Sepsis Presentation, Interventions, and Outcome Differences Among Men and Women in the Emergency Department by Joseph O’Brien, Jon W. Schrock

“…Objectives: Sepsis is a common presentation to the emergency department (ED) and represents a life-threatening syndrome with high mortality rates. …”
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Characterization of the Complete Mitochondrial Genome of <i>Angulyagra polyzonata</i> and Its Phylogenetic Status in Viviparidae by Shengjie Zhang, Kangqi Zhou, Xianhui Pan, Yong Lin, Jinxia Peng, Junqi Qin, Zhenlin Ke, Yaoquan Han, Zhong Chen, Xuesong Du, Wenhong Li, Pinyuan Wei, Dapeng Wang

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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…It aims to provide babies with a healthy start to life by combining parenting skills training with strategies to enhance individual well-being and couple adjustment. …”
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Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study by Gary S Collins, Sarah E Lamb, Sally Hopewell, Daniel Prieto-Alhambra, Andrew Judge, Amar Rangan, Andrew J Carr, Jonathan L Rees, Nigel K Arden, Katherine Edwards, Tim A Holt, Anjali Shah, Antonella Delmestri, Rafael A Pinedo-Villanueva

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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…The results of the qualitative questionnaire and open interview with the sample members, after taking notes and transferring to the system, were analyzed using coding and the data-based method and Maxqda software, and the output and the final model were reported. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

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Perspectives of Hispanic and Latinx Community Members on AI-Enabled mHealth Tools: Qualitative Focus Group Study by Stephanie A Kraft, Shaan Chopra, Miriana C Duran, Janet A Rojina, Abril Beretta, Katherine I López, Russell Javan, Benjamin S Wilfond, Margaret Rosenfeld, James Fogarty, Linda K Ko

“…We developed a qualitative codebook using deductive and inductive methods and then coded deidentified transcripts using the constant comparison method. …”
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Using electronic health record data to establish a chronic kidney disease surveillance system in China: protocol for the China Kidney Disease Network (CK-NET)-Yinzhou Study by Yu Yang, Peng Shen, Hongbo Lin, Luxia Zhang, Minghui Zhao, Jinwei Wang, Beiyan Bao, Guilan Kong, Xiaoyu Sun, Guohui Ding, Bixia Gao, Chao Yang

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Assembly and comparative analysis of the complete mitochondrial genome of red raspberry (Rubus idaeus L.) revealing repeat-mediated recombination and gene transfer by Huajie Zhang, Minghui Yan, Lijuan Li, Zhuo Jiang, Ye Xiong, Yusheng Wang, Caleb Onoja Akogwu, Olutayo Mary Tolulope, Hao Zhou, Yanxia Sun, Hengchang Wang

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A person-centred primary care pharmacist-led osteoporosis review for optimising medicines (PHORM): a protocol for the development and co-design of a model consultation intervention by Andrew Sturrock, Robert Horne, Emma Clark, Toby Helliwell, Tracy Finch, Ian Maidment, Zoe Paskins, Shona Haining, Laurna Bullock, Robin Hyde, Meaghan Grabrovaz, Claire Pryor, Louise Statham

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Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: Results of the chronic pain cohort by Jeffery A. Dusek, Qi Gao, Ryung S. Kim, Donald I. Abrams, Benjamin Kligler, Natalie L. Dyer, Kathryn Hansen, Eric J. Roseen, M. Diane McKee

“…Diagnostic and billing codes were extracted data from patients’ health records. …”
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Altered branched chain ketoacids underlie shared metabolic phenotypes in type 1 diabetes and maple syrup urine disease by Domenico Roberti, Abby L. Grier, Julie A. Reisz, Fara Vallefuoco, Alicia Key, Shaun Bevers, Monika Dzieciatkowska, Travis Nemkov, Marcella Contieri, Angela Zanfardino, Philip J. Norris, Michael P. Busch, Vienna Kauffman, Holmes D. Morton, Eric J. Earley, Grier P. Page, Pierluigi Marzuillo, Angelo D’Alessandro

“…Abstract Background Diabetic ketoacidosis is an acute, potentially life-threatening, metabolic complication and often first presentation of type 1 diabetes (T1D) mellitus. …”
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Whole genome sequence of petroleum hydrocarbon degrading novel strain Microbacter sp. EMBS2025 isolated from Chilika Lake, Odisha, India by Anuraj Nayarisseri, Khushboo Sharma, Arshiya Khan, Radhika Swami, Rinku Chaudhary, Juhi Sharma, Navpreet Kaur, Jyotsana Kharate, Vasudha Rathore, Leena Prajapati, Srinivas Bandaru, Francisco Jaime Bezerra Mendonça Junior, Marcus T. Scotti, Luciana Scotti

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Eco-anxiety, climate concern, and fatalistic outlooks: Insights from U.S. crisis text conversations on climate distress by Jennifer D. Runkle, Kelsey Herbst, Sophie Ryan, Kelly Sewell, Ashley Mallare, Ian Berry, Emma Getz, Arden McKee, Martie P. Thompson, Margaret M. Sugg

“…A comprehensive codebook was developed, incorporating predetermined and emergent codes for climate change exposures, crisis flags, emotional responses, and special topics. …”
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Research status and hotspots of hypothermia and human diseases: a bibliometric analysis by Wei-Xuan Li, Na-Na Han, Qian-Yu Ji, Xue-Tong Dong, Chao-Long Lu, Song-Jun Wang

“…BackgroundHypothermia has been strongly associated with human diseases; it affects life safety. Therapeutic hypothermia generates good results for certain diseases, without serious complications. …”
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Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…We found evidence of some inconsistency across the networks assessing sleep quality and quality of life using the Fibromyalgia Impact Questionnaire. …”
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Trial to assess the tolerability of using felodipine to upregulate autophagy as a treatment of Huntington’s disease (FELL-HD): a phase II, single-centre, open-label, dose-finding t... by Roger A Barker, Laura Oakley, Emma Cutting, David C Rubinsztein, Dimitrios Apostolopoulos, Nikolaos Demiris, Katie Andresen, Amy H Evans, Alimu Dayimu, Katherine Bongaerts, Robyn Staples, Wendy Gooding

“…It is caused by a Cytosine-adenin-guanine (CAG) expansion in exon 1 of the huntingtin gene which codes for mutant huntingtin (mHTT) that over time accumulates in cells, causing dysfunction and then death through new toxic gain-of-function mechanisms. …”
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The journey of medical field students: uncovering medical student syndrome, personality traits, and their interactions by Mohamed Abdelfatah Abdellatif, Heba A. Abdel Salam, Hossam Tharwat Ali, Salma Mohammed Hussein, Ahmed Ali Abdalla, Mohamed Khaled Khorkhash, Feras Ammar Alsabbagh, Nesreen Kamel Elsayed, Fatma Ahmed Ibrahim, Samar A. Amer

“…The collected data was coded and analyzed using R statistical software. …”
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Transcriptomic analysis of intracellular RNA granules and small extracellular vesicles: Unmasking their overlap in a cell model of Huntington's disease by Deepti Kailash Nabariya, Lisa Maria Knüpfer, Patrick Hartwich, Manuela S. Killian, Florian Centler, Sybille Krauß

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Function of a novel human gene TOX promoting cell proliferation by DENG Weiwei, LI Jing, GAO Peng, HAO Dongxia, ZHANG Lu, SHI Taiping, WANG Ying

“…Cell proliferation is a highly ordered operation process, and it plays an important role in the life activities. The abnormal regulation of cell proliferation often causes a variety of disease occurrence and development. …”
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