Systematic assessment of COVID-19 host genetics using whole genome sequencing data. by Axel Schmidt, Nicolas Casadei, Fabian Brand, German Demidov, Elaheh Vojgani, Ayda Abolhassani, Rana Aldisi, Guillaume Butler-Laporte, DeCOI host genetics group, T Madhusankha Alawathurage, Max Augustin, Robert Bals, Carla Bellinghausen, Marc Moritz Berger, Michael Bitzer, Christian Bode, Jannik Boos, Thorsten Brenner, Oliver A Cornely, Thomas Eggermann, Johanna Erber, Torsten Feldt, Christian Fuchsberger, Julien Gagneur, Siri Göpel, Tobias Haack, Helene Häberle, Frank Hanses, Julia Heggemann, Ute Hehr, Johannes C Hellmuth, Christian Herr, Anke Hinney, Per Hoffmann, Thomas Illig, Björn-Erik Ole Jensen, Verena Keitel, Sarah Kim-Hellmuth, Philipp Koehler, Ingo Kurth, Anna-Lisa Lanz, Eicke Latz, Clara Lehmann, Tom Luedde, Carlo Maj, Michael Mian, Abigail Miller, Maximilian Muenchhoff, Isabell Pink, Ulrike Protzer, Hana Rohn, Jan Rybniker, Federica Scaggiante, Anna Schaffeldt, Clemens Scherer, Maximilian Schieck, Susanne V Schmidt, Philipp Schommers, Christoph D Spinner, Maria J G T Vehreschild, Thirumalaisamy P Velavan, Sonja Volland, Sibylle Wilfling, Christof Winter, J Brent Richards, DeCOI, André Heimbach, Kerstin Becker, Stephan Ossowski, Joachim L Schultze, Peter Nürnberg, Markus M Nöthen, Susanne Motameny, Michael Nothnagel, Olaf Riess, Eva C Schulte, Kerstin U Ludwig

“…Burden testing in the largest population subgroup (i.e., Europeans) suggested nominal enrichments of rare variants in coding and non-coding regions of interferon immune response genes in the overall analysis and male subgroup. …”
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Implementation of Machine Learning Applications in Health Care Organizations: Systematic Review of Empirical Studies by Luigi M Preti, Vittoria Ardito, Amelia Compagni, Francesco Petracca, Giulia Cappellaro

“…The implementation process was investigated using a thematic analysis and coding procedure. ResultsThirty-four studies were selected for data synthesis. …”
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Bioinformatics‑Based Analysis Reveals Diagnostic Biomarkers and Immune Landscape in Atopic Dermatitis by Yang M, Zhang X, Zhou C, Du Y, Zhou M, Zhang W

“…KEGG analysis showed significant involvement of sphingolipid metabolism and Toll-like receptor signaling pathways. Five hub genes (ATP6V1A, CLDN23, ECSIT, LRFN5, USP16) were identified. …”
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Leveraging the dynamic adaptation process to address LGBTQ+ health equity in New Mexico high schools by Cathleen Elizabeth Willging, Cathleen Elizabeth Willging, Daniel Shattuck, Daniel Shattuck, Mary M. Ramos, Mary M. Ramos, Bonnie O. Richard, Adrien Lawyer, Elizabeth Dickson, Gregory A. Aarons

“…It also fostered relationship-building and leadership, encouraging school leaders to legitimate implementation efforts and champion health equity for LGBTQ+ students.DiscussionParticipatory implementation science models like the DAP can help prioritize health equity for marginalized populations by enabling the uptake of practices likely to contribute to well-being. …”
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Reconfigurable optoelectronic neuromorphic properties of MoS2-based memristors decorated with Pt nanoparticles for low power spiking neural network applications by Chrysi Panagopoulou, Panagiotis Bousoulas, Georgia Iliani Papouli, Maria Kainourgiaki, Charalampos Tsioustas, Maria Karnachoriti, Athanassios G Kontos, Dimitris Tsoukalas

“…More specifically, the reference samples without Pt NPs exhibited only synaptic behavior, while the NPs-based one (surface density of ∼2 × 10 ^12 NPs cm ^−2 ) presented a neuron-like response. An elevated surface density (∼5 × 10 ^12 NPs cm ^−2 ) just reduced the frequency of the generated spikes. …”
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Impact of Surgeon Specialty on Ankle Arthrodesis Readmission, Complication, and Infection Rates: A Medicare Analysis by Devon Nixon MD, Hyunkyu Ko PhD, Brook Martin PhD

“…The implication of findings like these will require further study to better understand how foot and ankle care is administered to patients at a policy-level.…”
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Inherited disorders of neonatal lung diseases by Murat Yurdakök

“…The most promising candidates are the genes coding for the lung-specific protein components of the surfactant. …”
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Positive Selection of TLR2 and MyD88 Genes Provides Insights Into the Molecular Basis of Immunological Adaptation in Amphibians by Jie Zhang, Ruinan Zhao, Hongyan Bi, Jiaoying He, Yang Guo, Dian Liu, Ganggang Yang, Xiaohong Chen, Zhuo Chen

“…Here, we determined the coding regions, expression patterns of TLR2 and Myeloid differentiation factor 88 (MyD88) in the large treefrog (Zhangixalus dennysi), and explored the evolutionary patterns of these two genes in amphibians. …”
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Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress by Haoqi Liu, Zhiyuan Yin, Mengping Qiu, Yan Yang, Ye Xu, Han Wang, Min Yan, Guohua Xu

“…Abstract Background The CCT (CONSTANS, CONSTANS-LIKE and TOC1) gene family plays a crucial role in regulating diurnal rhythms and responding to abiotic stress, which significantly impacts crop growth, development, and yield. …”
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A novel lncRNA YIL163C enhances genomic stability and antifungal resistance via the DNA damage response in Saccharomyces cerevisiae by Xueting Wang, Xueting Wang, Xuemei Li, Duoyun Li, Yiying Zhang, Bing Bai, Bao Chai, Zewen Wen

“…IntroductionLong non-coding RNAs (lncRNAs) are increasingly recognized as key regulators in cellular processes, including the DNA damage response (DDR). …”
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Deep learning-based computational approach for predicting ncRNAs-disease associations in metaplastic breast cancer diagnosis by Saleem Ahmad, Imran Zafar, Shaista Shafiq, Laila Sehar, Hafsa Khalil, Nida Matloob, Mehvish Hina, Sidra Tul Muntaha, Hamid Khan, Najeeb Ullah Khan, Samreen Rana, Ahsanullah Unar, Muhammad Azmat, Muhammad Shafiq, Yousef A. Bin Jardan, Musaab Dauelbait, Mohammed Bourhia

“…Abstract Non-coding RNAs (ncRNAs) play a crucial role in breast cancer progression, necessitating advanced computational approaches for precise disease classification. …”
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The Ways of Using Social Media for Health Promotion Among Adolescents: Qualitative Interview and Focus Group Study by Elizabeth Zimmermann, Samuel Tomczyk

“…Furthermore, most adolescents did not like notifications and switched them off. …”
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Kinetics of pIgR and IgM immune responses in snakehead (Channa argus) to inactivated Aeromonas hydrophila via immersion and intraperitoneal injection by Guojing Xu, Lili Cao, Xiuli Chen, Fangfang Guo, Yan Jiang, Xiangyue Li, Haiqiang Xu, Jinliang Zang, Junpeng Wang, Yuguang Qin

“…The ChpIgR had a pair of immunoglobulin-like domains in addition to a transmembrane region and an intracellular region. …”
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Comparative chloroplast genomics of wild-type Panicum miliaceum cv. ATL1 and its M4 mutant line: insights for molecular breeding applications by Ayushi Kumar, Ravikesavan Rajasekaran, Iyanar Krishnamoorthy, Senthil Alagarswamy, K. Chandrakumar, Sowmya Pulapet, Kesavan Markkandan, Selvaraju Kanagarajan, Manikanda Boopathi Narayanan

“…The identification of protein-coding genes regulating photosynthesis components (photosystems I and II, NADH dehydrogenase, cytochrome complexes, rubisco, and ribosomal/tRNA/rRNA genes) in both investigated cp. genomes provides critical insights into the genomic basis of photosynthesis efficiency in underutilized C4 crops like proso millet, a key trait for improving stress-resilient sustainable agriculture. …”
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The telomere-to-telomere gap-free genome assembly of Juglans sigillata by Delu Ning, Tao Wu, Wenlong Lei, Shengcheng Zhang, Ting Ma, Li Pan, Liangjun Xiao, Noor-ul- Ain, Xingtan Zhang, Fuliang Cao

“…The comprehensive genome assembly and the understanding of the genetic basis of important traits like endopleura coloration will open avenues for more efficient breeding programs and improved crop quality.…”
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LncRNA MEG3 exacerbates diabetic cardiomyopathy via activating pyroptosis signaling pathway by Shengnan Zhuo, Yifeng Liu, Siyuan Wang, Zhuoling Chen, Xuran Shi, Yangjunna Zhang, Dengfeng Xu, Jingjin Hu, Yin Wang, Xuefeng Qu

“…Background: Diabetic cardiomyopathy (DCM) is a prevalent complication observed in diabetic patients. The long non-coding RNA maternally expressed gene 3 (lncMEG3) has been found to be intricately associated with myocardial infarction and heart failure. …”
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Roles of circRNAs in viral pathogenesis by Jiayin Liu, Jiayin Liu, Yiming Wang, Yiming Wang, Meichun Zheng, Meichun Zheng, Jiayuan Du, Jiayuan Du, Mohamed Maarouf, Mohamed Maarouf, Ji-Long Chen, Ji-Long Chen

“…Circular RNAs (circRNAs) are a class of non-coding RNAs with a covalently closed circular structure, lacking 5’-caps or 3’-poly(A) tails. …”
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Host genetic factors and vaccine-induced immunity to hepatitis B virus infection. by Branwen J Hennig, Katherine Fielding, John Broxholme, Mathurin Diatta, Maimuna Mendy, Catrin Moore, Andrew J Pollard, Pura Rayco-Solon, Giorgio Sirugo, Marianne A van der Sande, Pauline Waight, Hilton C Whittle, Syed M Zaman, Adrian V Hill, Andrew J Hall

“…Odds of core-conversion was associated with variation in CD163. A coding change in ITGAL (R719V) with likely functional relevance showed evidence of association with increased peak anti-HBs level in both screens (1st screen: s595_22 GMTratio 1.71, P = 0.013; 2nd screen: s595_22 GMTratio 2.15, P = 0.011).…”
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A facile photonics reconfigurable memristor with dynamically allocated neurons and synapses functions by Zhenyu Zhou, Lulu Wang, Gongjie Liu, Yuchen Li, Zhiyuan Guan, Zixuan Zhang, Pengfei Li, Yifei Pei, Jianhui Zhao, Jiameng Sun, Yahong Wang, Yiduo Shao, Xiaobing Yan

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MARIA (Medical Assistance and Rehabilitation Intelligent Agent) for Medication Adherence in Patients With Heart Failure: Empirical Results From a Wizard of Oz Systematic Conversati... by Nik Nailah Abdullah, Jia Tang, Hemad Fetrati, Nor Fadhilah Binti Kaukiah, Sahrin Bin Saharudin, Vee Sim Yong, Chia How Yen

“…Dialogue data collected through WoZ simulations were analyzed using a coding analysis technique. ResultsOur design method for the CA revealed gaps in MARIA’s conception, including (1) handling negative responses, (2) appropriate use of emoticons to enhance human-likeness, (3) system feedback mechanisms during turn-taking delays, and (4) defining the extent to which a CA can communicate on behalf of a health care provider regarding medication adherence. …”
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