Alum-anchored IL-12 combined with cytotoxic chemotherapy and immune checkpoint blockade enhanced antitumor immune responses in head and neck cancer models by James W Hodge, Howard Kaufman, Michelle R Padget, Kellsye P Fabian, Sailaja Battula, Wiem Lassoued, Ginette Santiago-Sanchez, Clint Tanner Allen

“…For MOC1, flow cytometry and cytokine array were performed to assess the immune effector functions associated with the combinational treatment. …”
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<i>C11orf58</i> (Hero20) Gene Polymorphism: Contribution to Ischemic Stroke Risk and Interactions with Other Heat-Resistant Obscure Chaperones by Irina Shilenok, Ksenia Kobzeva, Vladislav Soldatov, Alexey Deykin, Olga Bushueva

“…<b>Background</b>: Recently identified Hero proteins, which possess chaperone-like functions, are promising candidates for research into atherosclerosis-related diseases, including ischemic stroke (IS). …”
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Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism by Wesley H Godfrey, Judy J Lee, Shruthi Shanmukha, Kaho Cho, Xiaojing Deng, Chandra Shekar R Ambati, Vasanta Putluri, Abu Hena Mostafa Kamal, Paul M Kim, Nagireddy Putluri, Michael D Kornberg

“…The differentiation and suppressive functions of regulatory CD4 T cells (Tregs) are supported by a broad array of metabolic changes, providing potential therapeutic targets for immune modulation. …”
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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistan... by Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi

“…Abstract Background The epidermal growth factor receptor (EGFR) plays a significant role in vasculogenic mimicry (VM), a process by which aggressive cancer cells within hypoxic solid tumors form blood vessel-like structures independent of endothelial cells. …”
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Role of Nonthermal Processes in the Quiescent and Active Millimeter Spectrum of a Young M Dwarf by Atul Mohan, Peter H. Hauschildt, Birgit Fuhrmeister, Surajit Mondal, Vladimir Airapetian, Sven Wedemeyer

“…We present the quiescent mm- S ( ν ) of a young dM, AD Leo, observed around 94 GHz using the Northern Extended Millimetre Array. The observed quiescent mm- S ( ν ) exceeds the thermal flux density from a 1D chromospheric model, constrained by optical-UV spectroscopic data, by up to a factor of 7. …”
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Advanced Braille recognition based on protein biomimetic skin mechanical sensors by Nianfeng Zhang, Ailing Yang, Andeng Liu, Guoxi Shao, Xixi Wang, Yingjin Luo, Zhihua Liu, Yating Shi, Na Li, Wenxi Guo, Wu Qiu, Dapeng Yang

“…The key to mimicking skin tactile perception is to address skin-like properties of materials and integration of biomimetic tactile functions. …”
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The Activation of the NF-κB Pathway in Human Adipose-Derived Stem Cells Alters the Deposition of Epigenetic Marks on H3K27 and Is Modulated by Fish Oil by Jussara de Jesus Simao, Andressa França de Sousa Bispo, Victor Tadeu Gonçalves Plata, Ana Beatriz Marques Abel, Raphael Justa Saran, Júlia Fernandes Barcella, João Carlos Cardoso Alonso, André Valente Santana, Lucia Maria Armelin-Correa, Maria Isabel Cardoso Alonso-Vale

“…Plasma lipopolysaccharide (LPS) activates Toll-like receptor 4 (TLR4), triggering NF-κB and worsening these disturbances. …”
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A versatile development platform for odor monitoring systems by M. Koehne, M. Koehne, O. T. Penagos Carrascal, O. T. Penagos Carrascal, M. Czerny, G. Zeh, T. Sauerwald, T. Sauerwald

“…For 10 and 100 times higher concentrations, hexanal (grassy) and octanal (citrus-like) could be detected. All three detectors were in parallel, and odor impressions could be assigned to mass spectrometer and sensor peaks. …”
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Interdisciplinary Insights and Global Perspectives on ADHD in Children: A Comprehensive Bibliometric Analysis (2014–2024) by Mohamed E. Elnageeb, Elsadig Mohamed Ahmed, Khalid M. Adam, Ali M. Edris, Elshazali Widaa Ali, Elmoiz Idris Eltieb, Eltayeb Abdelazeem Idress, D. S. Veerabhadra Swamy, Mohammed Hassan Moreljwab, Ali M. S. Eleragi

“…The Scopus database is utilized to gather a diverse array of scholarly research on this complex ailment. …”
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The performance of 76 kHz positional acoustic telemetry is challenged by acoustic conditions in the tailrace of a hydroelectric dam by C. Ryan Hill, Antóin M. O’Sullivan, R. Allen Curry, Tommi Linnansaari, Philip M. Harrison

“…The telemetry system is likely not suitable for studies that require frequent and reliable positions in hydropower dam tailrace environments.…”
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Sites of Planet Formation in Binary Systems. II. Double the Disks in DF Tau by Taylor Kutra, Lisa Prato, Benjamin M Tofflemire, Rachel Akeson, G. H. Schaefer, Shih-Yun Tang, Dominique Segura-Cox, Christopher M. Johns-Krull, Adam Kraus, Sean Andrews, Eric L. N. Jensen

“…This article presents the latest results of our Atacama Large Millimeter/submillimeter Array (ALMA) program to study circumstellar disk characteristics as a function of orbital and stellar properties in a sample of young binary star systems known to host at least one disk. …”
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Internal-wave-induced dissipation rates in the Weddell Sea Bottom Water gravity current by O. Pinner, F. Pollmann, M. Janout, G. Voet, T. Kanzow, T. Kanzow

“…The analysis is based on velocity records from a mooring array deployed across the continental slope between January 2017 and January 2019 as well as vertical profiles of temperature and salinity measured on various ship expeditions on a transect along the array. …”
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The Zymoseptoria tritici effector Zt-11 contributes to aggressiveness in wheat. by Sujit Jung Karki, Paola Pilo, Colleen Lawless, Nikolaos Mastrodimos, Anna M M Tiley, James Burke, Angela Feechan

“…Z. tritici secretes an array of effector proteins that are likely to facilitate host infection, colonisation and pycnidia production. …”
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Sol-gel synthesized CoFe2-xGdxO4:SiO2 nanocomposites for structural, thermal and magnetic investigation by Meenakshi Bansal, Dharamvir Singh Ahlawat, Amrik Singh, Shish Pal Rathee, Vijay Kumar, Anjali Maan, Mahipal Singh

“…Appearance of bands in FTIR spectra at 860.09 cm−1, 586.57 cm−1 and an array of 559–580 cm−1 are contributed by Si–O–Fe vibrations and absorption bands of Gd3+ respectively. …”
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Replication of European hypertension associations in a case-control study of 9,534 African Americans. by Harpreet Kaur, Dana C Crawford, Jingjing Liang, Penelope Benchek, COGENT BP Consortium, Xiaofeng Zhu, Asha R Kallianpur, William S Bush

“…In this study, we examined a large AA cohort for the generalizability of 14 Metabochip array SNPs with previously reported European hypertension associations.…”
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Bordetella adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages by Jawid Nazir Ahmad, Martin Modrak, Marketa Fajfrova, Blanca Martin-Borja Sotoca, Oldrich Benada, Peter Sebo

“…ABSTRACT Bordetella pertussis infects human upper airways and deploys an array of immunosuppressive virulence factors, among which the adenylate cyclase toxin (CyaA) plays a prominent role in disarming host phagocytes. …”
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Ultrathin and Highly Conformal Self-Powered Sensors by Liquid-Phase Transferring by Xingyi Dai, Qihua Liang, Yinghui Wu, Jiaxin Han, Yajun Cao, Xuyang Zhang, Junhui Huang, Junle Qu, Long-Biao Huang, Jie Kong, Jianhua Hao

“…Herein, we present an ultrathin self-powered sensor with high conformability, fabricated by a liquid-phase transferring approach. The sandwich-like sensor is spin-coated layer by layer on a water-soluble substrate. …”
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Abundant Molecular Gas in the Central Region of Lenticular Galaxy PGC 39535 by Jiantong Cui, Qiusheng Gu, Shiying Lu, Zhengyi Chen, Can Xu, Zeyu Gao

“…The results of the NOEMA observation suggest that the molecular gas mainly concentrates in the central regions as a gaseous bar and a ring-like structure, and shows similar kinematics as the stellar and ionized gas components. …”
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A specialized reference panel with structural variants integration for improving genotype imputation in Alzheimer disease and related dementias by Po-Liang Cheng, Hui Wang, Beth A. Dombroski, John J. Farrell, Iris Horng, Tingting Chung, Giuseppe Tosto, Brian W. Kunkle, William S. Bush, Badri Vardarajan, Gerard D. Schellenberg, Wan-Ping Lee

“…These findings provide the other insights into AD genetics and underscore the critical role of imputation panels in advancing our understanding of complex diseases like ADRD.…”
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High-Risk PNPLA3 rs738409 Genotype Is Associated with Higher Concentrations of CCL2 in Liver Transplant Candidates with Alcoholic End-Stage Liver Disease by Ivan Budimir Bekan, Dino Šisl, Alan Šućur, Ana Bainrauch, Valerija Bralić Lang, Pavao Planinić, Nataša Kovačić, Danka Grčević, Anna Mrzljak, Tomislav Kelava

“…<i>Background and Objectives</i>: Patients with GG rs738409 patatin-like phospholipase domain-containing protein 3 (PNPLA3) genotype (148M variant) have greater risk to develop end-stage liver disease and its associated clinical complications, including hepatocellular carcinoma (HCC). …”
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