Irene Newsham, Dinh N Ngo, Maria Ninova, Geoffrey Okwuonu, Fiona Ongeri, William J Palmer, Shobha Patil, Pedro Patraquim, Christopher Pham, Ling-Ling Pu, Nicholas H Putman, Catherine Rabouille, Olivia Mendivil Ramos, Adelaide C Rhodes, Helen E Robertson, Hugh M Robertson, Matthew Ronshaugen, Julio Rozas, Nehad Saada, Alejandro Sánchez-Gracia, Steven E Scherer, Andrew M Schurko, Kenneth W Siggens, DeNard Simmons, Anna Stief, Eckart Stolle, Maximilian J Telford, Kristin Tessmar-Raible, Rebecca Thornton, Maurijn van der Zee, Arndt von Haeseler, James M Williams, Judith H Willis, Yuanqing Wu, Xiaoyan Zou, Daniel Lawson, Donna M Muzny, Kim C Worley, Richard A Gibbs, Michael Akam, Stephen Richards

“…For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…Data extraction Initial coding of the documents used both inductive (codes emerging through data analysis) and deductive methods (codes determined prior to analysis through initial programme theory and stakeholder discussions). …”
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Identifying and delineating the type 2 diabetes population in the Netherlands using an all-payer claims database: characteristics, healthcare utilisation and expenditures by Dirk Ruwaard, Henk J G Bilo, Rose J Geurten, Arianne M J Elissen, Jeroen N Struijs, Chantal van Tilburg

“…The healthcare utilisation of the Dutch type 2 diabetes population is distributed across the health system and utilisation of medical specialist care is high. This is likely to be due to presence of concurrent morbidities and complications. …”
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Genomic Characterization and Molecular Epidemiology of Tusaviruses and Related Novel Protoparvoviruses (Family <i>Parvoviridae</i>) from Ruminant Species (Bovine, Ovine and Caprine... by Fruzsina Tóth, Péter Pankovics, Péter Urbán, Róbert Herczeg, Ervin Albert, Gábor Reuter, Ákos Boros

“…This study reports the full-length coding sequences (~4400–4600 nt) of three novel tusavirus-related protoparvoviruses from ovine (“misavirus”, PV540792), for the first time bovine (“sisavirus”, PV540793) and subsequently from caprine (“gisavirus” PV540850/51) fecal samples, using next-generation sequencing (NGS) and PCR techniques. …”
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Comprehensive characterization of lncRNA N6-methyladenosine modification dynamics throughout bovine skeletal muscle development by Cui Mao, Wei You, Yuta Yang, Haijian Cheng, Xin Hu, Xianyong Lan, Enliang Song

“…However, the genome-wide methylation of long non-coding RNAs (lncRNAs) and its implications for the development of skeletal muscle remain poorly understood. …”
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Health vulnerabilities of participants to a Christian religious mass gathering event, a retrospective analysis by Alexandra Haută, Paul Lucian Nedelea, Radu-Alexandru Iacobescu, Mihaela Corlade-Andrei, Cristina-Mihaela Ghiciuc, Vladimir Poroh, Vasile Lucian Boiculese, Carmen Diana Cimpoeşu

“…Yet in univariate analysis, male gender and the elderly cohort were more likely to be coded during triage with moderate severity and receive further hospital care (OR-2.15, P = 0.012 and OR-1.81, P = 0.038 for men; OR-2.58, P = 0.002 and OR-1.86, P = 0.03 for elderly). …”
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Implementation outcomes from a randomized, controlled trial of a strategy to improve integration of behavioral health and primary care services by Constance van Eeghen, Jeni Soucie, Jessica Clifton, Juvena Hitt, Brenda Mollis, Gail L. Rose, Sarah Hudson Scholle, Kari A. Stephens, Xiaofei Zhou, Laura-Mae Baldwin

“…A practice survey score was high (met expectations) if its average was ≥ 4 on a scale 1-5; all other data were coded dichotomously, with high = 1. Results Regarding acceptability, 74% (14) of practices had high scores for willingness of providers and staff to use the Toolkit and 68% (13) for quality improvement teams liking the Toolkit. …”
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Activity-based funding of hospitals and its impact on mortality, readmission, discharge destination, severity of illness, and volume of care: a systematic review and meta-analysis. by Karen S Palmer, Thomas Agoritsas, Danielle Martin, Taryn Scott, Sohail M Mulla, Ashley P Miller, Arnav Agarwal, Andrew Bresnahan, Afeez Abiola Hazzan, Rebecca A Jeffery, Arnaud Merglen, Ahmed Negm, Reed A Siemieniuk, Neera Bhatnagar, Irfan A Dhalla, John N Lavis, John J You, Stephen J Duckett, Gordon H Guyatt

“…Decision-makers considering ABF should plan for likely increases in post-acute care admissions, and be aware of the large uncertainty around impacts on other critical outcomes.…”
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Identifying the diagnostic gap of tardive dyskinesia: an analysis of semi-structured electronic health record data by Kira Griffiths, Yida Won, Zachery Lee, Lu Wang, Christoph U. Correll, Rashmi Patel

“…Patients with a recorded diagnosis of TD were identified based on the presence ICD-9/10 codes within structured portions of medical records: ICD-9: 333.85; ICD-10: G24.01. …”
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Self-Disclosure and Social Support in a Web-Based Opioid Recovery Community: Machine Learning Analysis by Yu Chi, Huai-yu Chen, Khushboo Thaker

“…Posts containing informational self-disclosure were more likely to receive advice (β=0.17, PPPPPPP ConclusionsThis study highlights the role of self-disclosure in fostering social support within web-based OUD recovery communities. …”
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A novel intronic variant in the ASAH1 gene enhances aberrant splicing, causing spinal muscular atrophy with progressive myoclonic epilepsy by Jinli Bai, Ping Li, Hui Jiao, Yuwei Jin, Hong Wang, Qinglin Jiang, Fang Song, Xiaoyin Peng, Yujin Qu

“…Abstract Background Spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME) is a rare autosomal recessive disorder caused by ASAH1 gene variants. Although ASAH1 coding variants cause SMA-PME, the impact of noncoding variants, particularly noncanonical splice-site variants, is less clear. …”
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Barriers and facilitators to scaling up medications for opioid use disorder in Kentucky: qualitative perspectives of treatment organization staff by Hannah K. Knudsen, Shaquita Andrews-Higgins, Sandra Back-Haddix, Michelle R. Lofwall, Laura Fanucchi, Sharon L. Walsh

“…A consensus-based approach to coding and thematic analysis was used. Results Although some agencies had a fairly static number of patients, most described recent experiences with modest growth in MOUD census and the ability to provide same day/next day MOUD. …”
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Proposed changes to framework to assess contraceptive autonomy based on phased in-depth interviews in northwest Tanzania by Sheridan F. Bowers, Valencia J. Lambert, Aneth Nzali, Anna Samson, Nelusigwe Mwakisole, Hidaya Yahaya, Radhika Sundararajan, Samuel E. Kalluvya, Agrey H. Mwakisole, Jennifer A. Downs

“…Interviews were digitally recorded, transcribed verbatim, translated into English, and independently coded by two investigators. Results A total of 72 women were interviewed. …”
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Prevalence and factors influencing low social support from family, friends, and significant others among people with mental illness attending psychiatric outpatient clinics in Gond... by Wondale Getinet Alemu, Lillian Mwanri, Clemence Due, Telake Azale, Anna Ziersch

“…However, people with mental illness are less likely to receive adequate social support to overcome mental health challenges when compared with the general population. …”
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Understanding the uptake of virtual care for first and return outpatient appointments in child and adolescent mental health services: a mixed-methods study by Leslie Anne Campbell, Sharon E Clark, Jill Chorney, Debbie Emberly, NJ Carrey, Alexa Bagnell, Jaime Blenus, Miriam Daneff, John Charles Campbell

“…Between waves, return appointments were more likely to be virtual than first appointments. Interview participants (n=48) reported facilitators and barriers to virtual care within the CFIR domains of ‘outer setting’ (eg, external policies, client needs and resources), ‘inner setting’ (eg, communications within the service), ‘individual characteristics’ (eg, personal attributes, knowledge and beliefs about virtual care) and ‘intervention characteristics’ (eg, relative advantage of virtual or in-person care).Conclusions Shared decision-making regarding treatment modality (virtual vs in-person) requires consideration of client, caregiver, clinician, appointment, health system and public health factors across episodes of care to ensure accessible, safe and high-quality mental healthcare.…”
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p62 mRNA suppresses NLRP1 expression in cutaneous SCC cells through miR-34a-5p by Paulina Hennig, Patrick Turko, Michela Di Filippo, Mitchell P. Levesque, Thomas Kündig, Hans-Dietmar Beer

“…Although miR-34a-5p seems to bind neither p62 nor NLRP1 mRNA directly, it increases NLRP1 expression, most likely through an indirect and complex mechanism, which occurs at the RNA level. …”
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Disease trajectory and competing risks of patients with cirrhosis in the US. by Mohsen Mohammadi, Bima J Hasjim, Salva N Balbale, Praneet Polineni, Alexander A Huang, Mitchell Paukner, Therese Banea, Oriana Dentici, Dominic J Vitello, Joy E Obayemi, Andrés Duarte-Rojo, Satish N Nadig, Lisa B VanWagner, Lihui Zhao, Sanjay Mehrotra, Daniela P Ladner

“…Overall, patients in advanced stages of cirrhosis were more likely to die than they were to receive a LT, suggesting that patients should be referred and waitlisted for LT earlier in the disease process.…”
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Renal hyperfiltration is associated with a reduced incidence of hypertension in individuals younger than 70 by Hee-Jung Ha, Min Kyoung Kang, Jeong Hwa Kim, Youn-Hee Choi, Tae-Jin Song

“…The association between renal hyperfiltration and a lower risk of hypertension incidence was likely to vary with age.…”
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The Role of Cytokine Gene Polymorphisms in Rehabilitation Outcome After Traumatic Brain Injury by Franca Rosa Guerini, Cristina Agliardi, Milena Zanzottera, Antonio Caronni, Laura Antolini, Chiara Camilla Derchi, Tiziana Atzori, Elisabetta Bolognesi, Jorge Navarro, Mario Clerici, Angela Comanducci

“…Genetic polymorphisms in cytokine-coding genes may influence cytokine expression, thereby affecting rehabilitation and prognosis. …”
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