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  1. 501

    Analysis of Voice, Speech, and Language Biomarkers of Parkinson’s Disease Collected in a Mixed Reality Setting by Milosz Dudek, Daria Hemmerling, Marta Kaczmarska, Joanna Stepien, Mateusz Daniol, Marek Wodzinski, Magdalena Wojcik-Pedziwiatr

    Published 2025-04-01
    “…The findings hold promise for broader clinical applications, advancing the diagnostic landscape for neurodegenerative disorders.…”
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    Article
  2. 502

    Epitranscriptomic analysis reveals clinical and molecular signatures in glioblastoma by Glaucia Maria de Mendonça Fernandes, Wesley Wang, Saman Seyed Ahmadian, Daniel Jones, Jing Peng, Pierre Giglio, Monica Venere, José Javier Otero

    Published 2025-04-01
    “…Novel differences in N6-Methyladenosine (m6A) RNA methylation patterns between these groups are identified in the first biopsy. …”
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    Article
  3. 503

    Integrating metabolism gene clusters and tumor immune microenvironment in head and neck squamous cell carcinoma by Meina Lian, Xiaoxia Wang, Zixian Huang, Yudong Wang, Zhiquan Huang

    Published 2025-06-01
    “…TNFAIP6 was further evaluated for its functional role through in vitro assays, including proliferation, migration, and invasion analyses. …”
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    Article
  4. 504

    Carbon Emissions From Low‐Order Streams in a Tropical, High‐Elevation, Peatland Ecosystem Are Mediated by Catchment Morphology by Keridwen M. Whitmore, Amanda G. DelVecchia, Elizabeth Farquhar, Gerard Rocher‐Ros, Esteban Suárez, Diego A. Riveros‐Iregui

    Published 2025-04-01
    “…However, few studies have examined the spatial variability of CO2 concentrations and fluxes occurring within these systems, particularly as a function of catchment morphology. Here we evaluated spatial patterns of CO2 in three tropical, headwater catchments in relation to the river network and stream geomorphology. …”
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    Article
  5. 505

    SmartTrust: a hybrid deep learning framework for real-time threat detection in cloud environments using Zero-Trust Architecture by Umesh Kumar Lilhore, Sarita Simaiya, Roobaea Alroobaea, Abdullah M. Baqasah, Majed Alsafyani, Afnan Alhazmi, Md Monish Khan

    Published 2025-07-01
    “…SmartTrust integrates CNN, LSTM, and Transformer models to analyze spatial and temporal patterns in network traffic and user behaviours. Unlike conventional models, it leverages Reinforcement Learning to enable adaptive decision-making, allowing it to adjust responses based on real-time contextual signals dynamically. …”
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    Article
  6. 506

    Vitamin D and MAFLD: a bibliometric and visual analysis from 2007 to 2024 by Jiaguo Zhang, Sipeng Wu, Junqian Huang, Xuehua Sun, Jianjie Chen, Binyi Shang

    Published 2025-06-01
    “…R6) and VOSviewer (v1.6.20) software, we evaluated publication trends, regional and national contributions, institutional outputs, journal allocation, author collaborations, reference citations, and keyword patterns.ResultsA total of 480 publications were analyzed, demonstrating a consistent annual increase. …”
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    Article
  7. 507

    Arginine methylation modulates tumor fate and prognosis in clear cell renal cell carcinoma by Jiahao Wang, Dan Bao, Xiaochao Chen, Zijie Yu, Weiyu Kong, Chen Xu, Songtao Li, Yulin Yue

    Published 2025-05-01
    “…Single-cell RNA sequencing datasets were employed to evaluate gene expression patterns at the cellular level. …”
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    Article
  8. 508

    Global research trends in sarcopenia: a bibliometric analysis of exercise and nutrition (2005–2025) by Runqian Zhang, Jiaxin Wang, Huijuan Xi, Yue Cheng, Bei Han

    Published 2025-05-01
    “…ObjectivesThis study aimed to evaluate the current research landscape, identify emerging areas of interest, and provide scientific insights for further research in exercise and nutrition for sarcopenia.MethodsA comprehensive bibliometric analysis was conducted using publications retrieved from the Web of Science Core Collection and SCOPUS between January 1, 2005 and January 1, 2025, focusing on exercise and nutritional interventions for sarcopenia. …”
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    Article
  9. 509

    Environmental drivers of the resistome across the Baltic Sea by Joeselle M. Serrana, Francisco J. A. Nascimento, Benoît Dessirier, Elias Broman, Malte Posselt

    Published 2025-04-01
    “…The combined effects of salinity and temperature gradients, alongside nutrient availability, created a complex environmental landscape that shaped the diversity and distribution of the predicted ARGs. …”
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    Article
  10. 510

    Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta by Amy M Inkster, Allison M Matthews, Tanya N Phung, Seema B Plaisier, Melissa A Wilson, Carolyn J Brown, Wendy P Robinson

    Published 2025-03-01
    “…We characterized X chromosome DNAme variation in the placenta relative to sample variables including cell composition, ancestry, maternal age, placental weight, and fetal birth weight, and compared these patterns to other tissues. We also evaluated the relationship between X-linked DNAme and previously reported XCI gene expression status in placenta. …”
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    Article
  11. 511

    A Chemotherapy Response-Related Gene Signature and DNAJC8 as Key Mediators of Hepatocellular Carcinoma Progression and Drug Resistance by Ye Y, Zeng Y, Huang S, Zhu C, Wang Q

    Published 2025-03-01
    “…We constructed a prognostic model using Least Absolute Shrinkage and Selection Operator (LASSO) analysis and assessed its efficacy using Kaplan-Meier survival analysis. Additionally, we evaluated the immune landscape and gene mutation profiles between different chemotherapy response-related gene (CRRG) subtypes. …”
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    Article
  12. 512

    Virtual Avebury: exploring sense of place in a virtual archaeology simulation by Liz Falconer, David Burden, Rosamund Cleal, Ralph Hoyte, Phillip Phelps, Neil Slawson, Nicola Snashall, Kate Welham

    Published 2020-07-01
    “…This paper describes and discusses creating and evaluating a virtual reality simulation of Avebury Stone Circle and Henge complex as it might have appeared and sounded circa 2300 BCE. …”
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    Article
  13. 513

    VPS26A as a Prognostic Biomarker and Therapeutic Target in Liver Hepatocellular Carcinoma: Insights from Comprehensive Bioinformatics Analysis by Hye-Ran Kim, Jongwan Kim

    Published 2025-07-01
    “…<i>Materials and Methods:</i> Multiple databases, including TIMER, UALCAN, HPA, GSCA, KM Plotter, OSlihc, MethSurv, miRNet, OncomiR, LinkedOmics, GeneMANIA, and STRING, were used to evaluate VPS26A expression patterns, prognostic implications, correlations with tumor-infiltrating immune cells (TIICs), epigenetic modifications, drug sensitivity, co-expression networks, and protein–protein interactions in LIHC. …”
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  14. 514
  15. 515

    Revitalizing the Epigenome of Adult Jaw Periosteal Cells: Enhancing Diversity in iPSC-Derived Mesenchymal Stem Cells (iMSCs) by Felix Umrath, Valerie Wendt, Gilles Gasparoni, Yasser Narknava, Jörn Walter, Bernd Lethaus, Josefin Weber, Victor Carriel, Meltem Avci-Adali, Dorothea Alexander

    Published 2025-04-01
    “…To assess the safety of the generated cells, we evaluated their ability to form teratomas through subcutaneous injection into immunodeficient mice. …”
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    Article
  16. 516

    Soil microbial communities in dry and moist tropical forests exhibit distinct shifts in community composition but not diversity with succession by Kristin Saltonstall, Michiel van Breugel, Wayra Navia, Hilda Castillo, Jefferson S. Hall

    Published 2025-03-01
    “…These patterns were more predictable at the moist than the dry site where the patchiness of the landscape likely restricts dispersal of both plants and soil microbes. …”
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    Article
  17. 517

    Exploring the development and trends of prostate cancer radiotherapy research: a bibliometric analysis by Qinfei Sun, Zhenguo Bu, Shuowei Jiang, Yixin Dai, Yipeng Xu, Jueqi Chen, Yanchi Wang, Lili Zhang

    Published 2025-04-01
    “…Therefore, this study employs bibliometric analysis to evaluate the key research domains, current research landscape, and future development patterns in PC radiotherapy over the last 30 years. …”
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    Article
  18. 518

    Aedes-borne arboviral human infections in Europe from 2000 to 2023: A systematic review and meta-analysis by Nadja Hedrich, Maria Bekker-Nielsen Dunbar, Martin P. Grobusch, Patricia Schlagenhauf

    Published 2025-03-01
    “…Introduction: Aedes-borne arboviral infections, both imported and autochthonous, are reported in Europe. We evaluated the landscape of these infections in Europe over 23 years and attempted to pre-empt the trajectory of impact of these infections in the climatic context of Aedes mosquito expansion in Europe. …”
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    Article
  19. 519

    Integrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma by Hui Peng, Yong-peng Wei, Xin-bo Liu, Yu Wang, Jian-yong Yuan

    Published 2025-09-01
    “…However, its functional significance in shaping the immune landscape and influencing treatment sensitivity in HCC remains insufficiently elucidated. …”
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    Article
  20. 520

    Trends in Real-World Clinical Outcomes of Patients with Anaplastic Lymphoma Kinase (ALK) Rearranged Non-Small Cell Lung Cancer (NSCLC) Receiving One or More ALK Tyrosine Kinase Inh... by Lara Chayab, Natasha B. Leighl, Mina Tadrous, Christine M. Warren, William W. L. Wong

    Published 2024-12-01
    “…The treatment landscape for patients with advanced ALK-positive NSCLC has rapidly evolved following the approval of several ALK TKIs in Canada. …”
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    Article