Para-median Forehead Flap for Nasal Reconstruction by Mohammed J. Alfeehan

“…Nasal reconstruction aims to gain a normal esthetic appearance and nasal function. Although para-median forehead flap achieves these two goals in the majority of patients, it carries some functional problems like nasal obstruction, crustation,  dryness of the nose, snoring, epistaxis, smell and voice abnormalities in the minority of them. …”
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RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation by Chiu-Lun Shen, Yu-Young Tsai, Shen-Ju Chou, Yao-Ming Chang, Woan-Yuh Tarn

“…Abstract Brain-derived neurotrophic factor (BDNF) plays important roles in brain development and neural function. Constitutive knockout of the splicing regulator RBM4 reduces BDNF expression in the developing brain and causes cerebellar hypoplasia, an autism-like feature. …”
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Choice-induced inter-trial inhibition is modulated by idiosyncratic choice-consistency. by Christian Wolf, Alexander C Schütz

“…These findings suggest that the suppression of alternative action plans is not coupled to target selection and motor execution but instead depends on top-down signals like the overall preference of one target over another.…”
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Multimodal closed-loop strategies for gait recovery after spinal cord injury and stroke via the integration of robotics and neuromodulation by Valeria de Seta, Valeria de Seta, Simone Romeni, Simone Romeni

“…By leveraging residual motor functions and integrating multimodal data from the different domains involved in motor recovery (i.e., brain, muscle, and biomechanics), the complementarity of these interventional strategies has the potential to enable dynamic patient-specific interventions. …”
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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors by Brianne Dentel, Lidiette Angeles-Perez, Abigail Y. Flores, Katherine Lei, Chongyu Ren, Andrea Pineda Sanchez, Peter T. Tsai

“…Previous studies have found seizure phenotypes and increased activity resulting from conditional deletion of GATOR1 function from forebrain excitatory neurons (Yuskaitis et al., 2018; Dentel et al., 2022); however, studies focused on understanding mechanisms contributing to NDD-relevant behaviors are lacking, especially studies understanding the contributions of GATOR1's critical GAP catalytic subunit, nitrogen permease regulator like-2 (Nprl2). …”
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Phase II open label study of valproic acid in spinal muscular atrophy. by Kathryn J Swoboda, Charles B Scott, Sandra P Reyna, Thomas W Prior, Bernard LaSalle, Susan L Sorenson, Janine Wood, Gyula Acsadi, Thomas O Crawford, John T Kissel, Kristin J Krosschell, Guy D'Anjou, Mark B Bromberg, Mary K Schroth, Gary M Chan, Bakri Elsheikh, Louise R Simard

“…Exploratory outcome measures included assessment of gross motor function via the modified Hammersmith Functional Motor Scale (MHFMS), electrophysiologic measures of innervation including maximum ulnar compound muscle action potential (CMAP) amplitudes and motor unit number estimation (MUNE), body composition and bone density via dual-energy X-ray absorptiometry (DEXA), and quantitative blood SMN mRNA levels. …”
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Studying turn performance, trunk control, and mobility in acute stroke subjects: a cross-sectional study by Mahima Vasyani, Akshatha Nayak, K. Vijaya Kumar, Zulkifli Misri, Pema Choezom, Rinita Mascarenhas, Jaya Shanker Tedla, Srikant Natarajan

“…Background Stroke leads to various impairments like motor deficits, impaired trunk control and restricted mobility. …”
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MALDI-TOF mass spectrometric protein profiling of THP-1 cells and their microvesicles by A. V. Korenevsky, Yu. P. Milyutina, M. E. Berezkina, E. P. Alexandrova, O. A. Balabas, K. L. Markova, S. A. Selkov, D. I. Sokolov

“…Pro-inflammatory cytokines produced by monocytes and individual complement system components play a key role in their specific functioning. The aim of this work was to study proteomic composition of THP-1 monocyte-like cells and their microvesicles. …”
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Ccdc80-l1 Is involved in axon pathfinding of zebrafish motoneurons. by Chiara Brusegan, Anna Pistocchi, Andrea Frassine, Isabella Della Noce, Filippo Schepis, Franco Cotelli

“…In particular, motoneurons extend their axons toward skeletal muscles, leading to spontaneous motor activity. In this study, we identified the zebrafish Ccdc80 and Ccdc80-like1 (Ccdc80-l1) proteins in silico on the basis of their high aminoacidic sequence identity with the human CCDC80 (Coiled-Coil Domain Containing 80). …”
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Assessment of neurobehavioral and histopathological impacts of graphene quantum Dots in NMRI mice by Farangiz Sourani, Hossein Najafzadehvarzi, Mohammad Ranaee, Atena Rahimi

“…The results from behavioral tests, as well as histological and biochemical evaluations, demonstrated that low doses of GQDs significantly impaired memory function and increased anxiety. High doses of GQDs notably reduced motor activity. …”
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Effect of Duration of Exposure of Thumb Movements While Operating Mobile Phone on Nerve Conduction Velocity and Handgrip Strength in Undergraduate Medical Students by Jagdish C. Hundekari, Sanjay Wasnik, Manoj Paliwal, Indrajeet Yadav, Chandeep Kau, Bhumika Badjatiya, Lokendra Kot, Ranjana Sharma

“…Students these days are continuously engaged in their mobile phones chatting with each other or probably playing games like PubG. Aims and Objective: In the present study, we investigated the handgrip strength and median motor nerve conduction velocity to assess the impact of duration of mobile usage on the functional status of the hands. …”
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Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury by Sarah Mantash, Soulaimane Aboulouard, Hassan Dakik, Yanis Zirem, Lydia Ziane-Chaouche, Ali Nehme, Khalil Mallah, Marya El-Kurdi, Naify Ramadan, Isabelle Fournier, Kazem Zibara, Firas Kobeissy, Michel Salzet

“…Key deregulated proteins, including Apoa1, ApoE, Cox6a1, and Snca, were linked to neurodegenerative pathways, suggesting molecular connections between TBI and diseases like AD and PD. Behavioral assessments indicated that repetitive TBI significantly impaired motor and cognitive functions, with recovery in motor function by day 30, whereas cognitive deficits persisted. …”
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Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype. by Daniela Kuzdas-Wood, Regina Irschick, Markus Theurl, Philipp Malsch, Norbert Mair, Christine Mantinger, Julia Wanschitz, Lars Klimaschewski, Werner Poewe, Nadia Stefanova, Gregor K Wenning

“…In a transgenic MSA mouse model featuring GCI-like inclusion pathology based on PLP-promoter driven overexpression of human α-syn in oligodendroglia motor and non-motor deficits are associated with MSA-like neurodegeneration. …”
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Cucurbita maxima Seeds Reduce Anxiety and Depression and Improve Memory by Shahana Wahid, Ali Alqahtani, Rafeeq Alam Khan

“…Four central nervous system-related functions, that is, anxiety, depression, memory, and motor coordination, were evaluated, and the levels of brain biogenic amines were also assessed. …”
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Adults with down syndrome exhibit altered somatosensory cortical inhibition by Jiraros Meejang, Morgan T. Busboom, Sarah E. Baker, Yasra Arif, Olyvia Kastner, Tony W. Wilson, Max J. Kurz

“…Down syndrome (DS) is a developmental genetic disorder that is associated with an accelerated aging profile and high probability of early incidence Alzheimer’s disease like symptoms. It is well established that there are morphological differences in the brains of adults with DS, but the net impact of the genetic disruption on cortical function remains poorly understood. …”
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Developing a Serious Video Game to Engage the Upper Limb Post-Stroke Rehabilitation by Jaime A. Silva, Manuel F. Silva, Hélder P. Oliveira, Cláudia D. Rocha

“…Stroke often leads to severe motor impairment, especially in the upper limbs, greatly reducing a patient’s ability to perform daily tasks. …”
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Rett Syndrome: From Bed to Bench by Shih-Ming Weng, Mark E.S. Bailey, Stuart R. Cobb

“…Clinical diagnosis has been based on symptoms such as loss of acquired purposeful hand skills, autistic behaviors, motor dysfunctions, seizure disorders, and gait abnormalities. …”
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Evaluating the Impact of Early Intervention on Developmental Outcomes in Children with Autism Spectrum Disorder: A Comparative Study in Bangladesh by Anika Ferdous, MD Nahid Hassan Nishan, Siva Ganesan

“…Tailored EI programs addressing these areas could enhance developmental outcomes and functional independence for children with ASD in resource-limited settings like Bangladesh. …”
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Modeling schizophrenia endophenotypes in drosophila melanogaster: effects of ketamine on anxiety, aggression, locomotion and inflammatory responses by Abdulrahman Adesola Bello, Royhaan Olamide Folarin

“…</div><div>The results showed a dose-dependent induction of aggressive behavior. Motor function assays demonstrated that ketamine impaired these functions in a dose-dependent manner. …”
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5-HT2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study by Nadja Bredo Rasmussen, Mikkel Vestergaard Olesen, Tomasz Brudek, Per Plenge, Anders Bue Klein, Jenny E. Westin, Karina Fog, Gitta Wörtwein, Susana Aznar

“…The 5-HT2A receptor is highly involved in aspects of cognition and executive function and seen to be affected in neurodegenerative diseases like Alzheimer’s disease and related to the disease pathology. …”
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