Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models by E. T. Spangenberg, A. Moneypenny, G. G. Bozzo, M. L. Perreault

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Feasibility of Smartphone-Based Exercise Training Integrated with Functional Electrical Stimulation After Stroke (SETS): A Preliminary Study by Rudri Purohit, Juan Pablo Appelgren-Gonzalez, Gonzalo Varas-Diaz, Shuaijie Wang, Matias Hosiasson, Felipe Covarrubias-Escudero, Tanvi Bhatt

“…Secondary measures included motivation, acceptability and attitude, usability, and clinical measures of gait and balance function like the 10-Meter Walk Test and Mini-BESTest. …”
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Impact of sleep quality on disease progression in early-stage amyotrophic lateral sclerosis by Gan Zhang, Gan Zhang, Gan Zhang, Yong Chen, Yong Chen, Yong Chen, Lu Tang, Lu Tang, Lu Tang, Linna Bai, Hui Zhang, Hong Liu, Dongsheng Fan, Dongsheng Fan, Dongsheng Fan

“…Non-motor symptoms are clinical manifestations of amyotrophic lateral sclerosis (ALS). …”
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Specifications and functional impact of a self-triggered grasp neuroprosthesis developed to restore prehension in hemiparetic post-stroke subjects by R. Le Guillou, J. Froger, M. Morin, M. Couderc, C. Cormier, C. Azevedo-Coste, D. Gasq

“…Abstract Background Stroke is the leading cause of acquired motor deficiencies in adults. Restoring prehension abilities is challenging for individuals who have not recovered active hand opening capacities after their rehabilitation. …”
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Identification and functional analysis of a novel TBC1D23 pathogenic variant in a Chinese family with pontocerebellar hypoplasia by Kangyu Liu, Yu Chen, Yunlong Meng, Xinyao Wang, Xingkun Tang, Haining Li, Jianjun Chen, Zilin Zhong

“…We propose the severe phenotype stems from a primary loss-of-function (LoF), which is likely exacerbated by the cytotoxic effect of the truncated protein produced via partial NMD escape. …”
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Meta-Analysis of the Relationship between Deep Brain Stimulation in Patients with Parkinson’s Disease and Performance in Evaluation Tests for Executive Brain Functions by A. M. Martínez-Martínez, O. M. Aguilar, C. A. Acevedo-Triana

“…Parkinson’s disease (PD) is a neurodegenerative condition, which compromises the motor functions and causes the alteration of some executive brain functions. …”
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Automated extraction of functional biomarkers of verbal and ambulatory ability from multi-institutional clinical notes using large language models by Levi Kaster, Ethan Hillis, Inez Y. Oh, Bhooma R. Aravamuthan, Virginia C. Lanzotti, Casey R. Vickstrom, Brain Gene Registry Consortium, Christina A. Gurnett, Philip R. O. Payne, Aditi Gupta

“…Results LLM pipelines demonstrated high accuracy (weighted-F1 scores > .90) in predicting ambulatory ability for both cohorts, likely due to the consistent use of Gross Motor Functional Classification System (GMFCS) as a consistent ground-truth standard. …”
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Modeling Dual-Task Performance: Identifying Key Predictors Using Artificial Neural Networks by Arash Mohammadzadeh Gonabadi, Farahnaz Fallahtafti, Judith Heselton, Sara A. Myers, Ka-Chun Siu, Julie Blaskewicz Boron

“…Dual-task paradigms that combine cognitive and motor tasks offer a valuable lens for detecting subtle impairments in cognitive and physical functioning, especially in older adults. …”
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MicroRNA governs bistable cell differentiation and lineage segregation via a noncanonical feedback by Chung‐Jung Li, Ee Shan Liau, Yi‐Han Lee, Yang‐Zhe Huang, Ziyi Liu, Andrew Willems, Victoria Garside, Edwina McGlinn, Jun‐An Chen, Tian Hong

“…Using the developing spinal cord as a paradigm, we found that canonical, transcription‐driven feedback cannot explain robust lineage segregation of motor neuron subtypes marked by two cardinal factors, Hoxa5 and Hoxc8. …”
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Time-domain brain: temporal mechanisms for brain functions using time-delay nets, holographic processes, radio communications, and emergent oscillatory sequences by Janet M. Baker, Peter Cariani

“…A temporal theory for realizing major brain functions (e.g., sensation, cognition, motivation, attention, memory, learning, and motor action) is proposed that uses temporal codes, time-domain neural networks, correlation-based binding processes and signal dynamics. …”
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Brain Shaped by Music Performance: Cognitive Effects and Genetic Approaches by Emel Güneş, Şayeste Çağıl İnal

“…Cognitive functions such as verbal memory, motor functions, visual and spatial functions, executive functions are some of the cognitive components which are improved with music performance. …”
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Carpal tunnel release surgery restores force control but not force coordination in CTS patients by Thomas Jacob, Mohamed Ibrahim, G. Vishnu Babu, K. Shyamnath Krishna Pandian, R. Krishnamoorthy, G. Karthikeyan, P. Jeyakumar, V. S. Valarmathy, Jahir Hussain, C. S. Ezhilavan, K. Sridhar, Sivakumar Balasubramanian, S. K. M. Varadhan

“…Compression neuropathies like carpal tunnel syndrome (CTS) can have detrimental effects on hand function, which can be improved by surgical intervention. …”
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Detection of mild cognitive impairment using a virtual reality-based stroop task: a cross-sectional study of embodied behavioral markers by Jin-Hyuck Park

“…Importantly, baseline motor abilities did not significantly differ between groups, suggesting that executive function could contributed to performance differences. …”
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IMPAIRMENT OF HERP E3 LIGASE ACTIVITY BY MUTANT POLYGLUTAMINE PROTEINS: A NOVEL MECHANISM IN POLYGLUTAMINE DISEASE NEUROPATHOLOGY

“…Additionally, the ubiquitin-like (UBL) domain of Herp independently inhibits the aggregation of various polyglutamine (polyQ) proteins, suggesting its broad-spectrum anti-polyQ toxicity function. …”
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Connectome-based disentangling of epilepsy networks from insular stereoelectroencephalographic leads by Kathrin Machetanz, Eliane Weinbrenner, Thomas Volkmar Wuttke, Silke Ethofer, Randolph Helfrich, Josua Kegele, Stephan Lauxmann, Michael Alber, Sabine Rona, Marcos Tatagiba, Holger Lerche, Jürgen Honegger, Georgios Naros

“…Normative connectomes on MRI data enable to link different symptoms and lesion locations to a common functional network. The present study applied connectomics to disentangle epilepsy networks from insular SEEG recordings and to describe their relationship to seizure semiology.MethodsWe retrospectively extracted functional networks by normative connectome analysis from 118 insular contacts depicting epileptic discharges during SEEG in 20 epilepsy patients. …”
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Fabrication of a novel “all in one glove”- a functional tool for oral hygiene maintenance and the assessment of its effectiveness on plaque control in spastic cerebral palsy patien... by Sucharitha Palanisamy, Priyanka Cholan, Harinath Parthasarathy, Anupama Tadepalli

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Fine-Tuning of PI3K/AKT Signalling by the Tumour Suppressor PTEN Is Required for Maintenance of Flight Muscle Function and Mitochondrial Integrity in Ageing Adult Drosophila melano... by Lawrence B Mensah, Claire Davison, Shih-Jung Fan, John F Morris, Deborah C I Goberdhan, Clive Wilson

“…They also exhibit dramatic upregulation of the oxidative stress response gene, GstD1, and a progressive loss of motor function that ultimately leads to defects in climbing and flight ability. …”
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A molecular conveyor belt-associated protein controls the rotational direction of the bacterial type 9 secretion system by Abhishek Trivedi, Jacob A. Miratsky, Emma C. Henderson, Abhishek Singharoy, Abhishek Shrivastava

“…ABSTRACT Many bacteria utilize the type 9 secretion system (T9SS) for gliding motility, surface colonization, and pathogenesis. This dual-function motor supports both gliding motility and protein secretion, where rotation of the T9SS plays a central role. …”
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Transport and Kinetic Property of the Butyric Acid in Water: A Simulation Study by Priya Dey, Vishal Singh, Hemant Kumar

“…Studies suggest that the gut dysbiosis may enhance neurotoxic substances such as short-chain fatty-acids (SCFAs which are acetate, propionate, and butyrate) to the blood circulation and even to the brain through damaged blood brain barrier (BBB) and may cause protein aggregation which are implicated in the pathogenesis of several neurodegenerative diseases like Alzheimer’s disease (AD), Parkinson’s disease (PD), prion disease, motor neuron disease, Huntington’s disease (HD), Amyotrophic lateral sclerosis (ALS). …”
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Stingers—A Review of Current Understanding and Management by Teleale F. Gebeyehu, James S. Harrop, Joshua A. Dian, Stavros Matsoukas, Alexander R. Vaccaro

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