Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis by Congjuan Luo, Feng Luo, Lin Che, Hui Zhang, Long Zhao, Wei Zhang, Xiaofei Man, Quandong Bu, Hong Luan, Bin Zhou, Haiyan Zhou, Yan Xu

“…Objective The present study investigated the specific mechanism by which mesenchymal stem cells (MSCs) protect against sepsis-associated acute kidney injury (SA-AKI).Methods Male C57BL/6 mice underwent cecal ligation and puncture surgery to induce sepsis and then received either normal IgG or MSCs (1 × 106 cells, intravenously) plus Gal-9 or soluble Tim-3 3 h after surgery.Results After cecal ligation and puncture surgery, the mice injected with Gal-9 or MSCs plus Gal-9 had a higher survival rate than the mice in the IgG treatment group. …”
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Simultaneous Bilateral Knee Extensor Mechanism Injury in a Young Male: A Clinical Diagnosis and Literature Review by Bulelwa Andiswa Klaas, Collen Sandile Nkosi

“…Surgical repair was performed earlier, and he achieved good functional outcomes.…”
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A `glue sniffer` teenager with anuric renal failure and hepatitis by Ali Yurtseven, Mümine Türksoylu, Pınar Yazıcı, Bülent Karapınar, Eylem Ulaş Saz

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Supraselective embolization as a method for the management of renal vascular injuries by Milović Novak, Bančević Vladimir, Jakovljević Olivera, Paunić Zoran

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Effect of long-term blood pressure trajectory on the future development of chronic kidney disease: an analysis of data from the Korean National Insurance Health Checkup Study by Wonmook Hwang, Eu Jin Lee, Jae-Hyeong Park, Soon-Ki Ahn

“…OBJECTIVES Chronic kidney disease (CKD) is a prevalent health issue that causes the irreversible loss of functioning nephrons, end-stage renal disease, cardiovascular disease, and premature mortality. …”
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A Novel Protocol for Culturing Polarized Proximal Tubular Epithelial Cells from Kidney Biopsies: Enhancing Platforms for Drug Excretion and Nephrotoxicity Studies by Tadej Petreski, Lidija Gradišnik, Luka Varda, Polona Kovačič, Jurij Dolenšek, Andraž Stožer, Sebastjan Bevc, Uroš Maver

“…Cells cultured on Transwell plates exhibited native polarization, expressing transporters crucial for drug excretion on apical and basolateral surfaces. We present two robust protocols for isolating and characterizing PTECs, offering a scalable method to obtain functional, polarized cells from scarce biopsy material. …”
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Piezo1 aggravates ischemia/reperfusion-induced acute kidney injury by Ca2+-dependent calpain/HIF-1α/Notch signaling by Xiaoting Chen, Jintao Jiang, Bin He, Shangfei Luo, Qiaorui Tan, Youfen Yao, Rentao Wan, Honglin Xu, Silin Liu, Xianmei Pan, Xin Chen, Jing Li

“…In conclusion, our findings elucidate the biological functions of Piezo1 in renal macrophages, underscoring its role as a crucial mediator of acute kidney injury. …”
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EFFECTS OF SMOKING ON CIRCADIAN ARTERIAL BLOOD PRESSURE PROFILE IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME AND CHRONIC KIDNEY DISEASE by Oksana Yadzhyn, Tetiana Solomenchuk

“…The paper presents the results of a study of the effects of smoking on circadian arterial blood pressure (ABP) profile in patients with Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Chronic Kidney Disease (CKD). …”
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Cefepime-Induced Encephalopathy in a Patient With Uncompromised Renal Function: A Case Report by Aayusha Dhakal, Ozone Gautam

“…This is a rare case report where a patient with intact kidney function presented with confusion and incoherence. …”
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Effect of transurethral resection of the prostate on renal function in patients with renal insufficiency not needing dialysis by Montadhar Hameed Nima, Mohammed Ghanim Alwan, Thaer Saleh Al-Omary

“…The outcome for renal function following TURP is better for patients with renal insufficiency, whose serum creatinine levels are lower at presentation. …”
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Multidisciplinary approach to the treatment of a patient with juxtarenal abdominal aortic aneurysm and renal cell cancer by A. V. Chupin, N. R. Masalimov, T. P. Baitman, A. A. Gritskevich, V. A. Kulbak, I. V. Miroshkina, E. V. Kondratyev, Ya. A. Stepanova, I. E. Timina

“…After 6 months, on the control computed tomography of the abdominal organs with contrast enhancement (CT) of the abdominal cavity with CU, the prosthesis of the abdominal aorta and the left renal artery are functioning. According to color duplex scanning (CDS) of the renal vessels, the blood flow in the left kidney is preserved to the periphery with normal speed indicators. …”
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Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo by Summya Rashid

“…On the 21st day, rats were killed, and biochemical, histological, serological, and molecular analyses were conducted using kidney tissues and blood samples.Results5-FU induced kidney injury, as evidenced by alterations in kidney function markers (BUN, Cr, LDH, KIM-1), lipid peroxidation (LPO), ROS generation, histological changes, and a reduction in antioxidant defense mechanism (GSH, GR, GPx, and CAT). …”
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Risk factors and the level of laboratory biomarkers abnormalities amongst COVID-19 admitted patients with acute kidney injury: A retrospective cross-sectional study by Mahdi Zarei, Juan Carlos Cotrina-Aliaga, Samaneh Atbaeitabari, Mohammad Darvishi, Sepideh KarkonShayan, Reza Akhavan-Sigari

“…The association between blood biomarkers, including hematologic and inflammatory markers indicate their potential role in the impairment of kidney function.…”
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Recognition and management of community-acquired acute kidney injury in low-resource settings in the ISN 0by25 trial: A multi-country feasibility study. by Etienne Macedo, Ulla Hemmila, Sanjib Kumar Sharma, Rolando Claure-Del Granado, Henry Mzinganjira, Emmanuel A Burdmann, Jorge Cerdá, John Feehally, Fredric Finkelstein, Guillermo García-García, Vivekanand Jha, Norbert H Lameire, Euyhyun Lee, Nathan W Levin, Andrew Lewington, Raúl Lombardi, Michael V Rocco, Eliah Aronoff-Spencer, Marcello Tonelli, Karen Yeates, Giuseppe Remuzzi, Ravindra L Mehta, ISN 0by25 Trial Study Group

“…Of 504 patients with kidney function assessed during the 6-month follow-up, de novo CKD arose in 79/484 (16.3%), with no difference between the observation and intervention phase (95% CI 0.91, 2.47; p = 0.101). …”
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Retinal multimodal-imaging and functional tests in a mitochondrial disease with focal and segmental glomerulosclerosis by Xiao-Hong Liu, Xi Shen, Yi-Sheng Zhong

“…Renal involvement associated with this mutation generally manifests as subnephrotic proteinuria, progressive deterioration of kidney function, and increased morbidity. The retinopathies linked to the m.3243A>G mutation have heterogeneous presentations, characterized by variable degrees of retinal pigment epithelium (RPE) atrophy and hyperpigmentation at the posterior pole. …”
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Do mismatches between pre- and post-natal environments influence adult physiological functioning? by Tony Robertson, Michaela Benzeval

“…Higher birthweight and longer leg length were associated with better kidney function (eGFR). However, there was no evidence for mismatches between birthweight and leg length to be associated with worse sBP, FEV1, HbA1c, eGFR or GGT levels (P>0.05).…”
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The impact of active components from on the growth, intestinal barrier function, and immunity of broiler chickens by Luli Zhou, Guanyu Hou, Hanlin Zhou, Khaled Abouelezz, Yuxiu Ye, Dingfa Wang

“…Conclusion The present study provides preliminary evidence that VR and PT are two of the main active compounds in PSE, which can cooperatively improve growth performance, intestinal barrier integrity, and immune function in chickens.…”
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Correlation between computed tomography findings and liver function parameters in chronic liver disease by Moeen ud din Khan Khalil, Syed Kazim Shah Bukhari, Syed Murtaza Shah Bukhari, Mian Zia Shah, Mian Raza Shah

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Mortality and Graft Failure With Medical Management Alone Versus Revascularization After Coronary Angiography Among Kidney Transplant Recipients: A Population-Based Study by Labib I. Faruque, Robert R. Quinn, Pietro Ravani, Tyrone G. Harrison, Brenda Hemmelgarn, Stephen Wilton, Alix Clarke, Matthew T. James, Ngan N. Lam

“…Patients: We included adult, kidney-only transplant recipients between January 1997 and March 2015 who survived at least 1-year post-transplant with a functioning graft and had a coronary angiography during follow-up. …”
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Acute unilateral renal embolism: a therapeutic challenge by Long Cheng, Xuanlin Chen, Chongjun Shi, Fanfei Zeng, Weizhong Yang, Huage Cai, Caiyong Lai

“…At the one-year follow-up, severe atrophy of the affected kidney and compensatory enlargement of the contralateral kidney were observed. …”
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