Proteomics and metabolomics analyses of mechanism underlying bovine sperm cryoinjury by Renzheng Zhang, Xiuyuan Wang, Ruili Liu, Yanfang Mei, Xiuping Miao, Jiaxu Ma, Lei Zou, Qiuyue Zhao, Xuejin Bai, Yajuan Dong

“…Results The results indicate that low levels of ROS and high degrees of MMP and ATP play a critical role in the survival of HMS during the freezing process. …”
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Enhancing Campus Mobility: Simulated Multi-Objective Optimization of Electric Vehicle Sharing Systems Within an Intelligent Transportation System Frameworks by Omar S. Aba Hussen, Shaiful J. Hashim, Nasri Sulaiman Member, S.A.R. Alhaddad, Bassam Y. Ribbfors, Masanobu Umeda, Keiichi Katamine

“…The use of dynamic values for dual relocation thresholds and charge-to-work levels further optimized the process, reducing operational costs significantly, with a lesser impact on unserved demands across both scenarios. …”
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Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity by Brian M Ortmann

“…Consequently, understanding the cellular mechanisms underlying HIF activation and its downstream effects has become crucial to developing targeted cancer therapies for improving cancer patient outcomes and represents a key step towards precision medicine.Recent advancements in drug development have led to the emergence of HIF inhibitors, which aim to disrupt HIF-driven processes in cancer providing therapeutic benefit. …”
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L-Borneol 7-O-[β-D-Apiofuranosyl-(1→6)]-β-D-Glucopyranoside Alleviates Myocardial Ischemia-Reperfusion Injury in Rats and Hypoxic/Reoxygenated Injured Myocardial Cells via Regulati... by Ziyi Tong, Gaowen Li, Chengxiao Su, Liyan Zhou, Ling Zhang, Qun Chen, Qing Xia

“…The purpose was to examine the effects of LBAG on myocardial I/R injury (MIRI) in rats and H9c2 cells treated with hypoxia/reoxygenation (H/R). …”
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Dihydroquercetin attenuated Prevotella copri-caused intestinal injury by modulating gut microbiota and bile acids in weaned piglets by Long Wang, Ruizhi Hu, Siqi Ma, Xizi Yang, Jiatai Gong, Hongkun Xiang, Mingkun Shi, Xupeng Yuan, Liang Chen, Hongfu Zhang, Bie Tan, Xi He, Jianhua He, Shusong Wu

“…Gut microbiota disruption during the weaning process is a significant factor of intestinal injury. …”
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Is Form-Focused Instruction Really a Waste of Time? A Review of Past Mistakes and Future Possibilities through the Analysis of Input Enhancement by Andrew Schenck, Matthew Baldwin

“…When viewed through a generic, one-size-fits-all perspective, use of input enhancement does not appear effective. Through analysis of individual grammatical features and different learner proficiency levels, a significant impact may be revealed. …”
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Using omega 3 as an anti-aging treatment by Carlos Iván Zavala Naranjo

“…The available literature shows the effect and benefit of these fatty acids in the aging process, which constitute clinical therapies at the dermatological level and in areas of plastic surgery. …”
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DOCK4 Is a Platinum-Chemosensitive and Prognostic-Related Biomarker in Ovarian Cancer by Qianqian Zhao, Jie Zhong, Ping Lu, Xiao Feng, Ying Han, Chenqi Ling, Wenke Guo, Weijin Zhou, Fudong Yu

“…Several reports point out that PPARs can also have an effect on the sensitivity of tumor cells to platinum-based chemotherapy drugs. …”
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Deep Learning Image Feature Recognition Algorithm for Judgment on the Rationality of Landscape Planning and Design by Bin Hu

“…This paper classifies landscape behavior based on this model for full convolutional neural network landscape images and demonstrates the effectiveness of using the model. In terms of landscape image processing, the image evaluation provides a certain basis.…”
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What is a recognized mechanism for transforming big data analytics into firm performance? A meta-analysis from cultural view by Zongyuan Liu, Harcharanjit Singh Mahinder Singh, Fatema Al Shibli

“…Secondly, OA partially mediates the BDA–FP relationship, especially at the process level. Moreover, individualism and indulgence moderate the BDA–OA relationship, while uncertainty avoidance and long-term orientation moderate the OA–FP relationship at the marginal significance level. …”
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Transcription Factor E2F-1 Is Upregulated in Human Gastric Cancer Tissues and Its Overexpression Suppresses Gastric Tumor Cell Proliferation by Qiang Xiao, Lei Li, Yubo Xie, Ning Tan, Changqing Wang, Junyi Xu, Keyi Xia, Kevin Gardner, Qingdi Q. Li

“…The E2F family members play a critical role in cell cycle regulation and other biological processes in the cell. To better understand the involvement of E2F-1 in the development and progression of gastric tumors, we investigated the mutation and expression of E2F-1 in human gastric cancer tissues and the effect of E2F-1 overexpression on the proliferation of gastric carcinoma cells. …”
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The Impact of Social Media on the Choice of Dental Implant Treatment by Kuddusi Akbulut, Funda Gökçe Akbulut

“…The aim of this study is to determine the effect of information about dental implant treatment shared on social media on patients' treatment decision processes.Materials and Methods: The study was designed as a web-based survey study. …”
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GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia by Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui

“…Recent studies have indicated that the transcription factor GATA1 may be implicated in the pathological processes of PE, but the underlying mechanism remains elusive. …”
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Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms by Lamiae Azouggagh, Noelia Ibáñez-Escriche, Marina Martínez-Álvaro, Luis Varona, Joaquim Casellas, Sara Negro, Cristina Casto-Rebollo

“…ML models exploring maternal, paternal and heterosis effects showed varying levels of classification performance, with the paternal effect scenario being the best, achieving a mean Area Under the ROC curve (AUROC) of 0.74 using the Catboost (CB) algorithm. …”
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Lactococcus lactis D4 Decreases NF-κB and α-SMA in Rat Models of Obstructive Jaundice by Avit Suchitra, Alvarino Alvarino, Eryati Darwin, Harnavi Harun, Muhammad Iqbal Rivai, Ade Sukma

“…This study was conducted to evaluate the effects of LLD4 on NF-κB, α-SMA, and IL-6 in obstructive jaundice rat models. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…Here, we tested the compliance and effectiveness of a Multidomain Lifestyle Intervention Program using the mini-program, Cognitive Evergreenland, (MLIP-CE), based on the Health Action Process Approach model to support home-based intervention in older adults with SCD. …”
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HEMPSEED AND COTTONSEED OILS IN THE ACCESSIONS FROM THE VIR COLLECTION AS SOURCES OF FUNCTIONAL FOOD INGREDIENTS by S. V. Grigoryev, T. V. Shelenga, K. V. Illarionova

“…Industrial hemp is still cultivated and processed domestically. In the 1950s, industrial cotton was cultivated on a hundred thousand hectares in the country, and now there are signs of its restored growing. …”
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Research and application of 5G cloud-network-edge-end integrated in-depth security protection system by Guoxin ZHANG

“…A 5G cloud-network-edge-end integrated in-depth security protection implementation scheme was innovatively proposed, the network security protection system of 5G customized network was explored, and the basic architecture, characteristics, implementation scheme and application effect of the system were introduced.In the implementation plan, two key points were emphasized.Firstly, by deploying the security system of the four aspects of the 5G cloud network, the edge and the end, the multi-level and multi-dimensional security protection capability was formed.Secondly, the operation process of the adaptation system, including one-key reinforcement, security defense, situational awareness and one-key emergency response was established.Finally, the practical application effect of the 5G cloud-network-edge-end integrated in-depth security protection system was given.…”
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RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection by Ignacio Silva-Llanes, Ignacio Silva-Llanes, Ignacio Silva-Llanes, Enrique Madruga, Enrique Madruga, Ana Martínez, Ana Martínez, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker

“…However, this RIPK1 inhibitor failed to protect against the neurodegeneration caused by elevated TAUP301L levels in the hippocampal region. These results suggest that although inhibiting RIPK1 activity may help reduce TAU-related astrogliosis in the brain, the complexity of the inflammatory pathways involved could explain the absence of neuroprotective effects against TAU-induced neurodegeneration.…”
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Biochanin a modulates steroidogenesis and cellular metabolism in human granulosa cells through TAS2Rs activation: a spotlight on ovarian function by Francesca Paola Luongo, Sofia Passaponti, Alesandro Haxhiu, Irene Ortega Baño, Rosetta Ponchia, Giuseppe Morgante, Paola Piomboni, Alice Luddi

“…These effects were reversed by TAS2R antagonists. Additionally, BCA treatment decreased intracellular Ca2+ levels (p < 0.01) and reduced lipid droplet size (p < 0.001), both of which were counteracted by antagonists. …”
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