Preventing Proximal Femur Pathologic Fractures Improves Outcomes in Patients with Metastatic Bone Disease: A Clinical Study Based on a Single Center Experience by Joana Páscoa Pinheiro, Mariana Nabais, André Spranger, Paulo Almeida, José Portela, Joaquim Soares do Brito

“…Nine patients had lung cancer metastases, eight had breast cancer metastases, seven had prostatic cancer secondary lesions, four presented uterine cancer secondary lesions, three cases were secondary to kidney cancer, and six patients had MM lesions. …”
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A polymeric dexamethasone prodrug attenuates focal segmental glomerulosclerosis (FSGS) in an Adriamycin-induced mouse model with minimal glucocorticoid side effects by Haochen Jiang, Xin Fu, Salma Althobaiti, Braeden Pinkerton, Shabnam Arash, Xiaoqing Du, Zhenshan Jia, Fang Yu, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang

“…A single dose of PEG-Dex treatment (35 ​mg/kg Dex dose equivalent) effectively reduced the proteinuria level, ameliorated FSGS lesions and restored kidney function when compared to the dose equivalent daily Dex treatment and Saline control. …”
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Grass carp Trim47 restricts GCRV infection via SPRY domain-mediated autophagic degradation of nonstructural proteins and disruption of viral inclusion bodies by Wei Yan, Wei Yan, Yang Chen, Yang Chen, Dong Yan, Dong Yan, Jie Zhang, Jie Zhang, Ming Xian Chang, Ming Xian Chang

“…This strategy mitigated splenic/kidney viral loads and alleviated histopathological damage, including tubular necrosis and inflammatory infiltration. …”
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Clinical consequences of psychoemotional stress in adolescence by Л.А. Страшок, Л.І. Рак, А.В. Єщенко, В.Л. Кашіна-Ярмак, Е.М. Завеля, М.Ю. Ісакова

“…Attention is focused on the formation of cardiovascular pathology, including life-threatening conditions, on disorders of various parts of the gastrointestinal tract and the gut microbiome, changes in kidney and urinary system function. The article provides up-to-date information on the manifestations of endocrine diseases, disorders of autonomic regulation and immune homeostasis under the influence of psychoemotional stress. …”
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Anthelmintic activity of winter savory (Satureja montana L.) essential oil against gastrointestinal nematodes of sheep by Filip Štrbac, Slobodan Krnjajić, Radomir Ratajac, Laura Rinaldi, Vincenzo Musella, Fabio Castagna, Dragica Stojanović, Nataša Simin, Dejan Orčić, Antonio Bosco

“…No toxic effects were observed, either in the physical observation of the test animals or in their liver and kidney function. No significant changes (p > 0.05) in the percentage representation of GIN genera were observed in the coproculture study, indicating that the treatment agent was not specific to a single genus. …”
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PM_2.5 Exposure Induces Glomerular Hyperfiltration in Mice in a Gender-Dependent Manner by Hao Wang, Li Ma, Yuqiong Guo, Lingyu Ren, Guangke Li, Nan Sang

“…Examination of renal function indices, including creatinine (CRE), blood urea nitrogen (BUN), uric acid (UA), and urinary microalbumin, indicated that the kidneys of female mice, not male mice, underwent early renal injury, exhibiting glomerular hyperfiltration. …”
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Insights into the protective effect of omega-3 nanoemulsion against colistin-induced nephrotoxicity in experimental rats: regulation of autophagy and necroptosis via AMPK/mTOR and... by Medhat Taha, Omer Abdelbagi, Tourki A. S. Baokbah, Rehab M. Bagadood, Naif A. Jalal, Rami Obaid, Nawal E. Al-Hazmi, Naeem F. Qusty

“…The results revealed that colistin administration caused deterioration in renal functions such as creatinine, blood urea nitrogen, 24 h proteinuria, and kidney injury molecule-1 with decrease in creatinine clearance, resulting in histological alternation and tubular damage with diffuse interstitial inflammation. …”
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Cardiovascular disease in pregnancy and its outcome: A prospective study by Dipali Prasad, Ravi Vishnu Prasad, Manoj Kumar Choudhary, Kanchan Kumari

“…Patients with medical disorders like Kidney disease, Liver disease, Pulmonary Disease, Diabetes Mellitus were excluded from the study. …”
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Phytochemical characterization and anti-arthritic potential of green-synthesized CuO nanoparticles derived from the Bistorta amplexicaulis root extract by Mahrukh Babar, Bilal Aslam, Muhammad Naeem Faisal, Abdul Malik, Suhail Akhtar, Sabiha Fatima, Wafa Majeed, Asher Umer, Muhammad Akmal Farooq

“…C-reactive protein (CRP), rheumatoid factor (RF), liver and kidney function biomarkers, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) levels showed a significant decrease at both low and high doses of green-synthesized CuO nanoparticles from the Bistorta amplexicaulis root extract. …”
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The association between HDL-c levels and computed tomography-based osteosarcopenia in older adults by Rongzhou Wang, Yu Wang, Zicheng Wei, Jiangchuan Wang, Hongye Tang, Xifa Gao, Jianhua Wang, Chao Zhang, Xiao Chen

“…Demographic information, including age, sex, and body mass index, and laboratory data, including liver and kidney function, blood lipids (HDL-c, low-density lipoprotein cholesterol (LDL-c), triglyceride (TG), total cholesterol (TC), blood glucose, and serum albumin, were collected from the medical records system. …”
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Globimetula braunii prevents hyperglycemia, oxidative damage, and hepatorenal dysfunction in dexamethasone-induced insulin-resistant rats by David Miaffo, Kilenma Kolefer, Elizé Dadaya, Barthelemy Maidadi, Abba Talba Mahamad, Albert Kamanyi

“…Body weight, glycemia, insulinemia, homeostatic model assessment for insulin resistance (HOMA-IR), markers of kidney and liver functions, and oxidative profile were assessed. …”
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Identification of Therapeutic Targets for Hyperuricemia: Systematic Genome-Wide Mendelian Randomization and Colocalization Analysis by Na Chen, Leilei Gong, Li Zhang, Yali Li, Yunya Bai, Dan Gao, Lan Zhang

“…<b>Background</b>: At present, there are still limitations and challenges in the treatment of hyperuricemia (HUA). …”
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The Role of γδ T Cells in Systemic Lupus Erythematosus by Meng Wu, Jinhua Yang, Xiaofeng Li, Junwei Chen

“…Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the overproduction of autoantibodies against an array of nuclear and cytoplasmic antigens and affects multiple organs, such as the skin, joints, kidneys, and neuronal tissues. T cells have been recognized as important players in the development of SLE due to their functions in cytokine secretion, antigen presentation, and supporting B cells for antibody production. γδ T cells are a minor population of T cells that play important roles in infection and tumor-associated disease. …”
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Emergent Unilateral Renal Artery Stenting for Treatment of Flash Pulmonary Edema: Fact or Fiction? by Asaad Akbar Khan, Eugene Patrick McFadden

“…Presence of bilateral renal artery stenosis or unilateral stenosis in combination with a single functional kidney in the susceptible cohort is usually blamed for this condition. …”
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Sutureless partial nephrectomy by S. V. Shkodkin, Yu. B. Idashkin, M. Z. A. A. Zubaidi, A. D. Kravets, A. F. Khuseinzoda, Zh. K. Askari, E. G. Ponomarev, V. Y. Nechiporenko, K. S. Shkodkin

“…The studies available for analysis were quite heterogeneous in terms of patient groups, inclusion criteria, and control points, which did not allow for a meta-analysis of the data presented.Results. An attempt to abandon the principle of kidney suturing after partial nephrectomy was implemented using methods of hemostasis based on the action of physical factors. …”
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Clinical and anamnestic characteristics of patients depending on left ventricular ejection fraction: results of a register study by P. G. Parfenov, A. V. Yurkina, D. P. Golubovskaya, S. Y. Shuster, E. V. Dren, Y. I. Guselnikova, N. B. Lebedeva, T. B. Pecherina

“…This category was also characterized by a more severe functional class of chronic heart failure (New York Heart Association); patients with functional class III– IV chronic heart failure prevailed (p &lt; 0.001). …”
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Hepatic and Renal Toxicity Induced by TiO2 Nanoparticles in Rats: A Morphological and Metabonomic Study by Xavier Valentini, Pascaline Rugira, Annica Frau, Vanessa Tagliatti, Raphaël Conotte, Sophie Laurent, Jean-Marie Colet, Denis Nonclercq

“…Enzymatic markers of liver and kidney functions (such as AST and uric acid) are also disrupted only in animals exposed to highest doses. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…[xvi]  Israni, A.K., et al., “Electronically Measured Adherence to Immunosuppressive Medications and Kidney Function after Deceased Donor Kidney Transplantation,” Clinical Transplantation 25, no. 2 (2011): 124-31. …”
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Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period by Junwei Fan, Junwei Fan, Peihao Wen, Liyun Yuan, Yan Xia, Shijie Hu, Xiaoqing Zhang, Zhihai Peng, Zhihai Peng

“…Trough blood concentrations in the clinical-SE group during the early postoperative period were higher than those in the clinical-FE and clinical-IE groups, which could lead to delayed recovery of liver (P = 0.0373) and kidney function (P = 0.0135) and a higher infection rate (P = 0.0086). …”
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The Associations of Dental and Periodontal Lesions with the Microvascular Complications in Patients with Type 2 Diabetes Mellitus: A Case–Control Study by Adina Andreea Mirea, Adela Gabriela Ștefan, Moța Maria, Diana Clenciu, Adina Mitrea, Ion Cristian Efrem, Maria Magdalena Roșu, Diana Cristina Protasiewicz-Timofticiuc, Beatrice Elena Vladu, Theodora Claudia Gheonea, Felicia Mărășescu, Moța Eugen, Ionela Mihaela Vladu

“…Results: Statistically significant differences were recorded between the two groups regarding the value of blood glucose, HbA1c and fibrinogen, as well as kidney function. Statistically significant differences were also recorded between the two groups when analyzing the presence of microvascular complications, as well as individually analyzed, in the case of diabetic peripheral sensory-motor neuropathy (<i>p</i> < 0.001), but also of diabetic retinopathy (<i>p</i> < 0.05). …”
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