Biological and technological evaluation of sidr (Ziziphus spina Christi L.) based on high fat diet as antihyperlipidemic effects by Heba, A. Barakat, Dina, M. Sabri, Akram, M. M. Elanany, Amany, A. Salem

“…The rats in group 3, which fed on a high-fat diet with 10% sidr pulp powder, had improved blood lipid profile compared with hyperlipidemic rats in other groups. The same thing for kidney and liver functions was improved in hyperlipidemic rats feeding on 10% sidr pulp powder in their diet. …”
Get full text

Prostaglandins - universal biological regulators in the human body (literature review) by О. V. Tymoshchuk, І. S. Lembryk, Z. R. Кocherga

“…Prostaglandins have an extremely wide range of physiological effects in the body and have three main functions: supporting, molecular, neurotransmitter. …”
Get full text

Testosterone-induced erythrocytosis: addressing the challenge of metabolic syndrome and widely prescribed SGLT2-inhibitor drugs by Federica Tramontana, Azmi Mohammed, Yaasir H Mamoojee, Richard Quinton

“…Testosterone is now increasingly prescribed to older men with functional hypogonadism and obesity, hypertension or type 2 diabetes, who are anyway at higher risk of both erythrocytosis and thrombosis. …”
Get full text

Biological Efficacy and Toxicological Evaluation of Ethanolic Extract of Cassia nodosa Buch.-Ham. (Leguminosae) by Gameli Afu, Michael Konney Laryea, Lawrence Sheringham Borquaye

“…The extract was also evaluated for acute oral toxicity and its toxicity to the liver and kidney of rats. Phytochemicals present in the extract included sterols, alkaloids, tannins, glycosides, and coumarins. …”
Get full text

Infectious complications as predictors of adverse outcome in a patient with systemic lupus erythematosus (clinical case) by N. M. Nikitina, O. L. Aleksandrova, Ye. N. Skryabina, N. A. Magdeeva

“…An adverse outcome may occur because of kidney damage, damage of the nervous system, severe hematological disorders, etc. …”
Get full text

Current views on antiplatelet therapy in acute coronary syndrome patients: the place of clopidogrel by O. O. Shakhmatova

“…The article discusses approaches to forced de-escalation of antiplatelet therapy – switching from a more potent P2Y12 receptor blocker to clopidogrel. Data is also presented on the study of routine de-escalation at the end of the acute ACS period, both empirical and controlled by functional or genetic tests characterizing the efficacy of clopidogrel. …”
Get full text

Talinum trangulare (Waterleaf) Stem Extract Has Reno-Hepato Protective Potentials than Ameliorative Effects on Acetaminophen Toxicity in Sprague-Dawley Rats by Theophilus Ogie Erameh1,2, Ifueko Mercy Moses-Otutu1, Anthony Chukwuemeka Nwaobi2, Efosa Bolaji Odigie1*, Blessing Eshovo Akpeji1 and Ramatu Yahaya2

“…Blood sample was collected through cardiac puncture to determine kidney and liver functions while related organs were processed histologically. …”
Get full text

Advances in Biosensor Applications of Metal/Metal-Oxide Nanoscale Materials by Md Abdus Subhan, Newton Neogi, Kristi Priya Choudhury, Mohammed M. Rahman

“…Through direct and indirect labeling, metal-oxide NPs are extensively employed in detecting metabolic disorders, such as cancer, diabetes, and kidney-disease biomarkers based on electrochemical, optical, and magnetic readouts. …”
Get full text

Optimization of food compositions according to the ideal protein profile by S. V. Zverev, V. I. Karpov, M. A. Nikitina

“…Plant components (white kidney beans, flax, peanut, grit “Poltavskaya», dry red carrot) were used as an object of the research. …”
Get full text

Circulating Factors as Potential Biomarkers of Cardiovascular Damage Progression Associated with Type 2 Diabetes by Giovanni Sartore, Francesco Piarulli, Eugenio Ragazzi, Alice Mallia, Stefania Ghilardi, Massimo Carollo, Annunziata Lapolla, Cristina Banfi

Get full text

Advancements in minimally invasive interventional oncology procedures for painful sacral metastases under imaging guidance by Will Jiang, Donghao Gan, Michele H. Johnson, Igor Latich, Francis Y. Lee

“…Objective: To examine percutaneous interventions for sacral metastases and present advancements in intra-operative imaging guidance. …”
Get full text

Post-translational modifications of collagen and its related diseases in metabolic pathways by Linghong Guo, Weiyi Xiang, Zhaoping Pan, He Gu, Xian Jiang

“…As the most abundant and essential structural protein in the human body, collagen is ubiquitously present in the interstitium of nearly all solid organs, playing a crucial role in maintaining the structural integrity and functional stability of human tissues and organs. …”
Get full text

In vitro anticancer and antifungal effects of Lactobacillus paracasei supernatants: a step toward sustainable food systems by Berna Erdal, Bahar Yilmaz, Esra Bozgeyik, Seydi Yıkmış, Isam A. Mohamed Ahmed, Moneera O. Aljobair, Monica Trif

“…This study investigates both the anticancer and antifungal properties of live and thermally inactivated cell-free supernatants (CFSs) of Lactobacillus paracasei subsp. paracasei, a food-grade probiotic, thereby addressing a significant research gap in the dual-functional potential of probiotic metabolites. Human glioma (U-87) and non-cancerous kidney epithelial (HEK293T) cells were treated with live and inactivated CFSs. …”
Get full text

Gamma-glutamyl transpeptidase is a promising biological marker of heart failure by A. M. Alieva, I. E.  Baykova, K.  V. Voronkova, N. V. Teplova, L.  M.  Shnakhova, R.  K.  Valiev, D. A. Elmurzaeva, A. M. Rakhaev, M. R.  Kalova, I.  G. Nikitin

“…There is a significant variability in enzyme activity, which is especially high in tissues with a secretory and absorptive function, such as the kidneys, biliary tract, intestines, and epididymis.Purpose of the review is to present an overview of current publications devoted to the study of γ-glutamyl transpeptidase in the aspect of a biological marker of heart failure.Materials and methods. …”
Get full text

Advances in humanoid organoid-based research on inter-organ communications during cardiac organogenesis and cardiovascular diseases by Baoqiang Ni, Lingqun Ye, Yan Zhang, Shijun Hu, Wei Lei

“…Abstract The intimate correlation between cardiovascular diseases and other organ pathologies, such as metabolic and kidney diseases, underscores the intricate interactions among these organs. …”
Get full text

Prevention of Renal Injury After Induction of Ozone Tolerance in Rats Submitted to Warm Ischaemia by E. Barber, S. Menéndez, O. S. León, M. O. Barber, N. Merino, J. L. Calunga, E. Cruz, V. Bocci

“…Morphological alterations of the kidney were present in 100%, 88% and 30% of the animals in groups 2, 4 and 3, respectively. …”
Get full text

An integrated alarm with clamp system to mitigate vascular access bleeding in hemodialysis: a prospective cohort mixed methods study by Ryan J. Chan, Margaret McGrath-Chong, Christopher T. M. Chan

“…Abstract Establishing and maintaining a functional vascular access is essential for patients with end-stage kidney disease on home hemodialysis. …”
Get full text

High mobility group box 1 (HMGB1) mediates nicotine-induced podocyte injury by Sayantap Datta, Mohammad Atiqur Rahman, Saisudha Koka, Krishna M. Boini

“…High mobility group box 1(HMGB1) is a highly conserved non-histone chromatin associated protein that largely contributes to the pathogenesis of chronic inflammatory and autoimmune diseases such as sepsis, atherosclerosis, and chronic kidney diseases. Hence, the present study tested whether HMGB1 contributes to nicotine-induced podocyte injury.Methods and ResultsBiochemical analysis showed that nicotine treatment significantly increased the HMGB1 expression and release compared to vehicle treated podocytes. …”
Get full text

Therapeutic agents for machine perfusion of donor organs by O. N. Rzhevskaya, V. M. Magilevets, R. S. Islamgazin, B. I. Yaremin, E. Yu. Anosova, A.  G. Balkarov, M. S. Novruzbekov

“…The literature presents novel technologies of ex vivo and in vivo machine perfusion of donor organs, which make it possible to improve their functions and perform a successful transplant. …”
Get full text

Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats by Quiñonez-Bastidas Geovanna Nallely, Osuna-Martínez Ulises, Reda-Licea Ana Laura, López-Ortíz Manuel, Regla Ignacio, Navarrete Andrés

“…On the other hand, changes in renal and hepatic functions were not observed. Likewise, analysis of liver, kidney and heart histology showed no alterations compared with controls. …”
Get full text