Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders (ERI-SIBS): a controlled trial of an innovative and ecological intervention for siblings... by Silvia Annunziata, Giulia Purpura, Giulia Purpura, Elena Piazza, Paolo Meriggi, Gabriele Fassina, Laura Santos, Emilia Ambrosini, Antonella Marchetti, Antonella Marchetti, Federico Manzi, Federico Manzi, Davide Massaro, Davide Massaro, Andrea Luna Tacci, Andrea Luna Tacci, Elisabetta Bolognesi, Simone Agostini, Francesca La Rosa, Alessandra Paola Giulia Pedrocchi, Paola Molina, Anna Cavallini

“…In response to this, early recognition protocols have been developed worldwide, aiming to promote early interventions that can positively impact the neurodevelopment of this population. This paper presents the protocol of a controlled trial: ERI-SIBS (Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders) is an innovative and ecological early recognition and intervention program designed specifically for siblings of children with ASD.MethodsWe aim to recruit siblings at low risk and high risk of neurodevelopmental disorders. …”
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EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures by María Victoria Villar, Katerina Cernochova, Jaime Cuevas, Antonio Gens, Natalia Gimeno, Caroline Graham, Jon Harrington, Vlastislav Kašpar, Stephan Kaufhold, Olivier Leupin, David Mašín, Jan Najser, Markus Olin, Heini Reijonen, Šárka Šachlová, Sergey Sayenko, Daniel Svensson, Jiri Svoboda, Gianni Vettese, Janne Yliharju, Borys Zlobenko

“…A synthesis of the state of knowledge on the thermo-hydro-mechanical and chemical behaviours of different buffer materials at different temperatures is presented, along with the progress made in this area during HITEC. …”
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Cardiovascular toxicities in cancer patients treated with immune checkpoint inhibitors: multicenter study using natural language processing on Belgian hospital data by D. Delombaerde, C.L. Oeste, V. Geldhof, L. Croes, I. Bassez, A. Verbiest, L. Tack, D. Hens, C. Franssen, P.R. Debruyne, H. Prenen, M. Peeters, J. De Sutter, C. Vulsteke

“…Hence, clinicians should note that CV AEs can present in various ways and at any time during or after treatment.…”
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FitSkills: protocol for a stepped wedge cluster randomised trial of a community-based exercise programme to increase participation among young people with disability by Nicholas F Taylor, Nora Shields, Andrea M Bruder, Claire Willis, Christine Imms, Luke A Prendergast, Jennifer J Watts, Ben van Dorsselaer, Georgia McKenzie, Luke Prendergast, Jason Calleja, David Strickland, Shawn Stephenson, Michael P Walker, Justine Robbins, Melissa Barkley, Cameron Geddes, Shane Lee, Richard Amon, Juliet Ryan, Ayden Shaw, Simone Power, Rebecca McCabe, Shannon Cheal, Vicki Cavelieros, Debby Fraumano, Sue Blandford, Lucy Bain, Sonia Bonadio, Sue O’Riley, Bernadette Roberts, John Summers, Troy Walker, Fiona Kriaris, Sam Taylor, Tom Scanlan, Abigail Elliot, Lachlan O’Brien, Jenni Smith, Stacey Cleary, Brooke Adair, Melissa Moore, Jess Kuek

“…Results will be disseminated through published manuscripts, conference presentations, public seminars and practical resources for stakeholder groups.Trial registration number ACTRN12617000766314.Trial sponsor La Trobe University.…”
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A workflow of open-source tools for drone-based photogrammetry of marine megafauna by K.C. Bierlich, Josh Hewitt, Clara N. Bird, David W. Johnston, Julian Dale, Enrico Pirotta, Robert S. Schick, Joshua D. Stewart, Leslie New, Elliott Chimienti, Jeremy A. Goldbogen, Ari S. Friedlaender, Mauricio Cantor, Leigh G. Torres

“…Workflows containing free, open-source tools and methods that are accommodating to various research budgets and types of drones (consumer vs. professional) are more inclusive and equitable, which will foster increased knowledge in ecology and wildlife science. Here we present a workflow for collecting, processing, and analyzing morphological measurements of megafauna using drone-based photogrammetry. …”
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Isolated Aortic Valve Replacement: Early Results from a 16-Year Experience by Selman Dumani, Ermal Likaj, Saimir Kuci, Laureta Dibra, Fjorba Mana, Devis Pellumbi, Alfred Ibrahimi, Stavri Llazo, Edlira Rruci, Ervin Bejko, Aferdita Veseli, Andi Kacani, Edvin Prifti, Klodian Krakulli, Ali Refatllari, Alessia Mehmeti, Fatjon Hamiti, Elizana Petrela, Altin Veshti

“…These findings contribute to the growing body of knowledge in cardiac surgery, providing valuable insights for future research and practice. …”
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Regional and sub-regional estimates of low birth weight and its determinants in 44 low- and middle-income countries: evidence from demographic and health survey data by Kusse Urmale Mare, Gashaye Gobena Andarge, Kebede Gemeda Sabo, Osman Ahmed Mohammed, Ahmed Adem Mohammed, Abdulkerim Hassen Moloro, Oumer Abdulkadir Ebrahim, Beminate Lemma Seifu, Bizunesh Fantahun Kase, Habtamu Solomon Demeke, Temesgen Gebeyehu Wondmeneh, Setognal Birara Aychiluhm, Abay Woday Tadesse, Getahun Fentaw Mulaw, Simeon Meskele Leyto, Begetayinoral Kussia Lahole, Tesfahun Simon Hadaro, Beriso Furo Wengoro

“…Overall and sub-regional trends in low birth weight estimates were presented using a line graph. A multilevel mixed-effect analysis was done to identify determinants of low birth weight. …”
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Genomic surveillance indicates high site-specific heterogeneity of West Nile virus in mosquitoes in rural regions of Germany across seasons by Corinna Patzina-Mehling, Anne Kopp, Leif Rauhöft, Tatiana Șuleșco, Terry C. Jones, Christian Drosten, Felix Gregor Sauer, Renke Lühken, Sandra Junglen

“…However, there is little knowledge on WNV dispersal and maintenance on a small spatial scale. …”
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Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa [version 2; peer review: 2 approved,... by Robert J Wilkinson, Francisco Lakay, Nicki Tiffin, Joel A Dave, Catherine Riou, Peter Raubenheimer, Anna K Coussens, Tsaone Tamuhla, Melissa J Blumenthal, Maleeka Abrahams

“…Background There is limited knowledge regarding African genetic drivers of disease due to prohibitive costs of large-scale genomic research in Africa. …”
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The variation of coverage and access to palliative care for cancer patients in eight European countries: an exploratory vignette approach by Nathan Shuftan, Mark Dayan, Sarah Scobie, Bee Wee, Antoniya Dimova, Elka Atanasova, Liubove Murauskiene, Coralie Gandré, Zeynep Or, Gonçalo Figueiredo Augusto, Triin Habicht, Kristina Köhler, Kristiina Kahur, Bertil Axelsson, Madelon Kroneman, Judith de Jong, Anke de Veer, Wanda Bemelmans, Chantal Pereira, Ajay Aggarwal, Joanna Davies, Ewout van Ginneken, Dimitra Panteli

“…Organizational barriers, societal stigmas and knowledge gaps about what palliative care entails were also found to be areas in need of improvement. …”
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3D virtual reconstruction of the Gauzón Castle (Castrillón, Principado de Asturias) by Pablo Aparicio-Resco, Alejandro García Álvarez-Busto, Iván Muñiz-López, Noelia Fernández-Calderón

“…Furthermore, the result presented here demonstrates the power of this graphic resource for the dissemination of historical-archaeological knowledge, a fundamental objective when carrying out any scientific work. …”
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Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis-2 (AuToDeCRA-2) study: protocol for a single-centre, experimental medicine study investigating the route of delivery... by Ema-Louise Long, James Stanway, Michael White, Nicola Goudie, Julia Phillipson, Miranda Morton, Asma Abdul Malek, Philip Brown, Geoff Hide, Ralph Jackson, Colin Nice, John Tuckett, Julie Diboll, Amy Anderson, Arthur Pratt, Catharien M. U. Hilkens, John Isaacs

“…Abstract Background Dendritic cells are professional antigen presenting cells with the ability, in their immature state, to induce tolerance in T cells. …”
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Bibliometric analysis of research trends in agricultural soil organic carbon components from 2000 to 2023 by Guolong Ge, Xuanyi Chen, Hexiao Ma, Xiangqian Zhang, Xiangqian Zhang, Jingjing Shi, Xiaoxiang Wang, Xiaoqing Zhao, Xiaoqing Zhao, Manxiu Wang, Feng Xian, Zhanyuan Lu, Zhanyuan Lu, Zhanyuan Lu, Yuchen Cheng, Yuchen Cheng

“…However, the mechanism of soil organic carbon sequestration and response characteristics of soil organic carbon components to soil carbon pools are still subject to some debate. To the best of our knowledge, no researchers have used bibliometric analyses to explore the field of soil organic carbon components. …”
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Local QSAR based on quantum chemistry calculations for the stability of nitrenium ions to reduce false positive outcomes from standard QSAR systems for the mutagenicity of primary... by Shigeharu Muto, Ayako Furuhama, Mika Yamamoto, Yasuteru Otagiri, Naoki Koyama, Seiji Hitaoka, Yusuke Nagato, Hirofumi Ouchi, Masahiro Ogawa, Kisako Shikano, Katsuya Yamada, Satoshi Ono, Minami Hoki, Fumiya Ishizuka, Soichiro Hagio, Chiaki Takeshita, Hisayoshi Omori, Kiyohiro Hashimoto, Satsuki Chikura, Masamitsu Honma, Kei-ichi Sugiyama, Masayuki Mishima

“…Abstract Background Primary aromatic amines (PAAs) present significant challenges in the prediction of mutagenicity using current standard quantitative structure activity relationship (QSAR) systems, which are knowledge-based and statistics-based, because of their low positive prediction values (PPVs). …”
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Regional and aging-specific cellular architecture of non-human primate brains by Yun-Mei Wang, Wen-Chao Wang, Yongzhang Pan, Lin Zeng, Jing Wu, Zheng-Bo Wang, Xiao-Lin Zhuang, Ming-Li Li, David N. Cooper, Sheng Wang, Yong Shao, Li-Min Wang, Ying-Yin Fan, Yonghan He, Xin-Tian Hu, Dong-Dong Wu

“…These datasets greatly expand our knowledge of primate brain organization and highlight the potential involvement of specific molecular and cellular components in both the regionalization and functional integrity of the brain. …”
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Candidate Phyla Radiation (CPR) bacteria from hyperalkaline ecosystems provide novel insight into their symbiotic lifestyle and ecological implications by Yu He, Shiyan Zhuo, Meng Li, Jie Pan, Yongguang Jiang, Yidan Hu, Robert A. Sanford, Qin Lin, Weimin Sun, Na Wei, Shuming Peng, Zhou Jiang, Shuyi Li, Yongzhe Li, Yiran Dong, Liang Shi

“…Although CPR bacteria have been identified in varied environments, their broader distribution, associations with hosts, and ecological roles remain largely unexplored. To address these knowledge gaps, a serpentinite-like environment was selected as a simplified model system to investigate the CPR communities in hyperalkaline environments and their association with hosts in extreme conditions. …”
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Mechanized Transplanting Improves Yield and Reduces <i>Pyricularia oryzae</i> Incidence of Paddies in Calasparra Rice of Origin in Spain by María Jesús Pascual-Villalobos, María Martínez, Sergio López, María Pilar Hellín, Nuria López, José Sáez, María del Mar Guerrero, Pedro Guirao

“…The most-affected sowing plots presented 3–20% leaf area damage and a reduction in yield to values of 1.5 t ha⁻¹ in the first year and 2.12 t ha⁻¹ in the second year. …”
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A co-created self-care and informal support intervention targeting women with gestational diabetes mellitus in northern Vietnam (VALID-II): a protocol for a two-arm non-randomised... by Ditte S. Linde, Hieu M. Le, Dung T. K. Vu, Ngoc-Anh T. Dang, Ai T. Nguyen, Tuc P. Vu, Xuan-Bai Nguyen, Cuong D. Nguyen, Dan W. Meyrowitsch, Jens Søndergaard, Christina A. Vinter, Ib C. Bygbjerg, Vibeke Rasch, Thanh D. Nguyen, Tine M. Gammeltoft, Dang K. Nguyen

“…Abstract Background Gestational diabetes mellitus (GDM) is a transitory form of diabetes that presents during pregnancy with frequent adverse maternal and neonatal health consequences if left untreated. …”
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Enhancing cognitive function in breast cancer survivors through community-based aerobic exercise training: protocol for a Hybrid Type I effectiveness–implementation study employing... by Paul Estabrooks, Jessica D Austin, Brenda Ernst, Diane K Ehlers, Lindsey L Page, Edward Ofori, Gwenndolyn C Porter, Jason Fanning, Gabriella Hickman, Paul McKim, Melissa Cole, Maliyah Donaldson, B Blair Braden, Katie L Kunze, Richard J Butterfield, Leslie C Baxter, Tim A Ahles

“…Findings will be disseminated to scientific, clinical and community audiences through manuscripts, presentations and newsletters.Trial registration number NCT04816006.…”
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Determinants of Caregivers’ Ability to Accurately Detect Acute Malnutrition Using Color-Coded Mid-Upper Arm Circumference Tape and Pitting Edema by Benson C Singano, Collina A Tchongwe, Numeri C Geresomo, Tinna Ng’ong’ola-Manani, Aaron T Chikakuda, Alfred Ngwira, Stanley Mwase, Elsie Mawala, Benson Kazembe, Emma Budalla, Alexander A Kalimbira

“…More data and further studies are required to validate the present results.…”
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