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  1. 521

    Human platelet lysate enhances small lipid droplet accumulation of human MSCs through MAPK phosphorylation by Ping Du, Xuelian Tao, Javad Harati, Yue Shi, Liang Xiao, Xian Li, Haobo Pan, Peng-Yuan Wang

    Published 2024-12-01
    “…Gene and protein expression profiles of hPL-treated MSCs differed from those in adipocyte-like cells. An angiogenic factor array revealed that hPL-MSCs had a distinct angiogenic factor profile compared to FBS-MSCs, with VEGF expression closely linked to HIF-1α expression. …”
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  2. 522

    Research Trends in the Field of Participatory Governance: Drawing a Map of Co-occurrence and Co-word Analysis by Seyed Mohsen Mirbagheri, Seyed Mostafa Jalili

    Published 2023-12-01
    “…Experts in participatory governance face the daunting task of navigating through an extensive array of research documents to analyze the field's various strengths and weaknesses. …”
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  3. 523

    Comparative genomic insights into ecological adaptations and evolutionary dynamics of Trebouxiophyceae algae by Qian Xiong, Luqin Zheng, Qi Zhang, Tianli Li, Lingling Zheng, Lirong Song

    Published 2025-08-01
    “…Abstract Background The Trebouxiophyceae is a diverse and species-rich class within the Chlorophyta, exhibiting a wide array of lineages and remarkable variations in morphology and ecology. …”
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  4. 524
  5. 525

    Mon R2: A Hub–Filament System with an Infrared Bubble at the Hub Center by L. K. Dewangan, N. K. Bhadari, A. K. Maity, O. R. Jadhav, Saurabh Sharma, A. Haj Ismail

    Published 2025-01-01
    “…C ^18 O(1–0) emission detected by the Atacama Large Millimeter/submillimeter Array (ALMA) reveals several accreting filaments connected to a molecular ring (size ∼0.18 pc × 0.26 pc). …”
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  6. 526

    Acute myeloid leukemia-derived extracellular vesicles induced DNA methylation changes responsible for inflammatory program in normal hematopoietic stem progenitor cells by Daniela Lamorte, Giovanni Calice, Stefania Trino, Michele Santodirocco, Antonella Caivano, Luciana De Luca, Ilaria Laurenzana

    Published 2025-04-01
    “…These deGs were involved in NF-kB pathway, interleukin mediate Toll like receptor signaling and, of note, in tumor.ConclusionThis study is the first proof-of-concept that AML-EVs were able to induce changes in DNA methylation of HSPCs modulating the expression of genes involved in inflammatory processes capable of modifying normal hematopoiesis towards leukemic like processes.…”
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  7. 527

    SNP Microarray in FISH Negative Clinically Suspected 22q11.2 Microdeletion Syndrome by Ashutosh Halder, Manish Jain, Amanpreet Kaur Kalsi

    Published 2016-01-01
    “…SNP microarray was carried out using 300 K HumanCytoSNP-12 BeadChip array or CytoScan 750 K array. SNP microarray identified 8 cases of 22q11.2 microdeletions and/or microduplications in addition to cases of chromosomal abnormalities and other pathogenic/likely pathogenic CNVs. …”
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  8. 528

    Interplay between microtubule bundling and sorting factors ensures acentriolar spindle stability during C. elegans oocyte meiosis. by Timothy J Mullen, Sarah M Wignall

    Published 2017-09-01
    “…These proteins localize to the acentriolar oocyte spindle and promote microtubule bundling during spindle assembly; following KLP-15/16 depletion, microtubule bundles form but then collapse into a disorganized array. Surprisingly, despite this defect we found that during anaphase, microtubules are able to reorganize into a bundled array that facilitates chromosome segregation. …”
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  9. 529

    MinMax Optimization Algorithm for Reproducing All Tooth Shades Utilizing Vita Classical Colors by Osama Abu-Hammad, Jamal Rahhal, Raed Abulhasan, Rand Al-Smadi, Rasha Rahhal, Shaden Abu-Hammad, Sary Borzangy, Nebras Althagafi, Rawah Eshky, Najla Dar-Odeh

    Published 2025-04-01
    “…Conclusion: B1, B3, and C4 are the colors most likely to produce all other colors through direct mixing having the least AE.…”
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  10. 530

    A Novel Beam-Domain Direction-of-Arrival Tracking Algorithm for an Underwater Target by Xianghao Hou, Weisi Hua, Yuxuan Chen, Yixin Yang

    Published 2024-10-01
    “…Underwater direction-of-arrival (DOA) tracking using a hydrophone array is an important research subject in passive sonar signal processing. …”
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  11. 531

    Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways by Jiyi Xu, Ziyu Ge, Han Wang, Chenhui Zhang, Jinjie Xu, Ying Li, Xiangyun Yang, Ling Zhang, Zhanjiang Li, Zhe Liu, Gang Wang, Jing Du

    Published 2025-04-01
    “…After 14 days of administration, anxiety-like behaviors were assessed using elevated-plus maze and open-field tests. …”
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  12. 532

    Post-return stroke VHF electromagnetic activity in north-western Mediterranean cloud-to-ground lightning flashes by A. Kolínská, A. Kolínská, I. Kolmašová, I. Kolmašová, E. Defer, O. Santolík, O. Santolík, S. Pédeboy

    Published 2025-02-01
    “…<p>We investigate properties of the electromagnetic activity following the first lightning return stroke (RS), using concurrent observations from the SLAVIA (Shielded Loop Antenna with a Versatile Integrated Amplifier) sensor, the SAETTA (Suivi de l'Activité Electrique Tridimensionnelle Totale de l'Atmosphère) Lightning Mapping Array (LMA) and the METEORAGE LF (low-frequency) network in the Corsica region. …”
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  13. 533

    Comparative transcriptomic, epigenomic and immunological analyses identify drivers of disparity in high-grade serous ovarian cancer by Hao Huang, Russel Keathley, Ujin Kim, Horacio Cardenas, Ping Xie, Jianjun Wei, Ernst Lengyel, Kenneth P. Nephew, Guangyuan Zhao, Zhen Fu, Emma L. Barber, Masha Kocherginsky, Victoria Bae-Jump, Bin Zhang, Daniela Matei

    Published 2024-12-01
    “…HGSOC from 35 Black and 31 White patients were analyzed by Infinium Methyation-EPIC array and RNA sequencing. 191 CpG sites were differentially methylated (FDR < 0.05, β value change> 10%) and 277 genes were differentially expressed (FDR < 0.05). …”
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  14. 534

    Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients’ Upper and Lower Airways after IV-Antibiotic Therapy by Ulrike Müller, Julia Hentschel, Wibke K. Janhsen, Kerstin Hünniger, Uta-Christina Hipler, Jürgen Sonnemann, Wolfgang Pfister, Klas Böer, Thomas Lehmann, Jochen G. Mainz

    Published 2015-01-01
    “…In cystic fibrosis (CF) the upper (UAW) and lower airways (LAW) are reservoirs for pathogens like Pseudomonas aeruginosa. The consecutive hosts’ release of proteolytic enzymes contributes to inflammation and progressive pulmonary destruction. …”
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  15. 535

    Noninvasive prognostication of hepatocellular carcinoma based on cell-free DNA methylation. by Ran Hu, Benjamin Tran, Shuo Li, Mary L Stackpole, Weihua Zeng, Yonggang Zhou, Andrew Melehy, Saeed Sadeghi, Richard S Finn, Xianghong Jasmine Zhou, Wenyuan Li, Vatche G Agopian

    Published 2025-01-01
    “…<h4>Methods</h4>Using Illumina HumanMethylation450 array data of 377 HCC tumors and 50 adjacent normal tissues obtained from The Cancer Genome Atlas (TCGA), we identified 158 HCC-related DNA methylation markers associated with overall survival (OS). …”
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  16. 536

    Network Efficient Hierarchical Authentication Algorithm for Secure Communication in IoT and IoE by Abhiram Sharma, R. Suganya, P. B. Krishna, Rudra Raj, Raja Kumar Murugesan

    Published 2024-01-01
    “…However, adopting this also exposes significant vulnerabilities, as traditional authentication methods like AES and Triple-DES often incur high computational overhead and struggle to adapt to the diverse array of devices within IoT and IoE environments. …”
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  17. 537

    Genomic characterization of antimicrobial-resistant Salmonella enterica in chicken meat from wet markets in Metro Manila, Philippines by Michael Joseph M. Nagpala, Michael Joseph M. Nagpala, Jonah Feliza B. Mora, Rance Derrick N. Pavon, Windell L. Rivera

    Published 2025-02-01
    “…Phenotypic AMR testing revealed that 73.68% of the isolates were resistant to at least one drug class, and 45.26% were MDR. A wide array of antimicrobial resistance genes (ARGs) associated with resistance to 12 different drug classes was identified, including three β-lactamase gene variants: blaCTX-M-65, blaTEM-1, and blaTEM-176. …”
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  18. 538

    Exploring miRNA profile associated with cisplatin resistance in ovarian cancer cells by Yaman Alghamian, Chadi Soukkarieh, Abdulmunim Aljapawe, Hossam Murad

    Published 2025-03-01
    “…They may also target pathways involved in treatment response like PI3K-Akt, pathway in cancer and MAPK. Interestingly, High expression of hsa-miR-133b, hsa-miR-512-are, hsa-miR-200b-3p, and hsa-miR-451a is related to poor overall survival in patients diagnosed with ovarian cancer. …”
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  19. 539

    A Compact Triple Band EBG Using Interdigital Coplanar Waveguide Structure for Antenna Gain Enhancement by Prapoch Jirasakulporn, Pongsathorn Chomtong, Kamorn Bandudej, Prayoot Akkaraekthalin

    Published 2020-01-01
    “…The proposed EBG unit cell is based on a square mushroom-like EBG (M-EBG) structure with an interdigital coplanar waveguide (ICPW). …”
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  20. 540

    Dynamic Analysis and FPGA Implementation of Fractional-Order Hopfield Networks with Memristive Synapse by Andrés Anzo-Hernández, Ernesto Zambrano-Serrano, Miguel Angel Platas-Garza, Christos Volos

    Published 2024-10-01
    “…When integrated into systems like Hopfield neural networks, memristors enable the study of complex dynamic behaviors, such as chaos and multistability. …”
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