Characterising Eye Movement Events With an Unsupervised Hidden Markov Model by Malte Lüken, Šimon Kucharský, Ingmar Visser

“…Comparingthem indicated that HMMs with more events than expected had most likely generated thedata. We also applied the full algorithm to benchmark data and assessed its similarity tohuman coding. …”
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The organization of semantic associations between senses in language by Jorge A. Alvarado, Carlos Velasco, Alejandro Salgado

“…Community detection techniques were applied to unveil domains of experience where crossmodal correspondences were likely to manifest, while also considering the role of affective dimensions in shaping these domains. …”
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Separable roles for RNAi in regulation of transposable elements and viability in the fission yeast Schizosaccharomyces japonicus. by Elliott Chapman, Francesca Taglini, Elizabeth H Bayne

“…However, this species is somewhat atypical in that TEs are not major targets of RNAi, and instead small RNAs correspond primarily to non-coding pericentromeric repeat sequences, reflecting a specialised role for the pathway in promoting heterochromatin assembly in these regions. …”
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Mapping the Indian Palaeolithic by Vaneshree Vidyarthi, Parth Chauhan

“…This study also demonstrates that geocoded sites are not necessarily accurate, but rather indicate the most likely option. The distant structure (ie. top down) and application of GIS make it intrinsically divorced from local reality. …”
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“Trojan horse” malware as a mean for obtaining evidence in Italy by Francesco Caprioli

“…The Italian code of criminal procedure doesn’t regulate investigations realized with “Trojan horse” malwares located in an electronic device like a smartphone or a tablet. …”
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CARLA-GymDrive: Autonomous driving episode generation for the Carla simulator in a gym environmentGitHub by Ângelo Miguel Rodrigues Morgado, Nuno Gonçalo Coelho Costa Pombo

“…It includes features such as scenario configuration to ensure that the training/test suite is adequate without requiring any code. Additionally, it boasts other features such as custom sensor configuration and compatibility with training libraries like Stable-Baselines3. …”
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α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback by Ying-Hao Hu, Ying-Hao Hu, Jun Han, Jun Han, Lin Wang, Chao Shi, Chao Shi, Yan Li, Yan Li, Opeyemi Joshua Olatunji, Xiu Wang, Xiu Wang, Jian Zuo, Jian Zuo, Jian Zuo

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Phenotype and function of human monocytes remain mainly unaffected by very small superparamagnetic iron oxide particles by Sari Hussein, Sari Hussein, Anja Andrea Kühl, Laura Golusda, Laura Golusda, Christina Plattner, Nadine Heinze, Nadine Heinze, Gregor Sturm, Christian Freise, Heike Traub, Mathias Schannor, Zlatko Trajanoski, Matthias Taupitz, Britta Siegmund, Daniela Paclik, Daniela Paclik

“…RNA sequencing of monocytes identified the transferrin receptor as one of the most significantly downregulated genes after VSOP treatment, likely to limit iron uptake. Whereas whole blood RNA sequencing showed significant changes only in three non-coding genes. …”
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Mechanisms of drug resistance in hepatocellular carcinoma by Yongchun Zou, Xinliang Wan, Qichun Zhou, Gangxing Zhu, Shanshan Lin, Qing Tang, Xiaobing Yang, Sumei Wang

“…Although novel therapies like lenvatinib, sorafenib, regorafenib, and ICIs have shown promise, their effectiveness is often hindered by primary and acquired resistance, leading to poor long-term survival outcomes. …”
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Identification of miRNAs associated with Aspergillus flavus infection and their targets in groundnut (Arachis hypogaea L.) by Pushpesh Joshi, Vinay Sharma, Arun K. Pandey, Spurthi N. Nayak, Prasad Bajaj, Hari K. Sudini, Shailendra Sharma, Rajeev K. Varshney, Manish K. Pandey

“…Although the transcriptomic control is not fully understood, the interaction between long non-coding RNAs and microRNAs in regulating A. flavus and aflatoxin contamination remains unclear. …”
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Health Catch-UP!: a realist evaluation of an innovative multi-disease screening and vaccination tool in UK primary care for at-risk migrant patients by Jessica Carter, Lucy P. Goldsmith, Felicity Knights, Anna Deal, Subash Jayakumar, Alison F. Crawshaw, Farah Seedat, Nathaniel Aspray, Dominik Zenner, Philippa Harris, Yusuf Ciftci, Fatima Wurie, Azeem Majeed, Tess Harris, Philippa Matthews, Rebecca Hall, Ana Requena-Mendez, Sally Hargreaves

“…Conclusions Clinical Decision Support Systems like Health Catch-UP! can improve disease detection and implementation of screening guidance for migrant patients but require robust testing, resourcing, and an effective implementation package to support both patients and staff.…”
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Development of Multiplex Assays for the Identification of Zoonotic <i>Babesia</i> Species by Ana Cláudia Calchi, Charlotte O. Moore, Lillianne Bartone, Emily Kingston, Marcos Rogério André, Edward B. Breitschwerdt, Ricardo G. Maggi

“…In contrast, because the <i>Babesia</i> internal transcribed regions (ITS), between 18S rRNA and 5.8S rRNA, and between 5.8S rRNA and 28S rRNA, contain highly variable non-coding regions, the sequences in these regions provide a good option for developing molecular assays that facilitate differentiation at the species level. …”
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A novel anxiety-associated SNP identified in LYNX2 (LYPD1) is associated with decreased protein binding to nicotinic acetylcholine receptors by Kristin R. Anderson, Wenpeng Cao, Hui Sun Lee, Mark A. Crenshaw, Talulla B. Palumbo, Ethan Fisher-Perez, Amanda DeGraaf, Peter Rogu, Maria A. Beatty, Gabrielle M. Gracias, Gabrielle M. Gracias, Avani V. Pisapati, Katie Hoffman, Krystle J. McLaughlin, Almut Hupbach, Wonpil Im, Wonpil Im, X. Frank Zhang, Julie M. Miwa

“…The murine Lynx2 gene, encoding a protein modulator of nicotinic acetylcholine receptors, is expressed in anxiety-related neural circuitry in rodents and has been functionally associated with anxiety-like behavior.MethodsWe examined variations in the human LYNX2 (LYPD1) gene and their potential effects on anxiety levels in a cohort of 624 participants. …”
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miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages by Carmen Alexandra Neculachi, Evelyn-Gabriela Nastase-Rusu, Laudy Cherry, Catalina Iolanda Marinescu-Colan, Spyros Tastsoglou, Bogdan Paul Cosman, Alina Madalina Popa, Cristina Panciuc, Germana Zaccagnini, Germana Zaccagnini, Sergiu Bogdan Catrina, Sergiu Bogdan Catrina, Maya Simionescu, Fabio Martelli, Fabio Martelli, Mihai Bogdan Preda, Alexandrina Burlacu

“…MiR-210 is a hypoxia-inducible, small non-coding RNA involved in regulating metabolic adaptation and inflammatory responses during normal repair processes. …”
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An Analytical Solution for Variable Viscosity Flow in Fractured Media: Development and Comparative Analysis With Numerical Simulations by Anis Younes, Mohammad Mahdi Rajabi, Fatemeh Rezaiezadeh Roukerd, Marwan Fahs

“…This assumption, however, can be inaccurate as fluid viscosity varies due to factors like composition, temperature, and dissolved substances. …”
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Deep CNN-based detection of cardiac rhythm disorders using PPG signals from wearable devices. by Miray Gunay Bulut, Sencer Unal, Mohamed Hammad, Paweł Pławiak

“…Arrhythmias can disrupt the balanced circulation, leading to serious complications like heart attacks, strokes, and sudden death. Medical devices like electrocardiography (ECG) and Holter monitors are commonly used for diagnosing and monitoring cardiac rhythm disorders. …”
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Chromosome-level haplotype-resolved genome of the tropical loach (Oreonectes platycephalus) by Xi Wang, Dandan Wang, Hongbo Wang, David Dudgeon, Kerry Reid, Juha Merilä

“…Chr01 was identified as the likely sex chromosome pair. After masking repetitive elements which accounted for 34.43% to 36.44% of the genome, there are 27,127 protein-coding genes in haplotype A and 25,576 in haplotype B. …”
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Mechanistic insights into the therapeutic effects on liver fibrosis in Wilson's disease: a transcriptomic and network pharmacology-based approach by Ying Ma, Yue Pu, Hong Chen, Lei Zhou, Bo Yang, Xiaofeng Huang, Juan Zhang

“…Main signaling pathways included IL-17, HIF-1, prolactin, and NF-κB.ConclusionThe therapeutic effects of BSHXHZF in liver fibrosis associated with WD are likely linked to its modulation of sphingolipid and IL-17 signaling pathways.…”
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Design and pre-clinical evaluation of a universal HIV-1 vaccine. by Sven Létourneau, Eung-Jun Im, Tumelo Mashishi, Choechoe Brereton, Anne Bridgeman, Hongbing Yang, Lucy Dorrell, Tao Dong, Bette Korber, Andrew J McMichael, Tomás Hanke

“…<h4>Significance</h4>Therefore, this vaccine approach provides an attractive and testable alternative for overcoming the HIV-1 variability, while focusing T cell responses on regions of the virus that are less likely to mutate and escape. Furthermore, this approach has merit in the simplicity of design and delivery, requiring only a single immunogen to provide extensive coverage of global HIV-1 population diversity.…”
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Preschool Teachers’ Perceptions of the Potential of Giftedness by Özlem Çerezci, H. Elif Dağlıoğlu

“…The statements were analysed and coded separately by the researchers at least three times while categorizing the data, and the codes and categories were finalised after three experts’ views.Findings: Preschool teachers were found to be most likely to take into account the cognitive developmental characteristics of these children both before and after receiving the education. …”
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