Enhanced renoprotective effect of GDNF-modified adipose-derived mesenchymal stem cells on renal interstitial fibrosis by Shulin Li, Yanping Wang, Zhuojun Wang, Lu Chen, Bangjie Zuo, Caixia Liu, Dong Sun

“…Conclusion Collectively, our data indicated that the GDNF gene enhances the ability of AMSCs in improving renal microcirculation through PI3K/Akt/eNOS signaling pathway and afterward inhibit the EndMT process and kidney fibrogenesis, which should have a vast of implications in designing future remedies for chronic kidney disease (CKD) treatment.…”
Get full text

Tuberculous abdominal aortic aneurysm: Management and outcomes by Sree Vani Paladugu, MS, Ajay Savlania, MCh, Gokulkrishnan Hari, MS, Tanuj Singla, MS, Shreyas Srinivasan, MBBS, Ujjwal Gorsi, DM, Mustafa Razi, MD, Pradeep Burli, MD, Prem Chand Gupta, MS

“…Surgical techniques should be tailored to the presentation, and functional status of the patient weighing the risk-benefit ratio of infection-related complications, patency of revascularization, and ability to tolerate the procedure.…”
Get full text

Vesicoureteral Reflux Detected on Post-void Image of 99m Tc MAG3 Renal Scintigraphy by Naureen Nizar, Akhtar Ahmed

“…On the post-void delayed image of 99m Tc MAG3 scintigraphic scan vesicoureteral reflux was detected in left non-functioning kidney, which was missed on voiding cystourethrography.…”
Get full text

A Rare Case of Xanthogranulomatous Pyelonephritis with Spontaneous Renocolic Fistula and IVC Thrombosis by Daniele Sforza, Leandro Siragusa, Matteo Ciancio Manuelli, Linda De Luca, Bruno Sensi, Simona Grande, Renato Argirò, Marco Nezzo, Massimo Villa, Michele Grande

“…Xanthogranulomatous pyelonephritis (XGPN) is a rare disorder affecting the kidney which can fistulise to the colon in exceptional cases. …”
Get full text

Poisoning by <i>Atractylus gummifera</i> L. Roots in Grazing Cattle of a Sicilian Farm by Clara Naccari, Giulia Donato, Vincenzo Naccari, Ernesto Palma, Pietro Paolo Niutta

“…In the surviving cattle, symptomatic drug therapy was administered, and hematological and biochemical analyses (blood, liver, and kidney profiles) were carried out during treatment. …”
Get full text

Connective tissue dysplasia syndrome in nephrology. Literature review by R. A. Zorina, I. V. Zorin

“…Therefore, connective tissue dysplasia requires a targeted search for criteria for identifying patients at risk for kidney damage.…”
Get full text

Spectrum of rapidly progressive (Crescentic) glomerulonephritis at a referral diagnostic center in Nepal: one year study by Nirajan Mainali, Rupenra Thapa

“…Background: A clinical syndrome manifested by features of glomerular disease in the urinalysis and by progressive loss of kidney function over a comparatively short period is called rapidly progressive glomerulonephritis (RPGN). …”
Get full text

LYSOZYME-INDUCED NEPHROPATHY IN CMML: A RARE BUT SIGNIFICANT COMPLICATION REQUIRING EARLY RECOGNITION AND INTERVENTION by Alfadil Haroon, Mohamed Kindawi, Ahmed S Alotaibi, Ali Debsan Alahmari, Hazzaa Alzahrani, Mansour Alfayez, syed Osman Ahmed

“…Filtered lysozyme accumulates in the renal cortex, causing severe hypokalemia via kaliuresis or direct tubular injury, potentially leading to kidney failure. In our patient CMML treatment, hydration and steroids restored kidney function. …”
Get full text

Wilson’s Disease, Etiology and Treatment by Feryal Rada

“…The deposition of copper in many organs, such as the liver, eyes, kidneys, and basal ganglia in the brain is the main cause of this disease. …”
Get full text

A case of crescentic glomerulonephritis with exacerbation of pre-existing IgA nephropathy after COVID-19 by Esra Karabağ Yılmaz, Seha Saygılı, Gülüstan Musayeva, Rüveyda Gülmez, Ayşe Ağbaş, Yasemin Özlük, Nur Canpolat

“…It is therefore necessary to closely monitor the kidney function of patients with underlying glomerulonephritis during and after COVID-19 and consider an early biopsy if serum creatinine does not return to baseline levels. …”
Get full text

FIRST EXPERIENCE OF THE URETERO-URETEROANASTOMOSIS (URETEROPYELOANASTOMOSIS) IN CHILDREN WITH COMPLETE URETERAL DUPLICATION by I. M. Kagantsov, V. V. Sizonov, V. I. Dubrov, S. G. Bondarenko, N. R. Akramov, O. S. Shmyrov, G. I. Kuzovleva, R. V. Surov, A. A. Longval

“…It is a safe technique which allows to minimize the risk of loss of duplex kidney function.…”
Get full text

Association between self-stigma and diabetic complications in Japanese people with type 2 diabetes: a cross-sectional study by Asuka Kato, Yasutaka Maeda, Masae Minami, Daiji Kawanami, Mayuko Yamamoto, Yuichi Takashi, Masashi Ishizu, Kyoko Toyokawa, Dai Nagata, Kensuke Makihata, Haruki Koganemaru, Tomoki Sakamoto, Kayoko Teshima, Yuka Urata, Yoshimi Muta, Hisashi Yokomizo, Dan Sekiguchi

“…In contrast, no significant association was observed between the SSS-J score quartiles and decreased kidney function.Conclusions The presence of DR was more strongly associated with self-stigma than DKD. …”
Get full text

Possibilities of hyperuricemia correction in acute decompensation of heart failure by Laura H. Sarieva, Svetlana N. Nasonova, Marina D. Muksinova, Igor V. Zhirov, Sergey N. Tereshchenko

“…The results of standard therapy of HF with diuretic therapy in combination with xanthine oxidase inhibitor – allopurinol in the starting dose of 50 mg in 36 patients with ADHF of functional class II–IV, hyperuricemia, reduced renal filtration function calculated by the CKD-EPI formula are presented. …”
Get full text

IL-27 Modulates Mesenchymal Stem Cell Immunoplasticity for Enhanced Lupus Nephritis Therapy via the JAK1–STAT1–IDO Axis and Tryptophan Metabolic Orchestration by Cheng Zhou, Shunlai Shang, Jing Zhao, Yunzhao Yang, Meihan Shi, Ping Li, Qinggang Li, Jian Zhang, Wenge Li, Chuyue Zhang, Xue-Yuan Bai

Get full text

Fatal disseminated mucormycosis due to Cunninghamella bertholletiae infection after ABO-incompatible living donor liver transplantation: a case report by Atsuyoshi Mita, Shohei Hirano, Takeshi Uehara, Kai Uehara, Yasunari Ohno, Koji Kubota, Yuichi Masuda, Tsuyoshi Notake, Kazuki Yoshizawa, Akira Shimizu, Yuji Soejima

“…Multiple infarctions in the brain, heart, and kidney developed within 2 weeks. Treatment with amphotericin B was ineffective. …”
Get full text

Tomato Powder Modulates NF-κB, mTOR, and Nrf2 Pathways during Aging in Healthy Rats by Kazim Sahin, Cemal Orhan, Mehmet Tuzcu, Hakki Tastan, Birdal Bilir, Nurhan Sahin, Deniz Aslar Oner, Omer Kucuk

“…TP supplementation significantly reduced the hyperglycemia, hypertriglyceridemia, and hypercholesterolemia and improved liver function and kidney function in 77-week old rats compared with the control animals (P<0.05). …”
Get full text

Renal Dysfunction in a Patient With Crohn's Disease During Ustekinumab Treatment: A Case Report and Review of the Literature by Yuge Wei, Ms, Gechong Ruan, MD, Yan Qin, MD, Xiaoyin Bai, MD, Hong Yang, MD

“…The findings underscore the importance of close monitoring of renal function in patients receiving ustekinumab, particularly those with preexisting kidney disease or risk factors for renal dysfunction.…”
Get full text

Effects of Varicocelectomy Surgery on Sperm Morphology and Male Fertility by Mir Abid Jan, Shaukat Fiaz, Ismail Khan, Syed Zia Ur Rahman, Khalil Ur Rehman

“…It has been demonstrated that microsurgical varicocelectomy enhances testicular function. The present study aimed to investigate the effect of microsurgical varicocelectomy on sperm morphology. …”
Get full text

Sodium–glucose Cotransporter 2 Inhibitors in Heart Failure: Potential Mechanisms of Action, Adverse Effects and Future Developments by Juan Tamargo

“…In type 2 diabetes (T2D), some SGLT2Is reduce major cardiovascular events, heart failure hospitalisations and worsening of kidney function independent of glycaemic control. …”
Get full text

Inferior vena cava obstruction secondary to hepatic alveolar echinococcosis: a case report by Jingxin Yan

“…Interventional treatments significantly could improve liver function, thereby facilitating future treatment options. …”
Get full text