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941
Association of fecal calprotectin and lipocalin-2 with subclinical intestinal inflammation and disease activity in patients with axial spondyloarthritis
Published 2025-12-01“…Measurement of ASDAS-ESR, ASDAS-CRP, BAS-MI, BAS-DI, BAS-FI, MASES, ASQoL, HAQ score, comorbidity assessment by BP measurement, lipid profile, kidney, liver function, FBS, 2hrPP, thyroid function tests, uric acid, ESR, CRP, HLA-B27, Plain-X ray of the affected joints. …”
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942
Temperature and WNK-SPAK/OSR1 Kinases Dynamically Regulate Antiviral Human GFP-MxA Biomolecular Condensates in Oral Cancer Cells
Published 2025-06-01“…Phase-separated membraneless biomolecular condensates in the cytoplasm and nucleus are now recognized to play a major role in modulating diverse functions in mammalian cells, and contribute to cancer pathogenesis through dysregulated function of condensates of transcription factors such as STAT3 and fusion oncoproteins. …”
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943
Urethral doubling in children and adolescents
Published 2023-04-01“…A little more than 200 cases of various forms of this defect have been described in the literature worldwide. We present a rare clinical case of duplication of the urethra in combination with the megaureter of the only functioning kidney. …”
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944
Unilateral renal agenesis in greater rhea (Rhea americana Linnaeus, 1758) reared under human care in the potiguar semiarid, Brazil
Published 2024-12-01“…In conclusion, unilateral renal agenesis in Greater Rhea is compatible with life. The contralateral kidney is fully functional and can meet the body's demands. …”
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945
Unilateral renal agenesis in greater rhea (Rhea americana Linnaeus, 1758) reared under human care in the potiguar semiarid, Brazil
Published 2024-12-01“…In conclusion, unilateral renal agenesis in Greater Rhea is compatible with life. The contralateral kidney is fully functional and can meet the body's demands. …”
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946
A Rare Culprit or an Elusive Culprit in Disguise? Unraveling Wild-Type ATTR Cardiac Amyloidosis in Heart Failure With Reduced Ejection Fraction
Published 2025-05-01“…Recent studies suggest that the incidence of wild-type transthyretin amyloidosis is rising, likely due to improved diagnostic techniques and an aging population. We present the case of a 72-year-old male with lower extremity edema, progressive shortness of breath, and worsening renal function. …”
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947
Early Focal Segmental Glomerulosclerosis as a Cause of Renal Allograft Primary Nonfunction
Published 2013-01-01“…In many cases the best treatment option is renal transplantation; however primary FSGS may rapidly recur in renal allografts and may contribute to delayed graft function. We present a case of primary nonfunction in a renal allograft due to biopsy-proven FSGS. …”
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948
Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal...
Published 2014-01-01“…Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR) have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. …”
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949
Development of an Experimental Model of Diabetes Co-Existing with Metabolic Syndrome in Rats
Published 2016-01-01“…The present study has developed a unique rodent model of metabolic syndrome, with diabetes as an essential component.…”
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950
Apoptosis-Associated Speck-Like Protein Containing a CARD Deletion Ameliorates Unilateral Ureteral Obstruction Induced Renal Fibrosis and Endoplasmic Reticulum Stress in Mice
Published 2018-01-01“…In the present study, we performed unilateral ureter obstruction (UUO) in both wild-type and ASC deletion mice to determine the contribution of ASC to renal fibrosis. …”
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951
Acute pyelonephritis complicated by subcapsular and perinephric hematoma: Diagnostic role of CT scan and 6-month follow-up
Published 2025-11-01“…Follow-up imaging revealed a subcapsular hematoma compressing the left kidney, with associated extension into the left psoas muscle. …”
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952
Polysome Profiling Proves Impaired IL-10 and Caspase-8 Translation in PBMCs of Hemodialysis Patients
Published 2025-02-01“…Triggered by uremic intoxication, a surplus of inflammatory mediators is present in the serum of hemodialysis (HD) patients. …”
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953
Topologically heterogeneous beta cell adaptation in response to high-fat diet in mice.
Published 2013-01-01“…<h4>Aims</h4>Beta cells adapt to an increased insulin demand by enhancing insulin secretion via increased beta cell function and/or increased beta cell number. While morphological and functional heterogeneity between individual islets exists, it is unknown whether regional differences in beta cell adaptation occur. …”
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954
Innovative nanostructured lipid-particles of apocynin and clove oil tagged with Chitin oligosaccharide for amelioration of tacrolimus-induced nephrotoxicity
Published 2025-08-01“…In vivo nephroprotective efficacy was evaluated in FK506-induced acute kidney injury (AKI) rat models, where oral administration of APO-loaded NSLCs significantly improved renal function and alleviated nephrotoxicity, as evidenced by biochemical markers and histopathological analyses. …”
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955
Generic residue numbering of the GAIN domain of adhesion GPCRs
Published 2025-01-01“…In summary, our work enables researchers to generate hypothesis and rationalize experiments related to GAIN domain function and pathology.…”
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956
The significance of anti-PLA2R antibody in the diagnosis and treatment of primary membranous nephropathy
Published 2019-01-01“…Anti-PLA2R may reappear or increase before the disease relapse, and when anti-PLA2R keeps positive or reappears after kidney transplantation, it suggests relapse of PMN. …”
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957
Serum Presepsin Levels among Patients with COVID-19
Published 2022-01-01“…Biochemical parameters including hemogram, coagulation tests, C-reactive protein (CRP), procalcitonin, creatine kinase, troponin, D-dimer, presepsin, and liver and kidney function tests were assessed for each patient. …”
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958
High vs. low vancomycin therapeutic concentrations in periprosthetic joint infection: A retrospective cohort analysis
Published 2025-03-01“…The PBPK model showed a greater increase in drug distribution to the bone marrow in the HC group (20.66 μg/mL vs. 14.34 μg/mL), with a smaller rise in the kidney (376.2 μg/mL vs. 327.7 μg/mL).ConclusionMaintaining vancomycin concentrations of 15–20 μg/mL is associated with better infection control for PJI patients who present with higher synovial WBC account, without compromising patient safety, joint function, or long-term quality of life.…”
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959
Heroin addict with gangrene of the extremities, rhabdomyolysis and severe hyperkalemia
Published 2012-01-01“…After stabilization of kidney function and improvement of his mental state, the patient agreed to undergo surgical procedure. …”
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960
Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review
Published 2025-01-01“…A clear association between survival and renal function could not be established because of the oncological risk on survival. …”
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