Multifactorial Control of Autoimmune Insulin-Dependent Diabetes in NOD Mice: Lessons for IBD by Edward H Leiter

“…Genetic susceptibility is transmitted by hemopoietic stem cells, and specific defects in T immunoregulation have been traced to defects in the development and function of marrow-derived antigen presenting cells. …”
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Modulation of Sel1L can alleviate altered ER homeostasis towards white matter damage in CKD-stroke complex by Aishika Datta, Priti Patale, Debarati Ghosh, Priya Jagtap, Jinagna Shah, Mounika Katamneni, Anita Kumari, Nikita Malik, Gautam Karmarkar, Anirban Barik, Bijoyani Ghosh, Pooja Dhakne, Vinod Pathulothu, Deepaneeta Sarmah, Harpreet Kaur, Nikita Rana, Rajeshwari Rathod, Anupom Borah, Pinaki Sengupta, Pallab Bhattacharya

“…Abstract Stroke is one of the major causes of mortality and long-term disability worldwide. Chronic-kidney-disease (CKD) is a condition where patients have shown increased vulnerability to stroke with poor functional and cognitive outcomes. …”
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Health status biomarkers and hemato-biochemical indices in Nile tilápia by Lorena Bavia, Ana Paula da Silva, Milena Carvalho Carneiro, Melyssa Kmecick, Roberta Pozzan, Juan Esquivel-Muelbert, Lourdes Isaac, Maritana Mela Prodocimo

“…Thus, our aim is to establish reference values for Nile tilapia for comparative purposes for: (i) functional activation of the alternative pathway of the complement system (ACH50), (ii) some serum biochemical parameters of liver, kidney and muscle tissue integrity, and (iii) hematological profile of Nile tilapia under controlled conditions. …”
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(R)-NODAGA-PSMA: A Versatile Precursor for Radiometal Labeling and Nuclear Imaging of PSMA-Positive Tumors. by Eleni Gourni, Coline Canovas, Victor Goncalves, Franck Denat, Philipp T Meyer, Helmut R Maecke

“…The acquisition of PET-images with 64Cu-CC34 at later time points showed wash-out from the kidneys, while tumor uptake still remained relatively high. …”
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Preclinic evaluation of the safety of potential anticovid-19 phytomedicine: SAYE PLUS impacts on Wistar rat biochemical and histopathological parameters in sub-chronic toxicity stu... by Joël Ouédraogo, Sylvain Ilboudo, Geoffroy Gueswindé Ouédraogo, Gaétan Donzèo Somda, Barthélemy Bonogo, Virginie Dakuyo, Salfo Ouédraogo, Raïnatou Boly, Mathieu Nitiéma, Dofini Réné Magnini, Rasmané Semdé, Sylvin Ouédraogo

“…Further long-term studies focusing on the hematological parameters and certain kidney and liver functional indicators will add the scientific merit and interest of the present work.…”
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Exploring the shared molecular mechanisms of primary hypertension and IgA vasculitis through a case report and combining bioinformatics analysis by Qijiao Wei, Jiayan Feng, Yifei Mu, Qian Shen, Hong Xu, Li Sun, Haimei Liu

“…DEGs were analyzed, and gene functional enrichment was performed using the DAVID database. …”
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Our experience with management of congenital urological pathologies in adulthood: What pediatric urologists should know and adult urologists adopt in pediatric practice experience by Leon Chertin, Binyamin B. Neeman, Jawdat Jaber, Guy Verhovsky, Amnon Zisman, Ariel Mamber, Ilan Kafka, Ala Eddin Natsheh, Dmitry Koulikov, Ofer Z. Shenfeld, Boris Chertin, Stanislav Koucherov, Amos Neheman

“…To summarize our experience in the management of congenital anomalies in the kidney and urinary tract (CAKUT) in adults. Materials and methods. …”
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Case of acute drug-induced hepatitis after halothane anesthesia by I. Yu. Pirogova, Ye. V. Berestova, O. Yu. Bastrikov, Ye. B. Kovaleva, T. P. Petukhova, M. V. Guseva, I. A. Gubina, I. V. Rezepin, S. P. Sinitsyn

“…Biotransformation of volatile anesthetics can result in production of toxic metabolites and metabolic by-products, resulting in damage of the liver and kidneys. Disorders of liver function can be of two types: early – transient elevation of transaminase activity and late – liver necrosis. …”
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Severe Uncompensated Metabolic Alkalosis due to Plasma Exchange in a Patient with Pulmonary-Renal Syndrome: A Clinician’s Challenge by Mohsin Ijaz, Naeem Abbas, Dmitry Lvovsky

“…Citrate metabolism generates bicarbonate and once its level exceeds the excretory capacity of kidneys, the severe metabolic alkalosis ensues. Our patient presented with generalized weakness, fever, and oliguria and developed rapidly progressive renal failure. …”
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Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates by Leonardo Traini, Javier Negueruela, Bernat Elvira, Wadsen St-Pierre-Wijckmans, Valerie Vandenbempt, Carlos E. Buss, Ao Li, Israel Pérez-Chávez, Francisco Ribeiro-Costa, Mariana Nunes, Joris Messens, Daria Ezeriņa, David C. Hay, Mayank Bansal, Esteban N. Gurzov

“…The maturation and functionality TXNIP −/− and TXNIP +/+ SC-islets were assessed by implantation under the kidney capsule of male or female NOD-SCID mice. …”
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Association between malnutrition determined by hand grip strength and the presence of minimal hepatic encephalopathy in women with liver cirrhosis by Valeria Rangel-Espinosa, Marlene López-Sánchez, Aldo Allende-López, Nayeli Ortiz-Olvera, Aleida Bautista-Santos, Rosalba Moreno-Alcántar, Segundo Morán

“…Hand grip strength (HGS) serves as a marker of muscle functionality; however, the relationship between HGS values and the presence of MHE remains uncertain. …”
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Clinical manifestations of COVID-19 infection and its impact on the outcome in children and adolescents with benign and malignant hematological disease in Egypt: a single-center ex... by Fatma Soliman Elsayed Ebeid, Aya Mostafa, Sondos M. Magdy, Haidy Moahmed Abd El Kader, Amal Abdel Azim Lotfy, Nihal Hussien Aly

“…Baseline laboratory investigation were collected included complete blood count (CBC), liver and kidney functions, C-reactive protein (CRP), serum ferritin, lactate dehydrogenase, and coagulation test. …”
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The effect of herbal supplements on development of internal organs and chemical composition of broilers muscles by A. I. Nufer, E. V. Shatskikh

“…The present article presents data on effectiveness of adding a phytobiotic feed additive into the diet of broiler chickens, either additionally or replacing the feed antibiotic in the chicken fodder. …”
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Psychogenic diabetes insipidus: A case report of behaviour psychotherapy by Stanković Miodrag M., Stevanović Jelena, Stojanović Aleksandra, Stanković Sandra

“…Psychogenic diabetes insipidus is potentially a life-threating condition manifesting as a psychogenic thirst disorder with excessive fluid intake (more than 3 L per day) and a preserved function of neurohypophysis and kidneys. Case report. …”
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CD28 Family and Chronic Rejection: “To Belatacept...and Beyond!” by Marcos V. Silva, Juliana R. Machado, Laura P. Rocha, Lúcio R. Castellano, Marlene A. Reis, Rosana R. M. Corrêa

“…Kidneys are one of the most frequently transplanted human organs. …”
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Multiomics approach provides insight into altered choline metabolism and liver injury in patients with glycogen storage disease type Ia by Francesca Pirozzi, Ramin Amiri, Camilla Luni, Alessandro Rossi, Daniela Melis, Roberta Fedele, Carmen Rosano, Pietro Strisciuglio, Maaike H. Oosterveer, Terry G. J. Derks, Giancarlo Parenti, Marianna Caterino, Margherita Ruoppolo

“…Abstract Glycogen storage disease type Ia (GSDIa) is an inherited disorder of carbohydrate metabolism. Patients present with excessive storage of glycogen and fat in the liver and kidneys and are potentially at risk of developing long-term complications. …”
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It’s a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies by Johanna Trommer, Martin Ullrich, Falco Reissig, Santiago Andres Brühlmann, Anne-Kathrin Nitt-Weber, Zbynek Novy, Katarina Hajduova, Daniela Kurfurstova, Romana Hendrychova, Jan Bouchal, Milos Petrik, Christin Neuber, Wiebke Sihver, Sven Stadlbauer, Jens Pietzsch, Martin Kreller, Klaus Kopka, Constantin Mamat, Kristof Zarschler

“…Conclusions We present a comprehensive study on the theranostic application of 133La and 225Ac for antibody-based biomolecules and lay the foundation for the future application of this matched pair of radionuclides towards labeling of heat-sensitive, macropa-functionalized radiopharmaceuticals in general.…”
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Impact of Psychosocial Factors on Quality of Life: A Case Study of End Stage Renal Disease by Iqra Nazar, Dr. Fatima Kamran, Dr. Rafia Rafique, Dr. Ghulam Ishaq

“… End-stage renal disease (ESRD) occurs when kidneys gradually lost its function. In Pakistan, the prevalence of ESRD is 37.9% of the adult population overall. …”
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Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation by Yuanyuan He, Miaosen Wang, Miao An, Md. F. Kulyar, Ming Li, Huifen Xu, Yaping Wang

“…Therefore, we aimed to explore the adverse effects and mechanisms of lead exposure in pregnant mice on the next generation. The present study indicated that lead exposure decreased growth performance and impaired the function of the colon, spleen, testes, and kidneys in the next generation of mice. …”
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Case Report: Rescue “awake” extracorporeal membrane oxygenation for acute respiratory failure in severe granulomatosis with polyangiitis with multisystem involvement by Taehun Kim, Byung Wook Song, Hyeong Chan Shin

“…We present the case of a 40-year-old man who developed severe acute respiratory failure along with hemoptysis and was subsequently diagnosed with granulomatosis with polyangiitis (GPA). …”
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