Paradigm shift on the role of mineralocorticoid receptor antagonists in hypertension therapy by S. R. Gilyarevsky, D. O. Ladygina

“…Modern data on the role of mineralocorticoid receptor antagonists (MRAs), in particular spironolactone, in the treatment of hyperaldosteronism and resistant hypertension are presented. The limitations of MRA use, which are mainly due to reduced kidney function, are considered. …”
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Endothelial Dysfunction and Cardiovascular Disease: Hyperbaric Oxygen Therapy as an Emerging Therapeutic Modality? by Tanja Batinac, Lara Batičić, Antea Kršek, Danijel Knežević, Emanuela Marcucci, Vlatka Sotošek, Božena Ćurko-Cofek

“…The latest findings on important topics will be presented, including the effects of HBOT on endothelial dysfunction, cardiac function, atherosclerosis, plaque stability, and endothelial integrity. …”
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The ameliorative potential of platelet-rich plasma and exosome on renal ischemia/reperfusion-induced uremic encephalopathy in rats by Hani M. Abdelsalam, Alaa Samy, Engy E. A. Mosaleem, Moustafa Salaheldin Abdelhamid

“…Renal Doppler ultrasonography was traced for all rats. Serum kidney functions and acetylcholine esterase enzyme (AchE) were evaluated. …”
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Renal Extramedullary Hematopoiesis in Mast Cell Leukemia with Bone Marrow Fibrosis by Damian T. Rieke, Laura K. Schmalbrock, Jana Ihlow, Karsten Kleo, Ann-Christin von Brünneck, Florian Nolte, Ulrich Keller, Sebastian Ochsenreither

“…The patient presented to our clinic with acute kidney failure because of renal extramedullary hematopoiesis. …”
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PRACTICAL USE OF EXTRACORPOREAL MEMBRANE OXYGENATION IN ORGAN DONATION FOR TRANSPLANTATION by M.G. Minina, M.Sh. Khubutia, K.K. Gubarev, V.A. Gulyaev, A.V. Pinchuk, M.M. Kaabak, B.V. Dabasambueva

“…The rate of delayed graft function (DGF) following the DBTL perfusion may vary from 48 to 78,4%. …”
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Use of Continuous Renal Replacement Therapy for Removal of Dabigatran in a Patient in Need of Emergent Surgery by Sara E. Parli, Melissa L. Thompson Bastin, Daniel A. Lewis

“…Greater than 80% of the drug was removed due to 4 hours of CRRT and residual kidney function. Reversal of dabigatran is an area of current research with recent FDA approval of idarucizumab for use. …”
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Ablative Therapies for Localized Primary Renal Cell Carcinoma by Muhammad Ali, Vanessa Acosta Ruiz, Sarah P. Psutka, David Liu, Shankar Siva

“…Modest post-SABR renal function decline has been observed. Despite most patients presenting with mild or moderate chronic kidney disease there is less than a 5% chance of progression to end-stage renal disease. …”
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Identification of a novel GJA3 mutation in a large Chinese family with congenital cataract using targeted exome sequencing. by Yihua Yao, Xuedong Zheng, Xianglian Ge, Yanghui Xiu, Liu Zhang, Weifang Fang, Junzhao Zhao, Feng Gu, Yihua Zhu

“…The results of the bioinformatic analysis showed that the mutation was deleterious to the structure and hemichannel function of Cx46 encoded by GJA3. Plasmids expressing wild-type and mutant human Cx46 were constructed and ectopically expressed in human lens epithelial cells (HLECs) or human embryonic kidney (HEK-293) cells. …”
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Insulin resistance contribution to pathogenesis of cardiac remodeling in patients with hypertension in combination with obesity and type 2 diabetes by M. E. Statsenko, M. V. Derevyanchenko

“…Canonical analysis showed that an increase in the median values of Insulin Resistance function in all groups was associated with a deterioration in the median values of Cardio function.Conclusion. …”
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A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis. by Sunwoo Chun, Takeshi Bamba, Tatsuya Suyama, Tomoko Ishijima, Eiichiro Fukusaki, Keiko Abe, Yuji Nakai

“…A high phosphorus (HP) diet causes disorders of renal function, bone metabolism, and vascular function. We previously demonstrated that DNA microarray analysis is an appropriate method to comprehensively evaluate the effects of a HP diet on kidney dysfunction such as calcification, fibrillization, and inflammation. …”
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Minimally invasive open dismembered pyeloplasty technique: Miniature incision, muscle-splitting dissection, and nopelvis reduction in children by Farzaneh Sharifiaghdas, Mahboubeh Mirzaei, Azar Daneshpajooh, Shahin Abbaszadeh

“…All patients had a documented ureteropelvic junction obstruction (having T1/2 more than 20 min in diethylenetriaminepentaacetic acid [DTPA] scan) with symptomatic stenosis or decreased kidney function (differential function <40%). Pyeloplasty was done by a retroperitoneal flank approach with miniature incision without pelvis reduction. …”
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The Outcome of COVID-19 Patients with Moderate to Severe Disease: A Single Institution Study by Iffat Rafeeq, Anees Ahmed Gardezi, Nuzhat Rafeeq, Shagufta Parveen, Abeera Ahmad

“…Investigations including complete blood count, serum ferritin, quantitative CRP, liver function tests, renal function tests, blood sugar fasting, and random chest radiographs and ECG were performed. …”
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Ureteral duplication anomalies: two years’ experience in a single center by Ahmed Oshiba, Samar Oshiba, Mostafa Kotb, Mohamed Abouheba

“…Lower moiety pelviureteric junction obstruction was diagnosed in only 1 case. 13 cases were diagnosed with ureterocele obstructing the upper moiety segment (9 left-sided, 4 right-sided), of which 2 presented early with dysplastic upper moiety in 1 and dysplastic whole kidney in the other, and 4 were cecoureterocele and prolapsing through bladder neck obstructing the bladder outlet. …”
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Aurora kinase B inhibitor AZD1152: repurposing for treatment of lupus nephritis driven by the results of clinical trialsResearch in context by Yue Zhao, Zuguo Zheng, Xuexiao Jin, Shaoshan Liang, Changming Zhang, Mingchao Zhang, Yue Lang, Ping Li, Zhihong Liu

“…Transcriptome sequencing and functional assays were performed to elucidate its mechanisms of action. …”
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Severe circulatory failure caused by acute cardiac dysfunction in a young man with leptospirosis living in a slum of Rome, Italy (REV JI-PH-D-24–01876R3) by Salvatore Lucio Cutuli, Fabiana Rizzo, Gennaro De Pascale, Silvia Costantini, Anna Maria Marella, Massimo Antonelli, Alessandra Ciervo

“…Leptospirosis may cause severe disease characterized by acute kidney injury, hepatic failure, or multiorgan dysfunction, including cardiac manifestations. …”
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Neutrophil-Mimetic oleanolic acid-loaded Liposomes targeted to alleviate oxidative stress for renal ischemia-reperfusion injury treatment by Qiaojing Chen, Daping Xiao, Yi Wang, Zheng Zhang, Xinlu Lin, Qing Ji, Yingmin Han, Lingan Yu, Jinglin Xu

“…Acute kidney injury (AKI) is a prevalent clinical condition characterized by a sudden decline or loss of renal function, exacerbated by the lack of effective diagnostic and therapeutic tools. …”
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The Increasing Problem of Resistant Hypertension: We’ll Manage till Help Comes! by Francesco Natale, Rosa Franzese, Ettore Luisi, Noemi Mollo, Luigi Marotta, Achille Solimene, Saverio D’Elia, Paolo Golino, Giovanni Cimmino

“…Finally, the renal denervation is also proposed in patients with preserved kidney function that remain hypertensive despite the use of maximum tolerated medical treatment. …”
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The Expanding Role of GLP-1 Receptor Agonists: Advancing Clinical Outcomes in Metabolic and Mental Health by Mohamad Al Qassab, Mohammad Mneimneh, Ahmad Jradi, Bassem Derbas, Dana Dabboussi, Justine Khoury Baini, Nadia Katrib, Nadim Chaarani, Philippe Attieh, Amjad Kanaan, Frederic Harb, Sami Azar, Hilda E. Ghadieh

“…Furthermore, they promote natriuresis and stabilize renal function. Moreover, GLP-1 RAs present significant cardiovascular benefits, including improved myocardial function, reduced atherosclerosis progression, enhanced endothelial health, and decreased major adverse cardiovascular events (MACEs). …”
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Leptin signalling altered in infantile nephropathic cystinosis‐related bone disorder by Wai W. Cheung, Ping Zhou, Ronghao Zheng, Arieh Gertler, Eduardo A. Oliveira, Robert H. Mak

“…Patients with INC develop Fanconi syndrome and chronic kidney disease (CKD) with significant bone deformations. …”
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Non-Permanent Transcatheter Proximal Renal Artery Embolization for a Grade 5 Renal Injury with Delayed Recanalization and Preserved Renal Parenchymal Enhancement by Abhishek Jairam, Bradley King, Zachary Berman, Gerant Rivera-Sanfeliz

“…Interestingly, imaging 1 month after embolization revealed residual enhancement of the inferior pole of the kidney, suggesting reconstitution of flow and partial renal salvage. …”
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