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501
Analysis of Voice, Speech, and Language Biomarkers of Parkinson’s Disease Collected in a Mixed Reality Setting
Published 2025-04-01“…The findings hold promise for broader clinical applications, advancing the diagnostic landscape for neurodegenerative disorders.…”
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502
Epitranscriptomic analysis reveals clinical and molecular signatures in glioblastoma
Published 2025-04-01“…Novel differences in N6-Methyladenosine (m6A) RNA methylation patterns between these groups are identified in the first biopsy. …”
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503
Integrating metabolism gene clusters and tumor immune microenvironment in head and neck squamous cell carcinoma
Published 2025-06-01“…TNFAIP6 was further evaluated for its functional role through in vitro assays, including proliferation, migration, and invasion analyses. …”
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504
Carbon Emissions From Low‐Order Streams in a Tropical, High‐Elevation, Peatland Ecosystem Are Mediated by Catchment Morphology
Published 2025-04-01“…However, few studies have examined the spatial variability of CO2 concentrations and fluxes occurring within these systems, particularly as a function of catchment morphology. Here we evaluated spatial patterns of CO2 in three tropical, headwater catchments in relation to the river network and stream geomorphology. …”
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505
SmartTrust: a hybrid deep learning framework for real-time threat detection in cloud environments using Zero-Trust Architecture
Published 2025-07-01“…SmartTrust integrates CNN, LSTM, and Transformer models to analyze spatial and temporal patterns in network traffic and user behaviours. Unlike conventional models, it leverages Reinforcement Learning to enable adaptive decision-making, allowing it to adjust responses based on real-time contextual signals dynamically. …”
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506
Vitamin D and MAFLD: a bibliometric and visual analysis from 2007 to 2024
Published 2025-06-01“…R6) and VOSviewer (v1.6.20) software, we evaluated publication trends, regional and national contributions, institutional outputs, journal allocation, author collaborations, reference citations, and keyword patterns.ResultsA total of 480 publications were analyzed, demonstrating a consistent annual increase. …”
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507
Arginine methylation modulates tumor fate and prognosis in clear cell renal cell carcinoma
Published 2025-05-01“…Single-cell RNA sequencing datasets were employed to evaluate gene expression patterns at the cellular level. …”
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508
Global research trends in sarcopenia: a bibliometric analysis of exercise and nutrition (2005–2025)
Published 2025-05-01“…ObjectivesThis study aimed to evaluate the current research landscape, identify emerging areas of interest, and provide scientific insights for further research in exercise and nutrition for sarcopenia.MethodsA comprehensive bibliometric analysis was conducted using publications retrieved from the Web of Science Core Collection and SCOPUS between January 1, 2005 and January 1, 2025, focusing on exercise and nutritional interventions for sarcopenia. …”
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509
Environmental drivers of the resistome across the Baltic Sea
Published 2025-04-01“…The combined effects of salinity and temperature gradients, alongside nutrient availability, created a complex environmental landscape that shaped the diversity and distribution of the predicted ARGs. …”
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510
Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta
Published 2025-03-01“…We characterized X chromosome DNAme variation in the placenta relative to sample variables including cell composition, ancestry, maternal age, placental weight, and fetal birth weight, and compared these patterns to other tissues. We also evaluated the relationship between X-linked DNAme and previously reported XCI gene expression status in placenta. …”
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511
A Chemotherapy Response-Related Gene Signature and DNAJC8 as Key Mediators of Hepatocellular Carcinoma Progression and Drug Resistance
Published 2025-03-01“…We constructed a prognostic model using Least Absolute Shrinkage and Selection Operator (LASSO) analysis and assessed its efficacy using Kaplan-Meier survival analysis. Additionally, we evaluated the immune landscape and gene mutation profiles between different chemotherapy response-related gene (CRRG) subtypes. …”
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512
Virtual Avebury: exploring sense of place in a virtual archaeology simulation
Published 2020-07-01“…This paper describes and discusses creating and evaluating a virtual reality simulation of Avebury Stone Circle and Henge complex as it might have appeared and sounded circa 2300 BCE. …”
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513
VPS26A as a Prognostic Biomarker and Therapeutic Target in Liver Hepatocellular Carcinoma: Insights from Comprehensive Bioinformatics Analysis
Published 2025-07-01“…<i>Materials and Methods:</i> Multiple databases, including TIMER, UALCAN, HPA, GSCA, KM Plotter, OSlihc, MethSurv, miRNet, OncomiR, LinkedOmics, GeneMANIA, and STRING, were used to evaluate VPS26A expression patterns, prognostic implications, correlations with tumor-infiltrating immune cells (TIICs), epigenetic modifications, drug sensitivity, co-expression networks, and protein–protein interactions in LIHC. …”
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514
Inspiring Social Capital Through Community Green Space: Pathways and Implications
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515
Revitalizing the Epigenome of Adult Jaw Periosteal Cells: Enhancing Diversity in iPSC-Derived Mesenchymal Stem Cells (iMSCs)
Published 2025-04-01“…To assess the safety of the generated cells, we evaluated their ability to form teratomas through subcutaneous injection into immunodeficient mice. …”
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516
Soil microbial communities in dry and moist tropical forests exhibit distinct shifts in community composition but not diversity with succession
Published 2025-03-01“…These patterns were more predictable at the moist than the dry site where the patchiness of the landscape likely restricts dispersal of both plants and soil microbes. …”
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517
Exploring the development and trends of prostate cancer radiotherapy research: a bibliometric analysis
Published 2025-04-01“…Therefore, this study employs bibliometric analysis to evaluate the key research domains, current research landscape, and future development patterns in PC radiotherapy over the last 30 years. …”
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518
Aedes-borne arboviral human infections in Europe from 2000 to 2023: A systematic review and meta-analysis
Published 2025-03-01“…Introduction: Aedes-borne arboviral infections, both imported and autochthonous, are reported in Europe. We evaluated the landscape of these infections in Europe over 23 years and attempted to pre-empt the trajectory of impact of these infections in the climatic context of Aedes mosquito expansion in Europe. …”
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519
Integrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma
Published 2025-09-01“…However, its functional significance in shaping the immune landscape and influencing treatment sensitivity in HCC remains insufficiently elucidated. …”
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520
Trends in Real-World Clinical Outcomes of Patients with Anaplastic Lymphoma Kinase (ALK) Rearranged Non-Small Cell Lung Cancer (NSCLC) Receiving One or More ALK Tyrosine Kinase Inh...
Published 2024-12-01“…The treatment landscape for patients with advanced ALK-positive NSCLC has rapidly evolved following the approval of several ALK TKIs in Canada. …”
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