Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways by Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh

“…Furthermore, reporter assays showed resveratrol's activation of antioxidant response via nuclear factor erythroid 2-related factor 2 (NRF2)-mediated, leading to upregulation of transcription factor EB/transcription factor E3 (TFEB/TFE3), master regulators of lysosomal function. In fibroblasts pre-loaded with melanosomes, resveratrol reduced melanosome content compared to control by day 3. …”
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Techniques for Suppressing Mineral Dust Aerosol from Raw Material Stockpiles and Open Pit Mines: A Review by Hsin-Chieh Kung, Wan-Ching Lin, Bo-Wun Huang, Justus Kavita Mutuku, Guo-Ping Chang-Chien

“…Wet techniques are more versatile than dry methods for large stockpiles requiring constant loading and offloading. Chemical agents, including organic biopolymers, chemical surfactants, and inorganic, have higher dust suppression efficiency than plain water due to higher hygroscopicity and agglomeration potentials. …”
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Investigation of the lateral performance of trapezoidal double corrugated steel shear walls with two different corrugation angles by Yuanyuan Hu, Xianhui Yan

“…Abstract This research explores the lateral behavior of trapezoidal corrugated steel shear walls (CSSW) with double plates with two different corrugation angles by employing cyclic loading in the ABAQUS finite element software. The samples studied in this research were a one-story, one-span frame with three trapezoidal corrugated double plates with angles of 30, 45, and 60°. …”
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Multi-Scenario Progressive Planning Optimization of Shared Energy Storage Under Dual-Carbon Goals by ZHANG Ting, MA Yuze, WU Yunna

“…The operation strategy and progressive planning-optimization model for six scenarios of lithium battery-supercapacitor shared energy-storage system under the coordination of multiple flexible-regulation resources，such as smoothing fluctuations，peaking and valley filling，alleviating transmission and distribution circuit congestion and delaying grid upgrading，reducing wind and power rejection，achieving supply-and-demand balance，and reducing load cutting，are proposed. Additionally，a scientific and effective solution method is proposed to facilitate the dynamic construction of new power systems. …”
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Design and Fabrication of a Manually Operated Paver Block Making Machine. by Ddamba Timothy

“…Paver blocks are a building material intended for paving paths, sidewalks, and other similar objects with small and medium mechanical loads. For producing the best quality paver blocks, it is necessary to use a paver block machine. …”
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Design And Fabrication of a Manually Operated Paver Block Making Machine. by Ddamba Timothy

“…Paver blocks are a building material intended for paving paths, sidewalks, and other similar objects with small and medium mechanical loads. For producing the best quality paver blocks, it is necessary to use a paver block machine. …”
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Assessment of Impacts of Wastewater Discharge in River Rwizi in Mbarara City. by Niwenyesiga, Dison

“…Efforts should thus be directed towards best management practices for the reduction of wastewater loads in the area.…”
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The clinical value of computed tomography Hounsfield unit for diagnosing palpable inguinal lymph node metastasis in patients with penile cancer by Yu Li, Yu Chen, Gansheng Xie, Gang Li, Huming Yin

“…The average ACE-CT HU (cutoff: 40.5) had the highest accuracy as 0.857, and maximum NC-CT HU (cutoff: 51.5) had the highest sensitivity of 0.897.ConclusionILN CT HU was clinically valuable for the diagnosis of palpable ILN metastasis in patients with newly diagnosed penile cancer.…”
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Machine learning identifies the association between second primary malignancies and postoperative radiotherapy in young-onset breast cancer patients. by Yulin Lai, Peiyuan Huang

“…SPSMs were more common in YWBC individuals who were black, had a lower median household income and had fewer lymph nodes examined. …”
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Induction of labour outcomes in a tertiary hospital: the Ghanaian cervix and misoprostol 25ug (GCAM-25 STUDY)—a cross-sectional study by Teresa Aba Mensah, Kwaku Asah-Opoku, Kwame Adu-Bonsaffoh, Evans Kofi Agbeno

“…Results Among 168 women analysed, 138/168 participants (82.1%) had vaginal delivery and 30/168 participants (17.9%) had caesarean section. …”
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Pembrolizumab and Pemetrexed for Older Patients With Nonsquamous NSCLC and Programmed Cell Death-Ligand 1 Tumor Proportion Scores of Less Than 50% by Yoshihito Kogure, MD, PhD, Hiroya Hashimoto, PhD, Haruko Daga, MD, PhD, Yasushi Fukuda, MD, Akihiro Bessho, MD, PhD, Tadaaki Yamada, MD, PhD, Yukihiro Toi, MD, Tomoki Kimura, MD, PhD, Hiroshige Yoshioka, MD, PhD, Koichi Azuma, MD, PhD, Naoki Furuya, MD, PhD, Yasutaka Fukui, MD, PhD, Akiko M. Saito, MD, PhD, Nobuyuki Yamamoto, MD, PhD, Hideo Saka, MD, Masashi Kondo, MD, PhD

“…Methods: This multicenter, open-label, phase 2 trial involved 42 institutions across Japan. Eligible participants had metastatic or recurrent nonsquamous NSCLC without sensitizing EGFR or ALK alterations, were aged 75 years or above, had a programmed cell death-ligand 1 tumor proportion score of less than 50%, had not undergone systemic chemotherapy, and had an Eastern Cooperative Oncology Group performance status of 0 or 1. …”
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Associations of four obesity indices with diabetes mellitus in Korean middle-aged and older adults using the Korean Genome and Epidemiology Study (KoGES) by Yiseul Lee, Nam-Kyoo Lim, Hyun-Young Park

“…For IDI and cfNRI, WHR had the highest values among all age groups. The AUC of the ROC curve showed that the WHR had the highest value in all age groups. …”
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Hip Arthroscopy for Femoroacetabular Impingement Syndrome: Preoperative Radiographic Findings and Risk Factors for Reoperation at 3–6 Years Postoperatively by Andrea H. Johnson, Laura A. Stock, Jane C. Brennan, Justin J. Turcotte, Benjamin M. Petre

“…Results: By the end of the study period, 21 (6.0%) patients had undergone an RHA and 27 (7.7%) patients had undergone a THA. …”
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Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

“…PurposeEndoscopic retrograde cholangiopancreatography (ERCP) is a useful diagnostic and interventional tool in patients with obstructive jaundice. In patients who had subtotal gastrectomy, however, the implementation of ERCP has become more difficult. …”
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Explaining the Unexplained: Examining the Predictive Value of Semen Parameters, Sperm DNA Fragmentation and Metal Levels in Unexplained Infertility by Navdeep Kaur Ghuman, Kamla Kant Shukla, Srividhya Nandagopal, Sunil Raikar, Shailendra Kumar, Priyanka Kathuria, Dinesh Choudhary, Poonam Elhence, Pratibha Singh

“…Zinc concentration in the semen had a strong positive correlation (Point Biserial correlation coefficient = 0.831) with fertility, whereas lead and aluminium had a moderate negative correlation. …”
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The Association between Short-Term PM2.5 Exposure and Long COVID on the Respiratory System by Pornpun Sakunkoo, Chananya Jirapornkul, Naowarat Maneenin, Yuparat Limmongkon, Jetnapis Rayubkul, Kittipong Sornlorm, Rajitra Nawawonganun

“…Abstract Long COVID is an emerging medical condition defined by continuing symptoms reported by those who had previously recovered from COVID-19. The aforementioned symptoms impose significant effects on several physiological systems, especially the respiratory system. …”
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Frequency and characteristics of anemia in hypothyroid patients: A cross-sectional study by Abdullah S. Babaker, Reem M. Al-Qahtani

“…All patients aged 18-70 years who had received a diagnosis of hypothyroidism, ICD-10 code E03.9, and had undergone simultaneous blood tests for complete blood count and iron profile along with thyroid function tests were included in the study. …”
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Cord Blood pH and Lactate- A Step Ahead in Diagnosis of Fetal Acidaemia in Patients with Abnormal Cardiotocography by Indrani Mukhopadhyay, Sanjay Singh, Sushila Kachatti

“…RESULTS: In the non-reactive CTG group, 35.7% had early decelerations, 37.1% had variable decel-erations, and 17.1% had late decelerations (p<0.001). …”
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Adherence to First-Line Intravesical Bacillus Calmette-Guérin Therapy in the Context of Guideline Recommendations for US Patients With High-Risk Non-muscle Invasive Bladder Cancer by Franklin D. Gaylis, Bruno Emond, Ameur M. Manceur, Anabelle Tardif-Samson, Laura Morrison, Dominic Pilon, Patrick Lefebvre, Lorie A. Ellis, Hiremagalur Balaji, Andrea Ireland

“…Although 86.9% had adequate BCG induction based on the claims-based algorithm (SWOG, 73.6%), only 41.5% had adequate BCG induction and maintenance (SWOG, 1.6%). …”
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Adulthood consequences of spinal deformity surgeries in neurofibromatosis type 1 patients by Arihiko Tsukamoto, Koki Uno, Teppei Suzuki, Masaaki Ito, Keita Nakashima, Kenichiro Kakutani, Yoshiki Takeoka

“…However, it is not clear whether or not patients are able to lead a healthy social life as adults, and we investigated the surgical outcomes of patients who had reached adulthood after surgery. Methods Thirty-eight patients (16 males, 22 females) who had undergone spinal deformity surgery and had reached the age of 18 years at last follow up were included. …”
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