Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy by Ting Chen, Lin Zhao, Jiaojiao Zhang, Mingyi Ju, Zhuoyuan Deng, Minjie Wei, Lianghua Ma

“…To investigate the efficacy of prophylactic IL-23 blockade administration to prevent irAEs, refer to a previous study, we constructed two irAEs murine models, including dextran sulfate sodium salt (DSS)-induced colitis murine model and a combined-ICIs-induced irAEs murine model. …”
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A Novel 14-Gene Panel Associated With Efferocytosis for Predicting Pancreatic Cancer Prognosis Through Bulk and Single-Cell Databases by Yaheng Wu, Lin Zhao, Dingyan Yi, Zhihua Tian, Bin Dong, Chunxiang Ye, Jingtao Liu, Huachong Ma, Wei Zhao

“…Least absolute shrinkage and selection operator (LASSO) regression was subsequently employed to construct an ER risk scoring system using deep learning, based on the following formula: LGALS3, EMP1, ASPH, and FNDC3B, collectively termed the “LEAF” panel. …”
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Nivel de satisfacción de la simulación clínica en estudiantes de fisioterapia de una institución de educación superior de la ciudad de Cali-Colombia (Satisfaction level of clinical... by Nathali Carvajal, Jorge Enrique Daza Arana, Diana Carolina Urrea Arango, Alejandro Segura Ordoñez, Camila Vásquez Moreno, Alvaro Santiago Solarte Rosero, Karen Pinto Narváez

“…Results: In high and low fidelity clinical simulation, the items with the highest satisfaction were "teacher training is adequate" with a mean of 4.42, "The role of the leader in the simulation is necessary for teamwork" with a mean of 4.17, and "Debriefing provides verbal feedback and constructive criticism" with a mean of 4.16. Conclusion: Students are satisfied with the clinical simulation strategy, being this a useful pedagogical tool in learning, skill development and acquisition of competencies. …”
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Biological contingency and adaptation to celibacy among girls aged 35 and over in Yazd city by Ahmad Kalateh Sadati, Fatemeh Jafari Naeimi, Sara Sadeghieh, Zahra Sadeghian Moghadam

“…. & Luckmann, T. (1994). The Social Construction of Reality: A Treatise in the Sociology of Knowledge. …”
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Radiomic analysis of patient and interorgan heterogeneity in response to immunotherapies and BRAF-targeted therapy in metastatic melanoma by Riyue Bao, Yana G Najjar, Diwakar Davar, John M Kirkwood, Jason John Luke, Sarah Newman, Hassane M Zarour, Afsaneh Amouzegar, Rivka R Colen, Murat Ak, Priyadarshini Mamindla, Serafettin Zenkin, Vishal Peddagangireddy, Sarah Behr, Alexandra G Tompkins, Zane N Gray, Rebekah E Dadey, Nasim Batavani, Nursima Ak, Taha Yasin Pak, Mohammadreza Amjadzadeh, Amy Goodman, Darcy L Ploucha, Curtis Tatsuoka

“…Overall and organ-specific machine-learning models were constructed to predict disease control (DC) versus progressive disease (PD) using XGBoost. 291 patients with MEL were identified, including 242 ICI (91 I+N, 151 PD-1) and 49 BRAF. 667 metastases were analyzed, including 541 ICI (236 I+N, 305 PD-1) and 126 BRAF. …”
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Radiomic Model Associated with Tumor Microenvironment Predicts Immunotherapy Response and Prognosis in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma by Jie Sun, Xuewei Wu, Xiao Zhang, Weiyuan Huang, Xi Zhong, Xueyan Li, Kaiming Xue, Shuyi Liu, Xianjie Chen, Wenzhu Li, Xin Liu, Hui Shen, Jingjing You, Wenle He, Zhe Jin, Lijuan Yu, Yuange Li, Shuixing Zhang, Bin Zhang

“…A combined model was constructed by integrating clinical and radiomic data. …”
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Establishing the VR-haptic thinkers group: Insights and progress in dental training technologies by Szabolcs Felszeghy, Mikko Liukkonen, Nicla Flacco, Mahmoud M. Bakr, Sarah Rampf, Simona-Georgiana Schick, Maria F. Sittoni-Pino, Kristin Ackerman, Santiago Arias-Herrera, Ben Audsley, Santiya Bell, Samantha Byrne, Giorgia Carpegna, Mark R. Durham, Kandace Gourley, Outi Huhtela, Hanna Hytönen, Carlos López-Roig, David Morton, Masako Nagasawa, Cesar Orsini, Damiano Pasqualini, Amitha Ranauta, María P. Rodríguez-Hopp, Anna L. Suominen, Jorge A. Tricio-Pesce, Michael Wolcott, Muhammad A. Shazib, Thomas J. Greany, Michael Lampe, Margrit Maggio, Sompop Bencharit, Rebecca Stolberg, Gülsün Gül, Barry Quinn, Murat Mutluay

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Catalonia Suicide Risk Code Epidemiology (CSRC-Epi) study: protocol for a population-representative nested case–control study of suicide attempts in Catalonia, Spain by Lars Mehlum, Ronald C Kessler, Rosa Morros, Gemma Vilagut, Jordi Alonso, Philippe Mortier, Beatriz Puértolas Gracia, Ana De Inés Trujillo, Itxaso Alayo Bueno, Laura Ballester Coma, María Jesús Blasco Cubedo, Narcís Cardoner, Cristina Colls, Matilde Elices, Anna Garcia-Altes, Manel Gené Badia, Javier Gómez Sánchez, Mario Martín Sánchez, Bibiana Prat Pubill, Ping Qin, Diego Palao, Víctor Pérez Sola

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Graphical representation of global water models by H. Müller Schmied, H. Müller Schmied, S. N. Gosling, M. Garnsworthy, L. Müller, C.-E. Telteu, A. K. Ahmed, L. S. Andersen, J. Boulange, P. Burek, J. Chang, H. Chen, L. Gudmundsson, M. Grillakis, L. Guillaumot, N. Hanasaki, A. Koutroulis, R. Kumar, G. Leng, J. Liu, J. Liu, J. Liu, X. Liu, I. Menke, I. Menke, V. Mishra, V. Mishra, Y. Pokhrel, O. Rakovec, O. Rakovec, L. Samaniego, L. Samaniego, Y. Satoh, H. L. Shah, M. Smilovic, T. Stacke, E. Sutanudjaja, W. Thiery, A. Tsilimigkras, Y. Wada, N. Wanders, T. Yokohata

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Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice by Xin Wang, Wei Wu, Guang Yang, Xue-Wei Yang, Xu Ma, Dan-Dan Zhu, Kabir Ahmad, Khizar Khan, Ying-Zi Wang, Ao-Ran Sui, Song-Yu Guo, Yue Kong, Bo Yuan, Tian-Yuan Luo, Cheng-Kang Liu, Peng Zhang, Yue Zhang, Qi-Fa Li, Bin Wang, Qiong Wu, Xue-Fei Wu, Zhi-Cheng Xiao, Quan-Hong Ma, Shao Li

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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…[xiii] Only 7 percent of renal transplant programs use formal criteria for subjective psychosocial assessments, while no pediatric solid organ transplant programs use formal, explicit, or uniform review to assess developmental delays and psychosocial support.…”
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Training teachers to teach PISA-like reading: A case in Indonesia by Emi Emilia, Eva Tuckyta Sari Sujatna, Nia Kurniasih

“…It is recommended that the training program be conducted in different contexts, involving more teachers to help students learn to read and succeed in PISA reading.…”
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The impact of second language teacher education on the development of pre-service teachers’ pedagogical beliefs by Kenneth Richter

“…This suggests that with time, internalized learnings from the program may have an opportunity to come to the fore and positively impact teacher practice.…”
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Supported biopsychosocial self-management for back-related leg pain: a randomized feasibility study integrating a whole person perspective by Brent Leininger, Roni Evans, Carol M. Greco, Linda Hanson, Craig Schulz, Michael Schneider, John Connett, Francis Keefe, Ronald M. Glick, Gert Bronfort

“…At 12 weeks, 95% of participants in the self-management group reported engaging in self-management practices learned in the program and 77% of medical care participants reported taking medications as prescribed. …”
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Real-World Temperature Data From the Gulf of Mexico: Seasonality and Effect of the Loop Current With an Accessible Hands-On Activity by Andrée L. Ramsey, Mary Carla Curran, Amy S. Bower

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A case study of the development of a valid and pragmatic implementation science measure: the Barriers and Facilitators in Implementation of Task-Sharing Mental Health interventions... by Lawrence H. Yang, Judy K. Bass, PhuongThao D Le, Ritika Singh, Dristy Gurung, Paola R. Velasco, Margaux M. Grivel, Ezra Susser, Charles M. Cleland, Rubén Alvarado, Brandon A. Kohrt, Arvin Bhana

“…The process and lessons learned will aid in the teaching, practice and research of IS measurement development. …”
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SGPLane: Efficient lane detection via sampled grid points for autonomous driving by Xuewei Tang, Mengmeng Yang, Kun Jiang, Tuopu Wen, Benny Wijaya, Diange Yang

“…Specifically, we use sampled gird points to express lane lines and construct a network for the special lane format, which is called SGPLane. …”
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Making room for meaningful inclusion of Indigenous and local knowledge in global assessments: our experiences in the values assessment of the Intergovernmental Science-Policy Platf... by Mariaelena Huambachano, Gabriel R Nemogá Soto, Tuyeni H Mwampamba

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Device Independent Quantum Private Queries Based on Quantum Key Distribution by Li Liu, Qingshan Du, Xu Gao

“…To overcome this drawback, we propose a device independent QPQ protocol based on QKD with imperfect sources and detectors. By constructing the semi-definite programming optimization problem, we give the CHSH test threshold and prove the correctness of our protocol. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…Debora Diniz and Giselle Carino, “What Can Be Learned from the Global South on Abortion and How We Can Learn?…”
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