Exploring the genomic landscape of the GP63 family in Trypanosoma cruzi: Evolutionary dynamics and functional peculiarities. by Luisa Berná, María Laura Chiribao, Sebastián Pita, Fernando Alvarez-Valin, Adriana Parodi-Talice

“…Transcription patterns across different life cycle stages are not homogenous. Instead, some GP63 groups have higher mRNA levels in the infective trypomastigote stage, suggesting a potential role in host invasion. …”
Get full text

Genomic sequence data of Thiohalocapsa marina: a sulfur-oxidizing bacterium prevalent in treated municipal wastewater and commercial shrimp hatchery effluents by Guillermo Reyes, Irma Betancourt, Betsy Andrade, Yessenia Pozo, Lita Sorroza, Luis E. Trujillo, Bonny Bayot

Get full text

A Methodology to capture the single blade loads on a cross-flow tidal turbine flume model by Timo Bennecke, Shokoofeh Abbaszadeh, Karla Ruiz-Hussmann, Paul Joedecke, Pierre-Luc Delafin, Christian-Toralf Weber, Stefan Hoerner

“…CFTT are attractive for the exploitation of tidal energy, because of high area-based power densities of such turbine arrays, a simple design and the ability to operate under varying flow conditions. …”
Get full text

Dysregulation in the Unfolded Protein Response in the FGR Rat Pancreas by Xiaomei Liu, Yanyan Guo, Jun Wang, Liangliang Zhu, Linlin Gao

“…Eighty-four UPR pathway components in the pancreas were investigated by quantitative PCR arrays and confirmed by qPCR and western blotting. …”
Get full text

A Novel Algorithm for the Decomposition of Non-Stationary Multidimensional and Multivariate Signals by Roberto Cavassi, Antonio Cicone, Enza Pellegrino, Haomin Zhou

“…The potentiality of the proposed method is demonstrated through applications to artificial and real-life signals, highlighting its versatility and effectiveness in decomposing multidimensional and multivariate non-stationary signals. …”
Get full text

Efficiency of rehabilitation treatment of patients with post-COVID syndrome by A. A. Zuikova, D. Yu. Bugrimov, O. N. Krasnorutskaya

“…A thorough analysis of large arrays of patients showed that residual symptoms in people with microbiological normalization (i. e., with negative results of the SARS-CoV-2 virus as a criterion for the effectiveness of etiotropic treatment) represent a complex of clinical manifestations that have a single etiopathogenesis, and thus the following is formed concept as post-covid syndrome. …”
Get full text

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity. by James P Hewitson, Al C Ivens, Yvonne Harcus, Kara J Filbey, Henry J McSorley, Janice Murray, Stephen Bridgett, David Ashford, Adam A Dowle, Rick M Maizels

“…Both adult and L4 ES contain extensive but distinct arrays of Venom allergen/Ancylostoma secreted protein-Like (VAL) members, with acetylcholinesterases (ACEs) and apyrase APY-3 particularly abundant in L4 ES. …”
Get full text

Artificially intelligent nasal perception for rapid sepsis diagnostics by Joonchul Shin, Gwang Su Kim, Seongmin Ha, Taehee Yoon, Junwoo Lee, Taehoon Lee, Woong Heo, Kyungyeon Lee, Seong Jun Park, Sunyoung Park, Jaewoo Song, Sunghoon Hur, Hyun-Cheol Song, Ji-Soo Jang, Jin-Sang Kim, Hyo-Il Jung, Chong-Yun Kang

“…Abstract Sepsis, a life-threatening disease caused by infection, presents a major global health challenge due to its high morbidity and mortality rates. …”
Get full text

Resistome, virulome, anti-defense mechanisms, and prophages in Helicobacter pylori strains in Asia by Tushar Midha, Navoneel Giri, Somesh Baranwal

“…Twenty-eight genomes carried CRISPR arrays, whereas 22 contained prophage elements with 25 VF genes and no antibiotic resistance genes. …”
Get full text

Open-Source Software for Building-Integrated Photovoltaic Tiling for Novelty Architecture by Alexander W. H. Chin, Koami Soulemane Hayibo, Joshua M. Pearce

“…The buildings’ energy performance was compared to conventional ground-based PV systems, and the results showed that the conventional arrays generate more energy per unit power than the BIPVs. …”
Get full text

High-throughput fluorescence lifetime imaging flow cytometry by Hiroshi Kanno, Kotaro Hiramatsu, Hideharu Mikami, Atsushi Nakayashiki, Shota Yamashita, Arata Nagai, Kohki Okabe, Fan Li, Fei Yin, Keita Tominaga, Omer Faruk Bicer, Ryohei Noma, Bahareh Kiani, Olga Efa, Martin Büscher, Tetsuichi Wazawa, Masahiro Sonoshita, Hirofumi Shintaku, Takeharu Nagai, Sigurd Braun, Jessica P. Houston, Sherif Rashad, Kuniyasu Niizuma, Keisuke Goda

Get full text

Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases by Carina Bernardo, Subhayan Chattopadhyay, Natalie Andersson, Pontus Eriksson, Benjamin Medle, Lena Tran, Nour al dain Marzouka, Adam Mattsson, Aymeric Zadoroznyj, Malin Larsson, Fredrik Liedberg, Mattias Höglund, Gottfrid Sjödahl

Get full text

Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation by Matthew Booker, Sarah Voss, Nicky Harris, William Hollingworth, Nouf Jeynes, Hazel Taylor, Kirsty Garfield, Helen Baxter, Jonathan Benger, Andy Gibson, Trudy Goodenough, Justin Jagosh, Kim Kirby, Cathy Liddiard, Alyesha Proctor, Sarah Purdy, Behnaz Schofield, Hannah Stott, Grace Scrimgeour, Nicola Walsh

“…There was no important difference in quality-adjusted life-years (QALYs) between PGP and non-PGP sites. …”
Get full text

Nano hierarchical hill-like structure with TA1 surface manufactured by LIPSS for anti-corrosion and anti-icing by Guolong Wang, Ji Wang, Kaijie Cheng, Kun Yang, Wenwu Zhang

“…The composite structure consists of micro hill arrays and surface nano hierarchical structures. We investigate the effects of laser power and scanning speed on the microstructure of the TA1 surface. …”
Get full text

A Comparison Study of High-Temperature Low-Cycle Fatigue Behaviour and Deformation Mechanisms Between Incoloy 800H and Its Weldments by Wenjing Li, Lin Xiao, Lori Walters, Greg Kasprick, Robyn Sloan

“…However, the weldments with the Haynes 230 filler metal demonstrated an improved fatigue life at the low strain amplitude compared to both Incoloy 800H and the weldment with the Inconel 82 filler metal. …”
Get full text

Methylome analysis and epigenetic changes associated with menarcheal age. by Christiana A Demetriou, Jia Chen, Silvia Polidoro, Karin van Veldhoven, Cyrille Cuenin, Gianluca Campanella, Kevin Brennan, Françoise Clavel-Chapelon, Laure Dossus, Marina Kvaskoff, Dagmar Drogan, Heiner Boeing, Rudolf Kaaks, Angela Risch, Dimitrios Trichopoulos, Pagona Lagiou, Giovanna Masala, Sabina Sieri, Rosario Tumino, Salvatore Panico, J Ramón Quirós, María-José Sánchez Perez, Pilar Amiano, José María Huerta Castaño, Eva Ardanaz, Charlotte Onland-Moret, Petra Peeters, Kay-Tee Khaw, Nick Wareham, Timothy J Key, Ruth C Travis, Isabelle Romieu, Valentina Gallo, Marc Gunter, Zdenko Herceg, Kyriacos Kyriacou, Elio Riboli, James M Flanagan, Paolo Vineis

“…Epigenetic changes may be modulated by menarcheal age, or the association may be a mirror of other important changes in early life that have a detectable effect on both methylation levels and menarcheal age.…”
Get full text

Possible Clinical Effects of Ketoconazole on Sorafenib-induced Hand–Foot Skin Reaction and Cytoprotection Mechanisms of Antifungal Agents against Multikinase Inhibitor-induced Kera... by Rui Kato, Yayoi Kamata, Mitsutoshi Tominaga, Ryoma Kishi, Takahide Kaneko, Akira Tsujimura, Yasushi Suga, Kenji Takamori

“…Multikinase inhibitors (MKIs) have been associated with serious skin disorders, including hand–foot skin reaction (HFSR), which impair patient quality of life, often disrupting activities of daily living necessitating dose reduction or discontinuation. …”
Get full text

Polycyclic Aromatic Hydrocarbon and CO(2–1) Emission at 50–150 pc Scales in 70 Nearby Galaxies by Ryan Chown, Adam K. Leroy, Karin Sandstrom, Jérémy Chastenet, Jessica Sutter, Eric W. Koch, Hannah B. Koziol, Lukas Neumann, Jiayi Sun, Thomas G. Williams, Dalya Baron, Gagandeep S. Anand, Ashley. T. Barnes, Zein Bazzi, Francesco Belfiore, Frank Bigiel, Alberto Bolatto, Médéric Boquien, Yixian Cao, Mélanie Chevance, Dario Colombo, Daniel A. Dale, Jakob den Brok, Oleg V. Egorov, Cosima Eibensteiner, Eric Emsellem, Hamid Hassani, Jonathan D. Henshaw, Hao He, Jaeyeon Kim, Ralf S. Klessen, Kathryn Kreckel, Kirsten L. Larson, Janice C. Lee, Sharon E. Meidt, Eric J. Murphy, Elias K. Oakes, Eve C. Ostriker, Hsi-An Pan, Debosmita Pathak, Erik Rosolowsky, Sumit K. Sarbadhicary, Eva Schinnerer, Yu-Hsuan Teng, David A. Thilker, Tony D. Weinbeck, Elizabeth J. Watkins

Get full text

Searching for Neutrinoless Double-Beta Decay of 130Te with CUORE by D. R. Artusa, F. T. Avignone, O. Azzolini, M. Balata, T. I. Banks, G. Bari, J. Beeman, F. Bellini, A. Bersani, M. Biassoni, C. Brofferio, C. Bucci, X. Z. Cai, A. Camacho, L. Canonica, X. G. Cao, S. Capelli, L. Carbone, L. Cardani, M. Carrettoni, N. Casali, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, I. Dafinei, A. Dally, V. Datskov, A. De Biasi, M. M. Deninno, S. Di Domizio, M. L. di Vacri, L. Ejzak, D. Q. Fang, H. A. Farach, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, J. Goett, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, K. M. Heeger, R. Hennings-Yeomans, H. Z. Huang, R. Kadel, K. Kazkaz, G. Keppel, Yu. G. Kolomensky, Y. L. Li, C. Ligi, X. Liu, Y. G. Ma, C. Maiano, M. Maino, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, S. Nisi, C. Nones, E. B. Norman, A. Nucciotti, T. O’Donnell, F. Orio, D. Orlandi, J. L. Ouellet, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, M. Pedretti, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, E. Previtali, V. Rampazzo, C. Rosenfeld, C. Rusconi, E. Sala, S. Sangiorgio, N. D. Scielzo, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, W. D. Tian, C. Tomei, S. Trentalange, G. Ventura, M. Vignati, B. S. Wang, H. W. Wang, L. Wielgus, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, C. Zarra, B. X. Zhu, S. Zucchelli

“…The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for 0νββ decay of 130Te using an array of 988 TeO2 crystal bolometers operated at 10 mK. …”
Get full text

Widespread splicing changes in human brain development and aging by Pavel Mazin, Jieyi Xiong, Xiling Liu, Zheng Yan, Xiaoyu Zhang, Mingshuang Li, Liu He, Mehmet Somel, Yuan Yuan, Yi‐Ping Phoebe Chen, Na Li, Yuhui Hu, Ning Fu, Zhibin Ning, Rong Zeng, Hongyi Yang, Wei Chen, Mikhail Gelfand, Philipp Khaitovich

Get full text