Study on the mechanisms and functions of lncRNAs in regulating carboplatin resistance in ovarian cancer cells by HONG Yi, CHEN Cuilan, YIN Fuqiang, LIU Xia

“…Objective To screen for differentially expressed long non-coding RNAs (lncRNAs) in carboplatinresistant ovarian cancer (OC) based on expression profiling microarrays and conduct functional enrichment analysis to comprehensively understand the signaling pathways of lncRNAs in response to carboplatin resistance in OC. …”
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Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences by Muhammad Ali, Pierre Garcia, Laetitia P. Lunkes, Alessia Sciortino, Melanie H. Thomas, Tony Heurtaux, Kamil Grzyb, Rashi Halder, Alexander Skupin, Luc Buée, David Blum, Manuel Buttini, Enrico Glaab

“…Multiple genes with established implications in AD, including the long non-coding RNA gene Malat1, displayed concordant sex-specific changes in mouse models and human AD. …”
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Digital Storytelling and Students’ Academic Engagement in Civic Education: Implications for Sustainable Development by Celestine Nkanu, David Francis Ekpoto, Amina Peter Adams, Idorenyin Edet Johnson, Anthony Etta Bisong, Odim Otu Offem, Efut Etim Nkanu, Fredrick Awhen Opoh, Samuel Manyo Takon, Agnes Edet Asuquo Offiong, James Eburikure Olayi, Samuel Orim Orim, Flora Michael Monity, James Abua Ewa, Oyobo-Gladys Tom Abam, John Edogi Egbe, Akaninyene Billy Orok, Joseph Enyia Ekpang

“…Applying an instructional delivery strategy that is both effective and innovative in teaching a very important subject like Civic Education will no doubt contribute greatly to the attainment of quality education for all. …”
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GenomicGapID: leveraging spatial distribution of conserved genomic sites for broad-spectrum microbial identification by Vishwaratn Asthana, Pallavi Bugga, Clara Elaine Smith, Catherine Wellman, Zachary Dwight, Piyush Ranjan, Erika Martínez Nieves, Robert P. Dickson, J. Scott VanEpps

“…Traditional untargeted methods, such as culture and sequencing, are often time-consuming and expensive, while targeted techniques like PCR offer speed and cost-effectiveness but require pre-selection of pathogens. …”
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Cuproptosis: a novel therapeutic mechanism in lung cancer by Cheng Luo, Xinhui Wu, Shipeng Zhang, Junwen Tan, Yuzhi Huo, Xinyue Zhang, Bo Ning, Yuanhang Ye, Fei Wang

“…Additionally, the abnormal expression of crucial regulatory genes, such as FDX1 and LIPT1, along with transport proteins like CTR1 and ATP7A/B, is closely linked to the advancement of lung cancer. …”
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Unveiling racial disparities in prostate cancer using an integrative genomic and transcriptomic analysis by Abdalla Elbialy, Akshay Sood, Shang-Jui Wang, Peng Wang, Ahmed Fadiel, Anil V. Parwani, Steven Huang, Gennady Shvets, Nagireddy Putluri, Jenny Li, Xuefeng Liu

“…Additionally, pseudogenes and long non-coding RNAs (lncRNAs) among the regulated genes indicate non-coding elements' role in these disparities.Exome sequencing identified unique variants in AA patient samples within key genes, including TP73 (tumor suppression), XYLB (metabolism), ALDH4A1 (oxidative stress), PTPRB (cellular signaling), and HLA-DRB5 (immune response). …”
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Qualitative Content Analysis of Isfahan Telegram Channels by Ahmad Mehrshad, ali rabbani-khorasgani, abdolhosein kalantari, Mohammad mahdi Zolfaghar zadeh

“…Purposeful sampling was done among 18 channels of Isfahan-based shared posts based on defined criteria and finally coding was done on 135 posts. According to the results of the research, five main categories are visible in posts liked by Isfahan users, namely "tendency for criticismtendency to know" and "Isfahan's Identity" is described below with examples of each of the categories and sub-categories.…”
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Do infants use cues of saliva-sharing to infer close relationships? A replication of Thomas et al. (2022) by Beyza Gokcen Ciftci, Jonathan Frank Kominsky, Gergely Csibra

“…Our study sought to replicate their crucial experiment (2B), which was conducted online and reported that 8.5- to 10-month-old infants anticipated that a crying individual would be more likely to be comforted by a person who had been observed to share saliva with her than another person who simply had played with her. …”
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A Complexity Reduction Method for Intra Prediction Method in HEVC Standard by Zahra Mirian, Mohammadreza Ramezanpour

“…High Efficiency Video Coding (HEVC) is considered the last standard for video compression with about 50% additional compression compared to the previous standard i.e. …”
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Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum. by Marna S Costanzo, Kyle M Brown, Daniel L Hartl

“…However, a handful of mutations in the gene coding for one such enzyme, dihydrofolate reductase, confer drug resistance. …”
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Nonsignificance misinterpreted as an effect’s absence in psychology: prevalence and temporal analyses by Stephen Lee Murphy, Raphael Merz, Linda-Elisabeth Reimann, Aurelio Fernández

“…Our models indicate that between 76% and 85% of psychology articles published between 2009 and 2021 that discussed a nonsignificant finding misinterpreted nonsignificance as reflecting no effect. It is likely between 54% and 62% of articles over this time period claimed explicitly that this meant no effect on the population of interest. …”
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ENHANCING EXPLAINABILITY IN DEEPFAKE DETECTION WITH GRAPH ATTENTION NETWORKS by Aleksandr S. Pikul, Ilya Yu. Popov

“…Many current methods, like Shapley additive explanations (SHAP) and Gradient-weighted Class Activation Mapping (Grad-CAM), help explain these decisions, but they often aren't detailed enough for tasks involving complex data like human faces. …”
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Reading, Writing and the “Straight White Male”: What Masculinity Studies Does to Literary Analysis by Pierre-Antoine Pellerin

“…Combined with the textual and performative approach developed by queer theorists, the work done by historians of masculinity enables, for instance, to shed light on the pressures that burdened authorial identity in a context of homophobia like the Cold War period in the United States, to delineate the ways in which the constitutive homosociality of poetic circles in the 1950s fashioned their aesthetic norms and practices, and to deconstruct the narrative codes and the fictions of masculinity which structured certain literary genres like the crime novel and the adventure novel.…”
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A phenomenological study of knowledge concealment in country water and sewage engineering company by Gholamreza Moghadasi, Hamidreza Rezaei Kelidbari, Mohammad Doostar

“…The data analysis method is based on coding and categorization. Data analysis was done using MAXQDA 2020 software. …”
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Fibre tracing in biomedical images: An objective comparison between seven algorithms. by Youssef Arafat, Cristina Cuesta-Apausa, Esther Castellano, Constantino Carlos Reyes-Aldasoro

“…In biomedical applications, the analysis of traces of vasculature, nerves or fibres of the extracellular matrix can help characterise processes like angiogenesis or the effect of a certain treatment. …”
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Mutations in mitochondrial DNA causing tubulointerstitial kidney disease. by Thomas M Connor, Simon Hoer, Andrew Mallett, Daniel P Gale, Aurora Gomez-Duran, Viktor Posse, Robin Antrobus, Pablo Moreno, Marco Sciacovelli, Christian Frezza, Jennifer Duff, Neil S Sheerin, John A Sayer, Margaret Ashcroft, Michael S Wiesener, Gavin Hudson, Claes M Gustafsson, Patrick F Chinnery, Patrick H Maxwell

“…Thus mutations in mitochondrial DNA can cause maternally inherited renal disease, likely mediated through reduced function of mitochondrial tRNAPhe.…”
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Multisystem Resilience in Disaster Volunteers: A Review of the Literature by Yuli Arinta Dewi, Koentjoro Soeparno, Pradytia Putri Pertiwi, Mizan Bustanul Fuady

“…Findings indicate that, compared to other forms of civic engagement, disaster volunteering is more likely to involve physical and mental health risks. …”
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Etiologic Characteristics of Influenza Epidemics on the Territory of Russia in the Period of Pandemic COVID-­19 in 2020–2023 by P. A. Petrova, N. I. Konovalova, A. Y. Boyarintseva, D. M. Danilenko, A. D. Vasilieva, T. N. Shelepanova, A. V. Prokopets, M. Y. Eropkin

“…All studied influenza B viruses belonged to the Victoria lineage and were B/Austria/1359417/2021-like. According to the phylogenetic analysis, all modern Victoria strains clustered into the sub-clade V1A.3a.2, coding the substitutions A127T, P144L и K203R in HA1. …”
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Humorous peer play and social understanding in childhood by Amy Louise Paine, Salim Hashmi, Elian Fink, Peter Mitchell, Nina Howe

“…Abstract Humour plays a crucial role in children’s early interactions, likely promoting the development of social understanding and fostering positive social relationships. …”
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Shared regulatory sites are abundant in the human genome and shed light on genome evolution and disease pleiotropy. by Pin Tong, Jack Monahan, James G D Prendergast

“…This study shows that regulatory site-sharing is likely an underappreciated aspect of gene regulation and has important implications for the understanding of various biological phenomena, including how the two and three dimensional structures of the genome have been shaped and the potential causes of disease pleiotropy outside coding regions.…”
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