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181
Coexisting Disorders and Problems in Preschool Children with Autism Spectrum Disorders
Published 2013-01-01“…Information on autistic symptoms, general cognitive function, speech and language, motor function, epilepsy, vision, hearing, activity level, behavior, and sleep was collected. …”
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182
The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson’s disease with diabetes co-morbidity
Published 2025-06-01“…ObjectiveTo investigate the effects of the glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide on motor function, necroptosis, and neuroinflammation in the brain in mice with diabetic Parkinson’s disease (PD) and its possible mechanism.MethodsWe prepared a diabetic model with streptozotocin, followed by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced diabetic PD model, along with liraglutide or saline intervention, and the control group with equal volume saline. …”
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183
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility
Published 2024-12-01“…However, in the current study we show that loss of NSG2 had highly selective effects on associative learning and memory, leaving motor and affective behaviors intact. For instance, NSG2 KO animals performed equivalent to wild-type C57Bl/6n mice on rotarod and Catwalk motor tasks, and did not display alterations in anxiety-like behavior on open field and elevated zero maze tasks. …”
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184
Neonatal febrile seizures: Dimethyl itaconate's role in behavioral recovery and glutathione enzyme modulation in adult rats.
Published 2025-01-01“…Febrile seizures are common in children and can lead to neurological deficits like motor impairments, memory problems, and cognitive decline. …”
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185
CircPRDM5-mediated regulation of miR-433-3p and HDAC6 in Parkinson's disease: a novel neuroprotective axis
Published 2025-05-01“…Behavioral tests, histological analysis, and immunohistochemistry were used to evaluate motor function and neuronal integrity. In vitro, SH-SY5Y neuroblastoma cells were treated with MPP⁺ to induce PD-like characteristics, followed by transfection with circPRDM5 knockdown constructs and miR-433-3p mimics or inhibitors. …”
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186
Exploring the Impact of Stroke on Lower Limb Proprioception: Insights into Physiotherapy Interventions for Rehabilitation: Systematic Review
Published 2025-03-01“…Emerging therapies, including telerehabilitation and neurostimulation, highlight the potential for innovative approaches in stroke rehabilitation and functional recovery. Conclusion: This review highlights that targeted physical therapy interventions, such as sensory re-education and balance training, significantly improve stroke survivors' proprioception, balance, and motor function, promoting better functional recovery. …”
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187
Exploring the role of neuromodulation in neurodegenerative disorders: Insights from Alzheimer's and Parkinson's diseases
Published 2025-03-01“…TMS showed significant improvement in cognitive functions in AD patients, while DBS resulted in substantial relief of motor symptoms and improved quality of life in PD patients. …”
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188
SMA Community Priorities for Future Drug Therapies: Cross-Sectional Survey Findings Representing 410 Adults with SMA
Published 2025-05-01“…Gaining muscle strength was the most frequently reported unmet need, and followed by improving daily functioning, achieving new motor function, and stabilizing motor function. …”
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189
The Transcription of Transposable Elements Differentially Regulated by SVAs in the Major Histocompatibility Complex Class I Region of a Parkinson’s Progression Markers Initiative C...
Published 2025-01-01“…The SVA-regulated TE RNAs in blood cells appear to function as enhancer-like elements, differentially influencing the expression of HLA class I genes, non-HLA genes, and noncoding RNAs. …”
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190
Parkinson’s disease detection using inceptionV3: A Deep learning approach
Published 2025-06-01“…Parkinson's disease (PD) is a neurodegenerative condition that progressively affects motor function and causes tremors, rigidity, and bradykinesia. …”
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191
Mutation of Mitochondrial DNA G13513A Presenting with Leigh Syndrome, Wolff-Parkinson-White Syndrome and Cardiomyopathy
Published 2008-08-01“…Supplementation with coenzyme Q10, thiamine and carnitine prevented further regression in gross motor function but the patient's heart function deteriorated and dilated cardiomyopathy developed 11 months later. …”
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192
ELAVL1-mediated USP29 mRNA degradation activates TAK1 driving M1 microglial polarization and neural stem cell differentiation dysregulation in spinal cord injury
Published 2025-07-01“…A rat model of SCI was established via spinal cord transection at the tenth thoracic vertebra segment, followed by short hairpin RNA (shRNA) lentivirus infection. Motor function and coordination were evaluated while histopathological analysis of spinal cord tissues was conducted. …”
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194
Artificial transneurons emulate neuronal activity in different areas of brain cortex
Published 2025-08-01“…We compare activity of these artificial neurons with the spiking activity of biological neurons measured in sensory, pre-motor, and motor cortical areas of the monkey (male) brain. …”
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195
Neuroprotective effects of Kapikachhu (Mucuna pruriens) in a paraquat-induced zebrafish model of neurotoxicity relevant to Parkinson's disease
Published 2025-06-01“…Behavioural assessments, including novel tank, light–dark, and mirror-induced aggression tests, demonstrated that Kapikachhu-treated zebrafish exhibited reduced anxiety-like behaviours and improved motor function compared to untreated PQ-exposed zebrafish. …”
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196
A Pilot Study on Mixed-Reality Approaches for Detecting Upper-Limb Dysfunction in Multiple Sclerosis: Insights on Cerebellar Tremor
Published 2025-01-01“…The assessment and rehabilitation of upper-limb functionality are crucial for addressing motor disorders in individuals with multiple sclerosis (PwMS). …”
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197
Coding and non-coding RNA expression in NSC34 cells following TDP-43 depletion and mutant TDP-43 M337V expression
Published 2025-07-01“…Therefore, RNA changes induced by TDP-43 depletion or mutation could play an important role in the pathogenesis of ALS and other TDP-43 related NDDs.To investigate these effects in NSC34 motor neuron-like cells, a commonly used cellular model of ALS, we used RNA interference to knock down TDP-43 and overexpressed the ALS-associated TDP-43 M337V mutation. …”
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198
Atypical Presentation of Atraumatic Spinal Subdural Hematoma Associated with Warfarin: A Case Report and Review of the Literature
Published 2019-01-01“…At the 2-week mark, the patient was still incontinent and showed 2/2 sensory and 2/5 motor functions in select muscle groups in her bilateral lower extremities. …”
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199
State-Space Method-Based Frame Dynamics Analysis of the Six-Rotor Unmanned Aerial Vehicles
Published 2025-06-01“…These vibrations, often generated by motor-propeller systems or aerodynamic forces, can lead to structural fatigue during flight or cause image blur in payloads like cameras. …”
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200
Efficacy of suspension exercise training in spinal cord injury: a systematic review and meta-analysis
Published 2025-07-01“…Conclusion This study has demonstrated that SET is likely to improve motor and balance functions, as well as activities of daily living, in patients, while also contributing to a reduction in muscle tone. …”
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