Experimental swap of Anopheles gambiae's assortative mating preferences demonstrates key role of X-chromosome divergence island in incipient sympatric speciation. by Fred Aboagye-Antwi, Nahla Alhafez, Gareth D Weedall, Jessica Brothwood, Sharanjit Kandola, Doug Paton, Abrahamane Fofana, Lisa Olohan, Mauro Pazmiño Betancourth, Nkiru E Ekechukwu, Rowida Baeshen, Sékou F Traorè, Abdoulaye Diabate, Frédéric Tripet

“…Furthermore, full-genome sequencing confirmed that protein-coding differences between recombinant strains were limited to the experimentally swapped pericentromeric region. …”
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Epithelial-mesenchymal transition in colorectal cancer metastasis and progression: molecular mechanisms and therapeutic strategies by Fangfang Nie, Xue Sun, Jizhuo Sun, Jingdong Zhang, Yuanhe Wang

“…Beyond metastasis, EMT facilitates cancer cells’ adaptation to diverse microenvironments, gain of stem cell-like characteristics, metabolic reprogramming, and evasion of therapeutic interventions. …”
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P21 Ablation Unveils Strain-Specific Transcriptional Reprogramming in Trypanosoma cruzi Amastigotes by Anna Clara Azevedo Silveira, Iara Dantas de Souza, João Vitor Ferreira Cavalcante, Thaise Lara Teixeira, Cristina Mary Orikaza, Rodrigo Juliani Siqueira Dalmolin, José Franco da Silveira, Claudio Vieira da Silva

“…P21 is encoded by a single-copy, nonconserved gene expressed across all T. cruzi life cycle stages. Its sequence codes for a protein implicated in cell invasion and parasite multiplication. …”
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Evolutionary conservation of salinity responsive miRNAs from Indian wheat (Triticum aestivum) landrace, Kharchia Local by MAHENDRA C, KUMAR NUPUR HRISHIKESHAN, AHMED MOHAMMED ISMAIL, PRADEEP KUMAR JAIN, KISHOR GAIKWAD, KANIKA KUMAR

“…These regulations are carried out by many regulatory molecules including microRNAs and transcription factors. Like protein coding genes, miRNAs are also conserved across the plant species to exhibit their conserved function during growth, development and response to biotic or abiotic stresses. …”
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Ecolodge Success Model: Antecedents and Consequences by Zohreh Dehdashti Shahrokh, Mohammadreza Karimi Alavijeh, Molood Esfahani

“…Using Seven-step method of Sandelowski and Barroso, the findings of 55 previous studies related to the research objectives were reviewed, aggregated, combined and interpreted. Using the coding method, the number of 100 codes, 24 themes and 8 dimensions were identified and the validity of the coding was confirmed through the Cohen's kappa test, and the success model of the ecolodge: antecedents and consequences was presented and drawn. …”
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Early presentation of spastic paraparesis in individuals carrying PSEN1 mutations: a clinical and genetic analysis by Kang-Yang Jih, Ting-Rong Hsu, Jong-Ling Fuh, Tse-Hao Lee, Yung-Shuan Lin, Shih-Yu Fang, Yi-Chu Liao, Yi-Chung Lee

“…This study aims to investigate the clinical and genetic features of PSEN1 variants in patients mainly manifested with hereditary spastic paraparesis (HSP)-like phenotypes. Methods Mutational analysis was performed in 242 unrelated Taiwanese patients with clinically suspected HSP using a targeted resequencing panel covering the entire coding regions of PSEN1, along with 76 genes associated with HSP and 55 genes linked to HSP-like phenotypes. …”
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Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110 by Laura Schlüter, Kine Østnes Hansen, Johan Isaksson, Jeanette Hammer Andersen, Espen Holst Hansen, Jörn Kalinowski, Jörn Kalinowski, Yannik Karl-Heinz Schneider

“…SE50/110 has high industrial relevance. Like most Actinobacteria, the strain carries several more putative biosynthetic gene clusters (BGCs) to produce further natural products, which are to be discovered. …”
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Biophysical characterization of TREM2 missense variants implicated in neurodegenerative disease by Joshua Pillai, Kijung Sung, Linda Shi, Chengbiao Wu

“…Outside of known variants in the IgV-like domain, we identified 10 variants that imposed significant destabilizing effects to the structure and are of potential interest. …”
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Nuclear paraspeckle assembly transcript 1 promotes photophobia behavior in mice via miR-196a-5p/Trpm3 coupling by Zhuoan Huang, Xingshen Li, Xiaolin Wang, Jiaqi Wu, Ziyang Gong, Sulev Kõks, Minyan Wang

“…Similar to knocking down NEAT1, TRPM3 inhibition reduced photophobia-like behavior. Conclusion We conclude that NEAT1 is critical for promoting photophobia behavior via miR-196a-5p/Trpm3 coupling.…”
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Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states. by Shaoyi Ji, Ze Yang, Leonardi Gozali, Thomas Kenney, Arif Kocabas, Carolyn Jinsook Park, Mary Hynes

“…As with other long non-coding (lncRNAs), isolated 3'UTRs are likely to play an important role in gene regulation, but little is known about the contexts in which they are deployed. …”
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Hidden origami in Trypanosoma cruzi nuclei highlights its non-random 3D genomic organization by Natália Karla Bellini, Pedro Leonardo Carvalho de Lima, David da Silva Pires, Julia Pinheiro Chagas da Cunha

“…ABSTRACT The protozoan Trypanosoma cruzi is the causative agent of Chagas disease and is known for its polycistronic transcription, with about 50% of its genome consisting of repetitive sequences, including coding (primarily multigenic families) and non-coding regions (such as ribosomal DNA, spliced leader [SL], and retroelements, etc). …”
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SUMBER DAYA RESILIENSI PEMILIK USAHA DALAM MENGHADAPI PANDEMI COVID-19 by Cicilia Larasati Rembulan, Kuncoro Dewi Rahmawati, Prisca Eunike, Tasia Puspa Sari

“…Besides, external resources like strategic business partners and family members had also an important contribution to their resilience. …”
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Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs by Stefano Capomaccio, Katia Cappelli, Cinzia Bazzucchi, Mauro Coletti, Rodolfo Gialletti, Franco Moriconi, Fabrizio Passamonti, Marco Pepe, Stefano Petrini, Samanta Mecocci, Maurizio Silvestrelli, Luisa Pascucci

“…Gene Ontology analysis showed enrichment for terms like “extracellular exosome,” “organelle envelope,” “RNA binding,” and “small molecule metabolic process.” …”
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Systematic method for developing tailored strategies for implementing point-of-care procalcitonin testing to guide antibiotic prescribing in Swiss primary care: a protocol for a mi... by Lauren Clack, Joachim Marti, Byron J Powell, Yolanda Mueller, Noémie Boillat-Blanco, Anna Nicolet, Rahel Naef, Aline Wolfensberger, Sophie CL Gendolla, Jelena Dunaiceva, Catherine Plüss-Suard, Anne Niquille

“…Point-of-care (POC) tests for inflammatory biomarkers like procalcitonin (PCT) have shown promise in reducing unnecessary antibiotic prescriptions. …”
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Effectiveness of interventions for improving educational outcomes for people with disabilities in low‐ and middle‐income countries: A systematic review by Xanthe Hunt, Ashrita Saran, Howard White, Hannah Kuper

“…These inequalities in education contribute to people with disabilities being less likely to achieve employment, or earn as much if they are employed, as people without disabilities. …”
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Evaluation of the Impact of Public Space Design on Enhancing Psychological Resilience of Citizens after Urban Crises (Case Study: Oskou urban) by Faegheh Zirdabi Oskouei, MirSaead Moosavi, Nasim Najafgholipour Kalantari, Akbar Abdollahzadeh Taraf

“…In conclusion, the findings suggest that designing public spaces with a focus on biophilic elements and environmental psychology can substantially enhance the psychological resilience of citizens, offering valuable insights for urban planning in smaller cities like Oskou.…”
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Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease. by Katja Derkow, Rosa Rössling, Carola Schipke, Christina Krüger, Jakob Bauer, Michael Fähling, Andrea Stroux, Eckart Schott, Klemens Ruprecht, Oliver Peters, Seija Lehnardt

“…MicroRNAs (miRNAs) are non-coding RNAs originally involved in RNA silencing and post-transcriptional regulation of gene expression. …”
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Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq. by Mandy Jayne Peffers, Katarzyna Goljanek-Whysall, John Collins, Yongxiang Fang, Michael Rushton, John Loughlin, Carole Proctor, Peter David Clegg

“…Epigenetic mechanisms, like DNA methylation, contribute to the changes in gene expression in ageing. …”
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Association Analysis and Identification of Candidate Genes for Sorghum Coleoptile Color by Kai Wang, Lihua Wang, Qi Shen, Lu Hu, Zhichao Xing, Yihong Wang, Jieqin Li

“…Coleoptile is a sheath-like structure unique to monocots and is easily observed in sorghum. …”
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Subject Advisors’ Understanding of their Curriculum Leadership Roles for Mathematics Improvement in South African Schools by Thabo France Sithole, Simon Adjei Tachie, Tafirenyika Mafugu

“…They also handled administrative tasks findings like resource provision and paperwork using monitoring tools. …”
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