Biomarkers of residual risk and all-cause mortality after acute coronary syndrome. by Anna Toso, Mario Leoncini, Mauro Maioli, Simona Villani, Francesco Bellandi

“…Diversification of secondary preventive measures based on routine evaluations of inflammation and kidney function markers, not only LDL-C, could lead to better targeted reduction of residual risk after ACS.…”
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An R package for survival-based gene set enrichment analysis by Xiaoxu Deng, Jeffrey Thompson

“…We developed an R package and Shiny app called SGSEA and presented a study of kidney renal clear cell carcinoma (KIRC) to demonstrate the approach. …”
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The Impact of Epigenetics on the Pathophysiology of Type 2 Diabetes and Associated Nephropathic Complications by Amit Mukherjee, Tanusree Debbarman, Basu D. Banerjee, Sheelu S. Siddiqi

“…Advancements in epigenome profiling provide valuable insights into the functional outcomes and chromatin states of cells impacted by T2D. …”
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Baxdrostat and finerenone: new aldosterone synthase-aldosterone-mineralocorticoid receptor hormonal system inhibitors for the drug treatment of resistant arterial hypertension by O. B. Kuzmin, N. V. Buchneva, V. V. Belyanin, V. V. Zhezha, M. V. Stolbova

“…However, the inclusion of this drug in antihypertensive therapy not only fails to control blood pressure in a significant proportion of patients with resistant hypertension, but also significantly increases the risk of hyperkalemia, especially in people with impaired renal function. The review presents data on the pharmacodynamics and pharmacokinetics of new inhibitors of aldosterone synthase-aldosterone-mineralocorticoid receptor hormonal system baxdrostat and finerenone, as well as the results of clinical studies assessing the clinical effectiveness and safety profile of these drugs in patients with resistant hypertension.…”
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Organ-on-a-chip Technology in Urology by A. G. Vardikian, S. V. Piatnitskaia, V. A. Solntsev, B. I. Shamsov, V. N. Pavlov

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Arterial Hypertension in Older Adults in the Light of New European Guidelines 2018 by O. D. Ostroumova, A. I. Kochetkov, M. S. Cherniaeva

“…It is recommended to investigate the level of serum creatinine more often to evaluate the kidney function and to detect a possible decrease in the glomerular filtration rate  because of a decrease in BP and  perfusion of the kidneys. …”
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Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité c... by Samia BOUDANI, Faiza ZERDOUMI, Naouel FZ. BOUMANSOUR, Abbou KADDOUS, Bachir M. GUELLIL

“…The survival of patients with chronic kidney disease (CKD) depends on several factors, abnormal nutritional status such as obesity or protein-energy malnutrition are among these factors. …”
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Can high-sensitivity C reactive protein (hsCRP) be used as a prognostic marker of functional disability after acute ischaemic stroke? A cross-sectional study at a tertiary care cen... by Vijay Kumar, Ratnadeep Biswas, Vishnu Shankar Ojha, Kotha Vamshikrishnapatel

“…Objectives This study was conducted with the aim of assessing the correlation between highly sensitive C reactive protein (hsCRP) levels and indicators of disability and functional impairment in individuals presenting with acute ischaemic stroke (AIS).Design Cross-sectional study.Setting Department of General Medicine at the All India Institute of Medical Sciences, Patna, Eastern India from August 2022 to August 2023.Participants The study population comprised a total of 125 patients aged 18 years or more, presenting within 48 hours of symptom onset or time last known well and having confirmed ischaemic stroke through CT or MRI of the brain. …”
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Hypoxia-inducible factors: details create a picture. Part II. HIF-2 by G. A. Ignatenko, N. N. Bondarenko, A. V. Dubovaya, T. S. Ignatenko, Ya. S. Valigun, E. A. Belyaeva, V. G. Gavrilyak

“…The structural and functional features of HIF-2 subunits (HIF-2α and HIF-β) and methods of their regulation under conditions of normoxia and hypoxia are described. …”
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Ethnic differences in CKD progression among people with type 2 diabetes and rapid eGFR decline: A secondary data analysis by Thamer Alobaid, Matthew D. L. O’Connell, Janaka Karalliedde, Salma Ayis

“…Abstract Background People with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) exhibit diverse patterns of kidney function decline. …”
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Evaluation of CRP SNV rs2808630 and acute proinflammatory biomarkers in patients with CKD and PLHIV with CKD: a case-control study by Andrea Torres-Rojas, Luz Alicia González-Hernández, Karina Sánchez-Reyes, Jonathan Samuel Chávez-Iñiguez, Jorge Fernando Topete-Reyes, Jaime Federico Andrade-Villanueva, Pedro Martínez-Ayala, Adriana Valle-Rodriguez, Vida Verónica Ruiz-Herrera, Jorge Hernández-Bello, Zyanya Reyes-Castillo, Monserrat Álvarez-Zavala

“…Of the 358 samples, 221 (61.7%) present the wild-type genotype. The results analyzed correspond with what has been reported worldwide in studies of CRP SNV rs2808630 in the development of CKD without having a relationship with inflammatory and kidney function biomarkers. …”
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Dendrobium huoshanense C. Z. Tang and S. J. Cheng can be prepared as a food with the ability to prevent and treat hyperuricaemia by Qing Hao, Lin Jiang, Jun Ma, Huikai Wang, Ying Liu, Qichang Xu, Songze Li, Song Han, Qiusheng Zheng, Xiangcheng Fan, Xiangcheng Fan, Jichun Han

“…BackgroundHyperuricemia (HUA) is the presence of excessive uric acid (UA) in blood, which leads to an increased risk of chronic kidney disease and gout. There are about 120 million hyperuricemia patients in China, which has surpassed diabetes as the second largest chronic disease.ObjectiveThe aim of the present study was to investigate the hypouricemic effects of Dendrobium huoshanense C. …”
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Uromodulin — Biological Significance and Prospects for Clinical Use by E. S. Levitskaya, M. M. Batiushin, M. Z. Gasanov

“…At the same time, it is known that uromodulin is an incompletely studied protein both in terms of structure and features of the functions it performs. A thorough analysis of research data, including experimental work on the study of uromodulin in domestic and international literature sources, was carried out, with a presentation of the material in this manuscript.…”
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A CASE OF LATE DIAGNOSIS OF FAMILIAL MEDITERRANEAN FEVER COMPLICATED BY AA-AMYLOIDOSIS by S. I. Shchadneva, E. E. Ustinova, L. V. Belozertseva, V. V. Gorbunov, N. S. Kurbatova

“…The diagnosis of systemic lupus erythematosus was doubtful and to clarify the nature of kidney morphological changes nephrobiopsy was performed that revealed the presence of kidneys AA-amyloidosis. …”
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Contrast-induced nephropathy in patients with acute coronary syndrome with ST-segment elevation: risk factors and prognosis by O. V. Arsenicheva, N. N. Shchapovа

“…Among patients with СIN, persons aged over 75 years (60 %), with diabetes mellitus (45 %), chronic kidney disease (75 %), postinfarction cardiosclerosis (50 %), chronic heart failure of functional class III–IV (80 %), developed acute heart failure T. …”
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Intracapillary Monoclonal IgM Deposition Concomitant With Cold Agglutinin Disease by Silvia M. Titan, Sandra Herrmann, Nelson Leung, Pingchuan Zhang, Stephen Ansell

“…This article reports a case of a female on her 60s who was referred to Nephrology for evaluation of worsening kidney function, hematuria, and proteinuria. Her medical history was notable for marginal zone lymphoma along with immunoglobulin M (IgM)-kappa cold agglutinin disease diagnosed 3 years before the current presentation, which had been treated with rituximab. …”
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Sarcopenia in Peritoneal Dialysis: Prevalence, Pathophysiology, and Management Strategies by Xiaohua Hu, Bibo Wu, Yang Yang, Liming Zhang, Cheng Xue

“…Sarcopenia, defined as the loss of skeletal muscle mass, strength, and function, is a significant complication in patients with chronic kidney disease, particularly those undergoing peritoneal dialysis (PD). …”
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Long-Term Follow-Up of a Glucocorticoid Minimizing Regimen for the Treatment of Severe Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis by Stephen P. McAdoo, Ruth J. Pepper, Maria Prendecki, Amrita Dhutia, Tony Lopez, Aine Burns, Marie Condon, Sally Hamour, Megan Griffith, Jeremy Levy, Tom Cairns, Mark Little, Alan D. Salama, Charles D. Pusey

“…Early improvements in disease activity and kidney function—and in long-term kidney and patient survival—were comparable with a previous cohort treated with an equivalent rituximab-cyclophosphamide regimen and a conventional GC taper, whereas adverse events (infection, new-onset diabetes) were less frequent. …”
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Defining Nephritic Factors as Diverse Drivers of Systemic Complement Dysregulation in C3 Glomerulopathy by Jill J. Hauer, Yuzhou Zhang, Renee Goodfellow, Amanda Taylor, Nicole C. Meyer, Sarah Roberts, Dingwu Shao, Lauren Fergus, Nicolo Ghiringhelli Borsa, Monica Hall, Carla M. Nester, Richard J.H. Smith

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IgA Nephropathy and IgA Vasculitis Post-COVID-19 vaccination: A case-based review by Arun Prabhahar, Prabhat Chauhan, Aravind Sekar, Ritambhra Nada, Manish Rathi, Harbir Singh Kohli, Raja Ramachandran

“…The kidney functions are relatively preserved, and the short-term clinical outcomes are favourable.…”
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