All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. by Andrew J Schork, Wesley K Thompson, Phillip Pham, Ali Torkamani, J Cooper Roddey, Patrick F Sullivan, John R Kelsoe, Michael C O'Donovan, Helena Furberg, Tobacco and Genetics Consortium, Bipolar Disorder Psychiatric Genomics Consortium, Schizophrenia Psychiatric Genomics Consortium, Nicholas J Schork, Ole A Andreassen, Anders M Dale

“…We show a consistent pattern of enrichment of polygenic effects in specific annotation categories across diverse phenotypes, with the greatest enrichment for SNPs tagging regulatory and coding genic elements, little enrichment in introns, and negative enrichment for intergenic SNPs. …”
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ChatGPT Integration in Higher Education: Impacts on Teaching and Professional Development of University Professors by Elmedina Nikoçeviq-Kurti , Lirika Bërdynaj-Syla

“…Data from email interviews were analyzed according to thematic analysis, with codes organized into broad themes to identify patterns and relationships. …”
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Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution. by Marieke C Verweij, Daniëlle Horst, Bryan D Griffin, Rutger D Luteijn, Andrew J Davison, Maaike E Ressing, Emmanuel J H J Wiertz

“…The strategies of TAP inhibition employed by viruses are very distinct and are likely to have been acquired independently during evolution. …”
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Characterizing the services provided by family physicians in Ontario, Canada: A retrospective study using administrative billing data. by David W Savage, Arunim Garg, Salimur Choudhury, Roger Strasser, Robert Ohle, Vijay Mago

“…We investigated the services provided by family physicians in Ontario, Canada using a provincial physician database and administrative physician billing data from 2017. Billing codes were used to define 18 general services that family physicians may provide. …”
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Fractures and Chronic Recurrence are Commonly Associated with Ankle Sprains: a 5-year Population-level Cohort of Patients Seen in the U.S. Military Health System by Daniel I Rhon, Tina A Greenlee, Chad E Cook, Richard B Westrick, Jon A Umlauf, John J Fraser

“…Diagnosis and procedural codes were used to identify and categorize ankle sprains as isolated lateral, isolated medial, concomitant medial/lateral, unspecified, or concomitant ankle sprain with a malleolar or fibular fracture. …”
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Bridging the theory and practice divide in pre-service language teacher education: A focus on teacher educators’ expertise from in-service teachers' vantage point by George E.K. Whitehead, Sezen Arslan

“…Data were collected through in-depth semi-structured interviews and were thematically coded using NVivo 14 software. Participants commonly mentioned that language teacher educators in South Korea often lack current classroom experience, leading to an emphasis on outdated theories irrelevant to contemporary teaching needs. …”
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Applications of Trichoderma formulations in crop protection by Monte E, Rodriguez A, Rey M, Azpilicueta A, Gómez M I, de la Vin a G, Grondona I, Llobelt A

“…However, many other active strains have no antibiotic capacity, and these are likely to be more useful in food production systems since they have not adverse effects on important groups of beneficial soil organisms. …”
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Evaluation of a learning collaborative on team-based care: qualitative analysis of coaching calls using normalisation process theory by Kathleen Thies, Amanda Schiessl, Nashwa Khalid, Kasey Harding, Deborah Ward, Meaghan Angers

“…Similarly, the concurrence of cognitive participation and collective action likely refined each other. It took 3–4 months for most teams to establish sufficient coherence and cognitive participation, and to access actionable data. …”
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Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication. by Michael M Magwire, Florian Bayer, Claire L Webster, Chuan Cao, Francis M Jiggins

“…In a panel of inbred fly lines, we found that a transposable element insertion in the protein coding sequence of CHKov1 is associated with increased resistance to infection. …”
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An assessment of non-communicable disease mortality among adults in Eastern Uganda, 2010-2016. by Davis Natukwatsa, Adaeze C Wosu, Donald Bruce Ndyomugyenyi, Musa Waibi, Dan Kajungu

“…Information on cause of death was obtained through verbal autopsies using a structured questionnaire to conduct face-face interviews with carers or close relatives of the deceased. Physicians assigned likely cause of death using ICD-10 codes. Age-adjusted mortality rates were calculated using direct method, with the average population across the seven years of the study (2010 to 2016) as the standard. …”
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Progression of Heart Failure in People with Type 2 Diabetes in Germany: An Analysis Using German Health Insurance Claims Data by Keni Cheng-Siang Lee, Tobias Wagner, Adee Kennedy, Michael Wilke

“…A high number of patients may likely not survive a 5-year period. Validation of the model with German data is highly desirable. …”
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Accuracy of routinely-collected healthcare data for identifying motor neurone disease cases: A systematic review. by Sophie Horrocks, Tim Wilkinson, Christian Schnier, Amanda Ly, Rebecca Woodfield, Kristiina Rannikmäe, Terence J Quinn, Cathie L M Sudlow

“…<h4>Conclusions</h4>Diagnostic accuracy of routinely-collected health datasets is likely to be sufficient for identifying cases of MND in large-scale prospective epidemiological studies in high income country settings. …”
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A mixed methods exploration of the origin of dental anxiety and coping strategies among participants in a behavioral intervention for dental anxiety by Elizabeth Konneker, Devon Singh, Marisol Tellez, Amid I. Ismail, Eugene M. Dunne

“…Qualitative data were coded in NVivo.ResultsThe three identified origins for dental anxiety were: “traumatic dental visit in childhood,” “traumatic dental visit in adulthood,” and “anxiety has always been present.” …”
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Case report: Identification of a Chinese patient with RAG1 mutations initially presenting as autoimmune hemolytic anemia by Xin Chen, Chunxue Jiang, Wenliang Song, Tingting Sun, Jingli Yan, Wei Xu, Kai You

“…Whole exome and Sanger sequencing revealed a pathogenic recombinase-activating gene 1 mutation (c.2095C&gt;T, p.Arg699Trp) and a likely pathogenic variant (c.2690G&gt;A, p.Arg897Gln), resulting in a missense mutation in the amino acid sequence of the coding protein. …”
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Lower the Flag: A Qualitative Analysis of Behavioral Alerts in the Electronic Health Record by Zoë Kopp, Irina Kryzhanovskaya, Maria E. Garcia

“…Themes were generated through open and axial coding of BAs’ free-text and thematic analysis to describe the content of BAs. …”
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Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus. by Marie P Fogarty, Maren E Cannon, Swarooparani Vadlamudi, Kyle J Gaulton, Karen L Mohlke

“…Many of the type 2 diabetes loci identified through genome-wide association studies localize to non-protein-coding intronic and intergenic regions and likely contain variants that regulate gene transcription. …”
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One step on the QI journey: team perspectives on surveys for improvement by Julie E Reed, Julie K Johnson, Marjorie M Godfrey, Cassandra B Iroz

“…Data were analysed through multiple rounds of coding and inductive thematic analysis.Results Collaborative participants viewed surveys positively as an improvement tool. …”
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Interpersonal relationships in patients suffering from chronic musculoskeletal pain: a case-control study analyzing core conflictual relationship themes and interpersonal problems by Pernilla Abrahamsson, Bo Vinnars, Annika Lindgren

“…Controlling for these variables, components of CCRT were significantly more likely to be disharmonious in patients with CMP compared to patients with OA. …”
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What percentage of secondary school students do their homework with the help of artificial intelligence? - A survey of attitudes towards artificial intelligence by Mátyás Turós, Róbert Nagy, Zoltán Szűts

“…Although women have more positive attitudes toward using AI for learning purposes, they are less likely to use it to complete their homework assignments. …”
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ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry. by Anne-Laure Renault, Fabienne Lesueur, Yan Coulombe, Stéphane Gobeil, Penny Soucy, Yosr Hamdi, Sylvie Desjardins, Florence Le Calvez-Kelm, Maxime Vallée, Catherine Voegele, Breast Cancer Family Registry, John L Hopper, Irene L Andrulis, Melissa C Southey, Esther M John, Jean-Yves Masson, Sean V Tavtigian, Jacques Simard

“…To determine if ABRAXAS could be a breast cancer susceptibility gene in other populations, we conducted a population-based case-control mutation screening study of the coding exons and exon/intron boundaries of ABRAXAS in the Breast Cancer Family Registry. …”
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