Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. by Miki Nagase, Hidetake Kurihara, Atsu Aiba, Morag J Young, Tatsuo Sakai

“…In the present study, we examined whether Rac1 in macrophages effects cytokine production and the inflammatory mechanisms contributing to kidney derangement. …”
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Visceral Leishmaniasis in a 25-Year-Old Female Kidney Transplant Recipient from a Non-Endemic Region: A Case Report from Romania by Alin Gabriel Mihu, Mariana Patiu, Delia Monica Dima, Daniela Adriana Oatis, Cristina Mihaela Cismaru, Rodica Lighezan, Tudor Rares Olariu

“…She was quickly sent to Victor Babes Infectious Disease Hospital in Bucharest for additional tests and treatment. The kidney function of the patient was maintained. This case highlights the importance of considering leishmaniasis in immunosuppressed patients presenting with unexplained cytopenia, even in non-endemic regions. …”
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Injured tubule derived CCN1 exacerbates renal congestion-mediated acute kidney injury and fibrosis by Atsushi Minamida, Tomohiro Nakata, Ryo Kurose, Shinji Sawai, Masashi Nakamura, Minato Umehara, Hiroko Yamauchi-Sawada, Yasuto Sunahara, Yayoi Matoba, Natsuko Okuno-Ozeki, Itaru Nakamura, Kunihiro Nakai, Noriyuki Yamashita, Yuhei Kirita, Keiichi Tamagaki, Satoaki Matoba, Tetsuro Kusaba

“…CCN1 was upregulated in the acute phase following kidney injury with renal congestion, and phosphorylated focal adhesion kinase (pFAK), a downstream molecule of CCN1, was present in fibroblasts at injury sites. …”
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α-Klotho: An Early Risk-Predictive Biomarker for Acute Kidney Injury in Patients with Acute Myocardial Infarction by Yuanyuan Pei, Miao Miu, Xue Mao, Wen Chen, Jihong Zhu

“…Previous studies reported that the expression of α-Klotho was decreased in AKI rodents, and supplement of α-Klotho alleviated kidney injury. Nevertheless, its effect has not been studied in patients presenting with AMI. …”
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Novel cardioprotective and nephroprotective combination in patients with type 2 diabetes and chronic kidney disease: perspectives of use by Yu. Sh. Khalimov, G. V. Semikova, Yu. A. Shutova

“…Chronic kidney disease (CKD) is a common complication of diabetes mellitus. …”
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BK virus associated nephropathy and severe pneumonia in a kidney transplanted adolescent with Schimke immuneosseous- dysplasia by Ali Düzova, Bora Gülhan, Rezan Topaloğlu, Fatih Özaltın, Ali Bülent Cengiz, Ayşe Filiz Yetimakman, Deniz Doğru, Şafak Güçer, Nesrin Beşbaş

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Identification of the key targets for sepsis-associated acute kidney injury by RNA sequencing combined with bioinformatics methods by Linghan Leng, Chenglin Wang, Yaxing Deng, Yingchun Hu

“…Lastly, CD74 was principally expressed in macrophages, while IL32 was mainly presented in T cells. Conclusion CD74 and IL32, as biomarkers for early diagnosis and prognostic evaluation of sepsis complicated with kidney injury, are highly expressed in macrophages and T cells, respectively, providing new diagnostic and prognostic targets for sepsis complicated with acute kidney injury.…”
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Landscape of the immune infiltration and identification of molecular diagnostic markers associated with immune cells in patients with kidney transplantation by Zhangxiao Xu, Xun Sun, Xiaobo Ma, Bo Tao, Jian Wu, Yunpeng He, Yuan Zhao, Hexiang Mao, Jie Yang, Dehui Jiang, Lijun Wang, Chao Song

“…Finally, differential analysis and quantitative real-time PCR suggested that CD8A, CRTAM, GBP2, WARS, and VAMP5 were upregulated in rejection samples compared to non-rejection samples. The present study identified five key infiltrating immune cell-related genes (CD8A, CRTAM, GBP2,WARS, and VAMP5) involved in kidney transplant rejection, which may explain the molecular mechanism of rejection in kidney transplantation development.…”
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Kidney Injury in Children Infected with HIV, Followed at the Teaching Hospital of Borgou (Benin): Epidemiological and Clinical Aspects by Séraphin Ahoui, Falilatou Agbeille, Gerard Kpanidja, Alphonse Noudamadjo, Muriel Fridzie Toutche, Bruno Leopold Agboton, Evariste Eteka, Jacques Vigan, Adedemy Julien Didier, Joseph Agossou

“…The average age was 8 ± 4.81 years and the gender ratio was 1:17. The frequency of kidney damage was 76.5%. Permanent proteinuria and at least two crosses on urine dipstick were present in 20.5%, leukocyturia in 2.6%, and proximal tubular dysfunction in 5.1%. …”
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Case Report: Allogeneic adipose-derived mesenchymal stem cells for severe feline chronic kidney disease by Yizhe Song, Yuyang Liu, Yu Yu, Ying Wang, Yunpeng Mu, Siyu Wang, Wanting Han, Hailing Zhang, Wenzheng Zhang

“…A 10-year-old neutered male Ragdoll cat presented with symptoms of anorexia, nausea, vomiting, lethargy, and progressive weight loss. …”
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Reversal deterioration of renal function accompanied with primary hypothyrodism by Dragović Tamara

“…Serum thyrotropin and thyroxin levels measurement should be done in all cases of renal failure with undefined renal desease, even if the typical clinical presentation of hypothyroidism is absent. Thyroid hormone assays sholud also be performed in all patients with chronic kidney disease whose kidney function is rapidly worsening.…”
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A rare presentation of Sjogren\'s syndrome with ascites and liver fibrosis in a young woman: a Case report by Mohammad Reza Farzaneh Far, Maryam Miri, Farimah Naghibian, Forouzan Amerizadeh, Masoumeh Salari

“…Initial tests demonstrated leukopenia, anemia, and thrombocytopenia, as well as normal liver and kidney function.  Ascitic fluid analysis A indicated liver involvement, and imaging displayed significant fibrosis in the liver. …”
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Giant Bilateral Renal Angiomyolipomas and Lymphangioleiomyomatosis Presenting after Two Successive Pregnancies Successfully Treated with Surgery and Rapamycin by Ramón Peces, Emilio Cuesta-López, Carlos Peces, Rafael Selgas

“…It also stresses the potential for preservation of renal function despite successive bilateral renal surgery of giant AMLs. …”
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A Complex Presentation of Multiple Myeloma With Renal Complications in a Young Female: Diagnostic Challenges and Treatment Approach by Hem Prajapati, Yash M. Patel, Ajay C. Parmar, Sahaj Y. Patel, Tasin Mohammedyakub Shaikhjiwala

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Bilateral Ureteral Lithiasis and Postrenal Acute Kidney Injury: A Rare Complication of Diabetic Ketoacidosis in a Child by Fabio Rotondo, Sofia Siena, Maria Rosa Pastore, Pasquale Pio Maccarone, Morena Luce Mansueto, Irene Rutigliano

“…In patients with severe DKA, we recommend routine monitoring of kidney function with a low threshold for CT imaging whenever there is an unexpected rise in creatinine, oliguria/anuria, or lumbar pain. …”
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Features of pregnancy after simultaneous pancreas-kidney transplantation in patient with type 1 diabetes mellitus. Case report by Madina I. Yevloyeva, Darya U. Savitskaya, Anastasia S. Severina, Minara S. Shamkhalova, Natalia P. Trubitsyna, Marina V. Shestakova

“…Simultaneous pancreas and kidney transplantation the best way to restore normoglycemia and renal function in patients with type 1 diabetes mellitus and terminal chronic kidney disease. …”
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Crosstalk between macrophages and adjacent cells in AKI to CKD transition by Yanping Lin, Qian Yang, Rui Zeng

“…Acute kidney injury (AKI), triggered by ischemia, sepsis, toxicity, or obstruction, is marked by a rapid impairment of renal function and could lead to the initiation and advancement of chronic kidney disease (CKD). …”
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Successful pregnancy in a woman of late reproductive age with type 1 diabetes mellitus after combined pancreas — kidney transplantation by E. I. Prokopenko, F. F. Burumkulova, I. G. Nikolskaya, T. S. Kovalenko, V. A. Petrukhin

“…A healthy girl was born with weight of 2140 g, height of 48 cm, Apgar score 7/8 points. The mother’s function of the kidney and pancreas grafts remained normal. …”
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POEMS syndrome presenting with Vibrio vulnificus–like cutaneous lesions: a CARE guidelines-compliant case report by Xiaomei Li, Xiaomei Li, Bihong Lin, Liping Lin, Conghua Song

“…Laboratory workup revealed thrombocytosis, hypoalbuminemia, acute kidney injury, an IgA-λ monoclonal band on serum immunofixation, and a markedly elevated VEGF level (729.7 pg.…”
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A comparative study of clinical outcomes and risk factors of tuberculosis in kidney transplant recipients from deceased donors by Hedong Zhang, Mingda Zhong, Shanbiao Hu, Liang Tan, Longkai Peng, Xubiao Xie, Gongbin Lan

“…While standard anti-TB therapy achieved good overall patient survival, it takes a toll on kidney function which underscores the importance of close kidney function monitoring and delicate immunosuppressant management during TB treatment. …”
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